Abstract: The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.
Type:
Grant
Filed:
August 5, 2016
Date of Patent:
October 1, 2019
Assignee:
Cleveland Medial Devices Inc.
Inventors:
Hani Kayyali, Craig A. Frederick, Christian Martin, Robert N. Schmidt, Brian Kolkowski
Abstract: Various systems and methods are implemented for in vivo use in a living animal. One such method involves stimulating target cells having light-responsive proteins and includes providing an elongated light-delivery structure in a narrow passageway in the animal, the elongated light-delivery structure having separately-activatable light sources located along the length of the elongated light-delivery structure. The method also includes activating less than all the light sources to deliver light to light-responsive proteins adjacent to the activated light sources along the length of the elongated light-delivery structure, thereby stimulating target cells in vivo.
Type:
Grant
Filed:
March 26, 2013
Date of Patent:
October 1, 2019
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: A phototherapy apparatus with interactive user interface for treating biological tissue of an animal or human target. The user interface comprises intuitive graphic menus which allow the clinicians or practitioners to define the properties of the biological tissue through easily observable physical characteristics such as weight, skin color, and hair color of the patient. The central control unit of the phototherapy apparatus then automatically optimizes the parameters of the light source according to the properties of the biological tissue and generates an appropriate treatment protocol to produce the optimum phototherapy result.
Abstract: The systems, environment, and methods, described herein support evaluation of an individual for ASD while in the home environment. Through data collected by a wearable data collection device donned by the individual, eye contact with the caregiver, verbal interaction, and repetitive verbalizations and motions of the head and body may be tracked and objectively quantified during evaluation. Further, the wearable data collection device may support monitoring of brain activity and other physiology which, in turn, may be analyzed by the systems and environment described herein during evaluation to recognize patterns that predict evaluation outcome and other clinical features. Various software modules and tools supported by the wearable data collection device provide training, ongoing progress tracking, and management solutions for individuals living with ASD.
Abstract: An apparatus configured to estimate biometric information includes a sensor configured to measure a light signal reflected from a subject and a temperature of the subject, and a processor configured to perform temperature correction on the light signal reflected from the subject based on the temperature of the subject using a light signal-temperature relationship between the light signal reflected from the subject and the temperature of the subject to thereby obtain a temperature-corrected light signal, and estimate the biometric information of the subject based on the temperature-corrected light signal.
Type:
Grant
Filed:
May 30, 2017
Date of Patent:
August 27, 2019
Assignee:
SAMSUNG ELECTRONICS CO., LTD.
Inventors:
Jung Yong Nam, Joon Hyung Lee, Ki Young Chang, Hyeong Seok Jang
Abstract: A treatment method and apparatus for surgical correction of defective-eyesight in an eye of a patient, wherein a laser device is controlled by a control device, said laser device separating corneal tissue by irradiation of laser radiation to isolate a volume located within a cornea, wherein the control device controls the laser device to focus the laser radiation, by providing target points located within the cornea, into the cornea, wherein the control device, when providing the target points, allows for focus position errors which lead to a deviation between the predetermined position and the actual position of the target points when focusing the laser radiation, by pre-offsets depending on the positions of the respective target points to compensate for said focus position errors.
Type:
Grant
Filed:
October 15, 2018
Date of Patent:
August 27, 2019
Assignee:
Carl Zeiss Meditec AG
Inventors:
Martin Wiechmann, Michael Bergt, Mark Bischoff, Markus Sticker, Gregor Stobrawa
Abstract: The various embodiments disclosed herein relate to modular medical devices, including various devices with detachable modular components and various devices with pivotally attached modular components. Additional embodiments relate to procedures in which various of the devices are used cooperatively. Certain embodiments of the medical devices are robotic in vivo devices.
Type:
Grant
Filed:
February 5, 2018
Date of Patent:
August 13, 2019
Assignee:
Board of Regents of the University of Nebraska
Inventors:
Shane Farritor, Amy Lehman, Mark Rentschler, Nathan Wood, Jason Dumpert, Dmitry Oleynikov
Abstract: A steerable laser probe may include a handle, and inner bore of the handle, an actuation lever of the handle, a housing tube, and an optic fiber disposed within the inner bore of the handle and the housing tube. The housing tube may have a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater than the first stiffness.
