Patents Examined by Jose? G. Dees
  • Patent number: 6565890
    Abstract: A compound for use especially as an antiviral drug, mainly containing salts of heteropolyanions consisting of a tungstoantimonate (III) vanadium-mixed metal oxide or related salts represented by formula [(XW9O33)2V3O3]P−, where p is a positive number between 9 and 12 and X is Sb, P. As or Bi and especially Sb. An antiviral drug having a broad spectrum of antiviral activity, high potent efficacy and low toxicity is provided.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: May 20, 2003
    Assignee: Polytronics, Ltd.
    Inventors: Shiro Shigeta, Toshihiro Yamase
  • Patent number: 6562358
    Abstract: A protectant composition comprising vernix for a skin curative and skin protectant effect and a method of using the composition. A natural or synthetic vernix is dispersed in an effect amount and is applied to a surface. The method may be used to repel a naturally occurring agent such as water, or a synthetic agent to which exposure may occur, for example, in an occupational setting.
    Type: Grant
    Filed: May 8, 2001
    Date of Patent: May 13, 2003
    Assignee: Children's Hospital Medical Center
    Inventors: Steven B. Hoath, Martha O. Visscher
  • Patent number: 6562325
    Abstract: The present invention is directed to a low VOC, non-aerosol, polyacrylic acid containing hair cosmetic compositions which contain stabilized starches, particularly those derivatized by alkylene oxides, about 01.-0.0% polyacrylic acid, up to about 15% solvent, and water. The derivatized starch may be hydrolyzed, particularly enzymatically hydrolyzed by at least one endo-enzyme. In addition, the starch may be cationically modified with a low degree of substitution. Use of such starches is novel and advantageous in that they are compatible with polyacrylic acid, providing a clear, solution with a stable viscosity. Further, the resultant composition provides a clear film which is not tacky, good stiffness, and improved humidity resistance.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: May 13, 2003
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: Melissa J. Vitale, Maria Tolchinsky, Gary T. Martino, Daniel B. Solarek, Ian W. Cottrell
  • Patent number: 6562331
    Abstract: A mating disruption method for the control of insect pests comprises releasing a sex pheromone in a field wherein an adsorption of the sex pheromone to a soil in the field is decreased.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: May 13, 2003
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Tatsuya Ito, Takehiko Fukumoto, Kinya Ogawa, Fumiaki Mochizuki
  • Patent number: 6562353
    Abstract: Cinnamic acid and derivatives thereof are well suited for promoting desquamation and/or stimulating epidermal renewal and/or combating intrinsic/extrinsic aging of the skin of a human subject in need of such treatment, by topically applying thereto, for such period of time as required to elicit the desired response, a cosmetically/therapeutically effective amount of cinnamic acid and/or of at least one derivative thereof.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: May 13, 2003
    Assignee: Societe L'Oreal S.A.
    Inventors: Lionel Breton, Christel Liviero
  • Patent number: 6558683
    Abstract: Emulsifier-free cosmetic or dermatological preparations, which are finely dispersed systems of the oil-in-water type, comprising 1. an oil phase, 2. an aqueous phase and 3. one or more types of micronized, inorganic pigments which a) have an average particle size of less than 200 nm, and whose particles b) have both hydrophilic and lipophilic properties, i.e. have an amphiphilic character, and thus position themselves at the water/oil interface, and which c) are selected from the group consisting of metal oxides, which d) are optionally coated on the surface and also optionally comprising further cosmetic or pharmaceutical auxiliaries, additives and/or active ingredients.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: May 6, 2003
    Assignee: Beiersdorf AG
    Inventors: Heinrich Gers-Barlag, Anja Müller
  • Patent number: 6558710
    Abstract: Compositions including zinc compounds and select amino acids in a carrier base, and methods of skin treatment with such compositions, are described. The compositions are useful for healing skin and minimizing the irritation incurred from contact with the zinc compound without loss of zinc availability during absorption into the integument.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: May 6, 2003
    Inventor: Helen Rebecca Godfrey
  • Patent number: 6558667
    Abstract: A method for treating a patient suffering from a renal failure progressed to a stage at which an initiation of a dialysis therapy is required, comprising combining a peritoneal dialysis and an administration of a spherical carbon, is disclosed.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: May 6, 2003
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventor: Tsutomu Nakanishi
  • Patent number: 6558681
    Abstract: A cosmetic product and the like, including a deodorant, comprising a dicarboxylic acid and sodium bicarbonate preferably dihydroxybutanedioic acid and sodium bicarbonate and most preferably comprising cream of tarter and sodium bicarbonate. A mixture of sodium bicarbonate, cream of tarter and water forms a paste which hardens into a solid over a period of a few hours. The mixture provides a solid material which is highly stable. It does not dissolve quickly and does not effervesce, but instead remains essentially stable and retains it's solid form.
