Patents Examined by Jianfeng Song
  • Elastomer
    Patent number: 11318084
    Abstract: Provided is an elastomer that improves the skin feel of an inorganic powder. The elastomer according to the present invention is an elastomer comprising: (A) an amino group-containing silicone polymer; and (B) a carboxyl group-containing silicone polymer or a carboxyl group-containing acrylamide polymer, wherein a molar ratio Y/X between amino groups and carboxyl groups is within a range of 0.1 to 1.2, wherein Y denotes the molar amount of carboxyl groups contained in the component (B), and X denotes the molar amount of amino groups contained in the component (A).
    Type: Grant
    Filed: May 29, 2017
    Date of Patent: May 3, 2022
    Assignee: SHISEIDO COMPANY, LTD.
    Inventors: Tomo Osawa, Ayano Matsuo, Yuji Sonoyama, Tomoko Ikeda, Shun Kubota, Mao Hitomi, Takuya Hiruma, Tetsuya Kanemaru
  • Absorbable biomedical composite material and preparation method therefor
    Patent number: 11311651
    Abstract: Provided are an absorbable biomedical composite material and a preparation method therefor. The absorbable biomedical composite material comprises: substrate granules containing a calcium-phosphorus compound; an intermediate layer which is coated on the surface of each of the substrate granules and has a first glass transition temperature, the first glass transition temperature being not higher than normal human body temperature; and a polymer matrix which is formed on the outer surface of the intermediate layer and has a second glass transition temperature, the second glass transition being higher than the first glass transition temperature. The absorbable biomedical composite material has increased mechanical strength and also improved toughness.
    Type: Grant
    Filed: July 15, 2018
    Date of Patent: April 26, 2022
    Assignee: SHENZHEN CORLIBER SCIENTIFIC CO., LTD.
    Inventors: Yang Sun, Feng Pan, Yucheng Huang, Dong Xiang
  • Vaginal inserted estradiol pharmaceutical compositions and methods
    Patent number: 11304959
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: April 19, 2022
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Thorsteinn Thorsteinsson, Peter H. R. Persicaner, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani, Julia Amadio
  • N-acyl sarcosines as antimicrobials for preservation of home and personal care products
    Patent number: 11304886
    Abstract: N-Acyl sarcosines of Formula I, wherein, R?C7 alkyl and C10 alkenyl group with terminal double bond, are described as new antimicrobial preservatives for home and personal care products. Lipidated sarcosines of this patent application preserve creams, lotions, emulsions, solutions or suspensions types of formulations of personal care industry. These are used in: leave-on?? (cold cream, sunscreen) as well as: rinse-off?? (facewash, body wash, shampoo) formulations either alone or in combination with other antimicrobials.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: April 19, 2022
    Assignee: GALAXY SURFACTANTS LTD.
    Inventors: Bhagyesh Jagannath Sawant, Devyani Ashok Mali, Arpit Wankhade, Nirmal Koshti
  • Transdermal therapeutic system on the basis of adhesive plasticizer-polymer matrices
    Patent number: 11304912
    Abstract: The present application relates to a transdermal therapeutic system comprising a backing layer impermeable to active substances and a polymer matrix on one side of the backing layer impermeable to active substances, wherein the polymer matrix comprises at least one pharmaceutically active substance, at least one inherently non-self-adhesive polymer and at least one plasticizer, said polymer matrix being free of adhesive polymers. The invention further relates to a method of producing the transdermal therapeutic system and to the use thereof as a drug.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: April 19, 2022
    Assignee: LTS LOHMANN THERAPIE-SYSTEME AG
    Inventors: Michael Linn, Markus Müller, Marius Bauer
  • Methods for improving respiratory system health and increasing the concentration of hypothiocyanate ion in vertebrate lungs
    Patent number: 11298374
    Abstract: The present disclosure relates to methods and devices to improve respiratory system health, increase resistance to infection, and increase the hypothiocyanate ion in mammalian lungs. The methods generally comprise: generating a Hydrogen Peroxide Gas that is non-hydrated and free of ozone, and directing the gas comprising primarily Hydrogen Peroxide Gas into an environment and exposing a subject to the environment such that the Hydrogen Peroxide Gas acts to the increase of the hypothiocyanate ion in mammalian lungs.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: April 12, 2022
    Inventor: James D. Lee
  • Gelling compositions for treating malignant tumours and/or preventing tumour recurrence
    Patent number: 11291630