Type:
Grant
Filed:
August 31, 2017
Date of Patent:
August 13, 2019
Assignee:
Katalyst Surgical, LLC
Inventors:
Gregg D Scheller, Matthew N Zeid, Craig Moore
Abstract: Provided herein are methods and systems for validating and interpreting respiratory signals in order to provide comprehensive non-invasive methods to monitor patients at risk for respiratory depression and apnea. In the present invention, data from multiple respiratory monitoring technologies (or from multiple channels of one monitoring technology) is fused so that the patient's true respiratory state may be elucidated.
Type:
Grant
Filed:
October 11, 2014
Date of Patent:
August 6, 2019
Assignee:
XHALE ASSURANCE, INC.
Inventors:
Richard J. Melker, Sean Cohen, Huwei Tan
Abstract: Methods for characterizing a circadian rhythm of a wearer of a wearable device are provided. In one example, physiometric measurements are obtained over a period of time by one or more sensors of a wearable device configured to be mounted to a body surface of a wearer. A circadian rhythm of the wearer, such as a sleeping, waking, eating or movement pattern, is characterized based on the physiometric measurements. Based on the identified circadian rhythm, one or more settings of the wearable device, such as a timing or frequency of obtaining physiometric measurements, may be adjusted.
Abstract: Disclosed herein are systems and methods involving the use of magnetic resonance imaging and optogenetic neural stimulation. Aspects of the disclosure include modifying a target neural cell population in a first region of a brain to express light-responsive molecules. Using a light pulse, the light-responsive molecules in the target neural cell population are stimulated. Multiple regions of the brain are scanned via magnetic resonance imaging. The scans allow for observation of a neural reaction in response to the stimulation in at least one of the multiple regions of the brain.
Type:
Grant
Filed:
May 18, 2018
Date of Patent:
August 6, 2019
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: System for monitoring the hydration status of a living being by exploiting the modulation of backscattered RF electromagnetic waves from a wearable patched placed on the skin, said system comprising: a RF-tag adapted to be directly or indirectly fixed to the skin and containing at least one passive integrated circuit coupled to an antenna; an electromagnetic RF power source for supplying different signal frequencies to said RF-tag; a reader adapted to receive and to process the backscattered electromagnetic waves generated by said electromagnetic power source.
Type:
Grant
Filed:
August 31, 2015
Date of Patent:
August 6, 2019
Assignee:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Abstract: A system to deliver current to an area of interest of a subject is described that includes a power source, a controller electrically coupled to the power source, at least one first electrode electrically coupled to the controller, and at least one second electrode electrically coupled to one of the power source and the controller, with the area of interest positioned between the at least one first electrode and the at least one second electrode. A method of stimulating at least one of bone growth, tissue healing and pain control within an area of interest of a patient is described that includes inserting first and second electrode spaced at a predetermined distance, and further includes directing an electric current between the first and second electrodes so that at least a portion of the electric current passes through the area of interest positioned between the first electrode and the second electrode.
Type:
Grant
Filed:
November 8, 2017
Date of Patent:
July 30, 2019
Assignee:
Washington University
Inventors:
Eric Claude Leuthardt, Daniel W. Moran, Matthew R. MacEwan
Abstract: In some embodiments, the disclosed subject matter involves identifying environmental factors and user context that affect sleep quality. Embodiments use information about the static sleep environment, as well as dynamic environmental factors, such as sound, light, movement, correlated with user context, such as physical and emotional state, as well, as recent behavior to classify sleep data. The correlated and classified sleep data may be used to provide change recommendations, where implementing the recommended change is believed to improve the user's sleep quality. Other embodiments are described and claimed.
