Abstract: In some embodiments, a system for providing a therapeutic treatment to a patient's eye includes a treatment beam source configured to transmit a treatment beam along a treatment beam path. The system further includes a processor coupled to the treatment beam source, the processor being configured to direct the treatment beam onto retinal tissue of the patient's eye and deliver a series of short duration pulses from the treatment beam onto the retinal tissue at a first treatment spot to treat the retinal tissue. In some embodiments, a pre-treatment evaluation method using electroretinography (ERG) data may be used to predict effects of treatment beams at different power values and to determine optimal power values.

Abstract: A wireless-connectivity system includes a sensor dongle configured to be electrically connected to a sensor device, a monitor dongle configured to be electrically connected to a medical monitor system, and a dongle-connectivity management hub configured to cause a wireless coupling to be established between the sensor dongle and the monitor dongle. The sensor dongle is configured to receive sensor data from the sensor and wirelessly transmit data to the monitor dongle via the wireless coupling, the data being based at least in part on the sensor data.

Abstract: A method of mitigating the development of myopia, includes measuring elasticity of collagen of an eye; identifying an eye for which the elasticity measured is above a preselected threshold; selectively applying a collagen cross-linking reagent proximate collagen of a sclera of a posterior pole portion of the eye for which the elasticity measured is above the preselected threshold; and irradiating at least the posterior pole portion of the eye with radiation of an appropriate wavelength to initiate covalent bonding and cross-linking of the collagen for which the elasticity measured is above the preselected threshold.

Abstract: Disclosed are devices, systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various located within the associated chamber of the heart. To create a database of dipole densities, mapping information recorded by multiple electrodes located on one or more catheters and anatomical information is used. In addition, skin electrodes may be implemented. Additionally, one or more ultrasound elements are provided, such as on a clamp assembly or integral to a mapping electrode, to produce real time images of device components and surrounding structures.

Abstract: A method for altering an eye color of a patient with a color alteration procedure is disclosed that may include imaging the iris with an image sensor prior to the color alteration procedure to generate an image of the iris. A mapping of the iris may be generated from the image. The mapping may include a number of regions corresponding to varying absorption coefficients of a treatment wavelength in the stromal pigment of the iris. A laser system may be set, based on the mapping, to deliver laser light at a laser power sufficient to cause elimination of at least a portion of stromal pigment in the iris. The laser light may then be delivered with the laser system.

Abstract: The present disclosure relates generally to the use of medical devices for the treatment of vascular conditions. In particular, the present disclosure provides devices and methods for using laser-induced pressure waves created within a sheath to disrupt intimal and medial calcium within the vasculature.

Abstract: A system includes a sensor configured to sense first and second physiological signals produced by a source; and a processing device communicatively coupled to the sensor. The processing device is configured to: receive the first and second physiological signals; determine a first value of a signal characteristic; determine a second value of the signal characteristic; access a scaling map having scaling vectors, and each scaling vector having at least one signal characteristic correction value; determine a scaled first value and a scaled second value based on a first scaling vector and a second scaling vector, respectively; and predict a physiological event based on the scaled first value of the signal characteristic and the scaled second value of the signal characteristic.

Abstract: Optogenetic signal processing is described for an auditory prosthesis with an intracochlear array of optical stimulation sources implanted in a patient having auditory neurons genetically modified with light sensitive ion channels. Stimulation timing signals are generated for the corresponding auditory neurons for each band pass signal based on characteristic temporal fine structure features of the band pass signals. The stimulation timing signals include: i. one or more channel opening signals adapted to open the ion channels of the corresponding auditory neurons, and ii. one or more channel closing signals adapted to close the ion channels of the corresponding ion channels. Optical stimulation signals are then produced for the optical stimulation sources based on the stimulation timing signals.

Abstract: A smart watch described in this document includes hardware and software necessary to obtain motion and sensor data from a user wearing the smart watch. The described smart watch can continuously collect sensor data from the user and combine the sensor data from multiple sensors to enhance the accuracy of the sensor data analysis and provide relevant feedback information to the user. In addition, the described smart watch is capable of pairing with an external personal portable device, such as a smartphone or tablet to correlate the collected sensor data with activities performed by the user on the paired device. The smart device can also transmit data to a cloud server to collect sensor data and correlation analysis data for further analysis and provide statistical analysis of the collected sensor data and correlation analysis data.

Abstract: An implantable medical device (IMD) with a receiver having a higher power mode and a lower power mode. In the higher power mode, the receiver can receive a communication from an external device and pass the received communication to a controller, and in the lower power mode the receiver may not receive the communication from the external device and pass the received communication to the controller. In some cases, the IMD may include a physiological sensor providing an output to the controller, and the controller may control whether the receiver is in the higher power mode or the lower power mode based at least in part on the output of the physiological sensor.

