Abstract: In one embodiment, the present invention provides an implantable stimulation device that includes output current sources and/or sinks configured to provide an output current for a load (i.e., tissue). The output path of the output current source or sink comprises a transistor which operates in a linear mode instead of a saturation mode. Because operation in a linear mode results in smaller drain-to-source voltage drops, power consumption in the output current source or sink (and hence in the implantable stimulator) is reduced, reducing battery or other power source requirements. Operation in the linear mode is facilitated in useful embodiments by a load in an input path (into which a reference current is sent) and a load in the output path (which bears the output current). The loads can be active transistors or passive resistors. A feedback circuit (e.g.

Abstract: An apparatus includes an implant delivery device configured to deliver an implant into a body. The implant delivery device includes a target member, an insertion member and an electronic circuit system. The target member has a distal end portion configured to be disposed within the body adjacent a target location. The insertion member is movably coupled to the target member. A distal end portion of the insertion member is configured to be disposed within the body and selectively coupled to the implant. The electronic circuit system is configured to produce an electronic signal in proportion to a distance between the distal end portion of the target member and the distal end portion of the insertion member when the target member and the insertion member are disposed within the body.

Abstract: An apparatus that comprises at least one electrode adapted to be placed adjacent to a portion of smooth muscle (200) and a controller for electrifying the electrode with a non-excitatory electric field (210) which does not generate excitation of the smooth muscle. The non-excitatory electric field affects the activity of the smooth muscle in a manner that controls a level of a chemical in the blood stream.

Abstract: A connector for an electrostimulation lead includes a connector housing defining a fastener aperture, a septum disposed over the fastener aperture, and a fastener for mating with the fastener aperture to secure a received lead to the connector housing so that at least one terminal disposed on the received lead electrically couples with at least one conductor contact disposed in the connector housing. The septum includes a septum flap and an attachment cuff. The septum flap is configured and arranged for extending over the fastener aperture and for receiving a tool for folding the septum flap open to expose the fastener aperture. The attachment cuff is configured and arranged for coupling the septum flap to the connector housing. The fastener is configured and arranged to be disposed in the fastener aperture and to be tightened against the lead to hold the lead within the connector housing.

Abstract: The invention relates to a method, equipment implementing the method, and a computer software product, the method generating exercise instructions for a physical exercise. The method comprises determining the standard condition value of a heart rate parameter in a user-specific performance monitor by measuring the user's heart rate wherein the standard condition value of the heart rate parameter is a function of the standard condition value of the heart rate variation; performing comparison between the standard condition value of the heart rate parameter and a standard condition reference value of the heart rate parameter; and generating exercise instruction information for at least one future physical exercise on the basis of the comparison.

Abstract: An example relates to a method for sensing a pulmonary artery pressure (PAP) and providing a sensed PAP signal, detecting an abnormal blood pressure (BP) condition using information from the sensed PAP signal, delivering a pacing energy to a heart, and automatically altering at least one pacing characteristic in response to the detected abnormal BP condition. The detecting an abnormal BP condition can include detecting various forms of hypertension or hypotension. The automatically altering the at least one pacing characteristic can include automatically altering at least one of a pacing rate, a pacing waveform, an atriventricular (AV) delay, an interventricular (VV) delay, a pacing mode, or a pacing site. The method can also include delivering vagal nerve stimulation and automatically altering the vagal nerve stimulation in response to the detected abnormal BP condition. The detecting the abnormal BP condition can also include using a sensed auxiliary physiological parameter.

Abstract: Power supplied to a particular telemetry system of an implantable device having multiple telemetry systems is managed by a state machine. Power to a transceiver of a device is terminated if the particular telemetry system remains dormant or inactive for a programmable period of time and power to the transceiver is turned on if a particular signal is received by the implantable device.

Abstract: Leads having directional electrodes thereon. Also provided are leads having directional electrodes as well as anchoring prongs to secure the electrodes to the leads. Also provided are leads with directional electrodes where all the electrodes have the same surface area. Methods of treating conditions and selectively stimulating regions of the brain such as the thalamus and cerebellum are also provided.

Abstract: A lead stimulation/recording system is provided, which is a combination of a permanent DBS stimulating lead and a recording microelectrode. The DBS lead has a lumen extending from the proximal to the distal end of the lead, the lumen having an opening on each end of the lead. The microelectrode is configured and dimensioned to be insertable into the DBS lead from either the distal or proximal opening of the DBS lead, thereby permitting the microelectrode to be placed before, concurrently with, or after placement of the DBS lead. In addition, the system may be used with known microelectrode recording systems and methods of inserting the electrodes, such as the five-at-a-time method, the dual-microdrive method, or the single microdrive method.

