Abstract: A catheter insertion device and method for insertion. The catheter insertion device can include a housing, a needle attached to a needle carrier, a catheter including a catheter shaft attached to a catheter hub, and a guidewire. The guidewire can include a coil tip positioned in a lumen of the needle. The method for insertion can include inserting a distal end of the needle and the catheter shaft into a blood vessel of a patient, advancing the coil tip out of the needle lumen and into the blood vessel, advancing the catheter over the guidewire, and withdrawing the guidewire and the needle from the catheter. The coil tip can include a straightened configuration and a coiled configuration. The coil tip can transition from the straightened configuration in the needle lumen to the coiled configuration in the blood vessel.

Abstract: A medical device fluid sensing system in provided. The system includes a transmitter array positioned in association with a fluid maintaining device, such as a reservoir in a cassette. Electrical circuitry is connected to the transmitter array and configured to cause the transmitter array to transmit light energy at a predetermined wavelength and producing a desired absorption coefficient based on expected conditions within the fluid maintaining device. The system also includes a receiver array configured to receive light energy transmitted through the fluid maintaining device and originating from the transmitter array, and a controller configured to determine fluid level in the fluid maintaining device based on conditions sensed by the receiver array. In one embodiment, three transmitters and three matching sensors are provided in a surgical cassette, and when optical energy having predetermined characteristics is provided to the transmitter array, the presence or absence of fluid is determined.

Abstract: A medical connector includes a cap having a male connector connecting part; a holder having a medical instrument connecting part; and a valve body configured to block the male connector connecting part and configured to be pushed in by a male connector such that a liquid flow channel in the male connector communicates with a liquid flow channel in the medical instrument connecting part when the male connector is connected to the male connector connecting part. The cap and the holder are linked to each other so as to be rotatable about an axis of the male connector connecting part.

Abstract: An assembly for a drug delivery device is provided, wherein the assembly comprises an actuator which is configured to perform a setting movement in order to set a dose and which is configured to perform a dispense movement in order to dispense a dose and a piston rod which is configured to be moved in a distal direction in order to dispense a dose, and a snap feature which is configured to snap into engagement with the piston rod. The snap feature may be configured to inhibit a dispense movement of the actuator and/or a setting movement of the actuator when a maximum amount of medication has been delivered.

Abstract: A bi-directional cannula feature capture mechanism is described herein. Generally, the capture mechanism comprises an inner housing, an outer housing, and a cannula. The inner housing comprises a proximal and a distal cannula feature mating component. The outer housing is adapted to slidably receive the inner housing in a proximal direction. Additionally, the cannula extends through the inner housing and the cannula's feature has a proximal engagement and a distal engagement. The proximal and distal engagements are respectively configured to irreversibly engage the proximal and distal cannula feature mating components when the cannula tip is moved into a shielded position.

Abstract: A method may include generating a first plurality of insulin delivery profiles that include a first series of insulin delivery actions spanning a first time interval, projecting a first plurality of future blood glucose values for each profile of the first plurality of profiles using up-to-date blood glucose levels, selecting one of the first plurality of profiles based upon comparing future blood glucose values for each profile and target blood glucose levels, delivering insulin for a second time interval that corresponds to a first action of the first profile, generating a second plurality of insulin delivery profiles for a third time interval, projecting a second plurality of future blood glucose values for each profile of the second plurality of profiles for the third time interval, and delivering a second dose of insulin for a fourth time interval shorter than the third time interval.

Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

Abstract: Disclosed are methods of subretinal delivery of therapeutic compositions to the eye of a mammal. Also disclosed are devices useful for the subretinal delivery of therapeutic compositions to the eye of a mammal.

Abstract: Methods and devices described for improved catheters including those having a deflectable section to allow for expansion while maintaining flow through a vessel.

Abstract: An apparatus (1) for providing agitation inside a patient's body cavity (C) is such that substantially all the fluid and/or content present in the body cavity (C) is agitated and comprises a gas source (6, 7); means for delivering gas (2) from the gas source (6, 7) into a patient's body cavity (C); and means for recovering gas (9) from the patient's body cavity (C). A gas-fluid separation device (9) and a securing device for use with the apparatus (1), a method for providing agitation inside a patient's body cavity (C), a method for administering a therapeutic fluid into a patient's cavity (C), a method for securing the agitation apparatus (1) to a patient using the securing device and a method for the separation of a gas from a fluid using the gas-fluid separation device (9) are also disclosed.

Abstract: An injection device has a housing which includes a first housing part and a second housing part. The injection device has a receptacle for an injection needle. The receptacle is connected to a drive unit which moves the receptacle between proximal and distal end positions relative to the second housing part. The first housing part has a set piece for placing on the skin before triggering an injection. The first housing part is permanently fastened with respect to the second housing part. In a method for making the injection device, the first housing part is positioned on the second housing part so that the receptacle has a specified position relative to the set piece in the proximal end position thereof, and that the first housing part is permanently fastened in this position opposite the second housing part. A defined insertion depth can thus be ensured.

