Abstract: The present disclosure is directed to systems and methods for generating images using short tau inversion recovery, ultrashort echo time (STIR-UTE) MRI sequences. The STIR-UTE MRI sequences can be used to generate images that can differentiate between regions that are at temperatures that are either lethal or non-lethal to cell life. Thus, these sequences can be beneficial for implementations such as in monitoring cryoablation procedures.

Abstract: Described herein are implantable devices configured to emit an electrical pulse. An exemplary implantable device includes an ultrasonic transducer configured to receive ultrasonic waves that power the implantable device and encode a trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit. Also described are systems that include one or more implantable device and an interrogator configured to operate the one or more implantable devices. Further described is a closed loop system that includes a first device configured to detect a signal, an interrogator configured to emit a trigger signal in response to the detected signal, and an implantable device configured to emit an electrical pulse in response to receiving the trigger signal.

Abstract: An non-Doppler flow imaging system is disclosed that overlays a B-flow imaging sequence over B-mode ultrasound image data.

Abstract: The present disclosure provides techniques for determining a respiration phase by extracting a distance characteristic value, a score characteristic value, and an area characteristic value from the respiration signal, wherein the distance characteristic value, the score characteristic value and the area characteristic value are used to indicate waveform variation between two adjacent waveforms in the respiration signal. The techniques include training a respiration signal model according to the distance characteristic value, the score characteristic value, and the area characteristic value to determine the respiration phase of the respiration signal using the respiration signal model.

Abstract: A surgical system used to determine the presence of a vessel within a region (102) proximate to a working end (104) of a surgical instrument (106) includes at least one light emitter (110) disposed at the working end (104) of the surgical instrument (106), and at least one light sensor (112) disposed at the working end (104) of the surgical instrument (106) and configured to receive light emitted from the at least one light emitter (110) and reflected from the region (102), the at least one light sensor (112) adapted to generate a signal comprising a first pulsatile component and a second non-pulsatile component.

Abstract: A needle electrode deployment shaft includes a central member and a plurality of needle electrodes. The central member has a plurality of needle advancement channels formed therein. The needle electrodes are disposed within the advancement channels and each advancement channel terminates in a ramp portion which deflects the needles radially outwardly as they are axially advanced. The ramps may be spirally or acutely configured in order to increase the distance through which the needles may be bent as they are axially advanced. Additionally, the central member may have a radially reduced distal tip in order to decrease tissue insertion forces.

Abstract: There is provided a computer implemented method of reconstructing an image of a body cavity shape of a subject based on a plurality of location indications, indicating locations of at least one sensor disposed on an intrabody probe within the body cavity, the method comprising: receiving data indicative of the plurality of location indications, identifying based on the data at least a first group and a second group of location indications, and reconstructing the body cavity from the data, using a first reconstruction method for the first group of location indications, and a second reconstruction method for the second group of location indications.

Abstract: Aspects of the disclosure are directed to methods and/or apparatuses involving modifying flow and/or concentration of an agent being injected for characterizing a vascular system. As may be implemented in accordance with one or more embodiments, a liquid including an agent is injected into a vascular system, by dynamically modulating a flow rate of the agent being injected over a range of flow rates. The vascular system is characterized based on a response of the vascular system to the dynamic modulation. In some implementations, such an approach involves using an injector that operates to separately control the rate at which an agent and other liquid such as saline are injected. These approaches can be implemented with modulation schemes using one or more of a variety of functions.

Abstract: A processor acquires a radiographic image including a human body and a surgical tool image which indicates a surgical tool and is acquired by a method other than radiography. The processor combines the surgical tool image with the radiographic image to generate a training image for training a discriminator that discriminates a region of the surgical tool in a target image in a case in which the target image is input.

Abstract: A method for generating a perfusion weighted image using arterial spin labeling (ASL) with segmented acquisitions includes dividing an anatomical area of interest into a plurality of slices and performing a multi-band (MB) echo planar imaging (EPI) acquisition process using a magnetic resonance imaging (MRI) system to acquire a control image dataset representative of the plurality of slices using a central-to-peripheral or peripheral-to-central slice acquisition order. An ASL preparation process is performed using the MRI system to magnetically label protons in arterial blood water in an area upstream from the anatomical area of interest. Following a post-labeling delay time period, the MB EPI acquisition process is performed to a labeled image dataset corresponding to the slices using the central-to-peripheral or peripheral-to-central slice acquisition order. A perfusion weighted image of the anatomical area is generated by subtracting the labeled image dataset from the control image dataset.

