Abstract: An injection device is for automatically squeezing injection liquid from a container and includes: a housing; an injection spring configured to cause squeezing of the injection liquid from the container; the injection device defining a longitudinal central axis and a proximal direction; a metering piston mounted so as to be movable in the direction of the longitudinal central axis of the injection device; the metering piston being configured to, when squeezing injection liquid, move in the proximal direction; a setting device for setting the quantity of injection liquid to be squeezed; an end stop which establishes a terminal position of the metering piston; and, the setting device having an adjustment unit configured to adjust the position of the end stop.

Abstract: The present invention is directed to a body temperature controlling system comprising at least one member receiving a flow of gas from at least one blower in communication with said at least one member, said at least one member directing said flow of gas onto a wearer thereof.

Abstract: A surgical injection device includes at least one tubular element defining a passageway. The passageway is configured for disposal of a selected volume of an agent and an evacuator disposed within the passageway. An actuator is engageable with the evacuator to entirely expel the selected volume of the agent from the passageway to a selected site. Spinal constructs, implants, systems and methods are disclosed.

Abstract: Drug delivery devices and methods of administering drugs to patients are provided. A device (50) includes a reservoir (60) containing a drug (58). The reservoir (60) is defined by a wall (64) having a water-permeable portion, such that the water-permeable portion permits water to enter the device (50) and contact the drug (58). A restraining plug (56) closes off an opening of the device (50) such that transient microchannels (62) form between an elastic portion (54) of the device (50) and the restraining plug (56), upon the generation of a sufficient pressure within the reservoir (60), to release the drug (58) from the device (50). Methods of treating patients for neurogenic detrusor overactivity resulting from a spinal cord injury and/or for idiopathic overactive bladder and urinary incontinence are also described.

Abstract: A gas control module for a gas-enhanced electrosurgical system. The gas control module has an inlet port, a first solenoid valve connected to said inlet port, a first pressure sensor, a first pressure regulator, a first flow sensor, a first proportional valve, a second flow sensor, a second solenoid valve, said second solenoid valve being a 3-way valve, a vent connected to said second solenoid valve, a second pressure sensor, a third solenoid valve and an exit port.

Abstract: An adhesive polymer matrix for the delivery of an active principle via iontophoresis. The matrix having a first face intended to be applied onto skin and a second face intended to cooperate with electrodes. The matrix comprises electrically conductive zones and at least one electrically insulating zone, each conductive zone being insulated from another conductive zone by an insulating zone. The techniques involve the use of an electric current in order to facilitate the transdermal diffusion of active substances, and relates more particularly to an iontophoresis device.

Abstract: A controller and associated sensor system for augmenting the automatic delivery of drugs is provided. The controller and associated sensor system is based on the detection and determination of particular physical lifestyle events. As a specific example, a pump augmentation system includes a six-axis accelerometer sensor, a gyroscopic pitch sensor and a controller. The controller is configured to receive motion data from the six-axis accelerometer sensor and orientation data from the gyroscopic pitch sensor. The controller provides a pump instruction signal for changing a delivery rate of a drug to a user based on the motion data and the orientation data. When the pump is an insulin pump, the pump augmentation system is an insulin pump augmentation system and provides accurate insulin control for controlling blood glucose levels of a user.

Abstract: Venous therapy methods and apparatus improve arterial or venous blood flow, for example in the legs. Venous therapy can reduce venous backflow and can improve arterial therapy such as that provided by intermittent pneumatic compression therapy.

Abstract: Enhanced confirmations for programming of touchscreen infusion pumps reduce the likelihood of users confirming pump parameters that have been mistakenly programmed. Following programming of a given pump parameter, an icon or image intuitively related to the pump parameter can be displayed on the touchscreen. To confirm programming of the parameter, the user can be required to trace the icon on the touchscreen. The user will therefore necessarily associate the confirmation step with the parameter being programmed and be far more likely to realize if a mistake has been made because the user was intending to program a different parameter than with simple confirmations involving the press of a confirmation button.

Abstract: A device for ablating target tissue of a patient with an ablative fluid is provided. An elongate shaft includes a proximal portion and a distal portion, and at least one fluid delivery element is attached to the distal portion. The device can be configured to ablate the duodenal mucosa of a patient while avoiding damage to the duodenal adventitial tissue. Systems and methods of treating target tissue are also provided.

Abstract: Embodiments of the present disclosure are directed to devices, systems, and methods for controlling environmental conditions for a volume of material. In some embodiments, a handheld, portable environmental control sleeve (ECS) is disclosed which is configured for controlling at least one environmental condition of a drug contained within a drug delivery or storage device (DDSD). The ECS includes an environmental control mechanism (ECM), thermal insulation material, at least one of a power source, a processor, at least one electrical contact, at least one indicator, at least one switch, at least one environmental condition sensor, a wireless transceiver, a phase change material and at least one heat dissipater. Upon the ECS receiving at least a portion of the DDSD, the at least one environmental condition of a drug contained within the DDSD is controlled by the ECM to be within a predetermined range.

