Abstract: Embodiments of the present disclosure, in one aspect, relate to compositions including a silver/silica nanocomposite, methods of making a silver/silica nanocomposite, methods of using a silver/silica nanocomposite, and the like.
Type:
Grant
Filed:
October 31, 2012
Date of Patent:
November 15, 2016
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A method of purifying a Luo Han Guo extract includes contacting the Luo Han Guo extract with activated carbon and a macroporous polymeric adsorbent resin, an ion exchange resin, or both.
Type:
Grant
Filed:
March 17, 2014
Date of Patent:
October 25, 2016
Assignee:
Tate & Lyle Ingredients Americas LLC
Inventors:
Brian Timothy Pohrte, Timothy C. Schunk, Elber F. Tejada
Abstract: A composition for the treatment of acne includes hydrolyzed psoralea corylifolia, containing a component bakuchiol, is solubilized in a water-based solution. The composition is for topical application to the skin. In various implementations, the composition is a water-based acne gel or a water-based cleanser. In a specific implementation, a composition includes Bakutrol™, which includes bakuchiol, and bisabolol. The composition can include a polysorbate surfactant. In implementations, these ingredients are combined with other active ingredients, including for example, salicylic acid, benzoyl peroxide, tretinoin, retinol, tazarotene, or an antibiotic, or a combination of these. A process of preparation of the composition allows for the stabilization of Bakutrol in solution.
Type:
Grant
Filed:
April 21, 2015
Date of Patent:
September 6, 2016
Assignee:
Envy Medical, Inc.
Inventors:
Felipe Jimenez, Lyndon Garcines, Susan Goldsberry, Senad Ibrulj
Abstract: A non-ionic surfactant aggregate comprises a water insoluble biocidally active ingredient, a non-ionic surfactant system, and water. The non-ionic surfactant system comprises first and second non-ionic surfactants.
Type:
Grant
Filed:
October 7, 2005
Date of Patent:
September 6, 2016
Assignee:
ENVIROQUEST RESEARCH LIMITED
Inventors:
Howard Bernard Dawson, Martin Balderstone
Abstract: The present invention relates to solubility improving preparation for enhancing the oral absorption of a poorly soluble drug, which is comprising (A) and (B); (A) a granulated substance which comprises (i) a poorly soluble drug having an acidic group in the molecule, (ii) an alkaline agent, (iii) a surfactant, and this granulated substance dose not substantially contain a disintegrator, (B) a disintegrator existing only in the external of the granulated substance.
Abstract: The present invention relates to a carrier system for fragrances, to the production thereof and to the use of the carrier system in laundry and cosmetic formulations. Accordingly, the present invention is directed to a microcapsule comprising a core of hydrophobic material composed of at least one fragrance or perfume and a microcapsule shell obtainable by the suspension polymerization of the following monomers: (a) one or more C1-C24-alkyl ester(s) of (meth)acrylic acid (monomer A), (b) one or more bi- or polyfunctional monomers (monomer B) and (c) optionally, one or more other ethylenically unsaturated monomers (monomer C), wherein the shear rate for the preparation of the emulsion lies in the range of from 150 to 500 rpm and the stirring time for the preparation of the emulsion lies in the range of from 15 min to 180 min.
Type:
Grant
Filed:
August 27, 2013
Date of Patent:
August 23, 2016
Assignee:
GIVAUDAN S.A.
Inventors:
Matthias Laubender, Ouidad Benlahmar, Regina Klein, Joseph Stracke, Patrick Leibach, Jeremy Ness
Abstract: Described herein are compositions comprising an acidifier intermixed with an emulsifier and a co-surfactant that form stable microemulsions in water. Also described are methods of dispersing a compound in an aqueous solution using the compositions of the present invention.
Abstract: The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and a partner drug, processes for the preparation thereof, and their use to treat certain diseases.
Type:
Grant
Filed:
August 27, 2015
Date of Patent:
August 16, 2016
Assignee:
Boehringer Ingelheim International GmbH
Inventors:
Thomas Friedl, Michael Braun, Kenji Egusa, Hikaru Fujita, Megumi Maruyama, Takaaki Nishioka
Abstract: Sheet for cutaneous application comprising a support layer made of loosely woven fabric embedded in a layer of silicone elastomer incorporating vitamin E or an ester thereof, wherein the layer of silicone elastomer has a thickness less than or equal to 2.0 mm and the silicone elastomer contains an elasticity modifier consisting of a triglyceride of saturated C8-C18 fatty acids.
Abstract: A cosmetic product includes a water-in-oil emulsion containing: a) at least one cosmetic active ingredient, b) at least one water-in-oil emulsifier, c) at least one non-ionic polyalkylene glycol ether having a HLB value >7, d) at least one C8-C16 isoparaffin, and also including at least one propellant and an aerosol dispensing device. The emulsion has a high stability, a reduced susceptibility to corrosion, a good cosmetic effect and reduced formation of deposits during the application thereof.
Abstract: The present invention relates to prasugrel or a pharmaceutically compatible salt thereof, compositions that contain this active substance and pharmaceutical compositions that contain this active substance or a composition containing this active substance. The present invention further relates to methods for producing the novel compositions.
