Patents Examined by Leslie R. Deak
  • Patent number: 12257188
    Abstract: A system for preparation of an implant and ab interno insertion of the implant into an eye including a handle having one or more actuators and an elongated shaft having an outer sheath and an elongate member positioned within a lumen of the tubular outer sheath. The system includes a recess sized for holding a patch of material fixed relative to the handle and a cutting member movable relative to the handle and to the recess. The cutting member cuts the patch of material into an implant as the cutting member moves towards a cutting configuration. The implant, once cut, is axially aligned with the lumen of the tubular outer sheath. The inner elongate member is movable relative to the tubular outer sheath to advance the implant into a deployment position in the lumen of the tubular outer sheath for delivery into the eye. Related devices and methods are provided.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: March 25, 2025
    Assignee: Iantrek, Inc.
    Inventor: Tsontcho Ianchulev
  • Patent number: 12245985
    Abstract: An apparatus for drawing medicine from a medicine container into a syringe is disclosed. The apparatus includes a base, and support frames extending from the base. The apparatus includes a top platform and a bottom platform. The bottom platform includes a fixed platform and a moveable platform. The moveable platform operably extends and retracts into the fixed platform along the support frames at the bottom of the fixed platform. The top platform positions above the bottom platform and receives a medicine container facing the bottom platform. The medicine container stores medicine. The fixed platform is configured to hold a flange of a syringe, and the moveable platform is configured to hold a plunger of the syringe. The moveable platform slides down from the fixed platform along the support frames engaging the plunger. The movement of the moveable platform draws medicine from the medicine container into the syringe.
    Type: Grant
    Filed: November 4, 2024
    Date of Patent: March 11, 2025
    Inventor: James C. Wilson
  • Patent number: 12245781
    Abstract: A system is provided which includes a cannula and a secondary device. The cannula includes an expandable member, a cannula lumen, and a cannula proximal end. The expandable member includes a proximal most end, a distal most end, at least two movable sections, with the space between the at least two moveable sections, and an impermeable membrane extending across the space between each of the at least two moveable sections. In addition, the impermeable membrane extends from the expandable member distal most end to the expandable member proximal most end. The secondary device is configured to be coaxially placed through the cannula lumen. The cannula proximal end is configured to operatively couple to a vacuum source configured to create a negative pressure to pull an undesirable material into the cannula lumen.
    Type: Grant
    Filed: May 23, 2024
    Date of Patent: March 11, 2025
    Assignee: AngioDynamics, Inc.
    Inventors: Lishan Aklog, Michael Glennon
  • Patent number: 12233189
    Abstract: An artificial lung system for a patient having a membrane lung system having an gas inlet, a blood inlet, a blood outlet, and an exhaust; a gas system operably coupled to the gas inlet of the membrane lung system; a gas phase CO2 sensor disposed downstream of the exhaust of the membrane lung system and monitoring an exhaust gas CO2 (EGCO2) level and/or an blood oxygen saturation sensor disposed upstream of the blood inlet of the membrane lung system and monitoring a blood oxygen saturation level; and a feedback controller receiving the CO2 signal and/or blood oxygen saturation signal and outputting a control signal to control gas flow and/or blood flow.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: February 25, 2025
    Assignees: The Regents of The University of Michigan, United States Government As Represented by the Department of Veterans Affairs
    Inventors: Joseph Potkay, Robert H. Bartlett, Alvaro Rojas-Pena
  • Patent number: 12226308
    Abstract: Some embodiments disclosed herein relate to devices and methods for controlling placement of intraocular implants within a patient's eye including but not limited to placement within or near the collector ducts of Schlemm's canal located behind the trabecular meshwork. In some embodiments, a handheld peristaltic rotor device having a compression element can be positioned on a corneal surface of the eye and rotated to create a peristaltic movement of blood in one or more episcleral veins to generate blood reflux within Schlemm's canal such that one or more collector ducts, or channels, of Schlemm's canal can be located. In some embodiments, an implant can be implanted near the identified location of the one or more collector ducts, or channels.
    Type: Grant
    Filed: August 12, 2021
    Date of Patent: February 18, 2025
    Assignee: Glaukos Corporation
    Inventor: Charles Raymond Kalina, Jr.
