Abstract: Systems, methods, and devices that relate to an automated auditing system of the network conditions are disclosed. In one example aspect, a network device in a core network for wireless communication include one or more processors that are configured to determine an expected network state based on predefined configuration information of one or more network resources, receive measurement results reported by one or more wireless devices via at least one radio access node, estimate an actual network state based on the measurement results reported by one or more wireless devices, and detect a discrepancy between the expected network state and the actual network state.

Abstract: Provided herein are polynucleic acids and expression vectors for the expression and secretion of angiotensin peptide fragments (e.g., angiotensin-(1-7)) in probiotic bacteria. Provided herein are also probiotic compositions that enable efficient, cost-effective and patient friendly oral therapeutics for treating diverse pathological conditions that involve the renin-angiotensin system (RAS), e.g., pulmonary hypertension, diabetes, diabetic complications, cardiovascular diseases, and ocular inflammatory and neurodegenerative diseases.

Abstract: There is provided an optical network device (30) comprising separate downstream and upstream signal paths (33, 34) disposed between a wavelength division multiplexing unit (16) and a signal splitting element (32, 44, 50), an optical to electrical signal converter (18) disposed in the downstream path and an electrical to optical signal converter (22) disposed in the upstream path, wherein the signal splitting element (32, 44, 50) is capable of splitting signals independent of signal frequency and is configured with an isolation of 30 to 50 dB thereby to substantially prevent leakage of downstream signals into upstream path (34). The signal splitting element is capable of splitting signals independent of signal frequency and may be a directional coupler, two-way signal splitter or hybrid coupler comprising at least two different types of coupler element.

Abstract: The present disclosure relates to a communication technique which combines a 5G communication system, for supporting a higher data transmission rate than 4G systems, with IoT technology, and a system for same. The present disclosure may be applied to intelligent services (for example, smart homes, smart buildings, smart cities, smart cars or connected cars, health care, digital education, retailers, security and safety-related services, or the like) on the basis of 5G communication technology and IoT-related technology. Disclosed is a method for providing subscription information about non-public networks to a terminal in a wireless communication system.

Abstract: Disclosed are a positioning method in a wireless communication system, and a device for supporting same.

Abstract: The string trimmer includes a connecting rod, a string trimmer head, and an operation part. The string trimmer head includes a trimmer line, a spool, a housing, and a streamlined protection structure. The spool is configured to wind the trimmer line and is capable of rotating about a first axis. The housing has an accommodating cavity for accommodating at least part of the spool and a threading hole for the trimmer line to extend to an outer side of the housing. The protection structure includes a head, a tail and a passage through which the trimmer line penetrates. The head is connected to the housing, the tail extends on the outer side of the housing, and the passage is configured to accommodate the trimmer line penetrating through the threading hole and expose the trimmer line out of the tail of the protection structure.

Abstract: Provided is Lactobacillus paracasei TCI727, deposited in the Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ) with a deposit number of DSM 33756. A method for improving calcium absorption of a subject in need thereof by using the Lactobacillus paracasei TCI727 or metabolites thereof is also provided. The method includes administering to the subject an effective amount of a composition comprising the Lactobacillus paracasei TCI727 or the metabolites thereof.

Abstract: An approach for blockchain transaction processing using generative cryptograms for bi-lateral and Multi-lateral transactions may be provided. The approach may include, the use of decentralization ledger storage, negating the need of repetitive storage while preserving the need for data redundancy. A generative cryptogram may provide verification of processed blocks and file handles or storage address schemes of the ledger storage. The approach creates a cryptogram which is added to transaction processing, post processing and commits to the ledger. In the approach, the cryptogram is the only version of storage pointer and is utilized in subsequent transaction processing without the need for extensive compute and latest cryptogram is all that would be needed for transaction processing.

Abstract: Thermostable Cas9 nucleases. The present invention relates to the field of genetic engineering and more particularly to nucleic acid editing and genome modification. The present invention provides an isolated Cas protein or polypeptide fragment thereof having an amino acid sequence of SEQ ID NO: 1 or a sequence of at least 77% identity therewith. The Cas protein or polypeptide is capable of binding, cleaving, marking or modifying a double stranded target polynucleotide at a temperature in the range 20° C. and 100° C. inclusive. The invention further provides isolated nucleic acid molecules encoding the Cas9 nucleases, expression vectors and host cells. The invention also provides PAM sequences recognized by the Cas protein or polypeptide, The Cas9 nucleases disclosed herein provide novel tools for genetic engineering in general, in particular at elevated temperatures and are of particular value in the genetic manipulation of thermophilic organisms; particularly microorganisms.

Abstract: Provided is an improved estimation and identification device that estimates the position of a plurality of identification targets and identifies the plurality of identification targets.

Abstract: In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.

