Abstract: A contact detection system is configured to classify each pixel in a plurality of pixels included in an ultrasound image captured by an ultrasound probe located within a patient as either showing tissue or showing non-tissue; determine an average pixel classification representative of a number of pixels classified as showing tissue compared to a number of pixels classified as showing non-tissue; determine, if the average pixel classification is above a first contact state threshold, that the ultrasound probe is in a first contact state that indicates that the ultrasound probe is in operative physical contact with the tissue; and determine, if the average pixel classification is below a second contact state threshold lower than the first contact state threshold, that the ultrasound probe is in a second contact state that indicates that the ultrasound probe is not in operative physical contact with the tissue.

Abstract: A system and method for promoting and safeguarding the wellbeing of patients in relation to a fluid injection may obtain patient data; determine, based on the patient data, an initial risk prediction for a patient for a fluid injection to be administered to the patient, the initial risk prediction including a probability that the patient experiences at least one adverse event in response to the fluid injection; provide, to a user device, before the fluid injection is administered to the patient, the initial risk prediction; determine, after the fluid injection is started, sensor data associated with the patient; determine, based on the sensor data determined after the fluid injection is started, a current risk prediction including a probability that the patient experiences the at least one adverse event in response to the fluid injection; and provide, to the user device, the current risk prediction.

Abstract: A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

Abstract: Disclosed herein is an uroflowmeter which includes: a sensor having a signal transmitter transmitting an input signal to a detection area and a signal receiver receiving an echo signal reflected from urine passing through the detection area; a signal processing unit calculating uroflowmetry data based on a difference between the input signal and the echo signal, the uroflowmetry data being data about a flow of the urine passing through the detection area; and a diagnosis unit diagnosing urinary disorders of a test subject by comparing the uroflowmetry data calculated by the signal processing unit with preset reference uroflowmetry data.

Abstract: In an embodiment a pulse sensor includes two light sources configured to emit light in a direction of a perfused tissue of a living being so that the perfused tissue scatters the light and so that the scattered light is modulated on basis of a pulse of the living being, at least one luminescent concentrator including an entry face, an exit face smaller than the entry face, and a fluorescent material arranged in a light path between the entry face and the exit face, wherein the luminescent concentrator is configured to receive at least some of the modulated scattered light entering through the entry face, convert the entered light by the fluorescent material and emit the modulated converted light from the exit face, and one light detector configured to detect at least some of the modulated converted light emerging from the exit face, wherein, in plan view, the luminescent concentrator is strip-shaped and extends perpendicular to a connecting line between the two light sources, wherein side faces of the lumines

Abstract: A system for precisely locating abnormal areas of brain fiber bundles. The system extracts fiber connections of the whole brain from diffusion magnetic resonance data, and fiber bundle pathways extracts through self-defined fiber bundle pathways or based on brain fiber bundle templates. A selected fiber bundle pathway is projected on a fiber connection result of the whole brain and finely segmented. The imaging indexes such as fractional anisotropy, mean diffusivity, intra-neurite volume fraction and orientation dispersion index are calculated from diffusion magnetic resonance data, so as to obtain the imaging index of each node of each fiber bundle pathway. These imaging indexes are configured to classify the disease group and the healthy group by a machine learning method, and which nodes on which fiber bundle pathways have abnormal changes with different diseases can be precisely located.

Abstract: Apparatus, systems, and methods for comparative analysis of tissue and organ scans between patients or groups of patients without sensitivity to patient-specific or scanner specific characteristics, including prediction, diagnosis, prognosis, tracking, and treatment guidance are disclosed. Blood oxygen level dependent (BOLD) fMRI is performed on a patient, and the resulting structural and functional data is preprocessed to remove artifacts and correct motion defects. A BOLD value is selected from the Vein of Galen as the maximum anatomically plausible intensity and from the Middle Cerebral Artery as the minimum anatomically plausible intensity. The maximum and minimum intensities are used to normalize the BOLD data and generate a neurovascular coupling statistical map of the brain.

Abstract: An apparatus and a method for detecting heartbeat include a sensor configured to detect displacements of an object without contacting the object wherein the object displaces corresponding the a human's heartbeat, a data processing unit configured to extract a feature dataset from the detected displacement data, and a neural network configured to inference inter beat intervals from the extracted feature dataset using a pre-trained model.

Abstract: A system may transform sensor data from a sensor domain to an image domain using data-driven manifold learning techniques which may, for example, be implemented using neural networks. The sensor data may be generated by an image sensor, which may be part of an imaging system. Fully connected layers of a neural network in the system may be applied to the sensor data to apply an activation function to the sensor data. The activation function may be a hyperbolic tangent activation function. Convolutional layers may then be applied that convolve the output of the fully connected layers for high level feature extraction. An output layer may be applied to the output of the convolutional layers to deconvolve the output and produce image data in the image domain.

Abstract: The disclosure relates to magnetic resonance imaging triggered by a prospective acquisition correction sequence. The technique comprises determining repetition time and an acquisition window time of a single-shot fast spin echo sequence; determining the maximum imaging layer number N in each physiological movement cycle on the basis of the acquisition window time and the repetition time, where N is a positive integer greater than or equal to 2; and enabling the single-shot fast spin echo sequence to obtain M layers of imaging data within at least one acquisition window time when the prospective acquisition correction sequence generates a trigger signal, where M is a positive integer greater than or equal to 2 and less than or equal to N. According to the present disclosure, a plurality of layers of imaging data are obtained within a single acquisition window time, thereby increasing a scanning speed and shortening imaging time.

