Abstract: An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.

Abstract: Embodiments herein include an insertion tool for inserting a medical device into another medical device, such as a hemostasis sealing valve, and related methods. In an embodiment, an insertion tool includes a guide sheath and a protection tube. The guide sheath can include a flared proximal end. The guide sheath can further include a central lumen. The guide sheath can further include a locking notch disposed on the inner surface between the proximal end and the distal end. The protection tube can include a flared proximal end. A portion of the protection tube can be situated within the central lumen of the guide sheath. The flared proximal end of the protection tube can be sized to fit within the locking notch and can have an outer diameter larger than portions of the inner surface immediately adjacent to the locking notch. Other embodiments are also included herein.

Abstract: A method may include displaying to a user an interface at which the user inputs a fear of hypoglycemia index (FHI), the FHI corresponding to an acceptable probability of a blood glucose level being below a threshold blood glucose level. The method may also include receiving blood glucose data for a person with diabetes (PWD). The method may additionally include calculating a probability of the PWD having a blood glucose level below the threshold blood glucose level based on the variability of the received blood glucose data. The method may also include setting one or more target blood glucose levels to align the probability of the PWD having a blood glucose level below the threshold blood glucose level with the acceptable probability associated with the user input FHI. The method may additionally include delivering insulin, using the insulin delivery device, based on the target blood glucose level.

Abstract: A needle assembly for transdermal administration including a substrate having a first surface and a second surface opposite to the first surface, and fine needles projecting perpendicularly from the first surface. The substrate has grooves on at least one of the first surface and the second surface, and the grooves are formed such that the substrate is deformable following a surface shape of a skin to allow axes of the fine needles to extend in a direction normal to the surface of the skin.

Abstract: A supplemental device for attachment to an injection device. A supplemental device for attachment to an injection device, the supplemental device comprising: a housing; an electromechanical switch arrangement, the electromechanical switch arrangement comprising: a main body; and a switching member, the switching member having a protrusion arranged to protrude from the main body so as to contact a surface of the injection device while the supplemental device is attached to the injection device; and a biasing member configured to bias at least a part of the main body of the electromechanical switch arrangement against the injection device while the supplemental device is attached to the injection device.

Abstract: A mask is provided. The mask includes an outer cover made of ultra-fine fibers and formed by hot-pressing, and the outer cover has a plurality of through holes for ventilation; a filter configured to filter air and disposed at a side of the outer cover adjacent to a user; and two sealing pads, each attached to a side of the filter adjacent to the user and configured to contact skins at two sides of a nose bridge of the user to seal gaps between the filter and the two sides of the nose bridge of the user.

Abstract: A microneedle skin care device includes a housing having a predetermined space formed therein; a sound wave module disposed inside the housing to provide sound wave vibration; a microneedle assembly configured to receive vibration of the sound wave module and vibrate in front and rear directions, the microneedle assembly having microneedles disposed at a front end; and a needle tip coupled to the front end of the microneedle assembly and having through-holes through which the microneedles selectively pass through formed corresponding to the microneedles.

Abstract: A method includes receiving up-to-date blood glucose data for a PWD, determining basal insulin dosages for the PWD based on a baseline basal rate, delivering the basal insulin dosages to the PWD, modifying a target blood glucose level based on variability of blood glucose data for the PWD, receiving a temporary override indicating a user preference to reduce the likelihood that the PWD has a hypoglycemic event or a user preference to reduce the likelihood that the PWD has a hyperglycemic event, determining a temporary target blood glucose level based on the input—greater than the modified blood glucose level if the preference is to reduce the likelihood of a hypoglycemic event—lower than the modified target blood glucose level if the preference is to reduce the likelihood that of a hyperglycemic event. The method includes delivering basal insulin for the temporary period of time based on the temporary target.

Abstract: The present invention relates to apparatus for topical application of material for cosmetic purposes (10). The apparatus for topical application of material (10) comprises measurement apparatus configured to measure a property of skin of a human or animal subject and actuating apparatus configured to change a permeability of the skin of the human or animal subject in dependence on the measured property of the skin. The apparatus for topical application of material (10) further comprises application apparatus configured to apply material for cosmetic purposes to the skin whilst substantially no iontophoretic current flows through the skin and after the permeability of the skin has been changed.

Abstract: Apparatus and methods for medicament delivery. The apparatus may include, and the methods may involve, a delivery device for delivering a target amount of the medicament from a distal end of the device. The device may include a rod for moving a plunger that discharges the medicament from the distal end. The device may avoid or reduce deformation of the plunger during the discharge. The plunger motion may be stopped by detent that interacts with the rod. The apparatus and the methods may provide an operator indication of progress of stages of operation. The device may feature triggers corresponding to stages of medicament displacement from the device, such as pre-delivery stages, including priming.

