Abstract: A cosmetic skin care composition for improving the appearance of aging skin. The composition is topically applied to a target area of skin where treatment is desired. The composition includes an effective amount of artichoke leaf extract and carob fruit extract in combination, and is applied for a period of time sufficient to improve the appearance of the aging skin.
Type:
Grant
Filed:
June 28, 2017
Date of Patent:
October 31, 2017
Assignee:
The Procter & Gamble Company
Inventors:
Rosemarie Osborne, Lisa Ann Mullins, Deborah Ruth Finlay
Abstract: Oral dosage forms containing an opioid antagonist in a sequestered form are described. The opioid antagonist is sequestered such that it is not released or substantially not released in the gastrointestinal tract from the dosage form which is administered orally intact. However, when the dosage form is chewed, crushed, heated or dissolved in a solvent, and then administered orally, intranasally, parenterally or sublingually, the opioid antagonist is released and at least partially blocks effects of the opioid agonist.
Type:
Grant
Filed:
August 24, 2016
Date of Patent:
October 31, 2017
Assignee:
Purdue Pharma L.P.
Inventors:
Benjamin Oshlack, Curtis Wright, J. David Haddox
Abstract: Micro-capsules for the slow release of drugs, consisting of a lactic-co-glycolic copolymer to which a plasticizer has been incorporated and which contain a drug of pharmaceutical interested within them.
Type:
Grant
Filed:
April 23, 2008
Date of Patent:
October 17, 2017
Assignee:
GP PHARM, S.A.
Inventors:
Antonio Parente Dueña, Josep Garcés Garcés, Angel Bonilla Muñoz, David Cunillera Colomé
Abstract: The present invention provides an oral delivery system for a therapeutic compound that is an acid, a salt of an acid or an unionized compound or a proactive form thereof with pharmacological, physiological or biochemical activity. The present invention particularly provides a swallow formulation comprising a therapeutic compound that is an acid, a salt of an acid or an unionized compound or a proactive form thereof which facilitates the rapid delivery of the therapeutic compound to the circulatory system.
Type:
Grant
Filed:
November 28, 2006
Date of Patent:
September 12, 2017
Assignee:
Johnson & Johnson Consumer Inc.
Inventors:
Michael Stephen Roberts, George Alexander Davidson, Ruoying Jiang, Geraldine Ann Elliott, Keivan Bezanehtak, Stephen Douglas Chandler, Greg Davey, Mantu Sarkar
Abstract: This present application relates to microcapsules or compositions containing microcapsules wherein the microcapsules comprise a polymerizable lactamic copolymer. More particularly, certain aspects are directed to the use of polymerizable lactamic copolymers in the formation of coatings on microencapsulated particles. These polymerizable lactamic copolymers can result in surface modified microencapsulated particles that may be anionic, non-ionic, or cationic.
Type:
Grant
Filed:
December 22, 2010
Date of Patent:
September 12, 2017
Assignee:
ISP INVESTMENTS LLC
Inventors:
David K. Hood, Karyn B. Visscher, Surya Kamin
Abstract: The subject of the invention is the use of an extract of Stevia in combination with a salt, for masking the bitterness of bitter compounds in cosmetic or dermatological compositions. This mixture of sweetener with a second gustatory agent makes it possible to mask the bitterness of the compound permanently without changing the nature of the fragrance or the colour of the composition.
Type:
Grant
Filed:
August 31, 2012
Date of Patent:
September 5, 2017
Assignee:
LVMH RECHERCHE
Inventors:
Karine Chevet, Valérie Alard, Eric Perrier, Marie-Laure Souvie
Abstract: The present invention provides pharmaceutical compositions suitable for oral delivery and methods of treating subjects in need thereof. The pharmaceutical compositions of the present invention enhance bioavailability of at least one compound classified as BCS Class II, BCS Class III or BCS Class IV.
Type:
Grant
Filed:
November 16, 2016
Date of Patent:
August 29, 2017
Assignee:
Enteris Biopharma, Inc.
Inventors:
Stephen M. Carl, John Stanley Vrettos, William Stern
Abstract: A stable skin care composition for improving the appearance of aging skin is disclosed. The stable skin care composition that includes an effective amount of artichoke leaf extract and carob fruit extract that, in combination, can provide a synergistic increase in the up-regulation of key epidermal-associated genes related to skin aging, and thereby provide an improvement in the appearance of aging skin. The stable skin care composition excludes complexing agents and includes sunscreen agents to help photostablize the composition.
Type:
Grant
Filed:
October 6, 2016
Date of Patent:
August 8, 2017
Assignee:
The Procter & Gamble Company
Inventors:
Rosemarie Osborne, Lisa Ann Mullins, Deborah Ruth Finlay
Abstract: The present invention provides a transdermal drug delivery system comprising a drug-containing matrix layer comprising: (a) donepezil or a pharmaceutically acceptable salt thereof as an active ingredient; and (b) an acrylate-rubber hybrid as an adhesive.
