Patents Examined by Lance Rider
  • Patent number: 8409619
    Abstract: An oral drug delivery system for treatment of tuberculosis is described. The oral drug delivery system includes (e.g., a mixture or combination of): poly DL-lactide-co-glycolide nano particles having encapsulated an azole therein; poly DL-lactide-co-glycolide nano particles having moxifloxacin encapsulated therein; and poly DL-lactide-co-glycolide nano particles having RIF encapsulated therein.
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: April 2, 2013
    Assignee: Lifecare Innovations Pvt. Ltd.
    Inventors: Gopal Krishan Khuller, Jitendra Nath Verma
  • Patent number: 8404751
    Abstract: Onychomycosis is a fungal infection of the nail bed and is difficult to treat topically because penetration of the nail plate is difficult, and systemic antifungal treatments are prone to side effects and drug interactions. The present invention treats onychomycosis by applying an antifungal composition to the nail bed directly using a solid, semi-solid, or flowable carrier. The carrier can be in the form of a semi-solid into which the user digs and scrapes the nail, a solid carrier can be inserted directly under the nail in contact with the nail bed, or a flowable composition can be injected in contact with the nail bed.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: March 26, 2013
    Assignee: Hallux, Inc.
    Inventors: Jay E. Birnbaum, Keith A. Johnson
  • Patent number: 8399007
    Abstract: Methods for making formulations of drugs and crystalline side chain polymers which formulations provide controlled and/or sustained release drug formulations.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: March 19, 2013
    Assignee: Landec Corporation
    Inventors: David Taft, Stelios Tzannis, Wei-Guo Dai, Sandra Ottensmann, Steven Bitler, Qiang Zheng, Adam Bell
  • Patent number: 8398960
    Abstract: The invention relates to agents for temporarily shaping keratin fibers, said agents giving a very high degree of hold without impairing its flexibility and humidity resistance.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: March 19, 2013
    Assignee: Henkel AG & Co. KGaA
    Inventors: Thorsten Knappe, Rene Scheffler
  • Patent number: 8394416
    Abstract: The present invention relates to a novel one step process for preparing cross-linked poly(allylamine) polymers or salts thereof using the novel cross-linking agent of Formula (IV). This invention also relates to the compound of Formula (IV) as well as to a process to obtain it. The cross-linked poly(allylamine) polymers of the invention are useful in medicine as substrate-binding polymers.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: March 12, 2013
    Assignee: Chemo Ibérica, S.A.
    Inventors: Sabrina Bianchi, Valter Castelvetro, Giovanni Marras, Sonja Bellomi, Graziano Castaldi, Gianpiero Ventimiglia
  • Patent number: 8268766
    Abstract: The present invention relates to a series of polyglycoside derivatives that are (a) polymeric (that is cross linked with hydroxypropyl linkages) and (b) contain additional functional groups including alkoxy, sulfate, sulfonate, quaternary and phosphate groups, and (c) sorbitan esters to increase oil solubility and provide outstanding emulsifiers.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: September 18, 2012
    Assignee: Surfatech Corporation
    Inventor: Anthony J. O'Lenick, Jr.
  • Patent number: 8246999
    Abstract: The invention provides an article comprising, a mesoporous silicate matrix, such as a particle, having one or more pores; and one or more releasable caps obstructing one or more of the pores. The articles are useful as delivery vehicles for encapsulated agents such as therapeutic agents, polynucleotides, polypeptides and the like.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: August 21, 2012
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Victor Shang-Yi Lin, Cheng-Yu Lai, Srdija Jeftinija, Dusan M. Jeftinija
  • Patent number: 8202524
    Abstract: The present invention relates to a method for producing polymeric microspheres loaded with drugs and polymeric microspheres loaded with drugs produced thereby, specifically a method for producing polymeric microspheres loaded with drugs, the method comprising the steps of a) adding a dispersion phase containing a high molecular compound, a drug, and a water-insoluble organic solvent to a dispersion solvent to produce an O/W (oil-in-water) type or O/O (oil-in-oil) type emulsion, or adding a W/O (water-in-oil) type emulsion, which is prepared by emulsifying an aqueous solution, in which a drug is dissolved, in a water-insoluble organic solvent, in which the high molecular compound is dissolved, to the dispersion solvent to produce a W/O/W (water-in-oil-in-water) type emulsion; and b) adding an ammonia solution to the emulsion produced in step a) to convert the water-insoluble organic solvent into water-soluble solvents, and polymeric microspheres loaded with drugs produced thereby.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: June 19, 2012
    Assignees: SK Chemicals Co., Ltd., EWHA University-Industry Collaboration Foundation
    Inventor: Hong Kee Sah
  • Patent number: 8142766