Abstract: A balloon structure includes a proximal balloon portion having a first internal volume, a distal balloon portion having a second internal volume, and a central balloon portion disposed between and joined with the proximal and distal balloon portions. The central balloon portion has a third internal volume isolated from the first and second internal volumes. A first lumen is associated with the third internal volume to direct pressure to the third internal volume for inflation of the central balloon portion. At least one second lumen is associated with the first and second internal volumes to direct pressure to the first and second internal volumes for inflation of the proximal balloon portion and the distal balloon portion. Whereby, upon inflation, the central balloon portion dilates, or delivers other treatments to tissue in the passage, with the proximal and distal balloon portions limiting movement of the balloon structure in the passage.

Abstract: A gas conditioning unit for a surgical gas delivery device is disclosed, which includes a filter housing having an insufflation gas flow path for delivering insufflation gas to a body cavity and for facilitating pressure measurements from the body cavity, a pressurized gas flow path for delivering pressurized gas from a pump in the surgical gas delivery device to an internal nozzle in the filter housing that accelerates the pressurized gas and thereby generates a continuous pressure barrier that inhibits egress of insufflation gas from the body cavity, a vacuum return flow path for returning depressurized gas spent by the internal nozzle back to the pump under vacuum, an air entrainment flow path for drawing air into the body cavity to maintain a given pressure therein, and a smoke evacuation flow path for conveying smoke from the body cavity.

Abstract: A flexible medical needle for extended indwelling periods is provided. The medical needle apparatus includes a spine body and a flexible shaft portion. The spine body has a length between a first end, comprising a piercing tip, and a second end. The flexible shaft portion may be disposed on at least a portion of the spine body, forming a needle shaft having a passage along a portion of the length of the spine body. The spine body may also be coiled forming an axial passage within the spine body. In this latter embodiment, the flexible shaft portion surrounds the spine body. In each embodiment, the spine body is configured to facilitate bending, allowing for the medical needle to remain indwelling with reduced discomfort.

Abstract: A peritoneal dialysis (PD) system for infusing a volume of PD solution into a patient's peritoneal cavity in order to perform peritoneal dialysis on the patient includes a peritoneal cavity monitor (PCM) that measures this volume of fluid in the patient's peritoneal cavity by segmental bioimpedance spectroscopy (SBIS), to thereby determine an ultrafiltration volume of fluid in the patient's peritoneal cavity, and a switch, controlled by the PCM, for filling the patient's peritoneal cavity and draining the patient's peritoneal cavity when the ultrafiltration volume is unchanged over time, significantly decreased, or decreasing at a significant rate.

Abstract: Systems and methods of disinfection of catheter connections are provided. A transfer catheter connector can include a UV-transparent window at its distal end and a sealing plunger proximal to the UV-transparent window. A solution set connector can be inserted inside a portion of the transfer catheter connector to connect a solution set and transfer catheter. The solution set connector comprises a lumen covered by a leading membrane surface; a sealing surface configured to sealingly engage the window surface, and a piercing member configured to pierce the membrane surface. The sealing plunger, membrane surface, and window define a disinfection zone. The connectors can be connected in a disinfection position configuration in which flow is not permitted between the catheters and the connectors are irradiated with UV light. After disinfection, the connectors are advanced to a flow position in which the piercing member pierces the membrane surface, enabling flow between the catheters.

Abstract: The present disclosure is directed to a robust system and method that delivers precise volumes of fluid, including weight-based fluid volumes (e.g., as prescribed by a medication dose), avoids the expenses and complexity associated with having multiples devices for cutaneous, subcutaneous, and oral administration, avoids the time-consuming cleaning associated with internal component contamination, and avoids the expenses and complications associated with human and mechanical error and failure, of prior art mass fluid delivery systems and methods.

Abstract: A method of removing vascular blockage includes providing a catheter system, comprising an outer catheter, a bypass catheter, and a guidewire. In the catheter system, the bypass catheter is slidably disposed within the outer catheter. The method includes positioning a distal end of the catheter system at a proximal end of an occlusion located within a vessel and moving the bypass catheter through the occlusion so that a medicated treatment solution may be delivered through the bypass catheter to an area of the brain or other tissue served by the vessel blocked by the occlusion. Both during and after the delivery of medicated treatment solution to the blocked part of the vessel with the bypass catheter, the physician may engage the occlusion with the perforated segment of the outer catheter so that a thrombolytic agent can be delivered at the occlusion to disintegrate it and then removing at least a portion of the occlusion from the vessel.

Abstract: A drug delivery system for injecting a medicament includes a housing defining a cavity, a container received within the cavity and configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly received within the cavity and configured to drive the stopper within the container, a needle actuator assembly received within the cavity and comprising a needle configured to be placed in fluid communication with the container, the needle moveable from a first position and a second position spaced from the first position, and a sterilizer received within the cavity and configured to sterilize at least one of the container, the drive assembly, and the needle actuator assembly upon activation of the drug delivery system.

Abstract: A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.