Patents Examined by L. Martinez
  • Acceleration of growth
    Patent number: 10633630
    Abstract: The invention is in the field of growth of Mycobacteria. In particular, agents have been identified which enhance the growth of Mycobacterial species, which are naturally slow-growing. Such agents can therefore be used in the identification of Mycobacteria and in the diagnosis of Mycobacterial infections.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: April 28, 2020
    Assignee: ST GEORGE'S HOSPITAL MEDICAL SCHOOL
    Inventors: Timothy John Bull, Kai Hilpert
  • Methods and compositions for improved cognition
    Patent number: 10632180
    Abstract: Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: April 28, 2020
    Assignee: The Regents of the University of California
    Inventor: Dena Dubal
  • Exercise-regulated adipokines as therapy for diabetes management
    Patent number: 10632175
    Abstract: The present invention is related to methods and compositions effective in regulating glycemic control in subject individuals in need of the regulation of glycemic control. Said individuals may have diabetes or be prediabetic condition receive therapeutically effective amounts of identified secreted proteins in an amount suitable for modulating glycemic control and to thereby treat or prevent diabetes in said subject.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: April 28, 2020
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Laurie J. Goodyear, Kristin I. Stanford
  • Fluorescent marker for tissue staining containing phosphor-containing nanoparticle and method using same
    Patent number: 10627325
    Abstract: A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: April 21, 2020
    Assignee: KONICA MINOLTA, INC.
    Inventors: Takuji Aimiya, Hideki Gouda, Hisatake Okada, Yasushi Nakano
  • Bactericidal peptides and uses thereof
    Patent number: 10624947
    Abstract: Antimicrobial compositions having bactericidal activity are described. Also described is a method of treating bacterial infections using compositions comprising antimicrobial peptides or variants thereof.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: April 21, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: C. Cheng Kao, Dean Rowe-Magnus, Antonio Cembellin Prieto
  • Peptide derivatives and uses thereof
    Patent number: 10626144
    Abstract: The invention provides for novel peptide derivatives and compositions comprising the same. The invention further provides methods of treatment comprising administering novel peptide derivatives and/or compositions comprising the same.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: April 21, 2020
    Assignee: Nosopharm
    Inventors: Philippe Villain-Guillot, Maxime Gualtieri, Emilie Racine
  • Assays for detecting analytes in samples and kits and compositions related thereto
    Patent number: 10620196
    Abstract: The present invention provides methods of detecting analytes using particles having different physico-chemical properties, such as buoyancy, size, density, spectral characteristics, and/or binding properties, in solution-based sandwich assays and solution-based competition assays. The methods can be performed using rotors and bench-top centrifuges and provide for rapid, qualitative and quantitative detection of analytes. The present invention also provides kits that can be used to perform the methods, and mixtures containing particles suitable for the methods.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: April 14, 2020
    Assignee: ABAXIS, INC.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron
  • Device for performing a diagnostic test and methods for use thereof
    Patent number: 10613082
    Abstract: Assay cassettes and testing devices that can be used to provide rapid, accurate, affordable, laboratory-quality testing at the point of care. Such assay cassettes and testing devices are designed to provide rapid, quantitative test results in a point-of-care setting or the like. Likewise, such assay cassettes and testing devices may eliminate or replace expensive, centralized clinical testing equipment and technical personnel. Such testing device may include automated data reporting and decision support. Methods for performing point of care diagnostic tests are also disclosed.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: April 7, 2020
    Assignee: i-calQ, LLC
    Inventor: Joel R. L. Ehrenkranz
  • Device, system, and method including micro-patterned cell treatment array
    Patent number: 10610635
    Abstract: Devices, systems, or methods are disclosed herein for treatment of disease in a vertebrate subject. The device can include a quasi-planar substrate; and one or more laterally-mobile effector molecule types at least partially embedded within the quasi-planar substrate, wherein the one or more laterally-mobile effector molecule types is configured to interact with one or more cell types. The device can further include one or more sensors configured to detect at least one aspect of an interaction between the at least one of the one or more laterally-mobile effector molecule types and the one or more cell types; and a controller in communication with the one or more sensors, wherein the controller is configured to responsively initiate modification of at least one of the one or more laterally-mobile effector molecule types, the quasi-planar substrate, and the one or more cell types.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: April 7, 2020
    Assignee: Gearbox LLC
    Inventors: Roderick A. Hyde, Lowell L. Wood, Jr.