    Abstract: A gel composition for removal of unwanted human hair from human skin that is comprised of a mixture of a majority portion of sugar and minor portions of lemon juice and water. The portions of sugar and lemon juice are initially heated to an appropriate temperature over a sufficient duration at which time the minor portion of water is added to the mixture. After adding water to the first mixture, the second mixture with water is heated until a composition of gel-like consistency has been produced. The composition is applied by hand or utensil to a part of human skin with unwanted hair and then covered with an absorbent layer of cloth until the unwanted hair has been dissolved by the composition at which time the cloth is removed from the skin with the composition absorbed therein and unwanted hair attached thereon.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: March 27, 2012
    Inventor: Yasmin Azra Bhatti
  • Patent number: 8063026
    Abstract: Provided herein are methods of using mannan oligosaccharides, to treat, palliate, relieve, prevent and/or eliminate urinary tract infections of humans. A mixture of oligosaccharides derived from yeast cell walls is shown to reduce, eliminate and prevent the symptoms of UTI in patients.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: November 22, 2011
    Inventor: Richard Katz
  • Patent number: 8012455
    Abstract: The present invention provides an integral source material, the integral source material has at least one nuclide that is an integral source material having at least one nuclide that is activatable by exposure to radiation, the nuclide is a chemically bound constituent of a polymer of the integral source material, wherein the integral source material is configured before activation to provide a device.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: September 6, 2011
    Assignee: Civatech Corporation
    Inventor: Fearghus O'Foghludha
  • Patent number: 7910561
    Abstract: The present invention is directed to compounds which contain substituted naphthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention. These substituted naphthyridines have unexpected advantageous properties when compared to other naphthyridines reported in PCT publication WO2003/086394, such unexpected advantageous properties may include increased cellular potency/solubility, greater selectivity, enhanced pharmacokinetic properties, lack of off target activity and so on.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: March 22, 2011
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Jeannie M. Arruda, Brian T. Campbell, Nicholas D. P. Cosford, Jacob M. Hoffman, Essa H. Hu, Mark E. Layton, Yiwei Li, Jun Liang, Kevin J. Rodzinak, Tony Siu, Brian A. Stearns, Lida R. Tehrani, Mark T. Bilodeau, Peter J. Manley
  • Patent number: 7883723
    Abstract: The present invention relates to a water soluble chitosan nanoparticle (WSC-NP) for delivering an anticancer agent and a preparing method thereof, more precisely, a water soluble chitosan nanoparticle for delivering an anticancer agent which has function of targeting on a wanted area by introducing a functional group in the location of highly reactive amine group and becomes an excellent gene carrier with the use of water soluble chitosan since the water soluble chitosan itself can combined with DNA having a negative electric charge(?) owing to the very strong positive electric charge(+) of its amine group, and a preparing method thereof. Therefore, a water-soluble chitosan nanoparticle for delivering an anticancer agent of the present invention can effectively envelope paclitaxel by introducing hydrophilic and hydrophobic groups in the position of highly reactive amine group of the water-soluble chitosan.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: February 8, 2011
    Inventors: Jae-Woon Nah, Teok Rae Jung, Mi-Kyeong Jang, Young-Il Jeong
  • Patent number: 7842281
    Abstract: Magnetic nanoparticle compositions are provided which provide an inherent temperature regulator for use in magnetic heating, particularly for use in magnetic hyperthermia medical treatments. The composition includes magnetic nanoparticles having a Curie temperature of between 40 and 46° C., preferably about 42° C., and may further include a polymeric material and optionally a drug or radiosensitizing agent. Methods of hyperthermia treatment of a patient in need thereof are provided which include the steps of administering to the patient a composition comprising magnetic nanoparticles having a Curie temperature of between 40 and 46° C.; and exposing the magnetic nanoparticles in the patient to an alternating magnetic field effective to generate hysteresis heat in the nanoparticles.
    Type: Grant
    Filed: May 10, 2005
    Date of Patent: November 30, 2010
    Assignee: The Florida State University Research Foundation
    Inventors: Yousef Haik, Ching-Jen Chen
  • Patent number: 7744853
    Abstract: Radiolabeled annexin and modified annexin conjugates useful for imaging vascular thrombi are described. Methods for making and using such radiolabeled annexin conjugates are also provided.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: June 29, 2010
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventors: Sudhakar Kasina, John M. Reno, Alan R. Fritzberg, Jonathan Tait