Patents Examined by Jon P. Weber
  • Patent number: 8900832
    Abstract: The present invention relates to a method for the production of fat with a principal application as transportation biofuel or a component or raw material therefor. According to the method, cell masses, cell suspensions and/or liquid phases formed in the production of single cell oil, and/or biomass-containing side streams or microorganism cell masses for another purpose and/or originating from other sources, are contacted with a fat-production capable microorganism and the organism is allowed to produce fat. The resulting fat is recovered or the microorganism mass is passed to a single-cell oil production process. By means of the invention, the organic matter present in the cell mass and side streams of single-cell oil can be re-utilized for the production of the single-cell oil, thereby improving a total fat yield, as well as reducing an organic load of the side streams.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: December 2, 2014
    Assignee: Neste Oil Oyj
    Inventors: Heidi Kahelin, Simo Laakso, Ossi Pastinen, Miia Mujunen, Tarja Suomalainen
  • Patent number: 8894975
    Abstract: Methods are provided for, inter alia, determining the presence of leukemia cells in a subject, determining the change or potential change in the number of leukemia cells in the subject with time, determining whether a tissue in a subject contains a plurality of leukemia cells or a plurality progenitor leukemia cells, and determining whether a leukemia therapy administered to a subject is capable of decreasing the number of leukemia cells in a tissue of the subject.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: November 25, 2014
    Assignee: The Regents of the University of Colorado, a body Corporate
    Inventors: Lia Gore, Deborah Deryckere, Margaret E. Macy, Natalie Serkova
  • Patent number: 8895282
    Abstract: A method for treatment and/or prevention of common cold caused by rhinovirus, wherein a patient in need is treated with a medicament including a hydrogen peroxide producing enzyme.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: November 25, 2014
    Assignee: Tanomed AB
    Inventor: Krister Tano
  • Patent number: 8895262
    Abstract: The staining method for identification of flatworms includes placing a sample flatworm specimen on a microscope slide, mounting the flatworm specimen on the slide with a small amount of lactophenol cotton blue (LPCB) stain, waiting two to three minutes for the stain to be absorbed by flatworm tissues, covering the specimen with a cover slip, and examining the stained specimen with a microscope to identify the species-distinctive organs of the flatworm. For permanent mounting, the cover slip may be sealed to the microscope slide by nail polish. The method is effective for trematodes (flukes) and cestodes (tapeworms). Before examination, the specimen may be preserved by obtaining the flatworm from a carrier or host, washing the flatworm in saline and preserving the flatworm in alcohol, e.g. 70% alcohol.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: November 25, 2014
    Inventor: Adawia A. M. Henedi
  • Patent number: 8895265
    Abstract: Methods are disclosed for increasing the level of C5 monosaccharides produced from lignocellulosic biomass using a multistage fractionation process to handle recalcitrant C5 oligosaccharides without producing unwanted degradation products. Methods for reducing C5 monosaccharides degradation products produced from lignocellulosic biomass are also disclosed. In addition, compositions and products produced by the methods are disclosed.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: November 25, 2014
    Assignee: Renmatix, Inc.
    Inventor: Phillip R. Gibbs
  • Patent number: 8889351
    Abstract: The disclosure provides articles and methods useful for detecting a discrete source of DNase activity. DNase-producing microorganisms can be detected. The device can further include selective agents and/or indicators to differentiate groups or species microorganisms. Methods of use include detecting or enumerating DNase-producing microorganisms.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: November 18, 2014
    Assignee: Innovative Properties Company
    Inventors: Patrick A. Mach, Michelle L. Rosauer, Michael E. Hughes
  • Patent number: 8889372
    Abstract: The presently disclosed subject matter provides real-time adaptive manipulations of conditions in a bioreactor to optimize biochemical reactions occurring within the bioreactor. Optimization of a bioreactor does not need to be performed in small-scale, but real-time adaptive manipulations can occur in a bioreactor while the bioreactor is being used.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: November 18, 2014
    Inventor: Michael Cushman
  • Patent number: 8883472
    Abstract: A method for extracting water from an aqueous solution of a protein comprising the steps of: (a) intermixing the aqueous solution of the protein with a sufficient quantity of at least one glycol ether at a temperature at least 30 centigrade degrees above the lower critical solution temperature (LCST), preferably at least 20 centigrade degrees above the LCST, and most preferably at least 10 degrees above the LCST, to form a suspension comprising a concentrated aqueous protein phase and a liquid organic phase comprising said at least one glycol ether and at least 10 percent water extracted from the aqueous solution of the protein, wherein the glycol ether has an inverse solubility in water, with the proviso that the solubility of the glycol ether in water is significantly less than the solubility of water in the glycol ether, and the glycol ether does not significantly deactivate the protein, and (b) separating the concentrated aqueous protein phase formed in step (a) from at least a portion of the liquid orga
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: November 11, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventors: Felipe A. Donate, Timothy C. Frank, Barbara J. Grabowski
  • Patent number: 8883471
    Abstract: A material comprising positively and negatively charged nanoparticles, wherein one of said nanoparticles contained a magnetically responsive element, are combined with a support molecule, which is a long natural or synthetic molecule or polymer to make a magnetic nanoparticle assembly. When the magnetic nanoparticle assembly is combined with cells, it will magnetize those cells. The magnetized cells can then be washed to remove the magnetic nanoparticle assembly and the magnetized cells manipulated in a magnetic field.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: November 11, 2014
    Assignee: N3D Biosciences, Inc.
