Patents Examined by John McGuirk
  • Patent number: 11511279
    Abstract: A method to handle tubes in a diagnostic laboratory automation system comprising a control device and a tube-analyzing device is presented. The tube-analyzing device comprises a tube identification reader, a tube type recognition unit, a sample color determination unit, and a tube consistence unit. The tube identification reader reads tube identification device. The tube type recognition unit identifies tube type. The sample color determination unit determines sample color. The tube consistence unit determines sample consistency. The sample tube type, the tube type, the sample color, the sample consistency are send to the control device. The control device determines a construed tube type from one or more of the information of the tube type, the sample color, and the sample consistency. The control device checks whether the tube type matches the construed tube type and changes a used tube type from the tube type to the construed tube type.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: November 29, 2022
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Robert Enck
  • Patent number: 11504753
    Abstract: A cleaning module, a sample analyzer with the cleaning module and a cleaning method. Wherein, the cleaning module may include a disk body assembly and a cleaning assembly. The disk body assembly may include a disk body, the cleaning assembly and the disk body may move relatively, and the disk body and the cleaning assembly complete extraction of waste fluid and cleaning on a path of moving relatively.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 22, 2022
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Shuai Tong, Wanguan Yi, Li Yin, Yi Hu, Dingping Ban
  • Patent number: 11498076
    Abstract: Methods of pre-heating a test vessel prior to transfer of the test vessel to an incubator may shorten an incubation cycle, ensure proper temperature of a test specimen in the test vessel, and/or improve testing accuracy and/or throughput in a bio-liquid specimen testing apparatus. The methods include providing a test vessel pre-heating apparatus having a receptacle sized to receive a test vessel therein and having at least one heating unit configured to heat by direct conduction at least one side of the test vessel. The methods also include heating at least one side of the test vessel via direct contact using the at least one heating unit. Specimen testing apparatus and test vessel pre-heating apparatus configured to carry out the method are described, as are other aspects.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 15, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Paul Dulaff, Christopher Delametter
  • Patent number: 11486887
    Abstract: The present invention is provided with a sample rack insertion unit 12 that is capable of holding one or more sample racks 5 having mounted therein one or more sample containers 6 accommodating a sample to be analyzed, one or more analysis devices 2, 3 for analyzing the sample accommodated in the sample containers 6, a sample rack conveyance unit 14 for conveying the sample racks 5 from the sample rack insertion unit 12 to the analysis devices 2, 3, and a control device 4 for acquiring, for each analysis device 2, 3, load information that is information expressing an operating condition of the analysis device 2, 3, and, if there is an analysis device 2, 3 for which the load information is larger than a predetermined conveyance permission value, carrying out control so as to stop the conveyance of the sample racks 5 from the sample rack insertion unit 12 to the analysis device(s) 2, 3.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: November 1, 2022
    Assignee: Hitachi High-Tech Corporation
    Inventors: Masashi Akutsu, Akihisa Makino, Hiroyuki Mishima, Akihiro Yasui
  • Patent number: 11486886
    Abstract: An automatic analyzer includes: a diluted sample holding unit configured to hold dilution containers into which a diluted sample is dispensed; a reaction container holding unit configured to hold reaction containers; a dispensing device configured to dispense the diluted sample from the dilution containers to the reaction containers; a measuring unit configured to perform optical measurement of the diluted sample reacted with reagents corresponding to test items in the reaction containers; a storage unit configured to store information on the diluted sample associated with each of the dilution containers; and a dispensing control unit. The dispensing control unit extracts a dilution container for collecting the diluted sample for retest by searching for the information on the diluted sample stored in the storage unit, and causes the dispensing device to perform a retest dispensing process.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: November 1, 2022
    Assignee: JEOL Ltd.
    Inventor: Toru Ogawa
  • Patent number: 11480526
    Abstract: A sample of water is tested for silica and phosphate content in a single apparatus. In the test method, a first sample of the water is colorimetrically analyzed in a reaction chamber using a “molybdenum blue” test in which silica and phosphate in the sample are complexed with a first reagent. The phosphate complexes are then optically inactivated by a second reagent and the color of the silica complexes is intensified with a third reagent. From this, the silica content is calculated. A further sample is colorimetrically analyzed without using the second reagent, so that a combined silica and phosphate content of the further sample is obtained. A value of the silica content is subtracted from the value of the combined silica and phosphate content, resulting in a phosphate content for the sample. The silica content and the phosphate content of the sample are reportable.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: October 25, 2022
    Assignee: Mettler-Toledo Thornton, Inc.
    Inventors: Robert Theriault, David Marsh, Anthony C. Bevilacqua, Jr.