    Type: Grant
    Filed: December 7, 2001
    Date of Patent: May 6, 2003
    Assignee: Lush Limited
    Inventors: Helen Ambrosen, Mark Constantine, Margaret Constantine
  • Patent number: 6558696
    Abstract: The invention relates to a transdermal therapeutic system (TTS) containing desoxypeganine (1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline) as the active component, wherein the TSS includes a back layer impermeable to desoxypeganine and an adhesive reservoir layer that contains 10-80 weight percent polymeric material, 0.1-30 weight percent desoxypeganine and/or the pharmaceutically acceptable salts thereof and optionally a softening agent in proportions of 0.1-30 weight percent.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: May 6, 2003
    Assignees: LTS Lohmann Therapie Systeme AG, HF Arzneimittelforschung
    Inventors: Thomas Hille, Lothar Deurer
  • Patent number: 6559290
    Abstract: An adsorbent for removing a chemokine except interleukin-8 in body fluid, which comprises a solid material having an anionic functional group, a method for efficiently removing a chemokine except interleukin-8 in body fluid, which comprises by bringing the above adsorbent into contact with body fluid containing the chemokine and an adsorber for removing a chemokine except for interleukin-8 using the above adsorbent.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: May 6, 2003
    Assignee: Kaneka Corporation
    Inventors: Masaru Nakatani, Shigeo Furuyoshi, Satoshi Takata
  • Patent number: 6555097
    Abstract: Cosmetic product systems comprise a transfer resistant, flexible film forming cosmetic product having a solubility parameter on the Hildebrand scale of less than or equal to 8.5 (calories/cm3)½, and a second composition comprising an oil having a C log P value greater than or equal to 13. The oil is selected from the group consisting of polyol fatty acid polyesters, triglycerides, glycerin/diethylene glycol/adipate cross polymers and mixtures thereof.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: April 29, 2003
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Elliot Rabe, Lee Ellen Drechsler, Edward Dewey Smith, III, Terutomo Dohmae, Christina M. Hines
  • Patent number: 6555103
    Abstract: The present invention is concerned with a biomedical molding comprising a non-biodegradable biocompatible organic polymer comprising attached to its surface radicals of formula wherein the variables are as defined in the claims. The biomedical moldings of the invention are radiation sensitive and may be used, for example, as intraocular lens in ophthalmic surgery.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: April 29, 2003
    Assignee: Novartis AG
    Inventors: Jörg Leukel, Peter Chabrecek, Dieter Lohmann
  • Patent number: 6552050
    Abstract: The present invention is directed to methods of using pro-NAD agents capable of enhancing the dermal and epidermal skin cell NAD content. These pro-NAD agents may be administered topically, orally, or parenterally to enhance DNA repair and other protective responses to DNA damage. The invention further relates to pharmaceutical compositions comprising pro-NAD agents that effectively elevate intracellular NAD content. Finally, the invention relates to the method of using the pro-NAD agents to treat disorders such as sunburn and other skin deterioration that results from DNA damage in skin cells.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: April 22, 2003
    Assignee: University of Kentucky Research Foundation
    Inventors: Elaine L. Jacobson, Myron K. Jacobson
  • Patent number: 6552024
    Abstract: Mucosal surface-coat-forming film dosage units containing a water-soluble hydrocolloid, an effective dose of an active agent and a mucosal adhesion enhancer; wherein the active agent is encapsulated within a polymer which is chemically or physically distinct from the hydocolloid; wherein the mucosal adhesion enhancer is a starch graft copolymer; wherein the film exhibits a dry tack value of less than 3.5 g, a wet tack of greater than 35 g, a gelation temperature that is greater than 70° C. for a 2% polymer solution, a dry film thickness of less than 20 mil, a water content of 0.5 to 10%, a tensile strength greater than 1500 psi, a modulus in the range of 35,000 to 300,000 psi, a % elongation of less than 20%, a tear probagation resistance of 0.001 to 1 N, and a dissolution time in the range of 1 to 600 seconds upon application to an oral mucosal surface.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: April 22, 2003
    Assignee: Lavipharm Laboratories Inc.
