Abstract: A vestibular stimulation array is disclosed having one or more separate electrode arrays each operatively adapted for implantation in a semicircular canal of the vestibular system, wherein each separate electrode array is dimensioned and constructed so that residual vestibular function is preserved. In particular, the electrode arrays are dimensioned such that the membranous labyrinth is not substantially compressed. Furthermore, the electrode array has a stop portion to limit insertion of the electrode array into the semi-circular canal and is still enough to avoid damage to the anatomical structures.

Abstract: A method of controlling an eye surgical laser is disclosed for the separation of a volume body with predefined posterior and anterior interfaces from a human/animal cornea. The method including controlling the laser with a control device, the laser being configured to emit pulsed laser pulses in a predefined pattern into the cornea. The posterior and anterior interfaces of the volume body are defined by the predefined pattern and are generated by an interaction of the individual laser pulses with the cornea through photodisruption. The control device controls the laser beam such that both interfaces are generated via a continuous, uninterrupted sequence of laser pulses. A treatment device is disclosed with at least one eye surgical laser for the separation of a predefined corneal volume with predefined interfaces of a human/animal eye by photodisruption and with at least one control device for the laser(s).

Abstract: An iontophoretic patch for transdermal delivery of biologically active agents includes at least two electrodes in contact with at least two hydrogel reservoirs. At least one of the hydrogel reservoirs carries at least one active agent and, in use of the iontophoretic patch, is disposed on a user's skin and delivers at least one active agent into the skin. The patch includes a control unit to generate a stimulation pattern having stimulation parameters delivered to stimuli locations on the skin. A stimulation unit generates a time sequence of pulses from the stimulation parameters generated by the control unit. The patch further includes a demultiplexing unit configured to perform independent spatio-temporal distribution of the electrical pulses in the time sequence of pulses to at least one electrode; at least one optical sensing system, for continuously measuring an amount of the active agent in the hydrogel reservoir; and a feedback unit.

Abstract: A catheter is disclosed for performing ultraviolet light therapy in a pulmonary system of a patient, which includes a catheter body having opposed proximal and distal end portions, a handle assembly operatively associated with the proximal end portion of the catheter body, an illumination assembly operatively associated with the distal end portion of the catheter body and including an LED light source for generating UVC radiation, wherein the illumination assembly includes a coupler connecting the LED light source with the distal end portion of the catheter body, and an elongated braided sleeve disposed within the catheter body, wherein the coupler is adapted to transfer heat from the illumination assembly to the braided sleeve, such that the braided sleeve serves as a heat sink for the illumination assembly.

Abstract: An example of a system for programming neurostimulation according to a stimulation configuration may include stimulation configuration circuitry, volume definition circuitry, stimulation effect circuitry, and recording circuitry. The stimulation configuration circuitry may be configured to determine the stimulation configuration. The volume definition circuitry may be configured to determine stimulation field model(s) (SFM(s)) each representing a volume of tissue activated by the neurostimulation. The stimulation effect circuitry may be configured to determine a stimulation effect type for each tagging point specified for the SFM(s) and to tag the SFM(s) at each tagging point with the stimulation effect type determined for that tagging point. The stimulation effect type for each tagging point is a type of stimulation resulting from the neurostimulation as measured at that tagging point.

Abstract: This application is generally related to systems and methods for providing a medical therapy to a patient by tracking patient activity and adjusting medical therapy based on occurrence of different types of activities performed by the patient including user indicated activities inputted from an icon driven user interface of an external patient controller device.

Abstract: An object of the present invention is to provide a chair-type phototherapy device that enables a patient to perform light irradiation accurately targeted at a treatment site in a seated position on a chair and consequently achieves effective phototherapy even when the treatment site is in the back region that the patient is unable to see, for example, as in light irradiation for dysuria patients and patients with pain, and the patient performs light irradiation by himself/herself at home. The present invention provides a chair-type phototherapy device having a seat on which a patient is seated. The chair-type phototherapy device includes a radiation module configured to emit radiation light toward a living body, a drive module positioned behind the patient for moving the radiation module, and a fixing module fixing the drive module to the seat.

