Abstract: An implantable prosthesis and a method of attaching the prosthesis to a tissue structure disclosed. The prosthesis includes a body having a first side arranged to face the tissue structure having a defect and second side opposite the first side. One or more adhesive-filled pods are disposed on the first side of the body and selectively openable to supply an adhesive in between the tissue structure and the first side of the prosthesis body after the prosthesis body is positioned relative to the defect. The pods may be pierced, punctured, broken, and/or ruptured to supply the adhesive. A deployment device having a piercer may be used to puncture the pods.

Abstract: A device set designed for PCNL surgery includes a puncture needle, a guidewire, a dilator, a balloon catheter, a sheath, and a drainage catheter which are all placed in a single package. A tip length of the dilator is substantially the same as a tip length of the balloon catheter. The device set may include a puncture needle, a guidewire, a plurality of dilators having different sizes, a sheath, and a drainage catheter, which are all placed in a single package, wherein all the dilators have substantially the same tip length.

Abstract: Wound closure devices and methods of using the wound closure devices are disclosed. The wound closure device comprises two clips. Each clip comprises a wedge-shaped body, a tab extending from a tip of the wedge-shaped body, an anchor extending from a base of the wedge-shaped body, and a locking mechanism positioned within the wedge-shaped body.

Abstract: Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating an abrasive element within the vessel. The abrasive element can be attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly.

Abstract: Vascular filters and deflectors and methods for filtering bodily fluids. A blood filtering assembly can capture embolic material dislodged or generated during an endovascular procedure to inhibit or prevent the material from entering the cerebral vasculature. A blood deflecting assembly can deflect embolic material dislodged or generated during an endovascular procedure to inhibit or prevent the material from entering the cerebral vasculature.

Abstract: Delivery and detachment of an implant can be enhanced by a retraction mechanism to secure portions of a delivery wire within an interior space of the implant. A delivery system can include an implant having a proximal end portion. A delivery wire can include (i) a detachment zone proximal to the proximal end portion and (ii) a distal region distal to the proximal end portion. An expansion member can be located between the proximal end portion and the distal region of the delivery wire. The expansion member can be biased to move the distal region of the delivery wire distally away from the proximal end portion when severed at the detachment zone.

Abstract: An elongate endovascular element for crossing through an obstruction in a blood vessel comprises: a proximal section; a distal tip section of smaller diameter than the proximal section; and a distally-tapering intermediate section extending between the proximal and distal tip sections; wherein the tapered intermediate section has a length that is substantially ?/2 or a multiple of ?/2, where ? is a wavelength of a driving frequency that will produce longitudinal resonance in the element.

Abstract: A system for treating a bifurcated vessel that includes a first delivery catheter and a second delivery catheter. The first delivery catheter carries a proximal first stent and a distal second stent. The first delivery catheter also has a first elongate shaft, a proximal first expandable member with the proximal first stent disposed thereover, and a distal second expandable member with the distal second stent disposed thereover. The proximal first expandable member and distal second expandable member are independently expandable of one another. The second delivery catheter carries a third stent. The second delivery catheter also has a second elongate shaft, and a third expandable member with the third stent disposed thereover. The third expandable member is independently expandable of the proximal first expandable member and the distal second expandable member.

Abstract: Vascular prosthesis includes a luminal graft component defining a graft fenestration, at least one support disk fenestration, and a moveable disk defining a moveable disk opening, wherein the graft fenestration, the support disk fenestration and the moveable disk opening are all aligned, and the moveable disk is sandwiched between the support disk and the luminal graft component or between two of the support disks. The moveable disk is moveable between the support disk and the luminal graft component. The support disk is fixed to the luminal graft component. The vascular prosthesis is implanted by a method that includes directing the vascular prosthesis to an aneurysm site of a patient, and then implanting a branch prosthesis through the graft fenestration and into an arterial branch, whereby the moveable disk opening moves within the support disk fenestration to properly align the branch prosthesis with the arterial branch.

Abstract: An ultrasonic scalpel includes a scalpel body, a scalpel rod, and an ultrasonic generator, where an annular conductive part, the ultrasonic generator, and an elastic conductive part are arranged in the scalpel body; the scalpel rod is connected to an output terminal of the ultrasonic generator; and the annular conductive part and the scalpel body are connected to each other. An intermediate shell is arranged to fixedly engage with an outer side of the ultrasonic generator; a mounting hole which fits the elastic conductive part is provided in an outer side of the intermediate shell; and the elastic conductive part is electrically connected to the ultrasonic generator and the annular conductive part respectively.

Abstract: A system configured to cut leaflet tissue at a cardiac valve may comprise a guide catheter and a cutting mechanism routable through the guide catheter. The cutting mechanism includes a cutting arm and a plurality of grasping arms rotatably coupled to the cutting arm. The grasping arms are connected to the cutting arm via a central hinge and are actuatable between a closed position against the cutting arm and an open position where the grasping arms extend laterally away from the cutting arm by rotating about the hinge. Targeted cardiac leaflet tissue may be grasped between the cutting arm and the grasping arms and cut by a cutting element that is attached to or extends through the cutting arm.