  • Patent number: 11467175
    Abstract: An analysis device employs an analysis kit including a chip provided with a capillary through which a sample flows and a cartridge superimposed on the chip and provided with a liquid reservoir. The analysis device includes a guide-in section into which the analysis kit is guided, a placement section on which the analysis kit placed so as to be supported, a pusher member that pushes the analysis kit from one side face of the analysis kit, contact members that oppose another side face on an opposite side in the horizontal direction to the one side face of the analysis kit placed on the placement section, and contact the other side face of the analysis kit being pushed in by the pusher member so as to position the analysis kit in the horizontal direction, and a measurement member that measures a component present in the sample in the analysis kit.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: October 11, 2022
    Assignee: ARKRAY, Inc.
    Inventors: Akihiro Yamamoto, Shigeru Kitamura, Naoto Shichi
  • Patent number: 11467173
    Abstract: The sample container loading or storing unit includes a sample rack tray and a sample rack tray installation portion on which the sample rack tray is installed, the sample rack tray installation portion includes a claw portion that moves in a contact direction with a sidewall portion of the sample rack tray, the sample rack tray includes a claw guard portion provided on the sidewall portion of the sample rack tray, and the claw guard portion is configured to be separated from the sidewall portion of the sample rack tray by being pushed by a sample rack.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: October 11, 2022
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Masashi Endo, Katsuhiro Kambara, Shigeru Yano
  • Patent number: 11426736
    Abstract: Disclosed is a gripping device for a container intended for a biological analysis, including an annular part of X axis, elastically deformable gripping fins extending radially inwardly from the annular part, the fins being capable of being deformed when a container is introduced into the annular part, the fins being evenly distributed over the circumference. Each fin has a so-called upper surface and an opposite so-called lower surface, the lower surface being intended to come into contact with the container, the lower surface having a concave zone, or vice versa.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: August 30, 2022
    Assignee: DIAGNOSTICA STAGO
    Inventor: Fabrice Lejay
  • Patent number: 11421272
    Abstract: Disclosed are a positioning method, a positioning apparatus and a sequencing system (300). The sequencing system (300) comprises an imaging assembly (110) and a mobile platform (102), wherein the imaging assembly (110) comprises an optical axis (OP), the mobile platform (102) bears a reaction apparatus (200), the stroke of the mobile platform (102) in a first direction is controlled by means of a limiting switch, and the stroke comprises a first limit.
    Type: Grant
    Filed: September 29, 2019
    Date of Patent: August 23, 2022
    Assignee: GeneMind Biosciences Company Limited
    Inventors: Ruitao Sun, Songzhen Zhang, Zefei Jiang, Zhiliang Zhou, Qin Yan
  • Patent number: 11413621
    Abstract: A disposable test card configured to accept a fluid sample for an assay, and a method of manufacturing same, is disclosed herein. In a general example embodiment, a test card for analysing a fluid sample includes a first substrate layer including an inlet port and an outlet port, a channel layer bonded to the first substrate layer, the channel layer including a microchannel placing the inlet port in fluid communication with the outlet port, and a second substrate layer bonded to the channel layer, the second substrate layer having electrodes printed adjacent to a target zone of the microchannel of the channel layer, wherein the electrodes are configured to raise the temperature of the fluid sample within the target zone of the microchannel when a current is applied thereto.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: August 16, 2022
    Assignee: FLUXERGY, INC.
    Inventors: Ryan Alan Revilla, Roy James Heltsley, Steve Hoe Lee, Tej Rushikesh Patel
  • Patent number: 11415587
    Abstract: It is possible to realize a sample container transfer device capable of handling a plurality of racks in which a sample container can be efficiently transferred from a preprocessing system to a carrier used in an analysis system and can be transferred to a plurality of kinds of carriers of the analysis system. A plurality of kinds of racks A and racks B is held by an empty rack holding area 330. The racks A or the racks B can be used for conveyance of specimen containers according to the application of a specimen. After a fixed number of specimen containers separated by a separation mechanism 301 according to an application are collected by stoppers 303a and 303b, the specimen containers are conveyed to a transfer start position 309 to be transferred from a holder to a rack. Accordingly, it is possible to suppress an occurrence of a state in which the rack does not have a part where no specimen is mounted.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: August 16, 2022
    Assignee: Hitachi High-Tech Corporation
    Inventors: Taro Umeki, Kouji Kamoshida, Masahito Kakuno
  • Patent number: 11406981
    Abstract: Automated test instruments electronically determine and/or obtain cell availability of cells of a holding structure in an incubated test chamber and for each of a plurality of open and available cells and electronically identify neighboring cells, electronically determining whether each of the identified neighboring cells are occupied or empty and, if occupied, electronically evaluating at least one of a test status or a time from load of a specimen container held therein. The instruments then electronically rank each of the plurality of open and available cells based at least in part on whether the identified neighboring cells are occupied or empty and the at least one of test status or time from load of the occupied cells of the identified neighboring cells. The loading mechanism is then directed to load an incoming specimen container into a selected one of the open and available cells based on the ranking.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: August 9, 2022
    Assignee: BIOMERIEUX, INC.
