Patents Examined by Leslie R. Deak
  • Low-profile ventriculoamniotic shunt for fetal aqueductal stenosis
    Patent number: 10744308
    Abstract: The invention relates to an in-utero ventriculoamniotic shunting device that includes a shunt tube (26) composed of polymer composite and having metallic wire embedded therein, one or more anchors (30) composed of superelastic wire, e.g., thermal shape-set nitinol structures, that are mechanically attached to an exterior surface of the shunt tube (26), and a one-way passive valve (32) composed of a thin polymer membrane. The anchors (30) are effective to prevent migration and dislodgement of the shunting device following its deployment, and the valve (32) is effective to prevent the backflow of amniotic fluid (23).
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: August 18, 2020
    Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Yanfei Chen, Young Jae Chun, Stephen Emery, Xinzhu Gu, William Wagner, Stephanie Greene
  • Method for assessing a patient's fluid status and/or sensitivity to fluid removal, controller, and devices
    Patent number: 10737009
    Abstract: The present invention relates to a method for assessing a patient's sensitivity to fluid removal from the patient's vascular system or to fluid replacement or addition with regard to the patient's hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfills at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage device, a computer program product, and a computer program.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: August 11, 2020
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Paul Chamney, Ulrich Moissl, Peter Wabel, Volker Nier, Sebastian Wieskotten
  • Multipart fluid system and a system for regional citrate anticoagulation in an extracorporeal blood circuit
    Patent number: 10709833
    Abstract: A method of treating blood withdrawn from patient including: simultaneously withdrawing blood and infusing withdrawn blood from and to the patient by flowing the withdrawn blood through an extracorporeal dialysis circuit including a dialyzer having a semi-permeable dialysis membrane and a dialysate side adjacent the membrane; feeding a dialysate containing 1 to 5 mM total calcium and 2 to 8 mM citrate to the dialysate side of the dialyzer, and introducing an anticoagulation fluid including at least 8 mM citrate into the withdrawn blood upstream of the dialyzer.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: July 14, 2020
    Assignee: Gambro Lundia AB
    Inventor: Jan Sternby
  • Venous bag clamping mechanism
    Patent number: 10709637
    Abstract: A venous reservoir including a single inlet line clamp capable of partially or completely restricting blood flow to the venous reservoir. The venous reservoir is provided with a rigid back plate or bracket that can accommodate an inlet line capable of joining to at least one blood inlet port. The rigid back plate or bracket can accommodate a clamp capable of completely or partially closing the inlet line containing both the cardiotomy line and the venous line to manually control the blood flow drained from the patient.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: July 14, 2020
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Stefano Spro, Stefano Reggiani, Claudio Silvestri, Francesco Benatti, Adriano Mazzoli
  • Gas exchange composite membranes and methods of use thereof
    Patent number: 10695480
    Abstract: Provided herein is a gas exchange composite membrane and methods of making the same. The gas exchange composite membrane may find use in a method of exchanging gas with blood in a subject in need of blood oxygenation support, which method is also disclosed. Also provided herein are systems and kits that find use in performing the methods of exchanging gas with blood.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: June 30, 2020
    Assignee: The Regents of the University of California
    Inventors: Shuvo Roy, Torin Yeager, Emily Abada, Ajay S. Dharia
  • Implantable biologic stent and system for biologic material shaping, preparation, and intraocular stenting for increased aqueous outflow and lowering of intraocular pressure
    Patent number: 10695218
    Abstract: A system for preparation of an implant and ab interno insertion of the implant into an eye including a handle having one or more actuators and an elongated shaft having an outer sheath and an elongate member positioned within a lumen of the tubular outer sheath. The system includes a recess sized for holding a patch of material fixed relative to the handle and a cutting member movable relative to the handle and to the recess. The cutting member cuts the patch of material into an implant as the cutting member moves towards a cutting configuration. The implant, once cut, is axially aligned with the lumen of the tubular outer sheath. The inner elongate member is movable relative to the tubular outer sheath to advance the implant into a deployment position in the lumen of the tubular outer sheath for delivery into the eye. Related devices and methods are provided.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: June 30, 2020
    Assignee: Iantrek, Inc.