    Abstract: The present invention relates to gelling compositions, which changes from liquid state to gel state in function of temperature comprising: at least a poloxamer or mixture of poloxamers; at least a gelling agent; and at least an anticancer agent. Said compositions are advantageously used for local administration of an anticancer agent. Said compositions are useful for size-reduction of a tumour before surgical removal of said tumour, for preventing tumour recurrence after surgical removal of a tumour, and/or treating small tumours. They are therefore useful for the treatment of cancer, preferably a cancer of a wall of the digestive system or a gynaecologic cancer. The present invention also relates to a method for preparing said gelling compositions.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: April 5, 2022
    Inventors: Nathalie Mignet, Vincent Pierre-Marie Boudy, Johanne Seguin, Daniel Scherman, Yoran Beldengrun
  • Agent and method for the temporary shaping of keratinous fibers
    Patent number: 11273106
    Abstract: Cosmetic compositions or agents and methods for the temporary shaping of keratinous fibers are provided. In an embodiment, a cosmetic composition contains from about 2.0 to about 8.0 wt. % hydrophobized metal oxide powder; from about 0.01 to about 2.0 wt. % carbon-based adsorption agent; from about 3.0 to about 35 wt. % lipid; from about 1.0 to about 10 wt. % emulsifier; and from about 30 to about 50 wt. % water. Embodiments include the use of such cosmetic compositions and methods for employing such compositions.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: March 15, 2022
    Assignee: HENKEL AG & CO. KGAA
    Inventors: Nora Koopmann, Anna Puls
  • Vaginal inserted estradiol pharmaceutical compositions and methods
    Patent number: 11241445
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: February 8, 2022
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Thorsteinn Thorsteinsson, Peter H. R. Persicaner, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani, Julia Amadio
  • Ophthalmic emulsion
    Patent number: 11234929
    Abstract: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: February 1, 2022
    Assignee: Alcon Inc.
    Inventors: Howard Allen Ketelson, David L. Meadows
  • Microspheres containing therapeutic agents and related methods of use
    Patent number: 11229604
    Abstract: Microspheres, compositions including the microspheres, and methods of using the microspheres are disclosed herein. The microspheres can be substantially spherical and can include a copolymer of a monomer (such as an acrylic monomer) and a cyclodextrin or a derivative thereof. The microspheres can also include a therapeutic agent, such as a platinum-based drug.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: January 25, 2022
    Assignee: Biosphere Medical, Inc.
    Inventors: Philippe Reb, Meriadeg Thomas
  • Concentrated shampoo dosage of foam for providing hair care benefits
    Patent number: 11202740
    Abstract: Described herein is dosage of foam including from about 5 cm3 to about 70 cm3 of the foam. The foam includes from about 0.5 g to about 4 g of a detersive surfactant; from about 0.001 g to about 4 g propellant; a foam density of from about 0.02 g/cm3 to about 0.25 g/cm3; and a bubble size distribution having an R32 of from about 5 ?m to about 150 ?m.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: December 21, 2021
    Assignee: The Procter and Gamble Company
    Inventors: Jazmin Veronica Torres Rivera, Eric Scott Johnson, Sarah Elizabeth Mullen, Sean Michael Renock, Todd Ryan Thompson, Jean Jianqun Zhao, Robert Wayne Glenn, Jr.
  • Compositions and methods of mechanically inducing tissue regeneration
    Patent number: 11197944
    Abstract: The present invention provides methods and compositions for promoting regeneration of a tissue, methods for preventing or reducing inflammation of a tissue, methods for preventing or reducing fibrosis of a tissue, methods for increasing a mass of a tissue, methods for increasing a level of oxygen available to a tissue, methods for increasing a rate of metabolic waste removal from a tissue, methods for increasing blood perfusion to a tissue, and methods of treating severe muscle tissue damage in a subject in need thereof by contacting the tissue with a composition that is suitable for applying cyclic mechanical compression to the tissue.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: December 14, 2021
    Assignees: President and Fellows of Harvard College, CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN
    Inventors: Christine A. Cezar, Conor J. Walsh, David J. Mooney, Ellen T. Roche, Herman H. Vandenburgh, Georg N. Duda
  • Multi-layered high dosage dissolvable film for oral administration
    Patent number: 11185500
    Abstract: Multilayer dissolvable film suitable for oral administration, as well as method of use thereof and method of manufacturing thereof. The dissolvable film contains multiple (e.g., two or more) layers, configured such that the active ingredient(s) can be present in a total amount of at least about 30 wt. % (e.g., at least about 250 mg). The dissolvable film is mucoadhesive and capable of dissolving within about 60 seconds when placed in the oral cavity.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: November 30, 2021
    Assignee: OAK THERAPEUTICS INC.
