Patents Examined by L. Morris
  • Process for the manufacture of 6-alkynyl-pyridine derivatives
    Patent number: 11053237
    Abstract: The application includes a description of novel intermediates, of new manufacturing steps resulting in a novel and improved process for producing the intermediates and the final compounds, i.e., 6-alkynyl-pyridine derivatives. The intermediates of the invention are useful to produce 6-alkynyl-pyridine derivatives, which compounds are useful for the treatment of cancer.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: July 6, 2021
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Guanghua Lu, Guenther Huchler, Thomas Krueger, Michael Pangerl, Marco Santagostino, Jean-Nicolas Desrosiers
  • Power-supplying device and assembly method of power-supplying device
    Patent number: 11046260
    Abstract: There is provided a power-supplying device and an assembly method thereof. By causing a first-turning member, which locks with an one end of a coil spring by a first-locking section, and a first support, which locks with the other end thereof by a second-locking section, to rotate relative to each other in the direction that is opposite to the biasing direction, and causing an engaging part and an engaged part to be in an engaged state by engaging with each other, thereby, maintaining the state where the initial biasing force is being imparted to the first turning member, is enabled, and the first support and a second support member are easily assembled to each other to make a turning member be supported, and thus, assembly properties can be made enhanced.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: June 29, 2021
    Assignee: Yazaki Corporation
    Inventors: Tsukasa Sekino, Hiroshi Yamashita, Daisuke Okamoto
  • Tipping prevention unit, feeding apparatus, and image forming apparatus
    Patent number: 11046345
    Abstract: A tipping prevention unit that prevents tipping of an image forming apparatus includes shafts holding a wheel of the image forming apparatus, a shaft that abuts the image forming apparatus at a position higher than the shafts, and a shaft that contacts a floor surface on which the image forming apparatus is placed at a position further protruding to the outside of the image forming apparatus than the wheel of the image forming apparatus.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: June 29, 2021
    Assignee: Canon Kabushiki Kaisha
    Inventors: Takaaki Kawade, Tomoki Katafuchi
  • (S)-N-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-yl)-1-(2-(4-(4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)-3,6-dihydropyridin-1(2H)-yl)-2-oxoethyl)-3-(methylthio)pyrrolidine-3-carboxamide compositions for pharmaceutical preparations
    Patent number: 11034673
    Abstract: A composition comprising (S)—N-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-yl)-1-(2-(4-(4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)-3,6-dihydropyridin-1(2H)-yl)-2-oxoethyl)-3-(methylthio)pyrrolidine-3-carboxamide and hypromellose acetate succinate for pharmaceutical preparations, especially capsule preparations.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: June 15, 2021
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Pranav Gupta, Jiansheng Wan
  • Aminopyridine derivatives as TAM family kinase inhibitors
    Patent number: 11034686
    Abstract: Provided herein are aminopyridine derivatives and pharmaceutical compositions that are useful as TAM family kinase inhibitors.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: June 15, 2021
    Assignee: SignalChem Lifesciences Corporation
    Inventor: Zaihui Zhang
  • Aminopyridine derivatives as TAM family kinase inhibitors
    Patent number: 11034685
    Abstract: Provided herein are aminopyridine derivatives and pharmaceutical compositions that are useful as TAM family kinase inhibitors.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: June 15, 2021
    Assignee: SignalChem Lifesciences Corporation
    Inventor: Zaihui Zhang
  • Salt of substituted piperidine compound
    Patent number: 11028069
    Abstract: An object of the present invention is to provide a salt of the compound 1-(2,3-dichlorobenzoyl)-4-((5-fluoro-6-(5-methyl-1H-pyrazol-3-ylamino)pyridin-2-yl)methyl)piperidine-4-carboxylic acid, useful as an antitumor agent, and crystals thereof which are excellent in solubility, stability, and oral absorption and can be produced in large quantities. The present invention relates to a hydrochloride salt of 1-(2,3-dichlorobenzoyl)-4-((5-fluoro-6-(5-methyl-1H-pyrazol-3-ylamino)pyridin-2-yl)methyl)piperidine-4-carboxylic acid and crystals of the hydrochloride salt having characteristic peaks at particular diffraction angles in powder X-ray diffraction spectrum.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: June 8, 2021
    Assignee: TAIHO PHARMACEUTICAL CO., LTD.
    Inventor: Morihiro Mitsuya
  • Compounds for the treatment of paramyxovirus viral infections
    Patent number: 11014935
    Abstract: Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: May 25, 2021
    Assignee: Janssen BioPharma, Inc.
