Patents Examined by Katherine Zalasky
  • Patent number: 10370275
    Abstract: A system includes an ion exchange softener fluidly coupled to a wastewater treatment system. The first ion exchange softener may receive a first brine stream from the wastewater treatment system and to remove a plurality of minerals from the first brine stream to generate a second brine stream including the plurality of minerals and a third brine stream. The system also includes a mineral removal system disposed downstream from the ion exchange softener and that may receive the second brine stream and to generate a sodium chloride (NaCl) brine stream and an acid and caustic production system disposed downstream from and fluidly coupled to the mineral removal system. The acid and caustic production system includes a first electrodialysis (ED) system that may receive the NaCl brine stream from the mineral removal system and to generate hydrochloric acid (HCl) and sodium hydroxide (NaOH) from the NaCl brine stream.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: August 6, 2019
    Assignee: Enviro Water Minerals Company, Inc.
    Inventor: Paul Steven Wallace
  • Patent number: 10324070
    Abstract: A system, module and method for continuous or batch single-pass countercurrent tangential chromatography are disclosed for bind/elute and negative chromatography applications. The system includes binding, washing, elution (for bind/elute), regeneration, and equilibration single-pass modules. The resin slurry flows in a continuous single pass at steady-state through each module, while corresponding buffers flow countercurrent to the slurry facilitating efficient product and impurity extraction. The module and system include retentate pumps for better process robustness and control. A resin tank configured to be reversibly isolated from the single-pass modules facilitates a closed and disposable system.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: June 18, 2019
    Assignee: CHROMATAN INC.
    Inventor: Oleg Shinkazh
  • Patent number: 10315163
    Abstract: Separation processes using engineered osmosis are disclosed generally involving the extraction of solvent from a first solution to concentrate solute by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane. Enhanced efficiency may result from using low grade waste heat from industrial or commercial sources.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: June 11, 2019
    Assignee: Oasys Water LLC
    Inventors: Robert L. McGinnis, Joseph Edward Zuback
  • Patent number: 10315936
    Abstract: Separation processes using engineered osmosis are disclosed generally involving the extraction of solvent from a first solution to concentrate solute by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane. Enhanced efficiency may result from using low grade waste heat from industrial or commercial sources.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: June 11, 2019
    Assignee: Oasys Water LLC
    Inventors: Robert L. McGinnis, Joseph Edward Zuback
  • Patent number: 10317377
    Abstract: Provided herein are methods of liquid column chromatography in which preparative chromatography is performed in-line with analytical chromatography. In particular aspects a monolithic preparative column is used to purify an analyte of interest from a mixture of other substances by applying the mixture to the column, reversing the flow through the column to elute the analyte, which is applied to an analytical column provided in-line with the preparative column. In other aspects, a single monolithic column is used to perform both the preparative chromatography and analytical chromatography steps in succession. In another aspect, a chromatography system is provided to perform preparative and analytical chromatography using a single monolithic column.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: June 11, 2019
    Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED
    Inventors: Nigel Clarke, Mildred M. Goldman
  • Patent number: 10307692
    Abstract: A chromatography column including: a tubular housing; a first end unit removably connected to a first end of the tubular housing; a second end unit removably connected to a second end of the tubular housing; an adaptor assembly movable within said tubular housing; an adaptor rod connected to said adaptor assembly, which adaptor rod is arranged to extend through an opening in the first end unit; a filter removably connected to the adaptor assembly; and a frame connected to said tubular housing for supporting the column on a floor. At least an actuating means is arranged on the frame, so that the column can be lifted and lowered in a substantially vertical direction.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: June 4, 2019
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Stefan Kjell Eriksson, Andreas Bergstrom
  • Patent number: 10287202
    Abstract: The disclosure relates to an apparatus, system, and methodology for treating nested waste matter, including a delivery system for delivering a volume of untreated material; a confined container having an inlet connected to the delivery system; an energy impingement device introduced transversely into said confined container, where the energy impingement device is configured to deliver a volume of injected fluid and further configured to treat the volume of untreated material in said confined container and wherein the confined container has an outlet for exiting a volume of treated material.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: May 14, 2019
    Inventor: John E. Powell, Jr.
