Abstract: A nanocomposite that includes a core containing silver nanoparticles, and a shell that includes polypyrrole and carbon nanotubes, wherein the polypyrrole covers at least a portion of the carbon nanotubes, and wherein the shell covers at least a portion of the core and a method of making the nanocomposite. Various combinations of the nanocomposite, the method of making the nanocomposite, and a method of disinfecting an aqueous solution with the nanocomposite, are also provided.

Abstract: The present invention relates to drug formulations in dry powder form for administration by inhalation and indicated for the treatment of obstructive airway syndromes such as asthma and chronic obstructive pulmonary disease (COPD).

Abstract: Methods and compositions are provided that load and encapsulate an agent, such as a protein, in a porous self-healing polymer. A delivery system includes a porous self-healing polymer, an ionic affinity trap within the pores of the self-healing polymer, and an agent associated with the ionic affinity trap. Methods of encapsulating an agent in a polymer include providing a porous self-healing polymer comprising an ionic affinity trap within the pores. The polymer is incubated with an agent having an affinity for the ionic affinity trap. At least a portion of the pores in the polymer are then healed. Active encapsulation of macromolecules at low concentrations may be achieved due to affinity of the agent for the ionic affinity trap within the pores.

Abstract: A method of regulating a skin conditions that includes applying a safe and effective amount of achachairu to a target portion of skin in need of treatment or where treatment is desired. The achachairu can be in the form of a bioactive ingredient that exhibits anti-inflammatory, anti-oxidant, and/or anti-aging properties, and which is free or substantially free of benzophenones and/or protein. The achachairu ingredient may be a serum fraction and/or an extract, and may be incorporated into a skin care composition formulated for topical use on skin.

Abstract: Embolic materials, suspensions, kits and related methods useful for embolization are disclosed. An embolic material can comprise a resorbable microsphere including cross-linked gelatin as its primary ingredient and having a substantially spherical shape with a diameter of about 50 micrometers to about 1,500 micrometers, inclusive. The microsphere can optionally include one or both of a marker or an active agent. The microsphere can be cross-linked, such as with glutaraldehyde or formaldehyde, which can affect the microsphere's in vivo degradation profile and ability to withstand a sterilization process at certain temperatures. In an embodiment, the microspheres can resorb during an in vivo time period of between about 24 hours and about 15 weeks, inclusive. An embolization suspension can include a plurality of resorbable microspheres and a liquid carrier, and the suspension can be disposed in a syringe, vial or other applicator for administration to a patient.

Abstract: A method of regulating mammalian keratinous tissue that includes applying a safe and effective amount of achachariu to a target portion of keratinous tissue. The achachariu can be in the form of a bioactive ingredient that exhibits anti-inflammatory, anti-oxidant, anti-aging, and/or anti-protein loss properties, and which is free or substantially free of benzophenones and/or protein. The achachariu ingredient may be a serum fraction and/or an extract, and may be incorporated into a personal care composition formulated for topical use on skin and/or hair.

Abstract: Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer.

Abstract: A composition includes from 40 to 80% by weight of at least one non-volatile hydrogenated polyalkylene oil; from 10 to 50% by weight of at least one tertiary-amide-terminated polyamide (ATPA) polymer; and further at least one fatty acid ester having at least one free hydroxyl group, and preferably a hydroxystearate ester. The composition is translucid.

Abstract: An aqueous loxoprofen-containing patch is provided, which has good stability and excellent transdermal absorption of loxoprofen. The aqueous patch includes loxoprofen or a salt thereof and triacetin. Specifically, the aqueous patch includes, based on the weight of the adhesive gel base, 0.1 to 5% by weight of loxoprofen or a salt thereof, 0.5 to 5% by weight of triacetin, 1 to 30% by weight of a water-soluble polymer, 0.01 to 5% by weight of a cross-linking agent, 10 to 90% by weight of purified water, and 0 to 20% by weight of an inorganic powder.

Abstract: The invention concerns a method for straightening keratinous fibers including: (i) a step of applying on the keratinous fibers a hair straightening composition containing at least one cyclic or linear amide, (ii) a step of increasing the temperature of the keratinous fibers, using heating means, to a temperature ranging between 110 and 250° C.

Abstract: The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium: an aqueous phase, spiculisporic acid, at least one non-sulfate and non-sulfonate surfactant, and at least one base, wherein the ratio R1 of number of moles of base over the number of moles of spiculisporic acid is strictly greater than 1.