    Inventors: Edward Maliski, Zachary Nicolay
  • Implantable medical products, a process for the preparation thereof, and use thereof
    Patent number: 11185616
    Abstract: Implantable medical product, comprising a basic body and an imidazole derivative in the form of its free base; wherein said basic body has on its polymeric surface a layer containing the imidazole derivative as an active ingredient, which displays an antithrombogenic, antiproliferative, anti-inflammatory or antiadhesive effect, or a combination thereof.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: November 30, 2021
    Inventor: Jörg Michael Schierholz
  • Compositions comprising pH-sensitive microcapsules
    Patent number: 11166889
    Abstract: Disclosed herein is a composition comprising a pH-sensitive microcapsule comprising (1) a shell wall comprising at least one polymer chosen from cellulose derivatives and acrylate derivatives, and at least one structuring agent chosen from shellac, ethyl cellulose, and fumed silica, and (2) at least one functional ingredient encapsulated inside the shell wall; and a carrier having a pH of less than about 7. Further disclosed herein are methods of making a composition comprising a pH-sensitive microcapsule.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: November 9, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Evelyn Mohammed, Amjad Farooq, Robert Vogt, Paul Thomson, Yelloji-Rao Mirajkar, Victoria Yeung
  • Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates
    Patent number: 11160829
    Abstract: Novel dinuclear silver(I) pyrazolido complexes and methods of synthesizing them are provided. Advantageously, the novel silver(I) pyrazolido complexes have excellent antimicrobial activity and methods of using said complexes to treat bacterial, fungal, and viral infections are also provided.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: November 2, 2021
    Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Raphael G. Raptis, Indranil Chakraborty, Shambhu Kandel
  • Anti-aging hair treatment
    Patent number: 11154489
    Abstract: A hair strengthening, nourishment, and growth composition and method of application that can be used in the form of a shampoo, conditioner, and a serum.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: October 26, 2021
    Inventor: Nour Kawa
  • Concentrated shampoo dosage of foam designating hair conditioning benefits
    Patent number: 11154467
    Abstract: Described herein is a dosage of foam including from about 5 cm3 to about 70 cm3 of the foam. The foam includes from about 0.5 g to about 4 g of a detersive surfactant; from about 0.001 g to about 4 g propellant, a foam density of from about 0.05 g/cm3 to about 0.35 g/cm3; a bubble size distribution including an R32 of from about 5 ?m to about 100 ?m; and a gloss unit measurement of from about 4 to about 40 GU. The propellant is selected from 1,3,3,3-tetrafluoroprop-1-ene, 1,1 difluoroethane, and mixtures thereof.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: October 26, 2021
    Assignee: The Procter and Gamble Plaza
    Inventors: Sean Michael Renock, Sarah Elizabeth Mullen, Samuel Wolfe Stofel, Jazmin Veronica Torres Rivera, Robert Wayne Glenn, Jr.
  • Skin-tightening composition
    Patent number: 11147752
    Abstract: Skin-tightening compositions for providing a physical tightening effect to the skin and methods for using the same. The compositions may be in the form of an oil-in-water emulsion and include about 0.1 wt. % to about 6 wt. % of sodium silicate; at least 3 wt. % to about 11.5 wt. % of magnesium aluminum silicate; about 1 wt. % to about 15 wt. % of one or more fatty compounds; about 0.1 to about 20 wt. % of one or more nonionic emulsifiers; about 1 to about 25 wt. % of one or more polyols; and about 50 to about 90 wt. % of water, wherein the weight percentages are based on the total weight of the composition. The weight ratio of the sodium silicate to magnesium aluminum silicate is from 0.08 to 1.0 and a total amount of sodium silicate and magnesium aluminum silicate is 3 wt. % to 13 wt. %.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: October 19, 2021
    Assignee: L'OREAL
    Inventors: Mariana Montoya, Angelike Galdi, Susan Halpern, David Chan