  • Patent number: 10286363
    Abstract: Components, systems, and methods for producing highly hydrophilitic, functionalized inorganic filtration membranes, pre-treating organic and biological-containing waste waters for minimal membrane fouling and scaling when processed using such functionalized membranes, and use of such functionalized membranes of the present invention in filtration systems for separating such pre-treated waste waters, all with respect to optimal permeate production rates, purity of permeate and resistance to fouling and scale formation on the membranes.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: May 14, 2019
    Assignee: LANCE ENERGY SERVICES, LLC
    Inventors: Waymon R. Votaw, Jacob L. Davis, Edward E. Munson, Andrew R. Barron, Samuel J. Maguire-Boyle
  • Patent number: 10280196
    Abstract: In one aspect, affinity tags for recombinant protein purification are described herein which, in some embodiments, can mitigate or overcome disadvantages of prior affinity tag systems. In some embodiments, for example, affinity tags described herein permit efficient elution of desired recombinant proteins with simplified solution systems, such as alkali metal salt solutions. An affinity tag described herein comprises an amino acid sequence including a repeating amino acid unit of BXXXBXX, wherein B is an amino acid selected from the group consisting of histidine, lysine and arginine and X is an amino acid selected from the group consisting of amino acids other than histidine, lysine and arginine.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: May 7, 2019
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
    Inventors: Suresh Kumar Thallapuranam, Srinivas Jayanthi, Jacqueline Morris, Alicia Brown, David McNabb, Ralph Henry
  • Patent number: 10280195
    Abstract: Methods are provided for enhancing reduction of virus and viral DNA levels in protein preparations.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: May 7, 2019
    Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventor: Peter Stanley Gagnon
  • Patent number: 10273198
    Abstract: A solvent exchanger and a method is provided for: pressurizing a CTA slurry into a solvent exchanger for separation and obtaining a mother liquor, a bias flow mother liquor and a suspended matter A; washing the suspended matter A to obtain a primary filtrate, a bias flow primary filtrate and a suspended matter B; washing the suspended matter B to obtain a secondary filtrate, a bias flow secondary filtrate and a suspended matter C; washing the suspended matter C to obtain a tertiary filtrate, a bias flow tertiary filtrate and a suspended matter D; washing the suspended matter D to obtain a fourth filtrate, a bias flow fourth filtrate and a suspended matter E; washing the suspended matter E to obtain a fifth filtrate, a bias flow fifth filtrate and a filter cake; and after finished, back-flushing the filter cake and then pulping to obtain a slurry, and discharging.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: April 30, 2019
    Assignee: TIANHUA INSTITUTE OF CHEMICAL MACHINERY AND AUTOMATION CO., LTD
    Inventors: Xu Zhao, Wanyao Zhang, Zhongxin Sun, Yongpeng Tan, Xiangnan Zhai, Tianbao Wang, Yuanyue Liang, Guohai Zhang, Xiaopeng Feng, Yanshun Shen
  • Patent number: 10265644
    Abstract: An enantioselective zwitterionic ion-exchange material comprising a chiral selector component (SO) comprising at least one cation exchange group and at least one anion exchange group and a carrier, carrying said selector component, wherein the chiral selector component comprises at least one chiral linker moiety to connect said ion exchange groups in a non-macrocyclic fashion, and said chiral linker moiety contains at least one ?-? interaction site.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: April 23, 2019
    Assignee: UNIVERSITAET WIEN
    Inventors: Wolfgang Lindner, Michael Laemmerhofer, Christian Hoffman
  • Patent number: 10265453
    Abstract: An artificial, extracorporeal system for liver replacement and/or assistance, comprises a liver dialysis device for conducting hemodialysis on a patient suffering from liver failure. The liver dialysis device comprises a first standard hollow fiber membrane dialyzer which does not allow passage of an essential amount of albumin over the membrane wall and which is perfused with the patient's blood, and a second hollow fiber membrane dialyzer which allows the passage of essential but defined amounts of albumin over the membrane wall and which receives the blood of the first standard hemodialyzer. The filtrate space is closed off from the lumen space of the hollow fibers and is populated by adsorbent material which may comprise one or more different adsorbents.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: April 23, 2019
    Assignee: GAMBRO LUNDIA A.B.