Abstract: A cannula assembly having a plurality of outwardly-biased flexible fins capable of inward movement such that the fins converge upon insertion of a trocar device. The fin embodiment including a slot formed therein, with a corresponding raised feature on the trocar shaft capable of engaging the slots. Inward movement of the trocar within the cannula lumen causes the fins to converge. An additional embodiment utilizes outwardly-biased flexible fins that lock together in a closed position, with corrugated features in the fin inner surface that contact the trocar shaft such that, upon insertion of the trocar, the fins unlock and splay outward. One or more of the flexible fins also including one or more penetrations for accepting a biasing device for altering the biasing force of the fin.

Abstract: A pre-curved catheter tube of a catheter assembly or other elongate medical device and methods for forming such a device using a heating procedure is disclosed. Pre-curving of the catheter tube is desirable to impart to the catheter assembly a desired positional configuration when the catheter assembly is inserted into a patient. The heating procedure may include heat sterilization procedures commonly used to sterilize medical devices prior to use. In one embodiment, therefore, a catheter assembly is disclosed, comprising an elongate catheter tube defining at least one lumen, and a tube constraint. The tube constraint is included with the catheter assembly and is configured to temporarily constrain the catheter tube in a curved configuration during a heating procedure of the catheter assembly so as to permanently form the catheter tube in the curved configuration after the heating procedure is complete and the catheter tube is released from the tube constraint.

Abstract: A pump set for use with a pumping apparatus having a rotor with a plurality of rollers mounted on the rotor rotatable about an axis of rotation is disclosed. The pump set comprises a cassette body comprising a stator member with a fixed portion secured to the cassette body, a second portion opposite the fixed portion, a reaction surface and a second surface opposite the reaction surface, the reaction surface defined between the fixed portion and the second portion, and a tube secured to the cassette body, at least a portion of the tube is disposed against the reaction surface.

Abstract: A device for emptying stool from the rectum of a patient by means of a shaft body which is introduced into the bowel via the anus and is able to buckle or fold axially and radially, and which is provided with a dumbbell- or hourglass-shaped balloon body for assuring the transanal positioning of the device. The invention comprising a design of, and choice of material, for the shaft body and the balloon envelope, and by the positioning of the balloon body on the shaft body, wherein the axial deflection of the free forward end of the shaft body is limited and an uncontrolled deflection of the shaft is prevented, and the probability of perforation of the bowel wall under the effect of force acting on the shaft body from an axial direction is reduced by the intestinal tube.

Abstract: The present invention is directed to a body temperature controlling system comprising at least one member receiving a flow of gas from at least one blower in communication with said at least one member, said at least one member directing said flow of gas onto a wearer thereof.

Abstract: Provided is a device for surely and easily applying a microneedle patch to a skin. In a case body 2, a pressing member 3 having a tip surface 3a is disposed such that the pressing member is biased in a first direction X1 by a first biasing member. The movement in the first direction X1 is locked by a locking member 7 and a locking part 3g so that the pressing member 3 is brought into a locked state. The locked state is released by pressing a tip of a lock-releasing member 11 against the skin. When the locked state is released, a tip surface 3a of the pressing member 3 is moved in the first direction X1 and the tip surface 3a applies the microneedle patch to the skin.

Abstract: The present invention relates to a dispensing mechanism (2) for delivery of pharmaceutical forms (4) into body holes and an applicator (I) comprising the novel dispensing mechanism (2). The pharmaceutical form dispensing mechanism (2) Comprises a rod (2A) connected to a flexible member (2B). One end of the rod is free from constraints in order to allow its axial movement. The other end of the rod is cooperatively connected to said flexible member (2B). The flexible member has a rounded or angular shape, being able to be deformed and being provided with shape memory. The flexible member (2B) extends in a direction perpendicular to the direction of a compression force applied to it and recovers its original shape when said compression force is withdrawn, thereby imparting, respectively, a forward or rearward movement to the rod (2A), namely when a part (2C) thereof is immobilized in the body (3) of the applicator.

Abstract: The present invention is an injection port with an articulated stopcock allowing a syringe to be connected to an IV line and, depending upon the orientation of the stopcock, allow (1) bidirectional flow of fluid through the stopcock into the IV line, (2) no flow or (3) unidirectional flow of fluid through the stopcock and into or out of the IV line. The invention is particularly useful for using a syringe for aspirating an IV line and then injecting a medicine from the syringe into the IV line. Once a syringe is connected, the invention allows one-handed manipulation of the articulated stopcock into the three orientations by simply moving the connected syringe into one of the three orientations, thereby eliminating the need for using two hands—one to operate the syringe and the other to operate the handle.

Abstract: A balloon for a balloon catheter includes a body section and cone sections. At least one of the cone sections defines a plurality of grooves spaced around the circumference of the cone section.