Abstract: A fault detection apparatus includes: a transmitter that transmits a first optical signal through an optical transmission line; a receiver that receives, in response to the transmission of the first optical signal, a second optical signal from the line, and measures the reception level of the second optical signal; and a control unit that specifies a section where the second optical signal corresponding to the first optical signal was generated, calculates an optical level corresponding to a loss in said section on the basis of the reception level, determines that a first fault has occurred in the section when the optical level in the section has changed from a first reference level by a first threshold or more, sets a second reference level and a second threshold after occurrence of the first fault, and determines occurrence of a second fault.

Abstract: An optical transmission apparatus (1_1) according to the present invention includes a first transmission unit (11_1) that transmits a first optical transmission signal (21_1), a second transmission unit (11_2) that transmits a second optical transmission signal (21_2), and an output unit that outputs, when the first optical transmission signal (21_1) and the second optical transmission signal (21_2) share a set of information, both the first optical transmission signal (21_1) and the second optical transmission signal (21_2) to a first path (26_1) and outputs, when the first optical transmission signal (21_1) and the second optical transmission signal (21_2) do not share the set of information, one of the first optical transmission signal (21_1) and the second optical transmission signal (21_2) to a second path (26_2).

Abstract: In an example embodiment, an optical communication system includes an implantable optical transmitter and an external optical receiver. The transmitter includes a housing having one or more drivers, plural light emitting sources, and an optical element arranged therein. Each driver converts a digital data signal into modulation signals to drive the sources. Each source generates a light beam in response to a corresponding modulation signal, each light beam contributing to form a single optical signal. The optical element directs the light beams to exit the housing such that a peak position of light intensity of each light beam is separated from a corresponding peak position of light intensity of an adjacent light beam by at least a first distance and less than a second distance. The optical receiver includes at least one photodiode that detects light generated by the sources and generates a reconstructed data signal.

Abstract: A coupling mechanism for connecting a replaceable shaving cartridge of a shaving device to a handle of the shaving device includes a first connector, a second connector, and a locking member. The first connector of the replaceable shaving cartridge is adapted to move along an axial direction. The second connector of the handle is adapted to move along a substantially arc-shaped path with respect to the handle when at least one connector of the first connector and the second connector is pushed against the other connector. The second connector is adapted to mechanically engage with the first connector in the course of its motion so as to reach an engaged position with the first connector. The locking member of the handle is adapted to lock the second connector when the latter is in the engaged position with the first connector.

Abstract: Described implementations obtain credential information including an encrypted digital identity (ID). The encrypted digital ID may include a public component of a credential and identity data. Furthermore, the credential information may include cryptographically obfuscated data based on the identity data and a private component of the credential. A proof is obtained that includes proof data. The proof data may confirm that the credential information was correctly generated. Verification of the proof data, and confirmation that the cryptographically obfuscated data is not associated in a collection of cryptographically obfuscated data, cause a computer-implemented service to issue a pseudonym. The pseudonym is usable to generate a relationship associated with a computer-implemented service.

Abstract: Described herein is the use sodium (E)-2-(4-((3-(4-fluorophenyl)-3-(4-(3-morpholinoprop-1-yn-1-yl)phenyl)allyl)oxy)-2-methylphenoxy)acetate in the preparation of pharmaceutical compositions for the treatment of diseases or conditions that would benefit by administration with a PPAR? agonist compound.

Abstract: Compositions and methods for binding to a target sequence of interest are provided. The compositions find use in cleaving or modifying a target sequence of interest, visualization of a target sequence of interest, and modifying the expression of a sequence of interest. Compositions comprise RNA-guided nuclease polypeptides, CRISPR RNAs, trans-activating CRISPR RNAs, guide RNAs, and nucleic acid molecules encoding the same. Vectors and host cells comprising the nucleic acid molecules are also provided. Further provided are CRISPR systems for binding a target sequence of interest, wherein the CRISPR system comprises an RNA-guided nuclease polypeptide and one or more guide RNAs.

Abstract: A method for protecting sensitive data from being exposed in graph embedding vectors. In some embodiments, a method may include generating first graph embedding vectors from an original graph and generating a proxy graph from the first graph embedding vectors. The proxy graph may include a plurality of proxy nodes and proxy edges connecting the proxy nodes. The proxy nodes may include one or more attributes of the original nodes that are included in the first graph embedding vectors. Second graph embedding vectors may then be generated by encoding the proxy graph and a reconstructed graph may be generated from the second graph embedding vectors. Finally, the reconstructed graph may be compared to the original graph and if a threshold level of similarity is met, a security action may be performed to protect sensitive data from being exposed.

Abstract: Embodiments include a bar for a chain saw that is equipped with one or more oil channels that run along the length of the bar. Each oil channel receives oil at a first end, which exits the oil channel at an oil exit aperture at a second end of the channel. The oil exit aperture of one of the channels is positioned along the side of a bar groove, through which runs the saw chain, proximate to the cutting area of the bar to lubricate the saw chain just prior to the cutting area. A second channel may have an oil exit aperture proximate to the nose of the bar, to lubricate a sprocket wheel in the nose of the bar.