    Inventors: Ralf Flieg, Stephan Aldinger, Markus Storr, Bernd Krause
  • Patent number: 10258903
    Abstract: A method for chromatographically separating a first saccharide from a liquid eluent comprising the first saccharide and a second saccharide by passing the liquid eluent through a bed including a polymeric macroporous alkylene-bridged resin in calcium form.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: April 16, 2019
    Inventors: Daryl J. Gisch, Christopher R. Eicher, Stephen Pease, Gongwei Pu
  • Patent number: 10252186
    Abstract: In a solid phase extraction (SPE) apparatus, a cartridge housing tray houses a plurality of SPE cartridges. A liquid loading assembly applies liquid samples and SPE solutions into the plurality of cartridges. A liquid drawing assembly forces the liquid samples and the SPE solutions once they are applied to pass through the plurality of the SPE cartridges.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: April 9, 2019
    Assignee: ZIST ABZAR PAJOOHAN
    Inventor: Seyed Kamal Fatemi
  • Patent number: 10254229
    Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: April 9, 2019
    Assignee: OndaVia, Inc.
    Inventors: Mark C. Peterman, Merwan Benhabib, Samuel Kleinman
  • Patent number: 10252227
    Abstract: A system and an associated method for starting up stirring machines in a sediment in a controlled manner are provided, which system has the following: a container for receiving materials to be processed; a stirring device with stirring blades for stirring the materials to be processed in the container; a purging device; and a device for operating stirring machines. The purging device is arranged in such a way and set up so as to feed a medium for purging to a deposited sediment. Furthermore, a controller is provided which initiates controlled re-starting of stirring machines after purging.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: April 9, 2019
    Assignee: EKATO Ruehr- und Mischtecnik GmbH
    Inventors: Jochen Jung, Wolfgang Keller
  • Patent number: 10247673
    Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: April 2, 2019
    Assignee: OndaVia, Inc.
    Inventors: Mark C. Peterman, Merwan Benhabib, Samuel Kleinman
  • Patent number: 10232287
    Abstract: An apparatus for use in a liquid chromatography system includes a chromatography port and a tubing assembly having a chromatography tube coupled at one end to the chromatography port. The end of the tube has an end face covered with a corrosion-resistant material, for example, gold. The corrosion-resistant nature of the material protects the end of the tube from corrosion or erosion, which improves the quality and reliability of a seal between the end face of the tube and a sealing surface of the port. Alternatively, or in addition to covering the end face of the tube with the corrosion-resistant material, a gasket covered with or made of the corrosion-resistant material can be disposed between the end face of the tube and the port. This gasket extends the reach of the tube to facilitate bottoming out the tube within the port.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: March 19, 2019
    Assignee: WATERS TECHNOLOGIES CORPORATION
    Inventors: Kurt D. Joudrey, Steven D. Trudeau, Paul Keenan, Joseph A. Luongo, Daniel J. McCormick, Eugene Berthiaume
  • Patent number: 10226740
    Abstract: A method of producing desalinated water and recovering minerals from the feedwater uses membrane separation and electrodialysis brine concentration. This process can recover all of the minerals as high purity industrial minerals, including capturing the calcium and sulfate as agricultural grade gypsum and boron as high purity boric acid. In addition the process allows the use of low cost lime or dolime to produce valuable magnesium hydroxide.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: March 12, 2019
    Assignee: HL Seawater Holdings, LLC
    Inventor: Paul Steven Wallace