Abstract: A sample concentrating unit and a sample concentrating method are described, which enable fast, precise and reproducible analyte concentration in a sample by evaporation of sample solvent. A specifically directed gas stream in cooperation with a vacuum generated in the sample concentrating unit keeps the sample at boiling point during the entire evaporation procedure while reducing analyte loss and risk of cross-contamination. The fully automated sample concentrating unit is designed to be integrated into an in-vitro diagnostic analyzer.

Abstract: A reagent cartridge according to an embodiment includes a housing part, a tubular member, and a dispense part. The housing part houses therein a reagent. The tubular member is filled with the reagent housed in the housing part. The dispense part dispenses the reagent supplied from the tubular member. The tubular member has elasticity, and supplies the reagent to the dispense part when a side face part thereof is compressed.

Abstract: The present disclosure relates to blood sample preparation devices and methods. In some embodiments, a method for preparing a blood sample comprises: receiving at a sample preparation machine a sample container containing the blood sample; scanning an identifier of the sample container, the identifier containing information indicative of a characteristic of at least one of the sample container or the blood sample contained therein, actuating, after the scanning, and based on the information, the sample container to repeatedly change a position of the sample container; determining, based on the information, whether the sample container should be centrifuged; and transporting the sample container to a centrifuge to be centrifuged and then to a storage compartment when the determining indicates that the sample container should be centrifuged, and to the storage compartment without entering the centrifuge when the determining indicates that the sample container should not be centrifuged.

Abstract: In this invention, there are cleaning positions 25a, 25b, and 25c where cleaning tanks 19, 20, and 21 discharge cleaning water onto the surfaces of nozzles 10, 12, and 14 and drying positions 26a, 26b, and 26c where the cleaning water adhered to the surfaces of the nozzles 10, 12, and 14 is sucked up. During movement from the cleaning positions 25a, 25b, and 25c for the nozzles 10, 12, and 14 to the drying positions 26a, 26b, and 26c for the nozzles 10, 12, and 14, a control device 24 causes system water to be discharged from the nozzles 10, 12, and 14 for a first time, and during the sucking up of the cleaning water on the surfaces of the nozzles 10, 12, and 14 at the drying positions 26a, 26b, and 26c, the control device 24 causes the system water to be discharged from the nozzles 10, 12, and 14 for a second time. As a result, it is possible to effectively remove adhered water drops during nozzle cleaning.

Abstract: The device is composed of at least one disposable biosensor (2) for applying a blood sample, as well as evaluation electronics (1) for retrieving and processing information from the disposable biosensor (2) with the applied blood sample, as well as a display (7) for displaying information from the evaluation electronics (1). Disposable biosensors (2) and a display (7) are arranged in a common vapour non-permeable closable space, wherein the display (7) is hygroscopic to bind air moisture which would otherwise be bound by disposable biosensors (2). The display (7), evaluation electronics (1) and disposable biosensors (2) can be arranged on a common support substrate (4), wherein the support substrate (4) is provided with a removable and/or openable vapour non-permeable container. Disposable biosensors (2) can be detachable from the support substrate (4).

Abstract: Devices and methods are provided that utilize two adjacent nanopore readers for sequencing of a polymer or a portion thereof.

Abstract: A sample measuring apparatus, a reagent container, and a method of measuring a sample are provided. The sample measuring apparatus includes a reagent container holder and a measuring unit. The reagent container holder holds, by suspending, a reagent container that stores a reagent. The measuring unit that measures a sample by using the reagent.

Abstract: The present invention is one for achieving an improvement in analysis accuracy, and a sample analyzing device that measures light emitted by introducing a reagent to a sample contained in a container to analyze the sample, and the sample analyzing device includes: a holder that holds the container; a casing that has a door for taking in/out the holder; a nozzle to/from which a pipette tip for injecting the reagent into the container can be attached/detached; a photodetector that measures the light emitted from the sample in the container supported by the holder; and a disposal box into which the pipette tip after injection is disposed of, in which the disposal box is configured to be arranged in the casing and to be taken in/out via the door.

Abstract: Provided are a method for preparing a microfluidic device, a microfluidic device and a microfluidic system. The method includes: providing a mold having a groove; injecting a liquid metal into the groove of the mold, and solidifying the liquid metal to obtain a solid metal; separating the solid metal from the mold; providing the solid metal with an electrode; providing a cladding layer on a surface of the solid metal provided with the electrode, such that the solid metal is wrapped by the cladding layer, and at least a part of the electrode extends outside the cladding layer, so as to obtain a preform; and fixing the preform in a substrate, melting the solid metal and extending at least a part of the electrode outside the substrate, to obtain the microfluidic device.

Abstract: Described herein are systems and methods used for washing needle assemblies with multiple needles.

Abstract: The present invention describes a secondary tube tray for use in an automated processing system, the tray comprising a base module and a secondary tube insert. Furthermore, the present invention describes a secondary tube handling module of an automated processing system for automatically processing biological sample, and a method of handling secondary tubes for use in automatically processing biological sample in an automated processing system.