    Inventors: Michael Edmiston, Jonathan Elenkiwich, Warren Vincent
  • Patent number: 11408902
    Abstract: A method to store sample tubes in a laboratory storage and retrieval system is presented. The laboratory storage and retrieval system comprises a storage section, a database comprising a sample tube inventory of the storage section, a control device, and at least one sample tube transport system. The storage section comprises at least two storage subsections. In a first step of the method, the control device identifies at least two sample tubes with at least one substantially identical sample tube attribute and distributed over the at least two storage subsections. In a second step of the method, the at least one sample tube transport system consolidates the at least two sample tubes in at least one storage subsection, wherein the control device further determines in which of the at least two storage subsections the identified sample tubes are consolidated.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: August 9, 2022
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Stefan Waldburger
  • Patent number: 11400460
    Abstract: A solid-core ring-magnet having one or more cavities is provided. The magnet can have an overall cylindrical shape or a rectangular-prism shape. In either case, a portion of cavity walls of the magnet are ring shaped, causing the magnetic field lines to emanate from the magnet in the shape of a ring. The diameter of the ring shaped cavities can be constant throughout, constant through a portion of the cavity, variant throughout, or variant through a portion of the cavity. The cavities open to the end of the magnet, and terminate toward the core of the magnet. Also provided are systems and kits having solid-core ring-magnets. Methods of purifying a macromolecule using the solid-core ring-magnets are also provided.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: August 2, 2022
    Assignee: Alpaqua Engineering, LLC
    Inventor: Olaf Stelling
  • Patent number: 11385224
    Abstract: Systems and methods for use in an in vitro diagnostics setting incorporating magnetic shielding to reduce exposure of any of samples, reactants, devices or people from exposure or prolonged exposure to magnetic or electromagnetic fields generated with the system. Some embodiments provide an automation system for use in an in vitro diagnostics setting comprising an automation track having a sidewall provided with magnetic shielding. In some embodiments, the magnetic shielding comprises an 80% nickel alloy.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: July 12, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Kung-Le Chang, Manuel Lavin, Baris Yagci
  • Patent number: 11385250
    Abstract: An automated analyzer system for biological samples is provided and includes a sample processing system and a controller configured to receive a selection of one of multiple workflows for determining a presence and/or concentration of an analyte in a biological sample and prompt the automated analyzer system to automatically carry out the selected workflow using the sample processing system and output a result classifying the biological sample.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: July 12, 2022
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Barbara Upmeier, Andreas Woeste, Vanessa Balassa
  • Patent number: 11372012
    Abstract: A dispensing robot of an assay robot system includes a first contact surface oriented in a downward direction or an obliquely downward direction in a vertical direction and dispenses when the dispensing robot operates a pipette that allows a tip to be attached to a lower end of the pipette and the attached tip to be detached by pressing a tip ejector, the dispensing robot comprising: a robot arm having a hand to hold a pipette holding piece attached thereto; and a controller controls the robot arm such that the robot arm holds the pipette with the tip attached thereto by causing the hand to hold the pipette holding piece and that the robot arm is elevated and the tip ejector is pressed by bringing an upper end portion of the tip ejector of the held pipette into contact with the first contact surface from the downward direction.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 28, 2022
    Assignees: KAWASAKI JUKOGYO KABUSHIKI KAISHA, SYSMEX CORPORATION
    Inventors: Yukio Iwasaki, Satoshi Ouchi, Eiji Mitsui, Junichi Matsuoka, Hiroya Kirimura, Yukihiko Kitano
  • Patent number: 11366128
    Abstract: A biological analysis system comprising at least one inlet and one outlet, at least two biological analysis devices connected to one another by a conveyor defining a closed circuit, each biological analysis device comprising a region for the exchange of tube holding racks with the conveyor. The conveyor and the at least one inlet of the biological analysis system comprise a reader of an identifier of a tube holding rack which reader is designed to communicate an identifier it has read to a controller of the biological analysis system, which controller is designed to apply a specific treatment to a tube holding rack identified by the reader of the conveyor and the identifier of which has not previously been read by the reader of the at least one inlet of the biological analysis system.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: June 21, 2022
    Assignee: HORIBA ABX SAS
    Inventors: Florent Beauducel, Philippe Benezeth, Thibault Cres
  • Patent number: 11366131
    Abstract: Embodiments are directed to transferring and opening reagent containers for use in a clinical analyzer in an in vitro diagnostics (IVD) environment. Contents of a reagent container may be automatically recorded, and the container is positioned and opened, making available its contents to a transfer probe. A set of mechanical fingers open and close relative to one another, to release and grip the reagent container on opposite sides thereof for transferring the container. Once the container is positioned, the mechanical fingers raise and are positioned above a seal concealing the contents of the reagent container. The fingers are configured to close together and travel in a downward trajectory to pierce the seal. The reagent container is originally presented as an un-opened package to prevent spillage and to control reagent life expectancy. According to an embodiment, a method of performing a cycle unload, transfer, and load, without operator intervention, is provided.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: June 21, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Peter L. Gebrian, Joseph E. Brennan, Ronald G. Barlow, William E. Hudson, William H. Reigle, Jr.