Abstract: An ultrasonic probe comprising a housing, a first ultrasonic transducer array, a second ultrasonic transducer array, a first light source, and a second light source. The first ultrasonic transducer array is coupled to the housing and configured to emit a first planar ultrasonic beam in a first direction within a first plane. The second ultrasonic transducer array is coupled to the housing and configured to emit a second planar ultrasonic beam in the first direction within a second plane, which is substantially perpendicular to the first plane. The first light source is coupled to the housing and configured to project a first light line substantially within the first plane. The second light source is coupled to the housing and configured to project a second light line within a third plane, which is substantially perpendicular to the first plane and intersects the second plane at an oblique angle. The first light line intersects and is substantially perpendicular to the second light line.

Abstract: Provided are a physiological signal analysis device and method to detect and analyze physiological information of a subject. The physiological signal analysis device includes a memory device configure to store a wrinkle pattern at a measurement position of a subject as a reference position; a sensor configured to sense the reference position and a physiological signal of the subject at the reference position in response to the stored reference position being within a range of the sensor; and a signal processor configured to process the physiological signal sensed the sensor.

Abstract: In an example, physiological signal(s) are received from physiological sensor(s) configured to measure at least one physiological property of a user. An arousal of at least one characteristic of at least one treatment resistant mood disorder is detected through employment of an estimation method based at least in part on at least one of the physiological signal(s). A value for at least one of a plurality of stimulation parameters is selected based at least in part on at least one of the physiological signal(s). An electric field based at least in part on the arousal is produced. The electric field is configured to stimulate at least a portion of a median nerve of the user transcutaneously. The electric field is based at least in part on at least some of the plurality of stimulation parameters.

Abstract: A location tracking system maps anatomical structures in a first coordinate system, in a fixed position within a medical imaging system, which captures 3D images in a second coordinate system. The 3D images are converted to and stored in a standardized format in a third coordinate system in accordance with a first coordinate transformation. A first 3D image captured by the imaging system is registered with the first coordinate system so as to produce a second coordinate transformation. The first and second coordinate transformations are combined so as to derive a third coordinate transformation between the first and third coordinate systems. A second 3D image of a body of a subject, captured by the imaging system, is processed in order to extract image features in the third coordinate system. The extracted image features are joined with location data captured by the location tracking system by applying the third coordinate transformation.

Abstract: A guidance system and method include a real-time imaging device (121) configured to intra-operatively collect image data of a target region to provide a real-time image. A target determination module (108) is configured to generate an overlay map (111) registered to the real-time image to project morphological feature information on corresponding features in the real-time image of the target region. A medical instrument (122) is provided to perform a procedure on the target region such that the at least one medical instrument is guided to a region suitable for performing an operative task based upon the overlay map.

Abstract: A method and system for generating an enhanced image of a volume of tissue, comprising: emitting acoustic waveforms toward the volume of tissue; detecting acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating a reflection rendering of a region of the volume of tissue; generating at least one of a sound speed map and an attenuation map of the region of the volume of tissue; generating a transfer map derived from a set of sound speed parameter values of the sound speed map and/or a set of acoustic attenuation parameter values of the acoustic attenuation map, the set of sound speed parameter values and the set of acoustic attenuation parameters associated with the set of elements of the region of the volume of tissue; and rendering an enhanced image of the volume of tissue, derived from processing of the reflection rendering with the transfer map.

Abstract: The present invention is directed to a novel target detecting device comprising an excitation transducer generating a low frequency pulses of weakly focused ultrasonic energy and a sensing transducer. The present invention also includes a method of aligning a treatment transducer to a target by mapping the target in situ by sending a low frequency ultrasound signal and receiving reflected signals from the target. These inventions provide a simpler way of determining the location of a target and aligning a treatment transducer without the need to generate and interpret an image and then translate the image back onto the target.

Abstract: A method and a system for acquiring a 3D ultrasound image. The method includes receiving a request to capture a plurality of ultrasound image for a medical test corresponding to a medical condition. The method further includes determining a body part corresponding to the medical test. Further, the method includes identifying an imaging site particular to the medical test. Furthermore, the method includes providing a navigational guidance to the user in real time for positioning a handheld ultrasound device. Subsequently, the user is assisted to capture the plurality of ultrasound image of the imaging site in real time using deep learning. Further, the plurality of ultrasound images of the imaging site is captured. Finally, the method includes converting the plurality of ultrasound image to a 3-Dimensional (3D) ultrasound image in real time.

Abstract: A medical device position guidance system includes a plurality of noninvasive external detector devices communicable with an invasive medical device. A magnetic field is used to gather information about the anatomical size and shape of a subject, such as a human. The medical device position guidance system further uses the magnetic field to obtain information about the positioning of the invasive medical device relative to the subject's anatomy. A method of using the medical device position guidance system is also provided.

