Abstract: The present disclosure relates to a dialysis device (1), more particularly a microdialysis device for the sampling of substances from the surface of a body organ. The device is particularly useful in the context of the monitoring of a moving organ, such as a beating heart, as the device comprises attachment means (2) allowing for a flexible and reliable attachment thereto. Furthermore, the microdialysis device provides for an efficient exchange of substances, such as metabolic substances, between the organ and the dialysis fluid through a semi-permeable material forming part of the device. There is also provided a method encompassing the device of the disclosure.

Abstract: A method, including ejecting irrigation fluid from a distal end of a probe so as to irrigate tissue, and receiving, over a period of time, initial signals indicative of respective temperatures of the distal end, from a temperature sensor in the distal end. The method also includes formulating from the initial signals a temperature range between upper and lower temperature thresholds and, when a further signal from the temperature sensor, received subsequent to the period of time, is indicative of a further temperature above the upper temperature threshold, raising an alarm that a bubble is present in the irrigation fluid.

Abstract: An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.

Abstract: Described herein are various embodiments of flexible catheters comprising one or more flexibility regions. In one embodiment, a catheter comprises an elongate body having a proximal segment and a distal segment; a first lumen defined by the elongate body and configured for drainage of a liquid from a bodily region; and a plurality of flexibility regions on or in the distal segment of the elongate body. The plurality of flexibility regions, collectively, is configured to passively bend anteriorly. Further, at least one of the plurality of flexibility regions has a defined percent volume of material removed and a defined cut depth percentage. The features and arrangement of the flexibility regions described herein result in the catheter requiring reduced force during insertion into a bodily lumen.

Abstract: Manifolds and methods of operating manifolds are provided. An example manifold for controlling multi-lumen devices is provided that includes a substance supply mechanism. The substance supply mechanism independently provides a substance to, or remove a substance from, each of a plurality of lumens. The example manifold also includes a lumen selection mechanism. The lumen selection mechanism selectively opens and closes a connection between the substance supply mechanism and at least one of the plurality of lumens. A corresponding method of operation is also provided. An example embodiment also includes a manifold for use with a vessel seclusion device.

Abstract: An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device can be a wearable automatic injector configured to be worn on the patient's skin. The delivery device of the present disclosure may allow a user or the patient to view a status of a container. For example, the delivery device of the present disclosure may provide a simple and effective visual means of displaying fill confirmation and delivery confirmation.

Abstract: In some examples, a catheter comprises an inner liner, an outer jacket, and a structural support member positioned between at least a portion of the inner liner and the outer jacket. The inner liner, the outer jacket, and the structural support member define a catheter body that comprises a proximal portion having a first outer diameter, a distal portion having a second outer diameter less than the first outer diameter, the distal portion including a distal end of the catheter body, and a medial portion positioned between the proximal portion and the distal portion, the medial portion tapering from the first outer diameter to the second outer diameter.

Abstract: Apparatus for delivery of bone includes a syringe body and a plunger. The syringe body includes a tip at a bottom thereof, a funnel-shaped top at the top thereof, and a tubular section having a generally cylindrical interior wall defining a passageway extending from the funnel-shaped top to the tip. The plunger includes an elongate piston, a press head, and a handle. The piston extends between the press head at a lower end of the plunger, and the handle at an upper end of the plunger. The plunger is removably received within the passageway, with an extent of the plunger extending out of the funnel-shaped top away from the syringe body. The syringe body may be loaded with one or more bone pellets or cartridges containing bone.

Abstract: An arrangement for delivery of a substance to an animal and a method of protection of a winged capsule. The arrangement may include a winged capsule including a capsule and wings, the capsule being adapted to deliver the substance to the animal, and the wings affixed to the capsule and operable to fold for insertion into the animal and to expand after insertion. The arrangement may include a wing protector including a slot sized and configured to receive at least a portion of each of the wings and removably attach the winged capsule to the wing protector. The method may include removably attaching the winged capsule to the wing protector to form a protected winged capsule; inserting a plurality of the protected winged capsule into a bag; removing one of the protected winged capsule from the bag; and removing the wing protector from the protected winged capsule.

Abstract: An apparatus including a housing, an electrical conductor, and a suction control valve. The housing forms a handle and a shaft. The housing defines a suction channel from a distal end of the shaft. The electrical conductor extends to the distal end of the shaft. The suction control valve is connected to the suction channel at the handle. The suction control valve includes a valve body having a first channel and a second channel connected to the first channel, where the first channel forms a portion of the suction channel; and a valve barrel rotatably connected to the valve body. The valve barrel includes a rotatable ring extending around the handle and forming a portion of the housing. The ring includes an orifice configured to be rotated into and out of registration with an end of the second channel as the ring is rotated about the valve body.

Abstract: Provided is a method of cleaning a body cavity using a device by coupling a distal end portion of a first cannula to the housing such that a lumen is in fluid communication with the first portion of the inner volume, the first cannula coupled to a vacuum source, then coupling a distal end portion of a second cannula to the housing such that a lumen is in fluid communication with the second portion of the inner volume, the second cannula being coupled to a fluid source, inserting a portion of the housing into a body cavity, conveying a fluid from the fluid source to the body cavity via the lumen of the second cannula, and withdrawing the fluid from the body cavity into the vacuum source concurrently with the conveying the fluid, via the lumen of at least the first cannula.