    Inventor: Tsontcho Ianchulev
  • Self-sealing cannula
    Patent number: 10695483
    Abstract: The present invention discloses a self-sealing cannula that through a self-sealing mechanism fixed on the ventricular wall or atrial wall, the cannula body is attached to the self-sealing fixture and blood is drawn into the lumen via an external pump and returned to the circulation system through a separate cannula; in the case of the double lumen cannula embodiment, the blood will be drawn into the drainage lumen of the double lumen cannula and returned through an infusion lumen at the desired location.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: June 30, 2020
    Assignee: University of Maryland, Baltimore
    Inventors: Zhongjun Wu, Bartley P. Griffith, Keshava Rajagopal
  • Method and system for the automated processing of biological fluid during low level alert condition
    Patent number: 10688233
    Abstract: Methods and systems for processing biological fluid are disclosed. The methods and systems allow for processing of biological fluid to continue in the event that certain non-operator-correctable hardware errors of a non-critical nature are detected during such processing.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 23, 2020
    Assignee: Fenwal, Inc.
    Inventors: Amit J. Patel, Samantha M. Planas, Melissa A. Thill
  • Apparatus for exchanging material between blood and a gas/gas mixture
    Patent number: 10682452
    Abstract: The invention relates to an apparatus for exchanging material between blood and a gas/gas mixture, comprising a chamber (1) through which blood can flow and in which a plurality of material-permeable fiber tubes is provided, the gas/gas mixture being flowable through the fiber tubes, blood being flowable around the fiber tubes. At least one deformable element (9) is provided in the chamber (1) in addition to the fiber tubes, through which the gas/gas mixture can flow, this deformable element being deformable and restorable, in particular compressible out of a relaxed shape and restorable to a relaxed shape by pressure fluctuations acting on the at least one element (9) externally, in particular pressure fluctuations transmitted by the blood in the chamber (1).
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: June 16, 2020
    Assignee: ENMODES GMBH
    Inventors: Ralf Borchardt, Tim Kaufmann
  • Vascular access system with reinforcement member
    Patent number: 10682453
    Abstract: A system for providing a continuous flow of blood between two locations in a cardiovascular system of a patient is provided. The system includes a blood conduit having a proximal portion configured to be attached to an artery. The system also includes a distal portion configured to be inserted into a blood vessel at an insertion site and to be advanced there through to a location spaced apart from the insertion site. Moreover, the system includes a reinforcement member positioned at least partially about the blood conduit in at least one of the distal portion, the proximal portion, or a combination thereof.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: June 16, 2020
    Assignee: Merit Medical Systems, Inc.
    Inventors: David Gale, Daniel Tomko, Stacy Arnold, Venkata Katragadda
  • Extended-use valved urinary catheter
    Patent number: 10675435
    Abstract: The disclosure relates generally to an extended use systems and devices for management of bladder function for people with urinary dysfunction. The system includes a catheter and a valve that can control fluid flow. The catheter can be placed inside the bladder using devices that facilitate insertion and extraction. The placement of the catheter can be done by a trained individual such as a patient, as well as a clinician, a nurse, or a caretaker. Once placed inside the bladder, the catheter can be fully-internal, meaning no portion of the catheter is visible from outside of the patient's body.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: June 9, 2020
    Assignee: Spinal Singularity, Inc.
    Inventors: Derek Herrera, Alex Shen
  • Pulmonary-systemic shunt devices and related methods
    Patent number: 10675395
    Abstract: A method for treating a patient may include establishing an anastomosis between a pulmonary artery and an aorta; and pumping blood from the pulmonary artery to the aorta when the pulmonary artery has a pressure lower than or equal to a pressure of the aorta.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: June 9, 2020
    Assignees: Boston Scientific Scimed, Inc., Regents of the University of Minnesota
    Inventors: Umang Anand, Adam J. Black, Ahmed Selim, Steven D. Reinitz, Bradley F. Slaker, Andrew D. Bicek, Paul F. Chouinard
  • Bypass device for the transpyloric conducting of gastric content into or through the duodenum, and applicator for putting same in place
    Patent number: 10667936
    Abstract: The invention relates to a transpyloric device for accepting chyme from the stomach and conducting said chyme on in a bypass-like manner through a patient's duodenum; said device is held in place by balloon segments which sit on a preferably radially collapsible and self-erecting transpyloric conducting element; the filling level of the balloon segments, and thus the axial sealing force acting primarily on the shoulder surfaces of the pylorus or the surrounding area thereof, can be adjusted by the user, and the force applied to the stomach and duodenum structures adjoining the pylorus is reduced to a level that is permanently bearable for the organs even when the filling pressure of the segments rolling against each other is elevated. The invention also relates to an applicator for putting a bypass device of said type in place in the region of the transition from the stomach to the duodenum.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: June 2, 2020
    Assignee: Trans-Duodenal Concepts GmbH
    Inventor: Fred Göbel
  • Magnetic vascular access graft
    Patent number: 10667898
    Abstract: The invention relates to generally to a vascular access graft that includes a magnetic element disposed about a flow tube for guiding a blood flow between an arterial end adapted for arterial anastomosis to a portion of an artery, and a venous end adapted for venous anastomosis to a portion of a vein. The magnetic element may include a plurality of magnets disposed about the flow tube so that a magnetic field may be applied to blood flowing therein; the magnetic element may alternatively include a circuitry configured to generate a magnetic field applied to the flow tube.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: June 2, 2020
    Inventor: Henry Gonzalez
  • System and method for injection component preparation
    Patent number: 10660823
    Abstract: An assembly for mixing drug components includes a housing to at least partially hold a first drug component container and a second drug component container. The assembly also includes a transfer member having first and second ends to fluidly couple the respective first and second drug component containers. The assembly further includes a pressure member to fluidly couple the first drug component container to a pressure generation chamber. In addition, the assembly includes an energy storage member to generate pressure in the pressure generation chamber to transfer a fluid from the first drug component container into the second drug component container. Moreover, the assembly includes an exit member to fluidly couple the second drug component container to an exterior of the assembly.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: May 26, 2020
    Assignee: CREDENCE MEDSYSTEMS, INC.
