Abstract: Lenses and methods are provided for improving peripheral and/or central vision for patients who suffer from certain retinal conditions that reduce central vision or patients who have undergone cataract surgery. The lens is configured to improve vision by having an optic configured to focus light incident along a direction parallel to an optical axis at the fovea in order to produce a functional foveal image. The optic is configured to focus light incident on the patient's eye at an oblique angle with respect to the optical axis at a peripheral retinal location disposed at a distance from the fovea, the peripheral retinal location having an eccentricity between ?30 degrees and 30 degrees. The image quality at the peripheral retinal location is improved by reducing at least one optical aberration at the peripheral retinal location. The method for improving vision utilizes ocular measurements to iteratively adjust the shape factor of the lens to reduce peripheral refractive errors.

Abstract: An intraocular lens (IOL) configured to support a first optic for functioning as a single lens IOL and configured to support a second optic for functioning as a dual optic IOL. The base includes a first optic for providing a base power. A recess in an anterior rim of the base is configured for positioning a radial extension of a second optic. The geometry of the recess is configured to securely couple to the radial extension to prevent rotation of the second optic relative to the base and prevent tilting of the second optic relative to an optic axis.

Abstract: A device for the repair of a phalangeal joint comprises a first anchor, a second anchor, and a flexible spacer connecting the first and second anchors. The flexible spacer comprises a plurality of elongate fibers extending axially or criss-crossed between the first and second anchors and a polymeric matrix interspersed with the plurality of elongate fibers. Specifically, a prosthetic metatarsophalangeal joint device comprises a porous metallic metatarsal bone anchor, a porous metallic phalangeal bone anchor, and a polymeric spacer element comprising parallel or criss-crossed elongate fibers that can connect the metatarsal bone anchor and the phalangeal bone anchor. Methods for manufacturing prosthetic joint devices comprise using three-dimensional printing processes or molding processes.

Abstract: A minimally invasive ab interno triple surgery for open-angle glaucoma comprises knotting and fixing a suture at the head end of an optical fiber catheter; performing miosis with carbachol, injecting the viscoelastic into the anterior chamber, making a lateral incision at the infratemporal corneal limbus, and placing the optical fiber catheter; cutting the Schlemm's canal on the nasal side of the anterior chamber, inserting an optical fiber into the incision on the Schlemm's canal, and cutting off the suture; injecting the viscoelastic to expand while retreating the microcatheter, and regularly injecting the viscoelastic; making a conjunctival flap on the eye and nose side, performing anterior chamber paracentesis, clamping out the suture using intraocular microforceps, and knotting in the sclera tunnel; and suturing the conjunctival flap using the suture, coating the eyes, and covering the eyes with gauze to finish the surgery.

Abstract: A support device for supporting a biological membrane includes a support bar that is elongated, that extends along a length direction and that has at least one cylindrical surface extending along the length direction for supporting the biological membrane. A method of using the support device, which is suitable for mounting on a space of a bone defect structure of a human body and which is suitable for supporting a biological membrane, is also disclosed.

Abstract: The present invention relates to an aspherical multifocal intraocular lens with large depth of field, the intraocular lens having an anterior optical surface and a posterior optical surface, wherein one optical surface is distributed with an aspherical surface which plays a role of expanding the depth of field, and the other optical surface is distributed with a multifocal structure which plays a role of providing two or more focal points. The aspherical surface provides a depth of field matching with an absolute value of a difference in refractive power of at least one pair of adjacent focal points of the two or more focal points provided by the multifocal structure. The aspherical surface, on the one hand, allows a continuous visual range between the focal points and, on the other hand, extends near vision in the direction of near focal point through the depth of field, thereby enabling continuous, uninterrupted full-range vision and adequate near vision.

Abstract: An innovative dome toe resurfacing system for performing metatarsophalangeal joint replacement is disclosed. The present invention comprises a prosthetic implant for metatarsophalangeal joint, and one or more cone extensions that covers portions of the prosthesis that extends into the metatarsal bone and phalanx bone. The cone extensions include a plurality of ridges that will catch bone on insertion and provide a press fit. The present invention also includes a cone and cup reaming system wherein one or more reamers will ream a cone/cup shape for the articular surfaces, and prepare the metatarsal and phalangeal canals for the insertion of the cone extensions. The cone extensions have ends that fit the reamed cone/cup shape wherein the cone/cup shape resembles the natural anatomy of articular surfaces of metatarsophalangeal joint.

Abstract: Surgical implants and methods to improve, support, or help to preserve vision by altering the axial length or curvature of an eye are provided. Staphyloma supporting devices or implants can be of unitary construction from a single base material such as titanium alloy and can have a macular indenter plate wider than the implant body and an anchor structure wider than the macular indenter plate. A compound concavity scleral contact surface can approximate the outer surface of the eye with an anterior radius of curvature and can restore macular shape and axial length with a second posterior radius of curvature that can be less than the anterior radius of curvature.