Abstract: Disclosed embodiments include apparatuses, systems, and methods for driving a needle to facilitate suturing, such as may be performed in a surgical anastomosis procedure. In an illustrative embodiment, an apparatus includes a frame configured to counter-rotatably support two generally parallel rollers. A first roller supported by the frame has a flat surface configured to rollably engage a first face of a shaft of a helically-shaped needle. A second roller supported by the frame has a grooved surface defining a groove that is configured to at least partially receive a second face of the shaft. The bottom of the groove has a bottom width at least as wide as the second face and bounded by sides extending to a groove opening at the grooved surface having a surface width that is wider than the second face.

Abstract: A medical device and methods for altering lung volume are disclosed. The medical device includes a coil formed of a biodegradable material including a first bioabsorbable material that is configured to deactivate a portion of a lung as the coil degrades. The method includes positioning a first coil adjacent a first target within a patient and permitting the first coil to degenerate such that a first bioabsorbable material deactivates a first portion of a lung. The first coil is formed of a biodegradable material and includes the first bioabsorbable material.

Abstract: Medical devices as well as methods for making and using medical devices are disclosed. An example medical device may include a steerable crossing catheter system. The steerable crossing catheter system may include an elongate catheter shaft having a proximal end region, a steerable distal end region, and a lumen extending therethrough. A core may be disposed within the lumen. The core may have a distal end. A penetrating member may be coupled to the distal end. A sensing assembly may be disposed adjacent to the distal end. The sensing assembly may be configured to estimate the location of the core within a body lumen.

Abstract: Devices, systems for localized delivery of a chemotherapy, hormonal therapy or targeted drug/biologic therapy to a target tissue area of an internal body organ of a patient. A catheter 10 forms a sealed treatment chamber in a natural lumen extending through the target tissue area. Air is purged from the chamber, which is then filled with a liquid drug solution for an adequate treatment session time, solution volume and drug concentration to saturate the target tissue area, thereby providing the treatment. The liquid drug solution may be circulated or recirculated through the chamber or maintained stationary therewithin. The drug may saturate the target tissue area and pass therethrough into the lymphatic system or interstitial space, which may serve as a reservoir of the drug for continued therapeutic treatment after withdrawal of the catheter. The chamber is evacuated at the end of the treatment session.

Abstract: A fluid flow metal sleeve includes a sleeve main body and an elongation portion, which are of a hollow structure as a whole. The sleeve main body is connected to the elongation portion in a threaded manner, and a terminal end of the sleeve main body is connected to an ultrasound scalpel handle and enables an ultrasound scalpel to pass therethrough. The fluid flow metal sleeve can control the direction of fluid flow during incision with the ultrasound scalpel so as to achieve the lubricating and cooling effects on a scalpel head. In addition, due to the use of a metal structure, a user can extend an original holding part from an outer portion of the ultrasound scalpel handle to an outer wall of the metal sleeve as required. The fluid flow metal sleeve also has an adjustable telescopic function so as to be adapted to different application scenarios, and limits the length of extension of the scalpel head so as to limit the depth during incision to improve the safety of surgery.

Abstract: A band for surgical wound suture includes a first band having a first left band and a first right band and a second band located above the first band and having a second left band and a second right band, in which the first left band is connected to the second right band, and the second right band is connected to the first left band. The band for surgical wound suture provides advantages that an incision may be sutured by a simple operation of pulling the left and right bands to the left and right and attaching them, a feeling of heterogeneity after a suturing procedure may be minimized with a suturing device having a small volume and having almost no hard parts, and furthermore, the incision may be joined and firmly fixed by a wide and sturdy joint joined to both sides of the incision.

Abstract: In one example, a medical device may be adapted for use with a delivery device, and the medical device may include a handle including at least one actuator; a body adapted to releasably mount to a distal portion of the delivery device, the body supporting a pair of jaws rotatably coupled to the body; and a control wire coupled to the pair of jaws and the actuator. The actuator may be configured to open and close the pair of jaws.

Abstract: A modular dilation device is provided for inserting multiple dilators into a target patient tissue site. The modular dilation device includes a first dilator and a second dilator. The first dilator has a first dilator distal end and a first dilator inner lumen. The first dilator has a first dilator side wall opening. The first dilator distal end has a first dilator open tip. The first dilator has a first dilator open slit. The first dilator open slit extends between the first dilator side wall opening and the first dilator open tip. The second dilator has a second dilator distal end and a second dilator inner lumen. The second dilator distal end has a second dilator open tip. When the second dilator is joined to the first dilator, the second dilator open tip is adjacent to the first dilator side wall opening.

Abstract: The present invention relates to a reflux disease treatment apparatus, comprising two or more movement restriction device segments adapted to form an implantable movement restriction device with an elongated shape that maintains cardia in the correct position. The movement restriction device has proximal and a distal end, wherein the distal end is adapted to stabilize and hold the proximal end. The invention further comprises a control device for controlling the stimulation device to stimulate the cardia sphincter. The distal end can be further adapted to treat obesity, for example by stretching the wall of the stomach or filling out a volume of the stomach.