Abstract: An anchor inserter provides for inserting an anchor into a hole in body tissue. The anchor inserter has an elongated shaft with a first axis and a distal end and an insertion tip. The insertion tip has a driving tip extending distally from the distal end of the shaft to terminate in an anchor engaging interface. A resiliency between the anchor engaging interface and the shaft allows bending away from the first axis. An abutment member extends distally from the shaft and has a distally facing abutment surface adjacent the driving tip which abuts the anchor and allows an axial force to be transmitted thereto. Preferably, the abutment member comprises a collar extending from the shaft and coaxially receiving the driving tip.

Abstract: A subintimal recanalization catheter system for recanalizing a blood vessel. The system includes a support catheter and a balloon catheter configured to extend through the support catheter. The support catheter includes a tubular portion and an extension segment extending distal of the distal opening of the tubular portion. The balloon catheter, having a balloon secured to a distal portion thereof, is positionable through the tubular portion of the support catheter to position the balloon alongside the extension segment. The system is configured to be advanced into a subintimal space between a first tissue layer and a second tissue layer of a blood vessel wall where the balloon may be inflated against the extension segment to cause a distal portion of the catheter shaft of the balloon catheter to deflect toward the vessel lumen within the subintimal space to facilitate reentry into the vessel lumen.

Abstract: A tunneling tool for implanting a medical device into body tissue is described. The tunneling tool comprises a first leg and a second leg. An intermediate portion of the second leg is shaped to nest a medical device therein. A hub connects the first and second distal leg ends together. A sheath providing a lumen extends from the hub to an open end distal of the first and second legs. The first and second legs are manipulatable to separate the hub and the sheath into two portions, a first split portion connected to the first leg and a second split portion connected to the second leg. When a medical device is nested in the tunneling tool, breaking the tunneling tool apart enables the first and second split portions to be removed from body tissue, leaving the implanted medical device behind.

Abstract: An endoscopic tissue apposition device that includes a vacuum chamber configured to securely hold a portion of tissue therein, the vacuum chamber being defined by a proximal wall and a distal wall opposite to the proximal wall. Working and vacuum channels are provided in communication with the vacuum chamber. A portion of tissue may be held in the vacuum chamber when vacuum is applied in the vacuum chamber through the vacuum channel. A carrier needle is disposed on a proximal side of the vacuum chamber and is longitudinally advanceable into and across the vacuum chamber, while a punch needle is disposed on a distal side of the vacuum chamber and is configured to receive the carrier needle therein. A hold and release mechanism holds and releases the punch needle to facilitate joining portions of tissue together.

Abstract: An assembly including an obstruction device including a proximal obstruction balloon and a distal obstruction balloon mounted on a shaft, the balloons being inflatable via an inflation lumen, and a delivery system that includes an insertion tool and an injection site assembly assembled with one of the balloons, the insertion tool including a connector which is connectable to the injection site assembly and which permits passing tools and injection fluid therethrough.

Abstract: A method and article of manufacture for reducing facial wrinkles, namely sleep lines, formed during sleep. The article is formed having an inner and outer surface wherein each surface has higher or lower friction coefficients relative to one another. The higher friction coefficient inner surface holds the article in place against the skin and the lower friction coefficient outer surface facilitates movement of the face relative to the bedding during sleep.

Abstract: An apparatus for application of surgical clips to body tissue is provided and includes a handle assembly; a shaft assembly including a housing extending distally from the handle assembly and defining a longitudinal axis; a plurality of surgical clips disposed within the shaft assembly; a jaw mounted adjacent a distal end portion of the shaft assembly, the jaw being movable between an open spaced-apart condition and a closed approximated condition; and a pusher bar reciprocally disposed within the housing of the shaft assembly and being detachably connectable to the housing of the shaft assembly, the pusher bar being configured to load a distal-most surgical clip into the jaws during distal movement and remain connected to the housing of the shaft assembly and in a distally advanced position during an approximation of the jaws.

Abstract: Embodiments of systems and methods for a teething device for an article of clothing configured to cover a foot with toes. The teething device includes a teether that is coupled to an outer surface of the article of clothing and extends in a direction parallel to the toes.

Abstract: A medical device includes (a) a capsule including a lumen extending therethrough, a proximal end of the capsule including at least one window extending therethrough; (b) a bushing including a channel extending therethrough, a distal end including at least one arm extending distally therefrom such that a corresponding one of the arms is releasably engagable with a corresponding one of the windows; and (c) a core member including a locking portion and at least one engaging element. The locking portion is sized and shaped to be received within the channel of the bushing to apply a pressure to the arm such that the arm engages the windows. The engaging element extends laterally outward from a portion of the core member such that the engaging element engages a corresponding one of the arms to deform the arms radially inward and out of engagement with the windows.