Abstract: Apparatuses and methods for delivering a fluid, including a viscous fluid. These apparatuses may include a fluid reservoir, two or more piston chambers, a manifold, a delivery port, and a drive assembly and may be configured to inject either a predetermined amount of fluid or a continuous stream of fluid. These apparatuses may also be configured to switch between filling, injection and aspiration modes. These apparatuses may generally be hand-held and lightweight and may provide a significant mechanical advantage to the user.

Abstract: Described is a priming device to prime a gas from a fluid delivery system by receiving the gas and a fluid used to push the gas into a chamber, the priming device including a housing having a chamber, an inlet port, and an opening to release gas received into the chamber. The device further includes a sleeve having an open first end for coupling with a male luer connector, a second end coupled to the housing, and an axis between the first and second ends. The sleeve defines at least one window. The device further includes an arm extending from a bottom of each window toward the first end, and a member extending radially from an inner surface of each arm. Each member has a ramp surface, an engagement surface extending transversely to the ramp surface, and an apex area that transitions between the ramp surface and the engagement surface.

Abstract: Apparatuses and methods for delivering a fluid, including a viscous fluid. These apparatuses may include a fluid reservoir, two or more piston chambers, a manifold, a delivery port, and a drive assembly and may be configured to inject either a predetermined amount of fluid or a continuous stream of fluid. These apparatuses may also be configured to switch between filling, injection and aspiration modes. These apparatuses may generally be hand-held and lightweight and may provide a significant mechanical advantage to the user.

Abstract: A system for strain relieving intravenous (IV) assembly includes a dressing and an anchor portion for use with the dressing. In various embodiments, the dressing may cover an injection site into a portion of a patient's body for an intravenous (IV) assembly that provides fluid communication between the injection site and a fluid reservoir remote from the injection site through a flexible tube. In an illustrative example, the anchor portion may include a first member and a second member. The first member may be secured, for example, to the dressing and may, in some examples, wrap around the tubing so as to resist axial movement of the tubing relative to the dressing. The second member may be secured to the dressing and may wrap around the tubing and a portion of the patient's body so as to resist radial movement of the tubing relative to the body.

Abstract: A medical device including a handle body having a proximal end and a distal end, a spool on the handle body and to move between the distal end and the proximal end of the handle body, a catheter extending from the distal end of the handle body, an actuator attached to the spool and extending through the catheter, such that the actuator is removably connected to one or more dispensable devices at a distal end of the catheter, a spool controller to prevent connection with another of the dispensable devices to the actuator after a predetermined number of dispensable devices have been dispensed by the medical device.

Abstract: An infusion pump apparatus includes a length of resilient tubing removably loadable in an infusion pump having a housing, a pumping mechanism, and a pump door. A latch member is pivotally mounted to the pump door and cooperates with a latch pin fixed on pump housing. A free-flow protection device is biased to pinch the tubing closed to stop fluid flow. The latch member has a first range of pivotal motion in a latching direction for causing the latch member to engage with the latch pin to secure the door in a closed position and a second range of pivotal motion in the latching direction for causing the latch member to actuate the free-flow protection device to unpinch the tubing and allow flow. The latch member pivots through at least a portion of the first range of pivotal motion before beginning to pivot through the second range of pivotal motion.

Abstract: A medical device may include an insertion portion longitudinally extending between a proximal end and a distal end. The insertion portion may define a channel extending therethrough. The medical device may further include a handle coupled to the proximal end of the insertion portion. The handle may further include an irrigation port in fluid communication with the channel and coupled to a source of irrigation fluid. Additionally, the handle may include an actuator and a pressurizer. Manipulation of the actuator may be configured to actuate the pressurizer to urge irrigation fluid distally through the channel.

Abstract: Catheters for percutaneous applications are disclosed. The catheter according to example embodiments may comprise a substantially straight section, an anchoring section positioned proximal to the substantially straight section. The anchoring section can have a curvature for providing longitudinal traction with a tissue to anchor the catheter to the tissue and a pathway extending through the catheter for transporting fluids. The pathway may comprise a first section and a second section in fluid communication with each other, where the first section extends through the length of the straight section, and the second section extends through the anchoring section and has a curvature which mimics the curvature of the anchoring section.

Abstract: A system to detect occlusion of an intravenous catheter may include a housing, which may include a distal end configured to couple to a proximal end of a catheter adapter and an inner lumen forming a fluid pathway. The system may also include a wave transmitter, a transducer disposed within the fluid pathway, a processor coupled to the transducer, and an indicator unit coupled to the processor. The wave transmitter may transmit energy waves along a length of an intravenous catheter of the catheter adapter. The processor may receive an electrical signal corresponding to the portion of the energy waves that are reflected back from the intravenous catheter and may determine a difference between the electrical signal and a baseline signal. In response to the difference between the electrical signal and the baseline signal meeting a threshold value, the indicator unit may alert a user.