Abstract: The present invention provides extended release pharmaceutical formulations of valsartan with controlled impurity levels. Particularly, the present invention provides extended release valsartan formulation which is substantially free of valsartan R-isomer impurity.
Type:
Grant
Filed:
March 24, 2016
Date of Patent:
June 27, 2017
Assignees:
Ezra Pharma LLC, Rubicon Research Private Limited
Inventors:
Joseph A. Fix, Shirish A. Shah, Pratibha S. Pilgaonkar, Anilkumar S. Gandhi
Abstract: A solid administration form, protected from parenteral abuse and containing at least one viscosity-increasing agent in addition to one or more active substances that have parenteral abuse potential. The agent forms, when a necessary minimum amount of an aqueous liquid is added, on the basis of an extract obtained from the administration form, a preferably injectable gel that remains visually distinct when introduced into another quantity of an aqueous liquid.
Type:
Grant
Filed:
August 24, 2016
Date of Patent:
June 13, 2017
Assignee:
GRÜNENTHAL GMBH
Inventors:
Johannes Bartholomaeus, Heinrich Kugelmann
Abstract: Methods and compositions are provided for increasing the anaerobic working capacity of muscle and other tissues. Also provided are compositions formulated for the sustained release of free beta-alanine. Also provided is a dietary supplement formulated, for example, as a solid food product, an edible suspension, liquid or semi-liquid as described herein.
Type:
Grant
Filed:
February 19, 2015
Date of Patent:
May 2, 2017
Assignee:
Natural Alternatives International, Inc.
Abstract: The present invention relates to an antimicrobial wound dressing comprising chitosan-silver nanoparticles and a preparation method thereof The antimicrobial wound dressing is prepared by coating a wound dressing with chitosan and silver and drying the coated wound dressing and has an excellent property of releasing silver nanoparticles in a sustained manner.
Type:
Grant
Filed:
December 28, 2012
Date of Patent:
April 4, 2017
Assignee:
CG Bio Co., Ltd.
Inventors:
Hyun Seung Ryu, Jun Kyu Park, Jun Hyuk Seo, Young Koo Lee
Abstract: Provided is a method for increasing hair shaft diameter, the method including applying a hair care composition to a region of the hair, wherein the hair care composition includes from about 1.5% to about 3% resorcinol and from about 0.1% to about 10% of a rheology modifier.
Abstract: Methods and devices are provided for activating brown adipose tissue with targeted substance delivery. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a chemical configured to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly can be delivered to a patient, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The chemical can be delivered to the patient locally and/or systemically to stimulate the nerves and/or the brown adipocytes.
Type:
Grant
Filed:
December 21, 2011
Date of Patent:
April 4, 2017
Assignees:
Ethicon Endo-Surgery, Inc., The General Hospital Corporation
Inventors:
Jason L. Harris, Taylor W. Aronhalt, Dwight Henninger, James W. Voegele, Lee M. Kaplan, Nicholas Stylopoulos
Abstract: Disclosed herein are pH-dependent silk fibroin-based ionomeric compositions and colloids, and methods of making the same. The state of the silk fibroin ionomeric compositions is reversible and can transform from a gel-like colloid to a more fluid-like solution, or vice versa, upon an environmental stimulus, e.g., pH. Thus, the silk-based ionomeric compositions and colloids can be applied in various industries, ranging from electronic applications to biomedical applications, such as sensors, gel diodes, absorbent materials, drug delivery systems, tissue implants and contrast agents.
Abstract: A composition for enteric hard capsules, and an enteric hard capsule prepared using the composition. The composition for enteric hard capsules may include polyol having at least three hydroxyl groups. During the storage of the enteric hard capsule prepared using the composition, the separation of salt from the capsule is delayed.
Type:
Grant
Filed:
February 21, 2011
Date of Patent:
March 28, 2017
Assignee:
LOTTE FINE CHEMICAL CO., LTD.
Inventors:
Jin Ryul Son, Hyon Ho Baek, Eun Hee Park, Sung Wan Lee, Min Gyu Song, Ja Hyun Cha, Jae Uk Cha, Won Hwa Ko
Abstract: An inhibitor of endothelin action or a skin-whitening agent, comprising a compound represented by Formula (1) or a salt thereof as an active ingredient: wherein in Formula (1), R1 represents a formyl group or an alkyl group having 1 to 4 carbon atom(s), and R2 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atom(s).
Abstract: The present disclosure relates to compositions and methods for contraception that also enhance the efficacy of microbicides. Such compositions serve the dual purpose of preventing pregnancy and lessening the risk of spreading sexually transmitted diseases. More specifically, the compositions and methods relate to syngergistic contraceptive microbicide and antiviral compositions comprising a combination of a contraceptive microbicide and an antiviral agent in an acidic carrier that enhances the efficacy of both the contraceptive microbicide and antiviral agent.