Abstract: Use as preservative in formulations for topical use containing water of a component A): a (per)fluoropolyether phosphate of general formula:
Rf—[CF2CH2—Q—L—P(O) (OZ1) (OZ2)]l (I)
wherein l=1 or 2; L is a bivalent linking group; Z1 equal to or different from Z2 selected from H, alkaline or ammonium cation, di- or tri-alkanolammonium cation, di- or tri- or tetra-alkylammonium cation; Rf is a (per)fluoropolyether chain having number average molecular weight in the range from about 400 to about 1,800.
Abstract: A human scent control device including a collapsible conical housing having a bottom end of larger circumference than the top end and having a structural support means consisting of several rigid rings attached within said housing. An exhaust fan motor is affixed within the top of the housing for drawing human scent through one or more filters retained by the rings. The device is provided velcro straps to attach the device to a tree or stand to suspending the conical housing above the area occupied by a human.
Abstract: An artificial bone promotive of osteoanagenesis comprising a calcium phosphate cement and a linear polyphosphate, wherein the calcium phosphate cement comprises &bgr;-tricalcium phosphate, monocalcium phosphate, calcium sulfate hemihydrate and other additives. The artificial bone is non-toxic to the body chemically stable, and has an excellent biodegradability. The artificial bone may be applied as substitutes for bone cements, allografts and autografts.
Type:
Grant
Filed:
July 25, 2000
Date of Patent:
March 25, 2003
Assignee:
Kyung Won Medical Co., Ltd.
Inventors:
Soo Kyung Chae, Hong Yeoul Kim, Ho Yeon Lee, Chang Hun Lee, Kang Moon Seo
Abstract: The invention is directed to a filamentous porous film that can act as a support for cellular attachment, growth and organization. The film is formed from filaments which define a matrix structure with pores.
Type:
Grant
Filed:
June 5, 2001
Date of Patent:
March 25, 2003
Assignee:
Atrix Laboratories, Inc.
Inventors:
Deryl D. Swanbom, Richard L. Dunn, Michelle Botz, Kenneth C. Godowski, Scott Jeffers
Abstract: A method of preparation of a treated Spirulina compound includes the steps of rehydrating desiccated Spirulina, stressing the culture and freeze drying to a powder. The resultant compound has activity as an anti-viral compound and an anti-bacterial compound. It is capable of effecting repair of skin defects in mammals and acting as a preventative agent to skin defects.
Type:
Grant
Filed:
June 8, 1999
Date of Patent:
March 25, 2003
Inventors:
Kelvin Winston Duncan, Angus Ian Macrae
Abstract: A process for the treatment of grasslands against insects, comprising applying an effective quantity of 1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-3-cyano-4-[(trifluoromethyl)-sulphinyl]-5-aminopyrazole to the grasslands.
Abstract: A method for the preparation of compositions, preferably pharmaceutical compositions, in form of expanded, mechanically stable, lamellar, porous, sponge-like or foam structures out of solutions and dispersions results in a favored pharmaceutical product. This method comprises the steps of a) preparing a solution or a homogeneous dispersion of a liquid and a compound selected from the group consisting of one or more pharmaceutically active compounds, one or more pharmaceutically suitable excipients, and mixtures thereof, followed by b) the expansion of the solution or the homogeneous dispersion without boiling.
Abstract: The present application relates to a composition in the form of an oil-in-water emulsion comprising an oily phase dispersed in an aqueous phase, characterized in that the composition is free of surfactant and in that it contains cellulose fibrils which have a length of greater than 1 micron and a length/diameter ratio of greater than 30. The invention also relates to the use of the composition, especially for the care, the treatment, the makeup or the cleansing of the skin, lips, eyelashes and/or hair, as well as for the care of sensitive or dry skin.
Abstract: Pharmaceutical composition comprising at least one active ingredient and hydroxypropylmethylcellulose, highly substituted hydroxypropylcellulose, and/or ethylcellulose as disintegrants, in quantities less than 15% by weight of the composition and in a form providing a disintegrant effect while avoiding the formation of a continuous matrix.
Abstract: The present invention relates to microcapsules with an aqueous core containing at least one water-soluble cosmetic or dermatological active principle, and with a polymeric and/or waxy envelope, in which the said envelope consists
of at least one polymer chosen from polycaprolactone, poly(3-hydroxybutyrate), poly(ethylene adipate), poly(butylene adipate), cellulose esters of at least one C1-C4 carboxylic acid, copolymers of styrene and of maleic anhydride, copolymers of styrene and of acrylic acid, styrene-ethylene/butylene-styrene block terpolymers, styrene-ethylene/propylene-styrene block terpolymers and terpolymers of ethylene, of vinyl acetate and of maleic anhydride, and/or
of at least one wax chosen from beeswax, polyglycerolated beeswax, hydrogenated plant oils, paraffin with a melting point above 45° C., and silicone waxes.
Abstract: The present invention provides a non-invasive method for administering polypeptides across epithelial membranes. The formulations in the present invention comprise solid polypeptide particles mixed with a permeation enhancer and excipients which are dispersed in a media for oral or intranasal administration. Also provided in the present invention is a process to prepare the formulations.
Type:
Grant
Filed:
May 14, 2001
Date of Patent:
March 11, 2003
Assignee:
DelRx Pharmaceutical Corporation
Inventors:
Randall E. McCoy, Robert O. Williams, III, Miles A. Libbey, III
Abstract: The invention relates to aqueous dispersions of sparingly water-soluble or water-insoluble organic UV filter substances, which comprise at least one sparingly water-soluble or water-insoluble organic UV filter substance as colloidally disperse phase in amorphous or partially amorphous form.