Type:
Grant
Filed:
March 30, 2017
Date of Patent:
July 23, 2019
Assignee:
Intel Corporation
Inventors:
Lama Nachman, Rita H. Wouhaybi, Sangita Ravi Sharma, Jonathan J. Huang, Jennifer Anne Healey, Lenitra M. Durham, Chieh-Yih Wan, Omar Ulises Florez Choque
Abstract: A hand-held, hand-operated apparatus for rotating, or spinning, rotatably oscillating and/or inducing back and forth longitudinal movement in a device, such as an elongated medical device. A drive shaft of the hand-held, hand-operated rotational drive apparatus includes a ratcheting mechanism capable of enabling oscillating (repeated forward and reverse) rotation of a device that has been coupled thereto when there is little or no resistance on the rotated device, and of enabling an actuator to return to a position that will enable further forward, or driving, rotation of the drive shaft and the rotated device when resistance on the rotated device prevents the rotated device and the drive shaft from rotating in a reverse direction.
Abstract: There has been no sufficient study to address an issue caused in the use of an open-air type audio device. Therefore, provided is an audio device with an actually useful organism sensor. In particular, the audio device includes an audio unit 10 to externally abut on the ear without being inserted thereinto, and an organism sensor unit 70 to be inserted into the ear.
Abstract: Methods to provide glycemic control and therapy management based on monitored glucose data, and current and/or target HbA1C levels are provided. Systems to provide glycemic control and therapy management based on monitored glucose data, and current and/or target HbA1C levels are provided. Kits to provide glycemic control and therapy management based on monitored glucose data, and current and/or target HbA1C levels are provided.
Type:
Grant
Filed:
October 20, 2017
Date of Patent:
June 25, 2019
Assignee:
Abbott Diabetes Care Inc.
Inventors:
Marc Barry Taub, Timothy Christian Dunn, Nathan Christopher Crouther
Abstract: Disclosed are devices, systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various located within the associated chamber of the heart. To create a database of dipole densities, mapping information recorded by multiple electrodes located on one or more catheters and anatomical information is used. In addition, skin electrodes may be implemented. Additionally, one or more ultrasound elements are provided, such as on a clamp assembly or integral to a mapping electrode, to produce real time images of device components and surrounding structures.
Type:
Grant
Filed:
March 20, 2018
Date of Patent:
June 11, 2019
Assignee:
ACUTUS MEDICAL INC.
Inventors:
Christoph Scharf, Gunter Scharf, Randell L. Werneth
Abstract: A tool introducer is configured for introduction in an elongated body including a straight tube, wherein the tube encloses a tube lumen opened at its distal end with a tube opening. The tool introducer includes locking means to selectively lock or unlock an interchangeable surgical tool to the tube from displacing axially and/or rotationally in the tube lumen, the locking means being configured such that, at the locking, a tool connector of the tool projects towards the tube opening and is distanced therefrom by at least 3 cm. A method includes positioning the surgical tool introducer such that a distal portion thereof projects in a body cavity, manipulating and/or extending the tool introducer to reach and engage an elongated shaft introduced percutaneously into the body cavity; and inserting the elongated shaft into the tube lumen via the tube opening and connecting the tool to the elongated shaft.
Abstract: Systems and/or methods for assessing the sleep quality of a patient in a sleep session are provided. Data is collected from the patient and/or physician including, for example, sleep session data in the form of one or more physiological parameters of the patient indicative of the patient's sleep quality during the sleep session, a subjective evaluation of sleep quality, etc.; patient profile data; etc. A sleep quality index algorithm, which optionally may be an adaptive algorithm, is applied, taking into account some or all of the collected data. Sleep quality data may be presented to at least the patient, and it may be displayed in any suitable format (e.g., a format useful for the patient to be appraised on the progress of the treatment, a format useful for a sleep clinician to monitor progress and/or assess the effectiveness of differing treatment regimens, etc).
Type:
Grant
Filed:
November 20, 2013
Date of Patent:
May 28, 2019
Assignee:
ResMed Limited
Inventors:
Renee Frances Flower, Philip Rodney Kwok, Muditha Pradeep Dantanarayana, Ron Richard