Abstract: The invention provides methods and compositions relating to polypeptide activators of caspases such as polypeptide and polynucleotide sequences diagnostic of caspase activators. These sequences, and polypeptides and polynucleotides embodying these sequences, find a wide variety of diagnostic and therapeutic applications involving detecting and/or modulating expression and/or function of activators or caspases or genes or transcripts encoding such activators and generating genetic and immunogenic probes specific to activators of caspases.
Type:
Grant
Filed:
January 6, 2000
Date of Patent:
August 29, 2000
Assignee:
Board of Regents, The University of Texas System
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