Abstract: A method for detecting blood-tissue barrier breakdown or disruption is provided. The method includes acquiring first image data of a target region of a subject with a predetermined spatial resolution; administrating exogenous or endogenous tracer into the subject; acquiring second image data of the target region with the predetermined spatial resolution after administration of the tracer; differentiating healthy tissue and pathological tissue with blood-tissue barrier breakdown in the target region based on the first image data and the second image data; and visualizing or analyzing the blood-tissue barrier breakdown of pathological tissue based on the differentiation.

Abstract: A method of discovering relationships between iris physiology and cognitive states and/or emotional states of a subject includes providing a computing device and a video camera to record a close-up view of the subject's eye. A first light is held to the lower eyelid skin and a second light a distance away illuminating the stroma of the eye. The first and second light are electronically synced together and configured to flash alternatively. The user engages in a plurality of tasks while recording ocular information which is processed to identify correlations between the responses in the iris musculature and the distortions in the stroma through the use optimized algorithms. One can then identifying at least one predictive distortion is identified in the stroma capturable solely with a visible-spectrum camera correlating to a predicted responses in the iris musculature.

Abstract: Systems and methods are provided for producing an image of a subject using a magnetic resonance imaging (MRI) system. The method includes designing a saturation-based labeling pulse sequence for an MRI process that includes radio-frequency (RF) pulses and gradients forming a ratio of RF slice-selection gradient to time-averaged gradient that maintains multiple aliased labeling planes within an envelope of the RF pulses. The method also includes performing the MRI process to acquire image data from the subject using the saturation-based labeling pulse sequence and reconstructing a saturation-based spin labeled images of the subject using image data.

Abstract: Systems and methods are provided for evaluating a patient for a neurological movement disorder. A three-dimensional medical image of a brain of the patient is captured and provided to an artificial neural network having at least one convolutional layer to provide a set of output values. The set of output values is provided to a machine learning model to provide a clinical parameter representing one of a presence of the neurological movement disorder in the patient and a response of the patient to a specific treatment for the neurological movement disorder.

Abstract: The present invention relates to a therapeutic ultrasound generation device, and a handpiece for ultrasound treatment including same. The therapeutic ultrasound generation device comprises: a cartridge housing unit; an ultrasonic transducer unit that is located in the cartridge housing unit, is disposed inclined with respect to a rotational central axis direction, and generates ultrasonic waves in the inclined direction; an inclined block unit that is located in the cartridge housing unit, has an inclined surface on the lower surface thereof, and supports the upper surface of the ultrasonic transducer unit such that the ultrasonic transducer unit is inclined with respect to the rotational central axis direction; and a rotating motor that rotates the inclined block unit. The therapeutic ultrasound generation device simplifies the structure of moving the focal point of the ultrasonic waves, generated by the ultrasonic transducer unit, in a circular shape on the same plane.

Abstract: This instant disclosure provides a heart rate detecting device which includes an image sensor. The image sensor generates a first mixed signal within a first interval and generates a second mixed signal within a second interval, wherein the first mixed signal contains light information of first multiple light wavelengths having a first intensity ratio from one another, and the second mixed signal contains light information of second multiple light wavelengths having a second intensity ratio, different from the first intensity ratio, from one another.

Abstract: A system and method may be used to position or orient a camera within a surgical field. A method may include generating a graphical user interface including a first set of instructions to reposition the camera, and determining whether the camera is within a target volume location. The method may include automatically outputting an indication when the camera is within the target volume location. The method may include outputting a second set of instructions for display on the graphical user interface to align a laser, coupled to or integrated into the camera, to the tracker by changing an angle of the camera.

Abstract: A wearable treatment and analysis module is provided. The module is positioned on or near a body surface region of interest. The module provides remote access to sensor data, treatment administration, and/or other health care regimens via a network connection with a user device and/or management system.

Abstract: An apparatus and method for non-invasive and continuous measurement of respiratory chamber volume and associated parameters including respiratory rate, respiratory rhythm, tidal volume, dielectric variability and respiratory congestion. In particular, a non-invasive apparatus and method for determining dynamic and structural physiologic data from a living subject including a change in the spatial configuration of a respiratory chamber, a lung or a lobe of a lung to determine overall respiratory health comprising an ultra wide-band radar system having at least one transmitting and receiving antenna for applying ultra wide-band radio signals to a target area of the subject's anatomy wherein the receiving antenna collects and transmits signal returns from the target area.

Abstract: An MR Spectroscopy (MRS) system and approach is provided for measuring spectral information corresponding with propionic acid (PA), either alone or in combination with other measurements corresponding with other chemicals, to diagnose and/or monitor at least one of bacterial infection, such as associated with P. acnes, or conditions related thereto such as nociceptive pain associated with tissue acidity. An interfacing DDD-MRS signal processor receives output signals to produce a post-processed spectrum, with spectral regions corresponding with certain chemicals, including PA, then measured as biomarkers. A diagnostic processor derives a diagnostic value for each disc, and performs certain normalizations, based upon ratios of the spectral regions related to chemicals implicated in degenerative painful tissue pathology, such as PA and hypoxia markers of lactic acid (LA) and alanine (AL), and structural chemicals of proteoglycan (PG) and collagen or carbohydrate (CA).