Abstract: A jig assembly for connecting first and second consoles with predefined relative positioning includes first and second positioning pins attached or attachable to the first console and a positioning connection bracket attached or attachable to the second console and including a longitudinal span and first and second transverse legs including first and second pin recesses at respective free ends thereof. The first and second pin recesses receive the first and second positioning pins, respectively, when the first and second consoles are moved laterally toward each other. The first and second transverse legs may be attached to the first console with a first and second leg attachment brackets, respectively. The first and second positing pins and the first and second leg attachment brackets may be fixed with respect to the first console by attachment to a mounting rail that is fixed to the first console.

Abstract: Aspects of the present disclosure are directed to a method and a device for carrying out chemical, biochemical and/or immunochemical analyses of liquid samples, which are present in a sample store of an automatic analyzer, with the aid of liquid reagents, which are present in at least one reagent store of the analyzer. In one embodiment, a analyzer is disclosed including cuvettes for holding the liquid samples and reagents, the cuvettes are arranged in at least one stationary, linear cuvette array. The analyzer further has an optical measurement unit with a stationary light-supplying unit which has at least one light distributor device that feeds the light from a plurality of LED light sources emitting in a spectrally different manner in the UV/VIS/NIR wavelength range into the inlet windows of the individual cuvettes of the cuvette array. The optical measurement unit further includes a stationary detection unit assigned to outlet windows of the cuvettes and further includes a plurality of photodiodes.

Abstract: Systems and methods applicable, for instance, to pipette robots. A pipette robot can perform one or more tip presence check operations, one or more tip seal check operations, and/or one or more distance sensing operations, including distance sensing operations which regard determining the height of the surface of a liquid.

Abstract: Described is a lateral flow high throughput assay device analyzer for preparing and analyzing a plurality of lateral flow assay samples. The analyzer comprises a cartridge stage for supporting an assay cartridge, an elevation adjustment mechanism, and a translation adjustment mechanism for aligning the cartridge stage and assay cartridge relative to a vertical support structure, fluid metering device, and detection device for high throughput lateral flow assay analysis.

Abstract: Disclosed is a sample measurement device comprising a first processing unit that performs a first measurement on a sample contained in a first container in a first cycle; a second processing unit that performs a second measurement on a sample contained in a second container in a second cycle different from the first cycle; and a relay section which is disposed between the first processing unit and the second processing unit and in which the second container is positioned, wherein the first processing unit performs a transferring operation of transferring the second container to the relay section, and the second processing unit performs a receiving operation of receiving the second container that has been transferred to the relay section from the relay section.

Abstract: Systems and methods for conducting surface-mediated chemical and/or biochemical reactions within an enclosed chamber are disclosed. Systems and methods of the present disclosure may be used in conducting hybridization reactions of biopolymers. In some examples, an improved method for mixing thin films of solutions in a hybridization chamber includes altering the direction of mixing at least once over the course of a reaction. In some examples, an improved method for mixing thin films of solutions in a hybridization chamber includes altering the speed of mixing at least once over the course of a reaction. In some examples, an improved method for mixing thin films of solutions in a hybridization chamber includes altering the speed of mixing and the direction of mixing at least once over the course of a reaction.

Abstract: The present invention provides a system for performing reactions, where the system comprises a plurality of synthesisers that are in communication via a communal reporting platform. A synthesiser is programmed for the automated synthesis of one or more chemical or biological reactions, and the synthesiser comprises a reaction vessel which is supplied by a reagent delivery system, an analytical system for analysing a reaction, and a controller for managing the reagent delivery system and the analytical system, and for communication with the reporting platform. Also provided are methods for performing a plurality or reactions using the system.

Abstract: A saliva detection device, a saliva detection system and an operation method of the same are provided. The saliva detection device includes a flexible friction power generation assembly configured to supply power to the saliva detection device and including: a first electrode; a first macromolecule polymer layer which is disposed in contact with a surface of the first electrode and has a concave-convex structure on a surface thereof distal to the first electrode; a second macromolecule polymer layer having a concavo-convex structure on a surface thereof proximal to the first macromolecule polymer layer and a second electrode disposed in contact with a surface of the second macromolecule polymer layer distal to the concavo-convex structure thereof, in response to flexible deformation of the flexible friction power generation assembly, the concavo-convex structures of the first macromolecule polymer layer and the second macromolecule polymer layer rub against each other.

Abstract: An automatic analysis device and an automatic analysis system capable of executing separate operations by respective analysis units even in a device configuration where a same control part controls two or more analysis units, the automatic analysis device including a biochemistry analysis unit; an electrolyte analysis unit; one analysis unit control CPU for controlling operations of the biochemistry analysis unit and the electrolyte analysis unit; and a storage part for storing time charts of operations having different purposes for the biochemistry analysis unit and the electrolyte analysis units. Two or more of the biochemistry analysis units and the electrolyte analysis units operate independently to each other based on the time charts stored in the storage part.