Abstract: Methods of normalizing iron levels, treating iron deficiency and disorders related thereto, such as anemia, as described. Pharmaceutical compositions effective for such treatments are also described.
Type:
Grant
Filed:
June 9, 2011
Date of Patent:
August 2, 2016
Assignee:
EMISPHERE TECHNOLOGIES, INC.
Inventors:
Gary M. Riley, Parshuram Rath, Michael Novinski
Abstract: A bone replacement filler comprising a biomedical ceramic particulate, wherein the filler is able to flow without the application of an external shear stress or compressive force or under a relatively low shear stress or compressive force, but resists flow or does not flow when subjected to a higher shear stress or compressive force, and wherein at least some of the particles in the ceramic particulate have a micro-porous surface structure and/or a micro-porous sub-surface structure.
Abstract: The present invention provides methods and compositions for treating hepatocellular carcinoma (HCC) by administering a composition comprising nanoparticles that comprise a taxane and an albumin. The invention also provides combination therapy methods of treating HCC comprising administering to an individual an effective amount of a composition comprising nanoparticles that comprise a taxane and an albumin and another agent, such as an agent that inhibits microtubule disassembly.
Abstract: The compositions and methods of this invention relate to skin care compositions containing: (a) hydrophobic and hydrophilic, linear cellulose particles having an average length of from about 1 to about 1000 ?m, a particle aspect ratio from about 1000 to about 2 and a thickness of from about 1 to about 500 ?m; (b) amphiphilic linear cellulose particles derived from sources selected from the following group: citrus pulp, sugar beet pulp, banana pulp, mango pulp, apple pulp, passion fruit pulp and tomato pulp and the like, said particles having an average size of from about 1 to about 1000 ?m, a particle aspect ratio from about 1000 to about 2 and a thickness of from about 1 to about 500 ?m; wherein the ratio of ingredient (b) to ingredient (a) is from about 1:10 to about 10:1; and a cosmetically acceptable carrier.
Type:
Grant
Filed:
October 23, 2013
Date of Patent:
June 21, 2016
Assignee:
Johnson & Johnson Consumer Inc.
Inventors:
Patricia Bonner, Claudia Kaminski, Danielle Lima Lorenzetti, Prithwiraj Maitra, Juliana Salles Moscardi, Jeffrey M. Wu
Abstract: The compositions and methods of this invention relate to a leave-on skin care composition containing hydrophobic, linear cellulose particles having an average length of from about 1 to about 500 ?m, a particle aspect ratio from about 2 to about 25 and an average thickness of from about 1 to about 500 ?m; and a cosmetically acceptable carrier.
Type:
Grant
Filed:
April 23, 2014
Date of Patent:
June 14, 2016
Assignee:
Johnson & Johnson Consumer Inc.
Inventors:
Patricia Bonner, Claudia Kaminski, Danielle Lima Lorenzetti, Prithwiraj Maitra, Juliana Salles Moscardi, Jeffrey M. Wu
Abstract: This invention relates to compositions and methods useful in treating dermatological disorders. In particular, the methods include applying a composition that includes a reactive reinforcing component; and a cross-linking component; in which the cross-linking component facilitates in situ cross-linking of the reactive reinforcing component, such that a film is formed on skin, thereby treating the dermatological disorder.
Type:
Grant
Filed:
September 21, 2012
Date of Patent:
May 10, 2016
Assignee:
OLIVO LABORATORIES, LLC
Inventors:
Betty Yu, Joseph Lomakin, Soo-Young Kang, Benjamin W. Adams
Abstract: The invention relates to the use of stable atomic quantum clusters (AQC) with antimicrobial activity. The stable AQCs include at least 500 metal atoms (Mn, n<500), the metals being selected from among Au, Ag, Co, Cu, Pt, Fe, Cr, Pd, Ni, Rh, Pb or bi- or multi-metallic combinations thereof. Said AQCs are used as antimicrobial agents, antifungal agents and biocides at concentrations of the order of between 1 nM and 100 nM or more in relation to atoms of the corresponding metal. The antimicrobial activity is specific to both the type of metal and size of cluster used.
Type:
Grant
Filed:
October 1, 2008
Date of Patent:
April 19, 2016
Assignee:
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
Inventors:
Manuel Arturo Lopez Quintela, José Rivas Rey, María Carmen Blanco Varela
Abstract: A composition for the treatment of acne includes hydrolyzed Psoralea Corylifolia, containing a component bakuchiol, is solubilized in a water-based solution. The composition is for topical application to the skin. In a specific implementation, the composition is a water-based acne gel. In a specific implementation, a composition includes Bakutrol™, which includes bakuchiol, and bisabolol. The composition can include a polysorbate surfactant. In implementations, these ingredients are combined with other active ingredients, including for example, salicylic acid. A process of preparation of the composition allows for the stabilization of Bakutrol in solution.
Type:
Grant
Filed:
March 1, 2013
Date of Patent:
March 29, 2016
Assignee:
Envy Medical, Inc.
Inventors:
Lyndon Garcines, Susan Goldsberry, Senad Ibrulj