Abstract: The invention provides an apparatus for cutting an endocardial lead within a patient. The apparatus includes a tubular member and a tension member disposed therein. The tension member includes a distal end and a proximal end. A blade is affixed to the distal end of the tension member and an adjustment mechanism is adapted to adjust the tension member and blade between an extended position and a retracted position. The adjustment mechanism includes a female member, a male member and an anchor. The anchor is affixed to the proximal end of the tension member and the male member. Insertion and withdrawal of the male member within the female member moves the tension member and the blade between the extended position and the retracted position. An alternate embodiment includes a capture mechanism or guide wire for drawing the apparatus and lead closer together before extending the blade and cutting the lead.

Abstract: An aspect relates to a system for providing baroreflex stimulation. An embodiment of the system comprises a heart rate monitor to sense a heart rate and provide a signal indicative of the heart rate, and a baroreflex stimulator. The stimulator includes a pulse generator to intermittently generate a stimulation signal to provide baroreflex stimulation for a baroreflex therapy, and further includes a modulator to adjust the stimulation signal based on the signal indicative of the heart rate such that the stimulation signal provides a desired baroreflex stimulation corresponding to a desired heart rate.

Abstract: A method and system for selective inhibition of somatic nerve fibers in a mixed nerve containing both somatic and autonomic nerve fibers where the method finds use in treatment of chronic pain, spastic muscles and for sensory and motor control of a bladder. The methods and systems utilize alternate phase rectangular electrical pulses. An electrical pulse generator is coupled to a nerve. An alternate phase high frequency, low amplitude pulse is first applied to selectively inhibit somatic nerves when present in a mixed nerve. An alternate phase low frequency, high amplitude phase pulse subsequently supplied to stimulate the autonomic nerve fibers and in the case of the sacral root will permit a controlled voiding of the bladder and bowel.

Abstract: A system and apparatus for enabling independent, highly reliable and accurate self-application of an anti-tremor means by a disabled patient, without requirement for application fixtures, wherein anti-tremor means comprises a single unit, self adhesive stimulation and recording electrode with an integrated supply of energy and a control unit, further comprising an alignment, and application means for applying said anti-tremor means configured to enable independently self application by a severely handicapped patient, wherein system and method for tremor reduction is by means of closed-loop functional electrical stimulation, including a sensor for sensing muscle movements, and Functional Electrical Stimulation (FES) apparatus for providing FES to a muscle, the FES apparatus being in communication with the sensor via a band pass filter for filtering around a tremor frequency to ignore slow movements and high frequency noise.

Abstract: Systems and methods include sensing whether a shock to a heart is needed, and prior to delivering the shock, causing at least a partial contraction of a musculature in a chest, and delivering the shock while the musculature is at least partially contracted to reduce the pain of shock therapy.

Abstract: The catheter is guided along a blood vessel of a patient by the bipolar electrode functioning as a mobile sensor on the catheter tip connected to the electronic unit to monitor the advance of the catheter and determine any modification of successive signals received from the bipolar electrode in order to detect any deviation of the catheter tip from the required path along the blood vessel and to deliver control signals comprising a GO signal, a STOP signal or an END signal to respectively enable, interrupt or terminate the advance of the catheter. The bipolar electrode moreover serves to verify the contact of the catheter tip with the wall of the heart cavity of the patient by creating impulses and detecting the appearance of corresponding induced signals on a surface cardiogram of the patient. The combination of the bipolar electrode on the catheter with the electronic unit provides a portable catheterization system particularly suitable for performing urgent cardiac catheterizations outside hospitals.

Abstract: A catheter with a tissue property sensor provides for localization of myocardial infarction (MI) by utilizing one or more differences between properties of infarcted myocardial tissue and properties of normal myocardial tissue. The tissue property sensor is to be placed on endocardial wall or epicardial wall during catheterization to sense at least one tissue property allowing for detection of MI. Examples of the tissue property sensor include, but are not limited to, an optical sensor, an acoustic sensor, a contractility sensor, a temperature sensor, and a drug response sensor. In one embodiment, the tissue property sensor senses a tissue property in various locations on endocardial wall or epicardial wall and detects substantial changes in the tissue property that indicate a boundary between infarcted tissue and normal tissue.

Abstract: Compact electronic modules, which may be used with implantable microstimulators and other medical and non-medical devices, and manufacture/assembly of such modules are described. Component and circuitry designs utilize unique redistribution techniques and attachment methods. A number of component designs and packaging configurations maximize the volume efficiency of electronic modules. Also included are improved processes and systems enabling the manufacture and assembly of such compact packages.

Abstract: Methods and an apparatus are described for treating at least one of a plurality of disorders of a patient characterized at least in part by vagal activity innervating at least one of a plurality of organs of the patient. Embodiments include a method for treating a patient having a gastro-intestinal disorder having a inflammatory basis, including positioning an electrode on a vagus nerve below a vagal innervation of a heart of the patient, and treating the patient's gastro-intestinal disorder by applying an electrical signal to the electrode, wherein the signal has a frequency of at least 500 Hz and is selected to down-regulate neural activity on the vagus nerve, allow partial restoration of nerve activity upon discontinuation of the electrical signal, and wherein the signal is configured to reduce pancreatic output and biliary output. An electrical signal is applied to the electrode to modulate vagal activity by an amount selected to treat the disorder. The signal may be blocking or a stimulation signal.

Abstract: A method of tuning a cardiac prosthetic pacing device includes (a) monitoring the flow output from the heart, and (b) adjusting the timing of pacing events by the cardiac prosthetic pacing device so as to optimise the flow from the heart under operational conditions.

