Abstract: A prosthetic capsular device configured to be inserted in an eye includes a housing structure and a ring structure. The housing structure includes a first side, a second side opposite the first side, a third side, a fourth side opposite the third side, a posterior side including a refractive surface, an anterior side opposite the posterior side, and a longitudinal axis. The first side, the second side, the third side, the fourth side, the posterior side, and the anterior side at least partially define a cavity configured to contain an intraocular device (e.g., an IOL). The anterior side includes an opening. The ring structure includes a ring structure portion extending radially outward from proximate one of an end of the first side and an end of the second side.

Abstract: A bone implant holding and shaping tray is provided. The tray includes a first segment having a distal end and a first surface sized to hold and shape at least a portion of the bone implant with bone material. The tray includes a second segment having a second surface sized to hold and shape at least a portion of the bone implant with bone material, the second segment having a proximal end configured to be coupled to the distal end of the first segment so as to extend the first surface to hold and shape the bone implant. Methods of making and using the bone implant holding and shaping tray are also provided.

Abstract: An orthopaedic surgical system for use in implanting a total knee prosthesis includes an adjustable tibial trial component that is movable in the anterior/posterior direction and rotatable when installed on the resected surface of a patient's tibia. A method of using such a system is also disclosed.

Abstract: An upgradable intraocular platform system includes (a) a substrate implantable in an eye; (b) an upgrade interface on the substrate for connection of at least one upgrade component for upgrading the platform system; and (c) a controller for controlling operation of the platform system.

Abstract: An intraocular lens has an optic body, a haptic element mounted on the optic body and having a haptic curvature and a plurality of recesses on the side of the haptic element facing the optic body, a first actuator configured to reversibly change the haptic curvature of the haptic element such that the haptic element is moved away from the optic body from a rest position, a brace arm mounted on the optic body and the longitudinal brace arm end which is configured to be provided a recess when the haptic element is in the rest position, and a second actuator configured to reversibly change, with a change in a property of the second actuator, a brace arm curvature of the brace arm such that the recess in which the longitudinal brace arm end is to be provided can be adjusted with the property of the second actuator.

Abstract: A technique can consistently achieve thicknesses of ?50 ?m for corneal tissue for for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ?50 ?m are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the precut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ?100 ?m, or more particularly ?50 ?m, to produce a corneal graft.

Abstract: An acetabular reconstruction prosthesis with a piling-cup system is provided, which includes an iliac posterior pile screw, an iliac anterior pile screw, a pubic pile screw, an ischial pile screw, abutments, a 3D (three-dimensional) printed porous titanium mesh cup, locking screws, nuts, and tail cap screws. Four pile screws are the iliac posterior pile screw facing posterior of the ilium, the iliac anterior pile screw facing iliac tubercle, the ischial pile screw running along ischium ramus, and the pubic pile screw running along pubic ramus. A stable prothesis support system is formed in the acetabular reconstruction prosthesis with a piling-cup system, which conforms to the biomechanical characteristics of physiological pelvis, reduces the risk of prosthesis loosening and dislocation, and improves long-term stability of the prosthesis through biological fixation.

Abstract: In some embodiments, a method for controlling an artificial iris may include receiving a measurement of light intensity detected by a sensor on or adjacent to the artificial iris. The method may include accessing a user-specific profile based on user calibration for determining one or more user-specific thresholds of light intensity of the user-specific profile. The one or more user-specific thresholds are associated with light intensities for triggering a change of light transmittance through the artificial iris. The method may include comparing the received measurement of light intensity to the one or more thresholds in the user-specific profile. The method may include determining, based on the comparing, whether to turn on or turn off one or more concentric rings of liquid crystals of the artificial iris for controlling an amount of light transmitted through the artificial iris.

Abstract: A modular augment cone system and methods of implanting the modular augment cone system. The system includes a main body cone a first cutout in the cone wall, and including a proximal end, a distal end, and a cone wall extending between the proximal and distal ends. A portion of the cone wall proximal to the first cutout includes an attachment feature. A first augment cone is positionable in the first cutout, the first augment cone including an attachment feature configured to mate with the attachment feature of the cone wall to attach the first augment cone into the first cutout. The main body cone can include a second cutout in the cone wall. In such systems, the modular augment cone system can include a second augment cone configured to mate with an attachment feature of the cone wall to attach the second augment cone into the second cutout.

Abstract: Systems and methods involving an intraocular implant with input and/or output electronics are described. In some embodiments, the system includes an intraocular lens having at least one optic operably coupled to a haptic, one or more input electronics on the haptic and/or the optic; and one or more output electronics on the haptic and/or the optic for receiving and/or transmitting data.