    Inventor: Glauco R. Souza
  • Patent number: 8883137
    Abstract: A nutritional composition comprising by weight: between 0.05 and 30% selenium-enriched yeast; between 1 and 90% yeast beta-glucan; between 0.5 and 60% Vitamin C; and between 0.5 and 40% Vitamin E. The composition features anti-oxidative, anti-aging, cancer-preventing, and immune-stimulating properties.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: November 11, 2014
    Assignee: Angel Yeast Co., Ltd.
    Inventors: Xuefeng Yu, Zhihong Li, Minghua Yu, Juan Yao, Yan Zhang, Yamin Zhu
  • Patent number: 8883469
    Abstract: The description relates to a method of producing bioethanol by separating lignin from a crushed lignocellulose biomass and obtaining cellulose and, if required, hemicellulose and additionally processing the cellulose or the mixture of cellulose and hemicellulose to form sugars and subsequently form bioethanol. The method is characterized in that crushed lignocelluloses biomass is treated with an alkanolamine for extracting the lignin therein, the lignin solution is separated, the residue containing cellulose/hemicellulose is converted to sugars without drying, and the sugars are fermented to obtain bioethanol. The raw cellulose (cellulose/hemicellulose), owing to its high reactivity, can easily be converted into sugar, which can be fermented to form bioethanol.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: November 11, 2014
    Assignee: Zylum Beteiligungsgesellschaft mbH & Co., Patente II KG
    Inventor: Ties Karstens
  • Patent number: 8883451
    Abstract: Methods are disclosed for increasing the level of soluble C5 saccharides produced from lignocellulosic biomass comprising acidifying fractionated lignocellulosic biomass to prevent the recondensation of soluble C5 saccharides, including C5 oligosaccharides and xylose and arabinose monomers, to insoluble higher molecular weight C5 oligosaccharides.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: November 11, 2014
    Assignee: Renmatix, Inc.
    Inventor: Phillip R. Gibbs
  • Patent number: 8877467
    Abstract: Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy materials, to produce a product or intermediate, e.g., energy, a food, a fuel, or a material.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: November 4, 2014
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman
  • Patent number: 8877472
    Abstract: Corn or soy plant biomass is electron beam irradiation processed and saccharified to produce sugars. The sugars are then converted to products such as alcohols, organic acids, hydrocarbons, hydrogen, proteins, carbohydrates, fats, oils, lipids, amino acids, vitamins, and mixtures thereof.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: November 4, 2014
    Assignee: Xyleco, Inc.
    Inventor: Marshall Medoff
  • Patent number: 8877473
    Abstract: The present application provides stabilized formulations of furin (e.g., rfurin) containing a sugar, sugar alcohol, and/or non-ionic surfactant. As compared to non-stabilized compositions, the furin formulations disclosed herein retain greater amounts of furin activity and monomeric furin content, while reducing furin aggregation when stored and/or subjected to mechanical stress. Also provided are methods for stably diluting furin (e.g., rfurin) compositions.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: November 4, 2014
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Meinhard Hasslacher, Andrzej Citkowicz, Catherine White, Ken Franke
  • Patent number: 8871482
    Abstract: Functionalized substrate materials, for example inorganic particles and/or synthetic polymeric particles, are used to enhance bioprocesses such as saccharification and fermentation.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: October 28, 2014
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Harrison Medoff
  • Patent number: 8865397
    Abstract: For cooling organs and tissues in transplantation medicine, only ice preparations are used so far which are not soft like a gel and are brought to the necessary degree of comminution by mechanically comminuting frozen, sterile, pyrogen-free isotonic infusion solutions, such as 5% glucose or 0.9% saline, with great effort. The lack of gel-like consistency of the preparations and the expensive production process are very disadvantageous. Therefore, it was necessary to produce a cooling preparation for transplantation medicine, which in a temperature range from ?5° C. to 4° C. is gel-like and soft, transparent and sufficiently mechanically stable and yet remains formable. In accordance with the invention, such preparation can be produced from gelatin solutions in the concentration range of 3-20 wt-%, which are isotonized or adjusted to 280-650 mosmol/kg and are almost pH-neutral, by simple cooling and/or freezing.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: October 21, 2014
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Bernd W. Mueller, Klaus Sommermeyer
  • Patent number: 8859220
    Abstract: A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: October 14, 2014
    Assignee: Promega Corporation
    Inventors: Erika Hawkins, James J. Cali, Samuel Kin Sang Ho, Martha A. O'Brien, Richard Somberg, Robert F. Bulleit, Keith V. Wood
  • Patent number: 8859225
    Abstract: Systems and methods are provided for optically measuring ion concentrations in biological samples. The systems and methods employ polymer-based optical ion sensors that include ion-selective ionophores and a pH sensitive chromionophore. Electrodes are providing for electrically stimulating the biological samples.
    Type: Grant
    Filed: October 15, 2009
    Date of Patent: October 14, 2014
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventors: Daniel I. Harjes, Heather A. Clark
  • Patent number: 8852907
    Abstract: The efficient production of ethanol from low-cost biomass (e.g., corn, sugar beets, sugar cane, switchgrass and/or paper) has become increasingly important in making ethanol competitive with gasoline and decreasing the United States' dependence on foreign oil. For example, to reduce the cost of transporting biomass to ethanol production facilities, mobile systems for producing ethanol from biomass are provided. Also provided are small-scale ethanol production facilities. For example, instead of transporting biomass to the production facility, the facility is transported to the biomass or is located nearby the source of the biomass. The ethanol production facilities or components thereof may be transported via land, water, or air. Production of other products, such as hydrocarbons, natural gas, hydrogen gas, plastics, polymers, and proteins, can also be made by the methods and facilities. Any product described herein can be made in finished form or un-finished form and moved, e.g., to a fixed facility, e.g.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: October 7, 2014
    Assignee: Xyleco, Inc.
    Inventor: Marshall Medoff