Abstract: A power supply for an implantable cardioverter-defibrillator for subcutaneous positioning between the third rib and the twelfth rib and using a lead system that does not directly contact a patient's heart or reside in the intrathoracic blood vessels and for providing anti-bradycardia pacing energy to the heart, comprising a capacitor subsystem for storing the anti-bradycardia pacing energy for delivery to the patient's heart; and a battery subsystem electrically coupled to the capacitor subsystem for providing the anti-bradycardia pacing energy to the capacitor subsystem.

Abstract: Systems and methods selectively stimulate components of the pudendal nerve away from the sacral root to evoke desired physiologic responses in persons who lack the ability to otherwise produce these responses—e.g., maintain continence and/or produce micturition, and/or provide male/female sexuality responses, and/or provide bowel responses. The systems and methods use a multiple electrode array, or individual electrodes, placed on, in, or near the pudendal nerve. The electrode array, or individual electrodes, in association with a pulse generator, provide selective stimulation of individual fascicles within the pudendal nerve, to achieve different physiologic responses.

Abstract: A medical electrical lead for spinal cord stimulation includes a first column of electrode surfaces and a second column of electrode surfaces, both coupled to a distal portion of the lead such that the two columns extend alongside one another and are spaced apart from one another. Each electrode surface of the first column is coupled to a corresponding conductor of a first plurality of conductors of a first lead body, and each electrode surface of the second column is coupled to a corresponding conductor of a second plurality of conductors of a second lead body. The first and second lead bodies are coupled together by the distal portion of the lead, and each electrode surface extends laterally away from the respective lead body.

Abstract: Systems, Methods, and Computer Program Products for Transmitting Neural Signal Information. Systems, method, and computer program products are provided for neural signal transmission. A system according to one embodiment can include a signal receiver operable to receive a neural signal comprising an action potential. The system can also include an action potential detector operable to communicate with the signal receiver and detect when the action potential occurs. In addition, the system can include a transmitter in communication with the action potential detector and operable to transmit an information signal indicating the time when the action potential occurs and, in addition, can transmit samples associated with a detected action potential.

Abstract: An implantable medical device with a main processor also has a telemetry processor to perform some telemetry processing functions resulting under some circumstances in reducing demands on the main processor, conserving energy, increasing telemetry processing speed, and many other advantages. A wide variety of implantable medical devices can be configured with a telemetry processor including neuro stimulators, pacemakers, defibrillators, drug delivery pumps, diagnostic recorders, and cochlear implants. The telemetry processor includes control logic, a data decoder, a receive buffer, a data encoder, and a transmit buffer. Methods of receiving messages and transmitting messages with a telemetry processor are also disclosed.

Abstract: A heartwire comprises a wire having a proximal end and a distal end, at least part of the distal end being conductive so as to be usable in heart stimulation; and attached to said distal end, an end structure adapted for non-invasively maintaining the distal end in position adjacent the heart. The end structure may comprise an irregular or three-dimensional, atraumatic structure adapted for engaging a surgical material secured to the heart, for maintaining said heartwire in position relative to said surgical material. The surgical material may be a pledget, and the end structure may comprise at least one of a pigtail, a hook, a tine and a suture sized and shaped for engaging the pledget so as to maintain the heartwire in position. The heartwire may comprise a second wire having a corresponding distal end structure and may be a bipolar heartwire. An arrangement for stimulating a heart may comprise the foregoing heartwire, in combination with a surgical material for being secured to the heart.

Abstract: A system and method for classifying cardiac depolarization complexes in which waveforms of a depolarization complex are sensed by separate electrodes and correlated with template waveforms of a template depolarization complex. The system is particularly suitable for incorporation into a cardiac rhythm management device such as an implantable cardioverter/defibrillator or pacemaker in order to facilitate arrhythmia prediction and/or prevention.

Abstract: A combination of a defibrillator and an electrode package, the combination comprising a defibrillator comprising electrical output wires for delivering a defibrillation pulse to defibrillation electrodes, processing circuitry and associated software for controlling the delivery of the defibrillation pulse, an electrical energy storage element for storing the energy delivered in the defibrillation pulse, a user interface element or elements connected to the processing circuitry for accepting one or more inputs from the user and communicating one or more pieces of information to the user, a housing containing the storage element, processing circuitry, and user interface, and a first mechanical element or elements on the exterior of the housing and configured so that an electrode package can be mechanically attached to the exterior of the housing substantially in full view on the exterior, and an electrode package containing the defibrillation electrodes, the package comprising an outer shell, a portion of the o

Abstract: A system for treating neurological conditions by low-frequency time varying electrical stimulation includes an electrical device for applying such low-frequency energy, in a range below approximately 10 Hz, to the patient's brain tissue. An implantable embodiment applies direct electrical stimulation to electrodes implanted in or on the patient's brain, while a non-invasive embodiment causes a magnetic field to induce electrical currents in the patient's brain.

Abstract: A method and apparatus include a therapeutic or developmental instrument that includes hardware and/or software for stimulating a muscle. Such an instrument may comprise, for instance, a golf club, a baseball bat, a lacrosse stick, a tennis racquet or a hockey stick, among other sports-related instruments. Still other suitable instruments may include a writing instrument, such as a pen. In the case of a golf club, a muscle of a user may be stimulated by the instrument as the golfer practices her swing. Combining such muscle stimulation with the act of practicing the movement of the swing has a synergistic effect of training the muscle as it builds strength. Similarly, a partial paralytic may regain strength in their hand by holding and writing with a pen configured to transcutaneously deliver a stimulating signal. Where desired, the instrument may include at least one electrode configured to deliver a stimulating signal to the holder of the instrument.