Abstract: Systems and methods configured to provide indications of a subject's fitness based on values of a fitness metric for the subject are disclosed. Exemplary implementations may: obtain fitness information related to the subject; present, based on a change in the first value indicating a decline in the real-time state of health, a first notification of the first value via a watch wearable by the subject; present, based on the change in the first value indicating the decline in the real-time state of health, a second notification related to the subject via a second watch wearable by a second subject and/or a client computing platform associated with an administrator; and present, based on a change in the second value indicating a decline in the future state of health, a third notification via the watch, one or more other watches, and/or the client computing platform.

Abstract: This document discusses, among other things, systems and methods for delivering electrostimulation to specific tissue of a patient. An example of a system can receive a three-dimensional voxelized model representing a plurality of regions each specified as a target region or an avoidance region. The system includes control circuitry to determine a metric value using the voxelized model. The metric value indicates a clinical effect of electrostimulation on the plurality of regions according to a stimulation current and a current fractionalization. The control circuitry can determine a desired stimulation current that results in a first metric value satisfying a clinical effect condition. The system can generate a stimulation configuration including the desired stimulation current and the current fractionalization corresponding to the first metric value, and deliver tissue stimulation according to the stimulation configuration.

Abstract: An intravascular fluid movement device that includes an expandable member having a collapsed, delivery configuration and an expanded, deployed configuration, the expandable member having a proximal end and a distal end, a rotatable member disposed radially and axially within the expandable member, and a conduit coupled to the expandable member, the conduit at least partially defining a blood flow lumen between a distal end of the conduit and a proximal end of the conduit, the conduit disposed solely radially inside of the expandable member in a distal section of the expandable member.

Abstract: The present disclosure relates to an implantable lead comprising an elongated lead body having at least one lumen therein and at least one through hole, and at least one electrically conductive wire. For at least one of said at least one lumen, a first through hole extends from an outer surface of the lead body into said lumen, and an electrically conductive wire is arranged in said lumen at least on one side of said first through hole. Furthermore, said electrically conductive wire is further arranged in a configuration exiting the lumen via said first through hole and wound around a predefined portion of the outer surface of the lead body.

Abstract: Controllers and methods for heart treatments are disclosed herein. The controller can include a communication module that can send and receive data from heart therapy devices. The controller can include memory including stored instruction. The controller can include a processor. The processor can receive a signal of an impending electrical treatment at a processor. The processor can determine a current operating parameter of a blood pump communicatingly coupled with the processor. The processor can determine an adjustment to the operating parameter of the blood pump to affect an impedance of heart tissue to be affected by the impending electrical treatment. The processor can control the blood pump according to the adjustment to the operating parameter of the blood pump.

Abstract: A system to deliver current to an area of interest of a subject is described that includes a power source, a controller electrically coupled to the power source, at least one first electrode electrically coupled to the controller, and at least one second electrode electrically coupled to one of the power source and the controller, with the area of interest positioned between the at least one first electrode and the at least one second electrode. A method of stimulating at least one of bone growth, tissue healing and pain control within an area of interest of a patient is described that includes inserting first and second electrode spaced at a predetermined distance, and further includes directing an electric current between the first and second electrodes so that at least a portion of the electric current passes through the area of interest positioned between the first electrode and the second electrode.

Abstract: A mobile device for measuring at least one electrical biosignal. The device comprises a first input and a second input, a measuring circuit part for providing an output signal indicating the electrical biosignal to be measured, the measuring circuit part comprising a first input and a second input, and a charging circuit part for charging a rechargeable battery inserted in the device, the charging circuit part comprising a first input and a second input. The first input of the measuring circuit part and the first input of the charging circuit part are connected to the first input of the mobile device and the second input of the measuring circuit part and the second input of the charging circuit part are connected to the second input of the mobile device.

Abstract: An optical switch incorporated in a photomedical system, and a method of treating tissue using the optical switch for creating pulsed light. A light source generates an optical beam. An aperture element includes a light-transmitting portion and a light-blocking portion. An optical element such as a mirror, prism or lens directs the optical beam to the aperture element, wherein the optical element is movable for translating the optical beam across the light-transmitting and light-blocking portions of the aperture element, or changing its angle of incidence through the aperture to produce one or more pulses of light from the optical beam. A lens focuses the one or more pulses of the optical beam onto target tissue. A controller controls the movement of the optical element to produce the one or more pulses of light.

Abstract: A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors.

Abstract: A vital-signs monitor patch containing at least two electrodes, a circuit assembly, and a patch body having a chamber in which the circuit assembly is housed. The patch body also contains at least one flexible portion adjacent to the circuit assembly chamber, with at least one electrode attached to the flexible portion. The electrodes are configured for attaching the patch to the skin of a patient.