    Inventors: Li-Lan H. Chen, William R. Pfister, Donald W. Renn, Thitiwan Buranachokpaisan, James Osborne, Hock Seng Tan, Li Tao
  • Patent number: 6548051
    Abstract: Hair styling compositions that comprise at least one adhesive particle, optionally in a cosmetically acceptable carrier, wherein said at least one adhesive particle comprises at least one substrate and an at least partial coating, wherein said at least partial coating comprises at least one adhesive, wherein the at least one substrate and the at least partial coating are not the same, and wherein the at least one adhesive particle has a mean length greater than 1 micron. The present invention also relates to methods of providing a holding and/or reshapable effect to the hair using the compositions of the invention and methods of manufacturing of said compositions.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: April 15, 2003
    Assignee: L′Oreal
    Inventors: Nathalie Garnier, Henri Samain
  • Patent number: 6548078
    Abstract: The present invention relates to a method for administering a corticosteroid to a posterior segment of an eye. In the method, a sustained release device is implanted to deliver the corticosteroid to the eye. The aqueous corticosteroid concentration remains less than vitreous corticosteroid concentration during release of the corticosteroid from the device.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: April 15, 2003
    Assignee: Control Delivery Systems
    Inventors: Hong Guo, Paul Ashton
  • Patent number: 6544542
    Abstract: The object of the present invention is to provide a pharmaceutical composition optimized for the administration of a drug, particularly a drug which is only sparingly soluble in water, by way of inhalation. The present invention is a fat emulsion for inhalational administration, or a lyophilized composition thereof, which is an o/w fat emulsion comprising fat emulsion particles essentially composed of an oil component, an emulsifying agent and a drug as dispersed in water, characterized in that the average particle diameter of said fat emulsion particles lies within the range of 5˜100 nm. With the aid of a suitable inhaler, the inhalant of the invention readily yields a mist of aerosol particles fine enough to reach the alveolus; the inhalant is well amenable to size control of the aerosol particles.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: April 8, 2003
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Satoru Sonoke, Junzo Seki
  • Patent number: 6544554
    Abstract: Controlled-release formulation having such a portion that the core and a drug release layer each of which has been formulated to effect rapid or gradual release of at least one drug the release of which is to be controlled is covered either partly or entirely with a release control layer that is produced by adding pharmaceutically acceptable additives to at least one base selected from among fumaric acid, DL-tryptophan and L-tyrosine and which is substantially free from the drugs the release of which is to be controlled.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: April 8, 2003
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroyuki Maeda, Yutaka Ogawa, Yoshimitsu Iida
  • Patent number: 6541018
    Abstract: The present invention provides a nanoemulsion, that includes: an oily phase dispersed in an aqueous phase; and at least one glycerol fatty ester surfactant which is solid at a temperature of less than or equal to 45° C.; wherein the oily phase includes oil globules having a number-average size of less than 100 nm; wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion and methods for its use. Ideally, the emulsion is transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties. The nanoemulsion is particularly useful in the cosmetics and dermatological fields, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and, in the ophthalmological field, as an eye lotion for treating the eyes.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: April 1, 2003
    Assignee: L'Oreal
    Inventors: Jean-Thierry Simonnet, Odile Sonneville, Sylvie Legret