Abstract: A system and method for improving heart contractions during a heart function cycle (heartbeat) of a patient requires detecting a local electrical event (depolarization) during the cycle. This local electrical event is then used to trigger a stimulation interval ?t at a time t0. Importantly, the stimulation interval ?t is set to end at a time t1 during the absolute refractory period of the heart function cycle. At the time t1, a stimulator is triggered to stimulate a local sympathetic nerve on the epicardial surface of the heart. With this stimulation the sympathetic nerve secretes norepinephrine to improve a subsequent contraction of the heart.

Abstract: Disclosed are various examples and embodiments of systems, devices, components and methods configured to treat mood disorders in a patient using a compact implantable neurostimulator and corresponding lead(s) that are shaped, sized and configured to be implanted beneath a patient's skin in the head or neck, and to stimulate one or more target cranial nerves. The one or more medical electrical leads comprising electrode(s) are positioned adjacent to, in contact with, or in operative positional relationship to, the one or more target cranial nerves of the patient. In some embodiments, electrical stimulation is provided to the one or more target cranial nerve(s) of the patient for periods of time ranging between 30 and 60 minutes, once or twice per day. In some embodiments, power is provided to the implantable neurostimulator transcutaneously by inductive, wireless, RF, acoustic, microwave, or other suitable non-invasive means.

Abstract: The present invention uses one or more radiation-emitting devices in combination with a topical radiation block to ablate the skin and remove topographic variations in the skin surface. The energy pathway may be guided by a computer. The device might also include a treatment plate or window to be placed against the skin in order to flatten the skin surface during treatment. The purpose of the topical radiation block is to manage the areas to which the radiation is applied to the skin by allowing the radiation to reach some portions of the skin, while limiting or preventing the radiation from reaching other portions of the skin. In the case of atrophic scarring, for example, the block may be deposited selectively into the atrophic indentations, such that the block limits or prevents the radiation from reaching (and thereby ablating) the indentations, but allows the radiation to reach (and thereby ablate) the surrounding skin tissue.

Abstract: Disclosed is a method of enhancing exposure therapy including providing an exposure therapy to a patient and stimulating the patient's vagus nerve at the same time as the exposure therapy. Also disclosed is a post-traumatic stress disorder therapy method including providing an exposure event to a patient and stimulating the patient's vagus nerve during the exposure event. Also disclosed is a phobia disorder therapy method including providing an extinction event to a patient and stimulating the patient's vagus nerve during the exposure event. Also disclosed is an obsessive compulsive disorder therapy method including providing a therapy event to a patient and stimulating the patient's vagus nerve during the therapy event. Also disclosed is an addiction disorder therapy method including providing a therapy event to a patient and stimulating the patient's vagus nerve during the therapy event.

Abstract: A physiological sensor device and system, and a correction method are provided. The physiological sensor device includes a physiological signal sensor, a first compensation sensor, and a signal processing device. The physiological signal sensor is attached to an object to be detected to sense a physiological signal value. The first compensation sensor is disposed on the physiological signal sensor. The signal processing device is coupled to the physiological signal sensor and the first compensation sensor. The signal processing device obtains through the first compensation sensor a failure region of the physiological signal sensor partially detached from the object to be detected and obtains a first failure compensation value according to the failure region, so as to compensate the physiological signal value sensed by the physiological signal sensor.

Abstract: A Wearable Cardioverter Defibrillator (WCD) system comprises an electrode assembly with a permeable ECG electrode and a moisture barrier. In some embodiments, the moisture barrier is configured to reduce drying out of the permeable ECG electrode to improve performance of the WCD system. In a further enhancement, some embodiments of the electrode assembly also include a pillow structure positioned on a non-skin-contacting surface of the electrode assembly to comfortably reduce movement artifact or noise in the received ECG signal.