  • Electrochemical immunosensor and method of use for analyte detection
    Patent number: 10605806
    Abstract: A carbon nanofiber-based label free electrochemical immunosensor for sensitive detection of proteins in a fluid is described. The immunosensor as disclosed is a modified carbon nano-fiber screen printed electrode (CNF-SPE) wherein the electrode is modified with a carboxyphenyl film and then activated by EDC/NHS. Further, a monolayer of 4-aminophenylboronic acid coating was then fabricated onto the electrode to allow orientation of antibody via bonding of boronic acid-saccharide of oligosaccharide moiety located on the Fc region of antibody. The modified electrode is then used for the detection of a hormone such as rbST in a fluid with a detection limit of 1 pg/ml.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: March 31, 2020
    Assignee: Universiti Brunei Darussalam
    Inventors: Syazana Abdullah Lim, Minhaz Uddin Ahmed
  • H-field imager for assays
    Patent number: 10605816
    Abstract: This disclosure describes a magnetic-field image sensor and method of use. In accordance with implementations of the magnetic-field image sensor, a sample can be placed on top of the magnetic field image sensor. An image of the magnetic nanoparticles or superparamagnetic nanoparticles can be created immediately afterwards based upon detection of a change in magnetic field caused by the magnetic nanoparticles or superparamagnetic nanoparticles. From this image, computer imaging algorithms can determine attributes (e.g., size, shape, type, quantity, distribution, etc.) of the target entity.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: March 31, 2020
    Assignee: MAXIM INTEGRATED PRODUCTS, INC.
    Inventors: Ronald B. Koo, Henry Grage
  • Skin whitening peptide agents
    Patent number: 10603265
    Abstract: The present invention provides new peptides useful as skin whitening agents and their uses in cosmetic or therapeutic applications.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: March 31, 2020
    Assignees: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Graca Raposo, Cecile Campagne, Cedric Delevoye
  • Lateral flow blotting assay
    Patent number: 10598659
    Abstract: A lateral flow apparatus is provided.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: March 24, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Clayton T. McKee, William Strong, Mingde Zhu, Emmanuel Quiroz
  • Bracelet
    Patent number: D879647
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: March 31, 2020
    Assignee: Van Cleef & Arpels SA
    Inventor: Isabelle Parvex
  • Gemstone
    Patent number: D879652
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: March 31, 2020
    Assignee: BONOLI S.R.L.
    Inventor: Massimiliano Bonoli
  • Jewelry article
    Patent number: D881737
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: April 21, 2020
    Assignee: Tuff-Links, LLC
    Inventor: Keith E. Matheny
  • Gemstone
    Patent number: D881744
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: April 21, 2020
    Assignee: BONOLI S.R.L.
    Inventor: Massimiliano Bonoli
  • Wrap
    Patent number: D882125
    Type: Grant
    Filed: January 15, 2018
    Date of Patent: April 21, 2020
    Inventors: Bruno Divito, Manuele Scarati
  • Landscape edging
    Patent number: D882126
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: April 21, 2020
    Assignee: Dimex, LLC
    Inventors: Patrick Amrine, Andy Antil, Lyle A. James, Emily C. Martin, Matthew T. Miller, Kevin R. Morey
  • Band
    Patent number: D882446
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: April 28, 2020
    Assignee: EQUALITUDE, INC.
    Inventors: Imelda Atkinson, Douglas Kaplan