Abstract: A ventricular catheter assembly including a proximal catheter and a cooperating cranial cover. The cranial cover includes a base plate having an opening aligned with a burr hole in the skull of a person. A guide extends upwardly from the base plate and receives the proximal catheter.

Abstract: The invention relates to a blood treatment device having at least one metering line which opens into a fluid circuit, wherein a conveyor module is arranged in the metering line and comprises a membrane pump and a valve which is arranged at the pressure side thereof and which can act both as a blocking valve and as a restricting valve.

Abstract: A device that can be placed within or near the cranial vault that fluctuates in size in response to changes in CSF pressure is disclosed. The device diminishes in size when CSF pressures rise and increases in size as CSF pressures diminish. The device has the effect of reducing the flow of CSF occurring in the foramen magnum and provides an alternative to craniovertebral decompression in Chiari I patients. The device may have applications in other neurologic illnesses associated with abnormal CSF flow, such as Idiopathic Syringomyelia, Normal Pressure Hydrocephalus, and CSF dural leaks.

Abstract: A extracorporeal system for lung assist includes a housing, a blood flow inlet in fluid connection with the housing; a blood flow outlet in fluid connection with the housing; a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between blood and an interior of the hollow gas permeable fibers, the plurality of hollow gas permeable fibers being positioned between the blood flow inlet and the blood flow outlet such that blood flows around the plurality of hollow gas permeable fibers when flowing from the blood flow inlet to the blood flow outlet; a gas inlet in fluid connection with the housing and in fluid connection with inlets of the plurality of hollow gas permeable fibers; a gas outlet in fluid connection with the housing and in fluid connection with outlets of the plurality of hollow gas permeable fibers; and at least one moving element to create velocity fields in blood flow contacting the plurality of hollow gas permeable fibers.

Abstract: The invention relates to a fluid valve and fluid connection system, comprising a casing having a chamber with a first internal connection element and a first external connection element; comprising a first movable valve element in the chamber; and comprising an actuating element which has a fluid communication system with a second internal connection element and a second external connection element; wherein the first internal connection element cooperates with the second internal connection element and the valve element to establish or block a fluid connection between the first and second external connection elements.

Abstract: The present technology relates to intraocular shunting systems and methods. In some embodiments, the present technology includes intraocular shunting systems that include a drainage element having an inflow portion configured for placement within an anterior chamber of the eye outside of an optical field of view of the patient and an outflow portion configured for placement at a different location of the eye. The system can also include a flow control assembly having a rotational control element operably coupled to the drainage element. The flow control assembly can further include an actuation structure coupled to the rotational control element and configured to selectively change an orientation of the rotational control element. An amount of fluid through the inflow portion and/or the outflow portion can vary based on the selected orientation of the rotational control element.

Abstract: The present invention provides a novel shunt device and methods of use, and in particular a cerebral shunt device. The cerebral shunt device includes an outer tube member forming a first lumen, the outer tube member having a drainage outlet and at least one opening to the first lumen in a distal region along the length of the outer tube member. The shunt also includes an inner tube member forming a second lumen, the inner tube member having at least one opening to the second lumen along the length of the inner tube member. The inner tube member is positioned within the first lumen and a pump unit fluidly connected to the second lumen to force fluid from the first lumen, which clears obstructions in the shunt.

Abstract: The present disclosure relates to a blood treatment apparatus having of each at least one control device; one user interface; one receiving section for releasably receiving an organizer, wherein the organizer comprises components releasably connected thereto for the extracorporeal blood treatment options, in particular dialysis method being executable by the blood treatment apparatus, wherein the blood treatment apparatus comprises in particular in the area of its reception section or in the area corresponding thereto a device for the releasable fastening or fixing of the organizer (on)to the blood treatment apparatus and/or at least a device for acting on components of an organizer which is releasably received in or on the receiving section. Furthermore, an organizer is specified.

Abstract: The present invention provides a method, system, and apparatus that can substantially reduce the recirculation of venovenous extracorporeal membrane oxygenation (VV ECMO) associated with the two-site, single-lumen cannulation approach. Actively-controlled flow regulators comprising balloon, occluder and reservoir can be individually or collectively equipped on the drainage and/or infusion cannulas to accomplish the goal of maximizing VV ECMO support efficacy. Three specific embodiments are introduced to illustrate the practical enforcement of the proposed blood flow control in reference to the heart rhythm, aiming at achieving the maximal reduction of oxygenated blood flow recirculating back to the VV ECMO circuit.