    Inventors: Alan E. Shluzas, Stephen H. Diaz
  • Cardioplegic agent delivery system
    Patent number: 10646637
    Abstract: A cardioplegic agent delivery system comprises a syringe pump for providing cardioplegic agent into a carrier fluid of a perfusion system, a flow sensor for sensing a flow of the carrier fluid, and an interlock responsive to the flow sensor. The interlock prevents operation of the syringe pump in the absence of carrier fluid flow sensed by the flow sensor. This provides increased safety in a cardioplegic agent delivery system.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: May 12, 2020
    Assignee: Spectrum Medical Ltd.
    Inventor: Stephen Turner
  • Peristaltic pump comprising modular casing
    Patent number: 10639409
    Abstract: A peristaltic pump for an apparatus for extracorporeal blood treatment, especially for a dialysis machine, for delivering fluid in the apparatus is disclosed. The peristaltic pump includes a rotor driven to rotate about a rotor axis and a pump casing surrounding the rotor at least in part and including a supporting surface being configured to be curved around the rotor axis, wherein an elastically deformable fluid line is adapted to be positioned between the rotor and the supporting surface and is deformed between the rotor and the supporting surface while forming a cross-sectional constriction for fluid delivery by rotation of the rotor, the pump casing having a modular design and including a supporting surface module forming the supporting surface and a casing module adapted to be coupled to the former and surrounding the rotor at least in part.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: May 5, 2020
    Assignee: B. Braun Avitum AG
    Inventor: Oliver Schäfer
  • Shielding device useful for manipulating a radioactive solution
    Patent number: 10639420
    Abstract: The present disclosure relates to a device (1) for sampling and/or injection of a radioactive solution (S) in a vial (2), wherein the vial (2) comprises an opening closed by a puncturable closure member (3).
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: May 5, 2020
    Assignee: SIMPLIVIA HEALTHCARE LTD.
    Inventors: Julien Le Maitre, Pierre-Marie Lemer
  • Devices and methods for treating heart failure
    Patent number: 10632292
    Abstract: A device for implanting into an atrial septum of a patient. In some embodiments, the device has a core region to be disposed in an opening in the atrial septum; a distal retention region adapted to engage tissue on a left atrial side of the septal wall; a proximal retention region adapted to engage tissue on a right atrial side of the septal wall; and a retrieval region comprising a plurality of retrieval members, each retrieval member comprising a connector at a proximal end, the connector being adapted to connect to a delivery system. The device has a delivery configuration and a deployed configuration, the core region, distal retention region and proximal retention region each having a smaller diameter in the delivery configuration than in the deployed configuration, the retrieval member connectors being disposed proximal to and radially outward from the opening in the deployed configuration.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: April 28, 2020
    Assignee: Corvia Medical, Inc.
    Inventors: Stephen J. Forcucci, Matthew J. Finch, Christopher J. Magnin, Edward I. McNamara, Carol A. Devellian
  • Shunt device and a method for shunting cerebrospinal fluid
    Patent number: 10625060
    Abstract: A shunt device for shunting cerebrospinal fluid (CSF) from a CSF containing space to a sinus system cavity comprises a tubular inlet element, a flow restricting part, and a tubular outlet element having an outlet end with an outlet opening for insertion in the sinus system cavity, and a one-way valve preventing flow in a direction from the outlet opening to the inlet opening. The shunt device further comprises a distancer, said distancer being provided at the outlet end of the tubular outlet element.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: April 21, 2020
    Assignee: CSF-DYNAMICS A/S
    Inventor: Svend Erik Børgesen