Abstract: This document discusses, among other things, systems and methods for managing pain of a subject. A system includes one or more physiological sensors configured to sense a physiological signal indicative of patient brain activity. The physiological signals may include an electroencephalography signal, a magnetoencephalography signal, or a brain-evoked potential. The system may extract from the brain activity signal one or more signal metrics indicative of strength or pattern of brain electromagnetic activity associated with pain, and generate a pain score using the one or more signal metrics. The pain score can be output to a patient or a process. The system may select an electrode configuration for pain-relief electrostimulation based on the pain score, and deliver a closed-loop pain therapy according to the selected electrode configuration.

Abstract: Disclosed is an iontophoresis-based patch type skin care device for allowing a functional substance for skin care to be effectively absorbed into a user's skin by causing iontophoresis on the user's skin through a conductive patch. The iontophoresis-based patch type skin care device for allowing the functional substance for the skin care to be absorbed into the user's skin by the iontophoresis includes a skin care device body that generates power to cause the iontophoresis. The skin care device body includes a power circuit that is provided in an interior space of a body and that includes a power unit that generates the power for the iontophoresis and one or more electrodes to which the power is applied, and a bridge that is provided so as to be combinable with the body and that receives the power through the one or more electrodes.

Abstract: The invention relates to a system for laser photocoagulation of the retina, comprising: a photocoagulation laser (1); an optical path (5) connecting the upstream photocoagulation laser (1) to a downstream laser outlet opening (6) intended to be positioned in front of the retina; an adaptive optical element (9) positioned in the optical path and configured to modify the wavefront of the laser beam being propagated in the optical path, in order to compensate for aberrations of the eye that occur as far as the retina; a position control loop (10) controlling a first actuator (14) positioned in the optical path downstream of the adaptive optical element in order to control the position of the laser outlet opening relative to the retina to be treated; and at least one imaging device (8) configured to obtain an image of the retina diverted from the optical path.

Abstract: A light treatment system includes: a probe configured to be inserted into a body cavity, the probe including an optical fiber configured to propagate light, and a light emitter that is provided at a distal end of the optical fiber, the emitter being configured to emit the light; a balloon catheter into which the probe is inserted, the balloon catheter including a distal end portion that is to be inserted into the body cavity and that is to be dilated by being supplied with a liquid including air bubbles; and an air bubble generator configured to generate the air bubbles to be included in the liquid and change a property of the air bubbles.

Abstract: Improved hydrogel configurations for use with a TTField-generating system is disclosed. Also disclosed are kits containing the improved hydrogel configurations and methods of producing and using the improved hydrogel configurations.

Abstract: In order to help reduce the effects of motion sickness, there is provided a method for reducing motion sickness in a subject which comprises acquiring a sequence of video images, extracting measurements of a heart-rate of the subject over a first period of time from the sequence of video images using photoplethysmography (PPG), calculating at least one trend in the measurements, determining a presence of motion sickness when the at least one trend is positive over a first time window, the first time window being included in the first period of time, and generating an event arranged to generate a corrective action. It is often possible to detect the onset of motion sickness before the subject actually feels the symptoms. Indeed, by the time the symptoms appear, corrective action is much less effective. Therefore, by detecting the onset early and alerting the subject so that they can react, it is possible to avoid the attack of motion sickness or, at least, reduce significantly its effects.

Abstract: A neuromodulation system includes a conductive element, a magnetic field generator, a power module and a computer processor. The conductive element located internal a patient's body. At least a portion of the conductive element is positioned adjacent to a target tissue. The magnetic field generator is positioned external to the patient's body. The magnetic field generator generates a time varying magnetic field for inducing stimulation of the target tissue in combination with the conductive element to produce stimulation that is larger than that which would occur in the absence of the conductive element. The power module supplies power to the magnetic field generator. The computer processor controls the time varying magnetic field provided by the magnetic field generator according to at least one set of stimulation parameters.