Abstract: Systems and methods of predicting future medical events are based on the processing of medical image. The prediction of premature birth and estimation of gestational age based on ultrasound images are presented as illustrative examples. The new abilities to estimate the probability of future medical events, before they otherwise could be predicted, provides new avenues for the development of preventative treatments.

Abstract: Delivery systems, and methods using the same, having an ultrasound viewing window for improved imaging and a needle for ablation treatment of target tissues. In an embodiment, the target tissue is a fibroid within a female's uterus. In an embodiment, the delivery system includes a rigid shaft having a proximal end, a distal end, and an axial passage extending through the rigid shaft. In an embodiment, the axial passage is configured for removably receiving the ultrasound imaging insert having an ultrasound array disposed a distal portion.

Abstract: A guidewire system includes an elongated wire configured for insertion into a luminal space, such as the vasculature, of a body. The wire is conductive and configured to conduct electrical signals. One or more sensors are coupled to a distal section of the wire and configured to send and receive the electrical signals via the wire. The wire through which the one or more sensors are coupled is the only wire through which the one or more sensors send and receive the electrical signals.

Abstract: A first signal is generated with a first light detector in response to an ultrasound signal encountering a first measurement beam. A second signal is generated with a second light detector in response to the ultrasound signal encountering a second measurement beam. The second measurement beam propagates through the sample and the first measurement beam propagates outside the sample.

Abstract: Systems and methods for determining if a wearable photoplethysmography device is correctly positioned in operating to medical signs of a user by using a classifier to determine if a signal is valid or invalid. In some embodiments, in using the classifier to determine in a signal is valid or invalid, a lean method of linear computational complexity and minimal memory complexity is provided for determining at the wearable photoplethysmography device if it is correctly positioned. In some embodiments, in using the classifier minimal computational complexity is used in determining at the wearable photoplethysmography device if it is correctly positioned.

Abstract: An intravascular MRI probe assembly for producing real time, three dimension imagery of an interior of a blood vessel includes a probe has diameter is sufficiently small to fit inside of a blood vessel of a human being. An x coil, a y coil and a pair of z coils is each positioned within the probe for producing a magnetic field to facilitate magnetic resonance imaging of an interior of the blood vessel. A first gradient echo coil, a second gradient coil, a shim coil and a magnet is each positioned within the probe. A conductor is coupled to the probe and the conductor extends away from the second end of the probe. Additionally, the conductor is electrically coupled to a magnetic resonance imaging processor to produce a three dimensional image of the interior of the blood vessel.

Abstract: Various embodiments of the present technology generally relate to identification of tumor location. More specifically, some embodiments of the present technology relate automated tracking of fiducial marker clusters in x-ray images for the real-time identification of tumor location and guidance of radiation therapy beams. Some embodiments use processed CBCT projection images, an automated routine of reconstruction, forward-projection, tracking, and stabilization generated static templates of the marker cluster at arbitrary viewing angles. Breathing data can be incorporated into some embodiments, resulting in dynamic templates dependent on both viewing angle and breathing motion. In some embodiments, marker clusters can be tracked using normalized cross correlations between templates (either static or dynamic) and CBCT projection images.

Abstract: During a sEEG (stereo-electroencephalography) intervention into the skull of a patient, there is requirement to drill a large number of trajectories. Typically, instrument stabilisation platforms and robots for protocols requiring only one or two trajectories are rigidly fixed to the skull using surgical anchor members fixed into the skull around the one or two trajectories. However, because sEEG interventions require a large number of trajectories, an impractical number of surgical anchor members need to be fixed into the skull resulting in patient discomfort. Attachment of an intervention platform to all surgical anchor members is not required at once. Accordingly, it is proposed to search for intersection points of the maximum extent of an intervention platform between at least two trajectory entry points on an object of interest of patient, so that at least one surgical anchor member can be shared when the intersection point is at first and the second trajectories.

Abstract: The present invention provides an apparatus which efficiently perform an examination based on an examination order. The apparatus includes a connection unit configured to be connected to a plurality of measurement units each of which includes a light irradiation unit which irradiates a subject with light and a reception unit which receives an acoustic wave generated from the subject irradiated with the light, a first obtaining unit configured to obtain information on an examination order; a second obtaining unit configured to obtain information on a selected one of the measurement units connected to the connection unit, and a determination unit configured to determine whether the selected measurement unit is suitable for the examination order in accordance with the information on the examination order and the information on the selected measurement unit.

Abstract: An apparatus for emitting a field comprising a core, a conductive winding with a first end, a second end, and an intermediate portion, where the conductive winding surrounds a portion of the core and is wound about a winding axis, a protrusion for aligning the apparatus where the protrusion is parallel with the winding axis, and a conductive connector extending from the conductive winding, wherein the conductive connector is electrically coupled with the conductive winding at the intermediate portion.

Abstract: In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L1 and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In one embodiment, the system further includes an optical element configured to adjust the optical path length of the reference arm, wherein the optical element is in optical communication with the reference arm and wherein the optical element is transmissive or reflective.