  • Patent number: 12226343
    Abstract: Systems and devices for facilitating the flow of fluid between a first body region and a second body region are disclosed herein. The devices generally include a drainage and/or shunting element having a lumen extending therethrough for draining or otherwise shunting fluid between the first and second body regions. Further, devices configured in accordance with the present technology may be selectively adjustable to control the amount of fluid flowing between the first and second body regions. In some embodiments, for example, the devices comprise an actuation assembly that drives movement of a flow control element to modulate flow resistance through the lumen, thereby increasing or decreasing the relative drainage rate of fluid between the first body region and the second body region.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: February 18, 2025
    Assignee: Shifamed Holdings, LLC
    Inventors: Colin Mixter, Claudio Argento, Andrew Backus, Tom Saul
  • Patent number: 12220350
    Abstract: Adjustable flow glaucoma shunts are disclosed herein. In one embodiment, for example, an adjustable flow shunt can include an outflow drainage tube having a proximal inflow region and a distal outflow region. The proximal inflow region can include aperture(s) defining a fluid inlet area positioned to allow fluid to flow therethrough. The shunt further comprises an inflow control assembly at the proximal inflow region. The inflow control assembly can include a control element configured to slidably engage the proximal inflow region and a spring element. The spring element is configured to be activated by non-invasive energy and, upon activation, slidably move the control element along the proximal inflow region such that (a) the one or more apertures are accessible and have a first fluid flow cross-section or (b) the one or more apertures are at least partially covered by the control element and have a second, different fluid-flow cross-section.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: February 11, 2025
    Assignee: Shifamed Holdings, LLC
    Inventors: Colin Mixter, Claudio Argento, Andrew Backus, Tom Saul
  • Patent number: 12214145
    Abstract: Provided is foley catheter and a composition for producing a foley catheter which is inserted in vivo and a method for producing the same, which the composition consists of the materials which carbon nanotube polymer (CNT Polymer) bonded a carbon nanotube and zinc oxide (ZnO) is combined with a silicon, wherein from 1.0 to 2.2 parts by weight of the said carbon nanotube polymer are combined with 100 parts by weight of silicon.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: February 4, 2025
    Assignee: AP MDS Co., Ltd.
    Inventors: Jong Jeong Kim, Yong Han Chun
  • Patent number: 12213945
    Abstract: A cap assembly includes an access member configured for attachment to a reservoir. The access member includes a first port that enables needleless extraction of contents from the reservoir, and at least one second port that enables needled extraction of the contents from the reservoir. The cap assembly further includes a valve member positioned in or configured to be positioned in the access member to i) enable needleless extraction of the contents of the reservoir through the first port when the first port is attached to a needless extraction device, ii) enable needled extraction of the contents through the at least one second port, and iii) seal the contents of the reservoir at the first port and at the at least one second port prior to and subsequent to the needleless or needled extraction.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: February 4, 2025
    Assignee: KLIM-LOC, LLC
    Inventor: Robbie Klimek
  • Patent number: 12208034
    Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: January 28, 2025
    Assignee: Dose Medical Corporation
    Inventors: David S. Haffner, Thomas W. Burns, Harold A. Heitzmann, Kenneth M. Curry
  • Patent number: 12201584
    Abstract: A blood storage container for the anaerobic storage of blood, having enhanced sealing methods and materials for the preservation of stored blood is provided.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: January 21, 2025
    Assignee: Hemanext Inc.
    Inventors: Tatsuro Yoshida, Rafael Cordero, Jancarlo Sarita, Michael Zocchi, Michael Wolf, Philip Michael Keegan, Narendran Renganathan, Jeffrey Karl Sutton
  • Patent number: 12194216
    Abstract: Devices and methods establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures performed through a transcarotid approach or transfemoral into the common carotid artery.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: January 14, 2025
    Assignee: Silk Road Medical, Inc.
    Inventors: Stewart M. Kume, Sieu T. Duong, Michi E. Garrison
  • Patent number: 12194212
    Abstract: An extracorporeal blood cooling or heating circuit includes an intravenous catheter for withdrawing a patient's blood coupled to a combined pump/heat exchanger device. One or more sensors are provided upstream and/or downstream of the pump/heat exchanger device for measuring pressure, temperature, fluid flow, blood oxygenation, and other parameters, A controller is operative!}? coupled to the pump/heat exchanger device and the one or more sensors to control the speed of the pump inside the pump/heat exchanger device and regulate the blood temperature by controlling the operation of the heat exchanger. The combined pump/heat exchanger device includes a housing having at least one inlet and at least one outlet, a pump portion defining a blood circuit inside the housing, and a heat exchanger portion contained within the housing for selectively heating or cooling the blood.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: January 14, 2025
    Assignee: CardiacAssist, Inc.