Abstract: An implantable medical device and associated method perform ECG morphology monitoring. A subcutaneous ECG signal and a posture signal are sensed in a patient. A cardiac condition is detected in response to the ECG signal and the posture signal. In one embodiment, multiple ECG morphology templates corresponding to each of a number of different patient postures are acquired and stored for use in detecting a cardiac condition.

Abstract: A lead for deep electrical neurostimulation comprising a rod of biocompatible material and a blade, also of biocompatible material, secured to one end of the rod and in alignment therewith. The blade presents two main faces and a plurality of electrodes disposed on at least one of the two main faces in a two-dimensional configuration. The electrodes are connected to conductor elements disposed inside or on a surface of said rod. A deep electrical neurostimulation system comprising an electrical pulse generator connected to at least one lead of the above-described type is also disclosed.

Abstract: A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.

Abstract: An electromagnetic device and method of operation thereof are disclosed. The electromagnetic device contains an electromagnetic field generator, a microcurrent generator and a photonic accumulator. The electromagnetic field generator generates broadband electromagnetic fields to substantially envelope a subject placed in proximity thereto. The subject is placed in contact with microcurrent electrodes so as to permit a broadband microcurrent to flow through the subject or along the surface of the subject. A photonic accumulator is positioned proximate the subject to receive biophotons emitted therefrom and to activate the biophotons with a light source.

Abstract: In an implantable biventricular heart stimulating device, and a biventricular heart stimulating method, wherein operation takes place normally with a time VV between a pacing pulse delivered, or inhibited, by a first ventricular pacing circuit and a pacing pulse delivered, or inhibited, by a second ventricular pacing circuit, and wherein a time VVcts is determined that is to be used instead of VV during a capture threshold search.

Abstract: Techniques for performing a lead integrity test during a suspected tachyarrhythmia are described. An implantable medical device (IMD) may perform the test prior to delivering a therapeutic shock to treat the suspected tachyarrhythmia and, in some cases, may withhold the shock based on the test. In some examples, the IMD measures an impedance of a lead a plurality of times during the suspected tachyarrhythmia. In some examples, the IMD measures the impedance a plurality of times between two sensed events of the suspected tachyarrhythmia. The IMD or another device may determine a variability of, or otherwise compare, the measured impedances to evaluate the integrity of the lead. Instead of or in addition to withholding a shock, the IMD or another device may change a sensing or stimulation vector of the IMD, or provide an alert to a user, if the integrity test indicates a possible lead integrity issue.

Abstract: A medical system with a medical device and with a supply unit. The supply unit is designed to be separably connected to the medical device and to supply the medical device with electric energy without interruption. The medical system has an isolating transformer and a changeover device, wherein the changeover device is connected to the isolating transformer and to the medical device and is designed to connect the medical device or the supply unit to an electric supply network via the isolating transformer as desired.

Abstract: A method of promoting the healing of a lesion in a smooth muscle (200), comprises selecting a smooth muscle portion having a lesion, and applying a non-excitory electric field (210) to the portion, which reduces the mechanical activity of the portion.

Abstract: Tissue ablation probes and methods for treating tissue are provided. The tissue ablation probe comprises an elongated probe shaft, at least one electrode carried by the distal end of the probe shaft, and a pharmaceutical agent carried by the probe shaft. The pharmaceutical agent may be disposed on the electrode(s), the probe shaft, or a releasable portion associated with the electrode or the probe shaft. A method for treating tissue comprises introducing a tissue ablation probe to a tissue site, operating the tissue ablation probe to ablate tissue at the tissue site, and releasing a pharmaceutical agent from the tissue ablation probe at the tissue site.

Abstract: A method includes inserting a target probe along a first path within a body such that a portion of the target probe is disposed adjacent a target location within the body. The target location can be, for example, a portion of a nerve, a muscle or the like. An electronic implant is inserted along a second path within the body such that a portion of the electronic implant is disposed adjacent the target location within the body. The second path is different from the first path. The electronic implant is inserted when the target probe is disposed adjacent the target location within the body.

Abstract: The implantable, electrically operated medical device system comprises an implanted radio frequency (RF) receiving unit (receiver) incorporating a back-up rechargeable power supply and an implanted, electrically operated device, and an external RF transmitting unit (transmitter). RF energy is transmitted by the transmitter and is coupled into the receiver which is used to power the implanted medical device and/or recharge the back-up power supply. The back-up power supply within the receiver has enough capacity to be able to, by itself, power the implanted device coupled to the receiver for at least 24 hours during continual delivery of medical therapy. The receiver is surgically implanted within the patient and the transmitter is worn externally by the patient. The transmitter can be powered by either a rechargeable or non-rechargeable battery. In a first mode of operation, the transmitter will supply power, via RF coupled energy, to operate the receiver and simultaneously recharge the back-up power supply.