    Inventors: Guangyi Wang, Leonid Beigelman, Anh Truong, Carmela Napolitano, Daniele Andreotti, Haiying He
  • Forms of (R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4- yl)cyclohexyl)propanamide
    Patent number: 11014890
    Abstract: Forms B and C of (R)—N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide are stable under the conditions of light, high temperature and high humidity.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: May 25, 2021
    Assignee: SHENZHEN RENTAI PHARMATECH LTD
    Inventors: Dongxu Yi, Guobin Ren, Jian Ma, Shuhao Wen, Peiyu Zhang, Yang Liu, Xuekun Shi, Jiajun Huang, Yanqi Zhang, Shigang Ruan, Mingjun Yang, Guangxu Sun
  • Folding stand for electronic device
    Patent number: 11013317
    Abstract: A folding stand is provided with a rectangular base (1) including two parallel sets of top slots (11), two bottom cavities (12), and aside hole (15); a rectangular panel (2) hingedly secured to a front end of a top of the base (1) and including two sets of two parallel grooves (21), two spacers (22) moveably disposed in the grooves (21) of different sets or in the side hole (15), and a front, pivotal ledge (23); a support arm (3) having two ends pivotably secured to a bottom of the panel (2) and selectively disposed in the slots (11) of different sets; two aligned extension arms (4) each having one end pivotably secured to one of two rear corners of the base (1), the extension arm (4) including a lengthwise trough (41); and two legs (5) pivotably disposed in the cavities (12) respectively.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: May 25, 2021
    Inventor: Cheng Yu Huang
  • Archery bow support device
    Patent number: 11009308
    Abstract: An archery bow support device is disclosed having a clip portion have a front leg having a front surface and a back leg and a support bracket connected to the front surface of the front leg and extending outwardly from the front leg. An archery bow support device having a clip portion have a front leg having a front surface and an end portion and a back leg and a support bracket connected to the end portion of the front leg by a hinge device for allowing the support bracket to pivot relative to the front leg and the support bracket extending outwardly from the front leg is also disclosed.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: May 18, 2021
    Inventor: Jason Ochs
  • Crystalline form of an avibactam derivative
    Patent number: 11008321
    Abstract: A crystalline form of an avibactam derivative, pharmaceutical compositions thereof, and the use of the crystalline avibactam derivative for treating bacterial infections are provided.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: May 18, 2021
    Assignee: Arixa Pharmaceuticals, Inc.
    Inventor: Sami Karaborni
  • Process to obtain a tetrahydroisoquinoline derivative
    Patent number: 11001574
    Abstract: The present invention relates to a process for preparing lifitegrast or a salt thereof, wherein the process comprises hydrogenation of compound II in a mixture comprising at least one solvent selected from the group consisting of acetonitrile, a ketone solvent, an ester solvent and a mixture thereof, preferably acetonitrile.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: May 11, 2021
    Assignee: Medichem S.A.
    Inventors: Zhu Bin, Rao Lingxiang, Jordi Puig Serrano, Ernesto Durán López
  • Polymorphs
    Patent number: 11001584
    Abstract: The present invention relates to solid forms of the insecticide of formula I: I, compositions comprising the solid forms and methods of their use as insecticides.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: May 11, 2021
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: Ian Kevin Jones, John Hone, Neil George
  • Process for preparing N-(5-(3-(7-(3-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide
    Patent number: 10981909
    Abstract: Provided herein is a synthetic process for preparing a compound of Formula (1). The disclosure also provides useful intermediates and salts, amorphous and polymorph forms of the compound of Formula (1). These compounds are useful for various disease including cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, and osteoarthritis as well as Wnt-related diseases.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: April 20, 2021
    Assignee: Samumed, LLC
    Inventor: Sunil Kumar Kc
  • Process for the preparation of epoprostenol sodium of enhanced stability
    Patent number: 10981884
    Abstract: The invention provides a stable epoprostenol sodium and a process for the preparation this pharmaceutically active ingredient.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: April 20, 2021
    Assignee: CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE COMPANY LTD.
    Inventors: Irén Hortobágyi, István Lászlófi, Zsuzsanna Kardos, József Molnár, László Takács, Róbertné Tormási
  • Nicotinic acid or isonicotinic acid compound and use thereof
    Patent number: 10981873
    Abstract: Disclosed are a nicotinic acid or isonicotinic acid compound and a use thereof. The compound is the compound shown in Formula I, or a pharmaceutically acceptable salt, ester or solvate thereof. Efficacy tests demonstrate that the nicotinic acid compound can inhibit botulinum toxin endopeptidase activity in vitro, and has a significant protective effect on mice poisoned with botulinum toxin. On this basis, the compound may be used to prepare a drug preventing and/or treating botulinum toxin exposure and/or poisoning.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: April 20, 2021
    Assignee: ACADEMY OF MILITARY MEDICAL SCIENCES
    Inventors: Hui Wang, Tao Li, Zhenyuan Miao, Jianxin Wang, Deyan Luo, Jie Huang, Chunlin Zhuang, Yuelin Wu
  • Toothbrush package
    Patent number: D917298
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: April 27, 2021
    Assignee: The Gillette Company LLC
    Inventors: Christine Hallein, Dominik Langhammer
  • Boat-shaped receptacle
    Patent number: D917299
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: April 27, 2021
    Inventor: Rafael Augusto Lozano
  • Incense carton
    Patent number: D919423
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: May 18, 2021
    Inventor: Thomas Stephen Eldridge