Abstract: The present application relates to a nondetergent cosmetic composition comprising at least one alkoxysilane comprising at least one basic functional group and at least one microbial gum. The present disclosure also relates to the use, for the treatment of keratin materials, such as the hair, for example, damaged, curly, dry or fine hair, of this composition, and also to a method of hair shaping comprising the application of said composition to the hair.

Abstract: Embolic materials, suspensions, kits and related methods useful for embolization are disclosed. An embolic material can comprise a resorbable microsphere including cross-linked gelatin as its primary ingredient and having a substantially spherical shape with a diameter of about 50 micrometers to about 1,500 micrometers, inclusive. The microsphere can optionally include one or both of a marker or an active agent. The microsphere can be cross-linked, such as with glutaraldehyde or formaldehyde, which can affect the microsphere's in vivo degradation profile and ability to withstand a sterilization process at certain temperatures. In an embodiment, the microspheres can resorb during an in vivo time period of between about 24 hours and about 15 weeks, inclusive. An embolization suspension can include a plurality of resorbable microspheres and a liquid carrier, and the suspension can be disposed in a syringe, vial or other applicator for administration to a patient.

Abstract: The present invention relates generally to cosmetic compositions that impart a matte finish to human integuments. More specifically, the invention relates to lip cosmetics that impart a matte finish.

Abstract: The disclosure provides drug delivery devices and methods of making and using the drug delivery devices. The devices include single and multi-layer polymer films made by a breath figure technique having therapeutic agents associated therewith. For example, the devices may be a dual layer polymer film wherein the first layer includes a therapeutic agent incorporated into it by spin coating the first agent with a polymer solution and the second agent is incorporated into the second layer by loading the agent into pores of the second layer after it is spin coated onto the first layer. In some cases one layer provides a burst release and the second layer provides a slow release drug delivery profile. The devices may take on the form of a surgical mesh with a slow release therapeutic drug.

Abstract: The presently disclosed and/or claimed inventive concept(s) relates generally to the use of nonionic hydrophobically modified polysaccharides in personal care and household care compositions. More specifically, but not by way of limitation, the presently disclosed and/or claimed inventive concept(s) relates to the use of hydrophobically-modified cellulose ethers, such as hydrophobically-modified hydroxyethylcellulose (HMHEC) polymers in personal care and household care compositions. These compositions show pronounced syneresis in aqueous solutions or in the presence of surfactants, including nonionic surfactants and anionic surfactants such as lauryl sulfate (LS) and lauryl ether sulfate (LES). It is also contemplated that the surfactants used in the compositions be sulfate free and/or multi-tailed.

Abstract: A medical device comprises a supporting structure capable of containing or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient may contain one or more therapeutic agents or substances, with the carrier preferably including a coating on the surface thereof, and the coating containing the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. Drugs that are suitable for use in this invention include, but are not limited to drugs of Formula (I).

Abstract: The present disclosure relates to a polymeric system for release of an active agent, comprising a first polymeric phase containing the active agent, the first polymeric phase forming discrete regions of a set size range and being dispersed within a second polymeric phase comprising a cross-linked polymer-phenol conjugate for release of the active agent therein. The present disclosure further provides an injectable hydrogel comprising the disclosed polymeric system, a carrier for delivering a biologically active substance or a drug comprising the injectable hydrogel, and a method for producing the disclosed polymeric system.

Abstract: The invention relates to a cosmetic process for treating keratin fibers, comprising a step of applying, to the keratin fibers, a first cosmetic composition comprising an amino polymer comprising a primary amine group, followed by a step of applying a second cosmetic composition comprising an activated ester of formula R—C(O)OA1 in which R denotes a C5-C21 alkyl group, and A1 denotes a particular reactive group and in particular a succinimide group. The invention also relates to a kit comprising a first cosmetic composition comprising said amino polymer and a second cosmetic composition comprising said activated ester, the first and second compositions each been packaged in a separate packaging assembly. The process gives the treated damaged fiber a long-lasting hydrophobic surface state, the hydrophobicity effect being persistent after one or more shampoo washes, while at the same time affording a good cosmetic feel.

Abstract: The invention pertains to the field of cosmetic and/or dermatological compositions and relates to quick-penetrating skin care compositions for topical application to human skin, containing wax components, carbomers, certain fatty alcohols, emollients, certain fatty acid and fatty alcohol esters, and at least one active ingredient selected from among creatine, allantoin, and/or glycerin. The invention further relates to methods for the production and to uses of such compositions.