Abstract: A syringe assembly or inflation device that includes a detachable housing. A pressure-sensing syringe assembly or inflation device can include both a syringe barrel and a housing that is coupled to the syringe barrel in a locked configuration. The inflation device can transition from the locked configuration to the unlocked configuration in which the housing is separable from the syringe barrel. Related methods are also disclosed.

Abstract: Methods and devices described for improved catheters including those having a deflectable section to allow for expansion while maintaining flow through a vessel.

Abstract: A medical article, such as a catheter hub or extension set, is stabilized on a patient with a retainer and a dressing integrally attached to an anchor pad supporting the retainer. The catheter hub or extension set may be integrally formed with the retainer. The retainer may comprise a channel and an integral strap. The channel may include an abutment. One or more of the anchor pad, dressing, and catheter may comprise an antibacterial or antimicrobial agent.

Abstract: A catheter includes an inner layer, a reinforcement layer at least partially inside the inner layer or on an outer periphery of the inner layer, and an outer layer covering the inner layer and the reinforcement layer. The reinforcement layer has a wire wound so that a gap is present between adjacent portions of the wire. The inner layer has an uneven outer peripheral surface on which a protruded portion is formed in a location of the wire, and in which a depressed portion is formed in a location of the gap. The outer layer has a protrusion part that extends into the depressed portion of the inner layer, the protrusion part entering deeper than the reinforcement layer through the gap and extending in an axial direction of the catheter. The outer layer is not easily detached from the inner layer.

Abstract: A medical puncture needle includes: a distal end portion including a needle point; and a rod-like main body portion continuous with the distal end portion. The distal end portion includes a blade surface. The blade surface includes: a first blade surface portion on a front side of the distal end portion, the first blade surface portion being inclined with respect to a center axis of the main body portion and extending to the needle point, and a second blade surface portion on a back side of the distal end portion. When a virtual plane including the center axis of the main body portion is established, the second blade surface portion comprises a curved surface in which an angle with respect to the virtual plane in a cross section orthogonal to the center axis direction gradually increases toward the needle point side in the center axis direction.

Abstract: A method for discharging fluid from a syringe and for mitigating occlusion conditions includes actuating the plunger of a syringe into a barrel. The method monitors fluid pressure within the barrel of the syringe and determines that an occlusion exists when the fluid pressure exceeds a predetermined threshold. The method actuates the plunger out of the barrel by a predetermined amount in response to the detected occlusion and actuates the plunger of the syringe into the barrel until a measured fluid pressure within the barrel of the syringe exceeds another predetermined threshold.

Abstract: There is disclosed a fluid warming system (300) for warming intravenous fluid, comprising: a heater unit (304), including a heating element (314) and at least one temperature sensor; a heat exchanger unit (302), removably attachable to the heater unit (304), which includes an inlet (306) and an outlet (308) through which the fluid can pass, and a controller (316), programmed: to receive at least one temperature measurement (TCI, TCO) from said at least one temperature sensor in the heater unit (304); to compute a fluid flow rate (q), corresponding to the rate of flow of fluid from the inlet (306) to the outlet (308) of the heat exchanger unit (302), in dependence on the amount of electrical power (PH) supplied to the heating element and said at least one temperature measurement (TCI, TCO); and to control the electrical power (PH) supplied to the heating element in dependence on the computed fluid flow rate (q).

Abstract: A method for determining a position of a component in a medical apparatus along a travel distance. The method comprising the steps of generating light by a light source; fixing the component movably along a travel distance; providing a photosensitive sensor surface, and generating a silhouette of the component on the sensor surface by irradiating the component with light from the light source. Data relating to the silhouette is converted by a data processing unit into the position of the component along the travel distance. The component whose position is determined may comprise a stopper of a cartridge.

Abstract: An irrigated ablation catheter includes a shaft having a proximal end, a distal end, and an irrigation lumen therein. The catheter further includes an electrode assembly coupled to the distal end of the shaft. The electrode assembly includes an ablation electrode and a manifold. The manifold is coupled to each of the distal end of the shaft and the proximal end of the electrode. At least a portion of the manifold is constructed of a flexible material to allow the electrode assembly to deflect. The manifold includes a body, an inner cavity within the body configured for fluid communication with the irrigation lumen, and an irrigation port also within the body and configured for fluid communication with the inner cavity. The irrigation port extends from the inner cavity to the outer surface of the body, and is configured to allow for an irrigating fluid to be distributed from the manifold.

Abstract: A novel aromatherapy vaporization device is disclosed having a first and second housing with a heating chamber for receiving of phyto material. The heating chamber has an ambient air input port that receives ambient air that does not flow past hot electrical components when entering the heating chamber. An inhalation tube is coupled with the heating chamber for receiving of phyto material vapor therein in a second mode of operation and in a first mode of operation the inhalation tube is uncoupled from the heating chamber to allow for loading of phyto material therein.