Abstract: An assembly for mounting a prosthetic nail for a human or animal digit. The assembly includes at least one transdermal anchor with an interior portion and an exterior portion. The interior portion may be positioned within tissue of the digit, and the exterior portion may extend outside the tissue of the digit. In another aspect, an exterior base may be positioned on a nail bed of the digit, and the exterior base may be coupled to the exterior portion of the transdermal anchor. The base may include a mount for removably a prosthetic nail to the base.

Abstract: A multicomponent implant system includes a multicomponent implant comprising a base plate and a load plate. The base plate includes a bone facing surface and a base plate interface surface. The load plate includes a load plate interface surface and a load bearing surface, the load bearing surface being substantially parallel to the load plate interface surface and having a contour substantially corresponding to a contour of a removed portion of the articular surface. Both the load plate interface surface and base plate interface surface have a contour substantially corresponding to the contour of the load bearing surface. The load plate is configured to be advanced in an arcuate direction to slidably couple the load plate to the base plate after the base plate has been secured within the first excision site by an anchor.

Abstract: The present disclosure relates to holders for protecting intraocular lenses and methods of use. The holder includes a posterior wall and an annular wall extending anteriorly from the posterior wall and having an anterior edge. An internal space is defined by the posterior wall and the annular wall. The internal space is sized to receive a lens body of the intraocular lens. The holder also includes a locking feature configured to secure the intraocular lens. At least a portion of the locking feature is anterior to the intraocular lens when positioned in the holder.

Abstract: Provided herein are devices and methods for treating inflammation and pain of articular joints (e.g., the knee). An implantable device includes an elongate body extending from a proximal end to a distal end, a flange disposed at the proximal end, a bore extending from an opening at the proximal end into the elongate body, one or more fixation members disposed on an outer surface of the elongate body, and a payload (e.g., a drug-polymer core) having a therapeutic agent disposed within the bore. The payload has a substantially constant surface area on an exposed portion throughout elution of the therapeutic agent after the implantable device is implanted in a body. The therapeutic agent is configured to elute using zero-order kinetics, constantly and continuously at an amount that is above a predetermined lower threshold and does not exceed a predetermined upper threshold unlike a pulse-dose injection.

Abstract: An exchangeable optics system includes an intraocular base that can be fixed within an eye. The intraocular base includes one or more couplers and a supporting structure. The one or more couplers releasably couple to an exchangeable optic and can include magnetic material. The supporting structure can include haptics and a main structure that physically supports the exchangeable optic. The intraocular base can include a fixed lens within or on the main structure. The exchangeable optic can include corresponding one or more couplers, which may be formed of magnetic material.

Abstract: A percutaneous heart valve prosthesis including a collapsible valve body frame has a first end and a second end. The valve body frame is formed by a plurality of sub-frame members, each sub-frame member having a general form of a diamond with acute-angled vertices and oblique-angled vertices, wherein adjacent sub-frame members are joined at the oblique-angled vertices. A flexible skirt made from a non-biologic material extends around a periphery of the valve body frame. A one-way valve including a plurality of flexible valve leaflets is positioned within the valve body frame. The first end of the valve body frame is sized to pass through a valve orifice associated with a heart valve to be replaced and the second end of the valve body frame is sized so as not to pass through a valve orifice.

Abstract: A tibial implant includes one or more stiffness-modifying features to reduce the stiffness of one or more sections of the tibial implant. The stiffness-modifying features may include slots, recesses, or passageways defined in various locations of the tibial implant to selectively reduce the stiffness of a tibial insert and/or tibial base of the tibial implant.

Abstract: A liner is arranged for use in prosthetic and orthopedic devices. The liner defines first and second end portions, and inner and outer surfaces. The liner includes an inner layer having a frictional component and forms at least part of the periphery of the inner liner surface. The inner layer defines a plurality of apertures. A porous element is in communication with the inner liner surface and is connected to the inner layer such that the apertures permit a transfer of air from the inner surface to the porous element. A base layer adjoins the porous element and extends between the first and second end portions of the liner.

Abstract: An ophthalmic device includes an optic including an optic axis and a closed-loop haptic structure coupled to the optic via a frame surrounding the optic, the closed-loop haptic structure including a closed loop extending from first and second attachment points to the frame. The closed loop includes a first hinge and a second hinge. The first hinge has a first section having a first component extending in a first angular direction, a second section having a second component extending in a second angular direction opposite to the first angular direction, and a first connecting section between the first section and the second section. The second hinge has a third section having a third component extending in the second angular direction, a fourth section having a fourth component extending in the first angular direction, the fourth section being connected to the second section to form the closed loop.

Abstract: A non-patient specific implant for neuroplastic surgery is provided. The non-patient specific implant includes a three-dimensional mesh. The three-dimensional mesh comprises titanium. The three-dimensional mesh is pre-folded. The three-dimensional mesh is configured to replace a space for a hard tissue and/or a space for a soft tissue. The three-dimensional mesh has a three-dimensional triangular shape.