Type:
Grant
Filed:
January 30, 2001
Date of Patent:
March 11, 2003
Assignee:
BASF Aktiengesellschaft
Inventors:
Robert Heger, Helmut Auweter, Wilma M. Dausch, Georg Konrad Zwissler, Thomas Wünsch
Abstract: In accordance with the present invention, there are provided stabilized total nutrient admixture (TNA) compositions which are useful for the in vivo parenteral delivery of pharmacologically acceptable lipids or fats, as well as methods for the preparation thereof. In particular, the pharmacologically acceptable lipid or fat is contained within a protein walled shell. In a particular embodiment of the invention, a TNA composition using human serum albumin (HSA) as a stabilizer has been prepared as a convenient three-in-one formulation (i.e., containing a fat emulsion, dextrose, and amino acids plus electrolytes). This “three-in-one” formulation can be prepared in liquid form or in dry form (comprising submicron-sized nanoparticles). The dried material is stable, even under long term storage, and is easily reconstituted immediately before use by simply adding sterile water (with or without vitamin supplementation) This serves to rehydrate the powder into a TNA suitable for injection.
Type:
Grant
Filed:
December 7, 1999
Date of Patent:
March 4, 2003
Assignee:
American Bioscience, Inc.
Inventors:
Shlomo Magdassi, Andrew Yang, Chunlin Tao, Neil P. Desai, Zhiwen Yao, Patrick Soon-Shiong
Abstract: A composition comprising, in a physiologically acceptable medium, at least one sapogenin and a solubilizing system comprising: (a) at least one non-emulsifying ester of a fatty acid and/or of a fatty alcohol whose hydrocarbon-based chain contains at least 8 carbon atoms, or a plant oil, and (b) at least one branched fatty alcohol whose hydrocarbon-based chain contains at least 8 carbon atoms and/or at least one lipophilic UV screening agent. The solubilizing system according to the invention makes it possible to dissolve a sufficient amount of sapogenin, without recrystallization, for a period of time which is acceptable for cosmetic or dermatological use.
Abstract: A solid composition for topical application comprising, in an aqueous phase, a gelling system comprising (i) gellan gum, (ii) at least one other hydrocolloid chosen from the group formed by xanthan gum, carboxymethylcellulose, hydroxypropylcellulose, methylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose, agar-agar, carrageenans, alginates, carob gum, guar gum, gum arabic, karaya gum, gum tragacanth, ghatti gum, pectins, gelatin, caseinates and hydroxypropylguar, and (iii) at least one amphiphilic polymer comprising at least one fatty chain and at least one hydrophilic unit.
Abstract: Powdery pharmaceutical compositions including an active ingredient and carrier particles containing only a small amount of lubricant, 0.1-0.5% by weight, are used to prepare dry powder inhalers in order to increase the fine particle dose. A process for coating the surface of the carrier particles with such little amount of lubricant is also provided. Use of limited amount of lubricant is safe and provides ordered stable mixtures without segregation of the active particles during handling and before use.
Type:
Grant
Filed:
June 26, 2000
Date of Patent:
March 4, 2003
Assignee:
Chiesi Farmaceutical S.p.A.
Inventors:
Rossella Musa, Paolo Ventura, Paolo Chiesi
Abstract: Novel bisexual attractants for lepidopterous insect pests isolated from pears or apples. A method for monitoring and control of codling moth and other species of Lepidoptera comprising a lure and kill, mating disruption or mass trapping strategy. A method of using a formulation containing the bisexual attractants with or without an insecticide and/or pheromone for control of the insect pests.
Type:
Grant
Filed:
April 23, 2001
Date of Patent:
March 4, 2003
Assignees:
Trece, Inc., The United States of America as represented by the Secretary
of Agriculture
Abstract: The present invention relates to emulsions comprising an emulsification system comprising a mixture of at least one cationic surfactant, at least one anionic surfactant, at least one “bridging surfactant”, an oil and water, along with methods for preparing such emulsions. More specifically, the invention relates to stable, synergistic emulsions of various oils, water, cationic, anionic, and bridging surfactants that are useful in preparing a variety of finished personal care, laundry, and cleaning products, including for examples creams, lotions, sunscreens, liquid dish detergents, laundry detergents, automatic dishwasher detergents, hand soaps, laundry bars, personal cleansing bars, multi-purpose cleaners, multi-functional shampoos, body washes, and textile treatment compositions. The emulsifications of the present invention also may be employed in agricultural and pesticide applications. Additionally, the surfactant blends may be utilized in antimicrobial formulations (e.g.
Type:
Grant
Filed:
September 15, 2000
Date of Patent:
March 4, 2003
Assignee:
Stepan Company
Inventors:
Daniela T. Bratescu, Randal J. Bernhardt
Abstract: Disclosed herein are topical compositions and methods for using the same to relieve pain in humans, such as pain associated with cancer, bone injuries, old age, and many other forms of pain. Specifically, the present compositions comprise an effective amount of acetone, a salicylate-based compound and an emollient. In addition, the present compositions further comprise one or more compounds including, but not limited to, terpenes and essential oils. The present compositions may be in the form of a liquid (preferably a slightly viscous liquid) or other forms including, but not limited to, salves, creams, gels, ointments or sprays.
Abstract: A metered dose inhaler having part or all of its internal metallic surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents and one or more excipients.
Type:
Grant
Filed:
May 3, 2000
Date of Patent:
February 25, 2003
Assignee:
SmithKline Beecham Corp.
Inventors:
Ian C. Ashurst, Ignatius Loy Britto, Craig Steven Herman, Li Li-Bovet, Michael Thomas Riebe