Abstract: A method is provided to model a 3D structure comprising: producing a surface mesh representation of the 3D structure; producing a volume mesh representation of the 3D structure based upon the surface mesh; sorting vertices of the volume mesh into a first sub-list that includes only surface vertices and a second sub-list that includes only internal vertices; applying shading to the surface mesh by accessing only surface vertices in the first sub-list; determining deformation of the volume mesh by accessing both surface vertices in the first sub-list and internal vertices in the second sub-list.

Abstract: An analysis method and an electronic apparatus for breast image are provided. The method includes the following steps. One or more breast ultrasound images are obtained. The breast ultrasound images are used for forming a three-dimensional (3D) breast model. A volume of interest (VOI) in the breast ultrasound image is obtained by applying a detection model on the 3D breast model. The VOI is compared with a tissue segmentation result. The VOI is determined as a false positive according to a compared result between the VOI and the tissue segmentation result. The compared result includes that the VOI is located at a glandular tissue based on the tissue segmentation result. In response to the VOI being located in the glandular tissue of the tissue segmentation result, the VOI is compared with the lactiferous duct in the 3D breast model.

Abstract: The present invention describes a new functional biomarker of vascular inflammation and its use in predicting all-cause or cardiac mortality. The invention also provides a method for stratifying patients according to their risk of all-cause or cardiac mortality using data gathered from a computer tomography scans of a blood vessel to determine a specific combination of structural and functional biomarkers of vascular inflammation and disease.

Abstract: A multi-angular ultrasound device. Multi-angular ablation patterns are achieved by a catheter-based ultrasound transducer having a plurality of transducer zones. A multi-chambered balloon is positioned on the catheter.

Abstract: An ultrasonic blood flow imaging display method and an ultrasonic imaging system. The system comprises: a probe (1); a transmitting circuit (2), configured to excite the probe (1) to transmit an ultrasonic beam to a scanning target; a receiving circuit (4) and a beam forming module (5), configured to receive an echo of the ultrasonic beam to obtain an ultrasonic echo signal; a data processing module (9), configured to obtain, according to the ultrasonic echo signal, blood flow velocity vector information and Doppler blood flow velocity information about a target point in the scanning target and at least part of ultrasonic images of the scanning target, and superposing the ultrasonic images and the Doppler blood flow velocity information to form a Doppler color blood flow graph; and a display (8), configured to contrastively display the blood flow velocity vector information and the Doppler color blood flow graph.

Abstract: A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images.

Abstract: A magnetic marker for use in locating tissue for surgery includes a casing and two to five magnetic elements arranged in a row. The two or more magnetic elements are separated from each other by an isolating material. The magnetic marker may be non-bio-absorbable. This means that the magnetic marker is invariable as it does not decay over time. This invariability ensures that on the basis of the signal measured by a magnetometer device a distance between a probe of the magnetometer device and the magnetic marker can be determined.

Abstract: Tracked mobile x-ray imaging equipment is used to produce single or stereo long calibrated views of the anatomy of a patient on the operating table. The system estimates the position and orientation of the anatomical planes, virtually places measurement grids over these reference planes, and transforms any radiographic views taking by the x-ray imaging system onto these calibrated planes. The system may apply information about the depth of the anatomy to remove parallax artifacts. This system enables displaying and evaluation of the entire radiographic length of the anatomical planes using a mobile x-ray equipment. It also provides a platform for overlaying the real time x-ray images taken during operation with radiographic images of the patient or schematic of the surgical plan developed before the surgery for quick evaluation of a surgical plan.

Abstract: A method for determining movement of an object to be imaged in a medical imaging method which includes at least one Magnetic Resonance Imaging, wherein the method comprises the following steps determining first coefficients of a mathematical transformation based on first navigator data of the object, wherein the first navigator data are recorded by a magnetic resonance tomograph (100) using a first spherical Lissajous navigator in the k-space with kr<0.2/cm, preferably kr<0.15/cm, and particularly preferably kr<0.1/cm, wherein kr represents the absolute value of the wave vector k.

Abstract: Ingestible devices are disclosed that provide very high localization accuracy for the devices when present in the GI tract of a body. Related systems and methods are also disclosed.