    Inventors: Robert G. Svitek, Kraig J. McEwen, Rebecca L. Baptiste
  • Patent number: 12186474
    Abstract: A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: January 7, 2025
    Assignee: Haemonetics Corporation
    Inventor: Michael Ragusa
  • Patent number: 12171916
    Abstract: A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: December 24, 2024
    Assignee: Haemonetics Corporation
    Inventor: Michael Ragusa
  • Patent number: 12171917
    Abstract: A blood reintroduction system may include a canister configured to collect blood. The system may include an inlet configured to be fluidly connected to a first tubing in fluid communication with an aspiration system configured to apply aspiration to a vasculature of a patient. The system may include a first outlet configured to be fluidly connected to a second tubing in fluid communication with an aspiration pump. The system may include a second outlet configured to interact with a blood reintroduction device, wherein the blood reintroduction device is configured to withdraw the blood collected inside the canister. The system may include a filter positioned inside a flow path leading to the second outlet.
    Type: Grant
    Filed: January 8, 2024
    Date of Patent: December 24, 2024
    Assignee: Imperative Care, Inc.
    Inventors: Michael Buck, Julia Fox, James Jacobs
  • Patent number: 12168088
    Abstract: A dialysis device implantable in a patient for dialysis includes a filtration unit. The filtration unit includes at least one dialysis chamber for containing and/or circulating dialysate; and at least one blood chamber for containing and/or circulating blood of the patient, disposed on at least one dialysis chamber and being in communication with the at least one dialysis chamber. Each of the at least one dialysis chamber and the at least one blood chamber comprise at least one inlet for circulating fluid into and/or out of the at least one dialysis chamber and the at least one blood chamber. The at least one dialysis chamber and the at least one blood chamber are configured such that the blood in the at least one blood chamber and the dialysate in the at least one dialysis chamber operably interact with each other for dialysis.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: December 17, 2024
    Assignee: NEPHRODITE LLC
    Inventors: Hiep Nguyen, Nikhil Shah, Julie Wilderman
  • Patent number: 12168783
    Abstract: A system and method for preparing a cancer vaccine (and optionally purifying the blood) has a blood filtration system, controlled by a processing unit, for filtering exogenous blood plasma to isolate tumor cells, tumor stem cells and tumor breakdown products. The blood filtration system filter may include multiple layers having differently sized apertures to retain differently sized materials (from among tumor cells of different sizes, tumor stem cells and tumor breakdown products. A device directs electromagnetic radiation at the separated tumor cells, tumor stem cells and/or tumor breakdown products. The electromagnetic radiation may cause the separated tumor cells, separated tumor stem cells and/or separated tumor breakdown products (for example tumor protein such as DNA and/or tumor exosomes) to have a coagulated outer layer such as by degrading the outer surface. The electromagnetic radiation may have a UV wavelength. A conical coil improves flow rate uniformity. Tumor exosomes may be centrifuged.
    Type: Grant
    Filed: October 17, 2023
    Date of Patent: December 17, 2024
    Inventors: David Michaeli, Menashe Michaeli
  • Patent number: 12161791
    Abstract: A method of treating blood withdrawn from patient including: simultaneously withdrawing blood and infusing withdrawn blood from and to the patient by flowing the withdrawn blood through an extracorporeal dialysis circuit including a dialyzer having a semi-permeable dialysis membrane and a dialysate side adjacent the membrane; feeding a dialysate containing 1 to 5 mM total calcium and 2 to 8 mM citrate to the dialysate side of the dialyzer, and introducing an anticoagulation fluid including at least 8 mM citrate into the withdrawn blood upstream of the dialyzer.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: December 10, 2024
    Assignee: GAMBRO LUNDIA AB
    Inventor: Jan Sternby
  • Patent number: 12156961
    Abstract: Devices and methods establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures performed through a transcarotid approach or transfemoral into the common carotid artery.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: December 3, 2024
    Assignee: Silk Road Medical, Inc.
    Inventors: Stewart M. Kume, Sieu T. Duong, Michi E. Garrison