Abstract: A stimulus is configured to treat astigmatism with changes in retinal thickness, independently of, or in combination with, treatment for myopia. In some embodiments, a stimulus pattern is arranged with respect to an astigmatic axis of the eye to decrease ocular growth in relation to the astigmatic axis. In some embodiments, the apparatus is configured to direct light to regions of retina outside the macula in relation to the astigmatic axis of the eye. In some embodiments, the intensity is modulated to provide the effect. A lens, such as a contact lens or spectacle lens may be configured with a plurality of light sources, such as projection units having a light source and focusing optics that work together to project anteriorly or posteriorly defocused images onto the retina at locations eccentric to the fovea.

Abstract: The disclosed invention relates to an improved system and method for treatment of soft tissue, e.g., for treatment of a snoring condition. The system can include a laser source; a hand piece; and a device for directing radiation emitted by the laser source to a treatment area (e.g., an oral treatment area). In some cases, the handpiece can include an optical element (e.g., a lens) mounted within a replaceable cartridge and adapted to modulate a laser beam such that it is non-ablative, prior to its delivery to a treatment region. In various embodiments, the system includes a CO2 laser capable of performing treatment in a more efficient manner than conventional techniques.

Abstract: Provided is a swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.

Abstract: A method for using soft physiotherapy instrument is provided. The method comprises providing a soft physiotherapy instrument comprising a flexible sheet and a controller, applying the flexible sheet of on a user's skin, and turning on the controller and selecting a function button on the controller, inputting a current to a plurality of functional layers in the flexible sheet, and stimulating user's skin with the current.

Abstract: Methods, systems, and apparatus for surgical equipment monitoring are disclosed. In some embodiments, an electronic health records database and a database of surgical tools is provided. At least one sensor and at least one surgical tool are used before, during, or after a surgical procedure. The at least one sensor associated with the at least one surgical tool is monitored for at least one parameter. The monitored data is compared to the expected value of that parameter for the current step in the surgical procedure from the surgical tools database. In response to determining a potential surgical complication, the system generates a notification indicating the potential surgical complication.

Abstract: An assembly for use in a TTField-generating system is disclosed that includes at least one electrode in combination with a polymerized conductive hydrogel and a liquid conductive hydrogel disposed on at least a portion of the polymerized hydrogel. Also disclosed are transducer arrays including the assemblies, as well as kits and methods of producing and using the assemblies, arrays, and systems.

Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging and shock.

Abstract: A method, including receiving from mapping electrodes positioned at locations within a heart, signals indicating electrical activity in tissue contacting the electrodes, and processing the signals to identify, for each location, at least one corresponding LAT in a cycle of a heart. For each location, an earliest LAT in the cycle is identified, and an electroanatomical map including mapping points having respective locations and showing the earliest LAT at each location is generated and rendered. An input selecting a subset of the points is received, and a time range containing the earliest LAT of a majority of the points in the subset is identified. One or more outlying points in the subset are identified, and a second LAT, later than the earliest LAT in the cycle is found among the at least one identified LAT identified at the outlying points. The map is updated to display the found second LAT.

Abstract: An automated laser-surgery system for performing a closed-loop surgical procedure is disclosed. The procedure includes forming a post-procedural goal based on a three-dimensional (3D) image of a surgical site, planning a path for a surgical laser signal based on the post-procedural goal, performing a procedural pass by steering the surgical laser signal along the path, measuring the surface of the surgical site after the procedural pass, updating a model based on the measured effect at the surgical site, and evaluating the success of the procedural pass based on the surface measurement and the post-procedural goal. If necessary, a new path is planned based on the post-procedural goal and the surface measurement a new pass based on that path is performed, and the surface is again measured to evaluate the success of the new pass. These operations are repeated as a closed-loop sequence as many times as necessary to achieve success.

Abstract: Techniques are disclosed for using feature delineation to reduce the impact of machine learning cardiac arrythmia detection on power consumption of medical devices. In one example, a medical device performs feature-based delineation of cardiac electrogram data sensed from a patient to obtain cardiac features indicative of an episode of arrythmia in the patient. The medical device determines whether the cardiac features satisfy threshold criteria for application of a machine learning model for verifying the feature-based delineation of the cardiac electrogram data. In response to determining that the cardiac features satisfy the threshold criteria, the medical device applies the machine learning model to the sensed cardiac electrogram data to verify that the episode of arrhythmia has occurred or determine a classification of the episode of arrythmia.

Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Abstract: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

Abstract: Embodiments of the present disclosure are directed to a wearable phototherapy eye device. In an example, phototherapy can be controlled by varying an emission property of light emitted from the wearable phototherapy eye device to a user eye. In particular, the wearable phototherapy eye device includes a light source oriented to emit the light towards the user eye. The wearable phototherapy eye device also includes controls, such as electrical, mechanical, and/or electro-mechanical controls, to vary the emission property of the light based on an emission target associated with a sleep phase.

Abstract: A patient health management platform determines of a metabolic state for a first time period. The platform generates a patient-specific treatment recommendation for a second time period following the first time period that identifies objectives for the patient to complete to improve the metabolic state determined for the first time period. Periodically during the second time period, the platform receives recordings of patient data indicating foods consumed by the patient, medication taken by the patient, and/or symptoms experienced by the patient. The platform compares the received recordings of patient data from the second time period to the generated patient-specific treatment recommendation to determine a number of objectives completed by the patient and updates a score representing n adherence of the patient to the patient-specific treatment recommendation based the number of completed objectives.

Abstract: A wireless implantable neuromuscular stimulator includes an antenna for producing an induced current in response to being disposed in an electromagnetic field. The antenna includes a substrate having an upper surface and a lower surface. An upper coil including a plurality of coil turns is disposed on the upper surface of the substrate. A lower coil including a plurality of coil turns is disposed on the lower surface of the substrate. The upper and lower coils are electrically connected to each other in parallel. The parallel connection can be facilitated by a plurality of connectors that extend through the substrate and electrically connect the upper coil to the lower coil. In one example configuration, connectors connect each coil turn of the upper coil to a corresponding turn of the lower coil.

Abstract: A system for guiding implantation of an energy delivery component of a cardiac pacing device at a fixation location within a heart of a patient is provided. During a procedure to implant an energy pulse delivery component, the system receives a patient cardiogram collected during pacing of the energy pulse delivery component while the energy pulse delivery component is positioned at a current location within the heart. The system then determines based on the patient cardiogram the current location of the energy pulse delivery component. The system then outputs an indication of the current location to guide affixing of the energy pulse delivery component at the intended fixation location. This process is repeated until the energy pulse delivery component is at the fixation location. The system also evaluates the effectiveness of pacing at intermediate location to optimize the final location based upon simulated electro-mechanics of the system in near-real time.

Abstract: A multi-target vital sign detection system includes a transmitter, a receiver and a processor. The transmitter is configured to transmit a millimeter wave signal to a detection area, and the receiver is configured to receive a reflecting millimeter wave signal reflected by a plurality of targets in the detection area. The processor is configured to: generate signal strength versus distance data by analyzing the received reflecting millimeter wave signal; perform an extreme value reserving process to generate signal extreme value versus distance data; perform a peak search algorithm to obtain a peak list including a plurality of peak values and a plurality of corresponding peak distances; generate a distance array including a plurality of distance variables; and perform a vital sign detection algorithm to generate multiple sets of vital sign data.

Abstract: An ingestible capsule arranged, in use, to cross a human stomach for carrying out a phototherapeutic treatment arranged to combat an infection due to the presence of the bacterium Helicobacter pylori, the ingestible capsule comprising at least one primary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength ?1, at least one auxiliary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength ?2, a wrapper arranged to contain the or each primary light source and the or each auxiliary light source, the wrapper being at least partially transparent to the wavelengths ?1, and ?2, a control unit arranged to selectively activate the or each primary light source and/or the or each auxiliary light source.

Abstract: An implantable fluid pump system is disclosed for supporting or initiating flow inside a hollow organ through which fluid circulates, in particular the heart. The fluid pump system comprises an intracardiac module, which includes two separate fluid channels, each of which possesses an intracardiac fluid channel opening and, located opposite the latter, an extracardiac fluid channel opening, a fastening module, which provides a joining contour for purposes of joining onto the intracardiac module in a fluid-tight manner, and a fastening structure for purposes of intracorporeal fastening onto the hollow organ, and a pump module, which can be mounted in a releasable manner directly or indirectly onto the intracardiac module, and can be attached in a fluid-tight manner to the extracardiac fluid channel openings in order to produce a fluid-tight connection of both fluid channels.

Abstract: An apparatus for pain treatment includes first and second treatment heads, where each treatment head includes one or more light sources with different wavelengths oriented to deliver light to a patient area adjacent to the treatment head. The apparatus includes a first articulated arm pivotably connected to the first treatment head at a first end and a second articulated arm pivotably connected to the second treatment head at a first end. The apparatus includes a handle. A first end of the handle is coupled to the first articulated arm at a second end of the first articulated arm distal to the first end of the first articulated arm. A second end of the handle, distal to the first end of the handle, is coupled to the second articulated arm at a second end of the second articulated arm distal to the first end of the second articulated arm.