Abstract: Various embodiments of a coupler and an intradiscal implant for alignment and fusion of the sacroiliac joint are described herein.

Abstract: An ophthalmic lens comprising an anterior surface and a posterior surface, at least one of the anterior surface and posterior surface including a first surface region corresponding to a photopic aperture of a pupil and a second surface region corresponding to a difference between the photopic aperture and a mesopic aperture of the pupil. A first microstructure pattern formed in a the first surface region, the first microstructure pattern introducing a phase perturbation into an optical path of incoming light such that a full depth of focus for photopic vision is provided.

Abstract: A method of implanting a percutaneous heart valve prosthesis via a catheter. The heart valve prosthesis includes a valve body frame made of a nickel-titanium alloy. The valve body frame is collapsible for fitting within the catheter. A flexible skirt is sutured to the valve body frame for blocking retrograde blood flow. A one-way valve is positioned within the valve body frame for permitting blood to flow from a first end of the valve body frame to a second end. The one-way valve is preferably formed by three flexible valve leaflets made from a pericardial material. A plurality of barbs is spaced about the periphery of the valve body frame. Each of the prongs points toward the first end of the valve body frame for preventing migration of the heart valve prosthesis towards an atrium of the heart.

Abstract: This document describes intraocular lenses and methods for their use. For example, this document describes intraocular lenses that are shaped with a concave posterior peripheral portion that mitigates occurrences of dysphotopsia. The intraocular lenses described herein are designed to reduce positive and negative dysphotopsias after cataract surgery.

Abstract: A tibial implant for knee arthroplasty includes a tibial plate, a tibial keel, and at least one anchoring projection. The tibial plate is sized and shaped for placement on a proximal end of a tibia of a patient. The tibial plate includes opposite proximal and distal surfaces with the distal surface configured to engage the end of the tibia. The tibial keel extends distally from the distal surface of the tibial plate and is configured to be inserted into the proximal end of the tibia. The anchoring projection extends distally from the distal surface of the tibial plate and is configured to be inserted into the proximal end of the tibia.

Abstract: Provided herein are devices used to reconstruct a natural lens capsule after a cataract surgery. The device has a ring-shaped rigid component, a ring-shaped flexible component and a groove disposed on an inner surface of the rigid component. The rigid component has a distal end attached to the ring-shaped flexible component and a proximal end that lies against Wieger's ligament when fitted within the natural lens capsule. The ring-shaped flexible component has a proximal end that is attached to the distal end of the rigid component and a distal end that contacts an anterior surface of the natural lens capsule when fitted therein. The groove is disposed to receive optics of an intraocular lens and/or the ledge is disposed to secure haptics thereof.

Abstract: Described herein is a device for lowering intraocular pressure, the device comprising a plate structure comprising an upper surface opposite a lower surface, the plate structure formed from a multi-directional plate having a plate thickness ranging from about 1 nm to about 1,000 nm.

Abstract: Disclosed is a surgical targeting device for assisting placement of an elongated guidance member in a bone. The targeting device comprises a bottom portion having a dome-shaped convex outer surface and comprising a guidance through-hole extending along a guidance through-hole central axis for receiving the guidance member. A top portion of the targeting device is configured to be gripped by a tool. Further, a surgical system is disclosed which comprises the surgical targeting device.

Abstract: The present disclosure provides an intraocular lens (IOL) or ophthalmic device including an optic and at least one haptic, at least a portion of which is formed from a photoresponsive shape memory polymer network, such as a polydomain azo liquid crystalline polymer network (PD-LCN). The present disclosure further provides systems and methods for adjusting the position of such an IOL or other ophthalmic device using polarized laser radiation.

Abstract: A gimbal handle assembly including: an inner gimbal and an outer gimbal that are concentrically linked and have pivot axes that are orthogonal relative to each other, a spool coupled to and rotatable around the outer gimbal, and a plurality of draw lines attached to the spool in a circumferential configuration, wherein rotation of the spool and/or rotation of the spool and the outer and inner gimbals increases or reduces tension in the draw lines. Also disclosed are a transcatheter valve delivery assembly that includes the gimbal handle assembly, a multi-lumen catheter, a sleeve attached to a distal end of the multi-lumen catheter, and a transcatheter heart valve including an expandable valve frame. Methods of delivering the transcatheter valve to a subject are described, wherein pitch and yaw orientations of the transcatheter valve can be precisely controlled with enhanced degrees of freedom.

Abstract: Cellulose-reinforced hydrogels may include a cellulose nanofiber network and an interstitial hydrogel portion within interstitial regions of the cellulose nanofiber network, the interstitial hydrogel portion comprising polyvinyl alcohol (PVA), wherein the hydrogel component has a crystallinity of 20% or greater.

Abstract: The invention features a glenoid (shoulder socket) implant prosthesis, a humeral implant prosthesis, devices for implanting glenoid and humeral implant prostheses, and less invasive methods of their use for the treatment of an injured or damaged shoulder.