Abstract: Example aspects of a medication holding device and a method for using a medication holding device are disclosed. The medication holding device can comprise a mount and a grip coupled to the mount, the grip defining a channel, the grip movable between an open position and a closed position, the channel defining a first width in the closed position, the channel defining a second width in the open position that is greater than the first width.

Abstract: Cerebrospinal fluid (CSF) and other fluid amelioration systems completely or partially implantable within a mammalian subject and associated methods include a substrate and an agent for amelioration of a toxic biomolecule present in the CSF or fluid, wherein the agent is disposed on or within the substrate.

Abstract: A system includes a vial access device including a vial access housing having a wall defining an elongate opening between an opening proximal end and an opening distal end, the vial access housing including a spike and a vial connection element attachable to a first vial defining a first vial size to secure the vial access device to the first vial, and an adapter movable within the elongate opening of the vial access housing. The adapter is transitionable between a first position where the adapter is adjacent the opening distal end of the vial access housing and the adapter is attachable to a second vial defining a second vial size and a second position where the adapter is adjacent the opening proximal end of the vial access housing and the vial connection element of the vial access device is attachable to the first vial.

Abstract: To provide a concentration calculating module configured to measure the concentrations of two constituents simultaneously with higher accuracy. The concentration measuring module includes a light source configured to emit light into a housing; a first light receiving unit configured to have sensitivity to a wavelength of output light of the light source and receive light radiated from inside the housing; and a second light receiving unit configured to have sensitivity to a longer wavelength than the first light receiving unit and receive light radiated from inside the housing.

Abstract: An implantable drainage device is provided. The device is adapted to move body fluid from one part of the body of a patient to another part of the body.

Abstract: Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Abstract: The invention relates to a dialysis machine having an extracorporeal blood circuit in which a dialyzer, a blood pump, and an arterial pressure sensor are arranged, wherein the dialysis machine furthermore has a compensation device by means of which the set value for the blood flow through the extracorporeal circuit can be corrected to a compensated value using the arterial blood pressure; wherein the dialysis machine furthermore has recognition means which are configured to recognize whether the arterial pressure sensor is connected to the extracorporeal blood circuit or not; and wherein the dialysis machine has an estimator unit which is configured to estimate a value for the arterial blood pressure if it is recognized by the recognition means that the arterial pressure sensor is not connected to the extracorporeal blood circuit.

Abstract: To provide a concentration calculating module configured to measure the concentrations of two constituents simultaneously with higher accuracy. The concentration measuring module includes a light source configured to emit light into a housing; a first light receiving unit configured to have sensitivity to a wavelength of output light of the light source and receive light radiated from inside the housing; and a second light receiving unit configured to have sensitivity to a longer wavelength than the first light receiving unit and receive light radiated from inside the housing.

Abstract: Methods and for treatment of cancer and other diseases including complications from late stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed.

Abstract: An implantable renal replacement therapy device may include: a first catheter configured to be inserted into a blood vessel in a subject's body; a pump in fluid communication with the first catheter, the pump is configured to pump subject's blood from the blood vessel; a filter in fluid communication with the pump, the filter is configured to: receive the subject's blood from the pump, and filter the received blood to provide a filtered blood and a filtrate liquid, wherein the filter is in fluid communication with the first catheter to cause an outflow of the filtered blood from the filter to the blood vessel; and a second catheter in fluid communication with the filter and configured to be inserted into an urinary bladder in the subject's body to cause an outflow of the filtrate liquid from the filter to the urinary bladder.

Abstract: Systems and methods of implanting a vascular access technologies and declotting vascular access technologies, such as vascular access assemblies that facilitate hemodialysis, are provided. The methods can include disposing a first tubular conduit within a patient to access a vascular access assembly within the heart of the patient. The first tubular conduit can be coupled to the vascular access assembly such that the first tubular conduit can be decoupled from the vascular access assembly to evacuate a clot within the vascular access assembly, and then recouple the first tubular conduit to the vascular access assembly.