Abstract: A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture of sucrose esters of coconut fatty acids, which is predominantly sucrose monolaurate. Preferred embodiments of therapeutic systems for delivering the drug and the sucrose ester employ a matrix containing drug at a concentration above saturation.

Abstract: Isolated chlorogenic acid or the physiologically acceptable derivatives thereof when used before or simultaneously with the administration of gastric acid secretion-stimulating and/or gastric mucosa-irritating or attacking foods, beverages and/or medicaments lead to a reduction of gastric acid secretion and/or to the protection of the gastric mucosa.

Abstract: A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.

Abstract: Microencapsulated drugs are employed for introduction into the chambers of the eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.

Abstract: The instant invention is directed to a multiparticulate osmotic pump, for the controlled release of a pharmaceutically active agent to an environment of use, said pump comprising:(I) a carrier medium which does not maintain its integrity in the environment of use;(II) a multiple of tiny osmotic pump elements each consisting essentially of:(A) a core comprises at least one pharmacologically active agent soluble in an external fluid, or a mixture of an agent having a limited solubility in the external fluid with an osmotically effective solute that is soluble in the fluid, which exhibit an osmotic pressure gradient across the wall against the external fluid surrounded by(B) a rate controlling water insoluble wall, having a fluid permeability of 6.96.times.10.sup.-18 to 6.96.times.10.sup.14 cm.sup.3 sec/g and a reflection coefficient of less than 0.5, prepared from:(i) a polymer permeable to water but impermeable to solute and(ii) 0.

Abstract: A method for manufacturing an electric resistance element first prepares carbon particles by thermally treating these particles, such as carbon black at a temperature of at least 300.degree. C. Then a separate mixture of the carbon particles in an epoxy resin is prepared by mixing the carbon particles with a solution of an amino resin to at least partially cause adsorption, occlusion or reaction between the carbon particles and the amino resin. Then the amino resin is polymerized by heating. A further mixture is prepared by mixing a solution of epoxy resin with the first mixture to prepare a paste material which is then coated onto the surface of a substrate. The coating is then thermally cure to form a resistance film on the surface of the substrate.

Abstract: Disclosed is a novel process to prepare a solid product containing an oil-soluble substance (e.g. oil and fat, spice, flavor, vitamin, emulsifier, hormone, higher fatty acid, unsaponifiable substance and complex lipid), comprising adding to an oil-soluble liquid substance an anhydrous maltose (e.g. anhydrous crystalline alpha-maltose, anhydrous crystalline beta-maltose and anhydrous amorphous maltose) along with water, and crystallizing beta-maltose hydrate in the mixture.

Abstract: This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.

Abstract: Topically applicable formulations comprising known ciprofloxacin-type antibacterials of the formula ##STR1## in whichA is N or C-R.sup.9,and corticosteroids are especially effective in therapy, particularly in the oral cavity. The formulations can be used in the form of plasters, gels, suspensions, emulsions and solutions.

Abstract: A wound-healing preparation is composed of 50-90 wt. % of a sugar, 0.5-10 wt. % of povidone-iodine, and 1-20 wt. % of water. A buffer is also contained in an amount sufficient to adjust the pH of the preparation to 3.5-6. Preferably, the preparation may additionally contain 0.1-5 wt. % of an agent for imparting an appropriate consistency and stability, which is selected from polysaccharides and derivatives thereof.

Abstract: A granular agent for a ruminant comprising a solid substance containing at least one physiologically active substance coated with a thin film of a waxy substance having a melting point of 40.degree. C. to 120.degree. C., the thin film having a thickness of 0.2 to 20 .mu.m and containing therein fine solid particles having a melting point of 120.degree. C. or more and an average particle size of 10 .mu.m or less and the fine solid particles being substantially slightly soluble in water and insoluble in the waxy substance under a neutral condition.

Abstract: Apparatus and a method for inhibiting the metabolism of methanol in a human. The apparatus comprises carrier means for a source of ethanol. The carrier means, when combined with a source of ethanol and introduced in the digestive tract of a human being, permits the gradual time release of ethanol from the dietary vaccine into the digestive tract for absorption into the blood stream of an individual. The method comprises introducing the ethanol charged carrier means in the digestive tract of an individual.

Abstract: An anti-inflammatory analgesic adhesive preparation is disclosed, comprising a flexible support having laminated thereon a pressure-sensitive adhesive material layer which contains Diclofenac Sodium and an organic acid such as citric acid. This adhesive preparation has excellent percutaneous absorption properties.

Abstract: This invention relates to etoposide solution preparations, which exhibit excellent absorbability in vivo, comprising a container and, enclosed therein, an etoposide solution composition containing etoposide and a water-soluble cellulose derivative or polyvinylpyrrolidone.

Abstract: A method for selectively applying light-absorbing particles to a lenticular, light-transmissive screen, such as a projection television screen. The particles are charged and are selectively deposited in grooves between lenticules of the screen by electrically charging the lenticule peaks to the same polarity, to effect repulsion, and then depositing the particles onto the screen. The particles consist essentially of a material having a substantially higher microwave absorption coefficient than the screen material and have heat-fusible outer surfaces. After deposition, the particles are selectively heated by generally-applied microwave radiation, until they fuse to each other and to the screen.

Abstract: In a process for protecting polished silicon surfaces, after an oxidative eaning is carried out, the surface is coated with a protective layer by the action of a reagent especially hexamethyldisilazane which permits trialkylsilylation. The layer prevents aging of the oxide layer even over several months storage. Before subsequent processing steps, the protective layer can easily be removed again by thermal oxidation, without forming interfering by-products.

Abstract: Nickel-free aqueous phosphating compositions containing zinc ions, cobalt ions, phosphate ions, and at least two additional cations; methods for using such composition, and products of the methods.

Abstract: A method of improving the adhesion of silicone elastomers, obtained from aqueous emulsions, comprises mixing the emulsion with an amine functional co-oligomer. A preferred co-oligomer is of the formula ##STR1## where R is a monovalent alkyl radical of from 1 to 6 carbon atoms, x is from 1 to 250, and y is from 2 to 50.

Abstract: Conformal layers of a silicon oxide, such as silicon dioxide, are deposited at temperatures below 600 degrees C. through the decomposition of compounds such as diacetoxyditertiarybutoxysilane. The required temperatures do not significantly affect temperature-sensitive structures. Therefore, it is possible to form silicon oxide regions in the processing of devices having these structures. More generally, lowered-temperature processing can be applied to the deposition of other materials which include silicon oxide. For example, borophosphosilicate glasses can be deposited by chemical vapor deposition processing involving flash-evaporation of a mixture of liquid precursor reagents.

Abstract: In a method and apparatus for coloring polymer-insulated wire, the wire is guided through a solvent reservoir to dissolve surface contaminants and etch the surface of the insulation, and passed between opposed wiping surfaces to wipe surface contaminants from the wire. The wire is then passed through a hot air duct to evaporate solvent remaining on its surface. The dried wire is guided through a solvent-based colorant reservoir to coat it with colorant and passed against a wiping surface to wipe excess colorant from its surface. The coated wire is passed through a hot air duct to evaporate some of the solvent in the colorant, and through a cold air duct to harden an outer surface of the colorant before it passes over a guide wheel. The hardened surface prevents adherence of the colorant to the guide wheel. The coated wire is passed by a spraying device which intermittently sprays solvent-based colorant on the wire to band encode it.