Patents Examined by Manuel A Mendez
  • Patent number: 11904142
    Abstract: A needleless injector is provided. The needleless injector includes a loading lever having a working arm part having a lever shaft, a towing member inserted inside the cylinder housing, a link having one end portion pin-coupled to the working arm part and the other end portion pin-coupled to the towing member, an inner cylinder inserted inside the cylinder housing, a spring inserted into the inner cylinder, an actuating head inserted into the inner cylinder in front of the spring and having a catching protrusion configured to be inserted into the slit, and a trigger means having a stopper head part configured to be able to be inserted into the slit of the inner cylinder and detached from the slit. Accordingly, the needleless injector can achieve a reduction in size and thickness by having a simple structure even with a lever for reloading integrally formed therein.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: February 20, 2024
    Inventor: Min Su Cho
  • Patent number: 11904138
    Abstract: Disclosed herein are techniques related to glucose level management without carbohydrate counting. The techniques may involve obtaining contextual information for a meal, predicting amounts of glucose to be absorbed into a bloodstream of the patient over a duration of time due to consumption of the meal based on the contextual information for the meal, determining one or more amounts of insulin to counteract effects of the predicted amounts of glucose, and affecting insulin therapy based on outputting information indicative of the determined one or more amounts of insulin.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: February 20, 2024
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Boyi Jiang, Yuxiang Zhong, Pratik J. Agrawal, Ali Dianaty
  • Patent number: 11904140
    Abstract: The exemplary embodiments provide medicament delivery devices that use cost functions in their control systems to determine medicament dosages. The cost function may have a medicament cost component and a performance cost component. The exemplary embodiments may use cost functions having medicament cost components that scale asymmetrically for different ranges of inputs (i.e., different candidate medicament dosages). The variance in scaling for different input ranges provides added flexibility to tailor the medicament cost component to the user and thus provide better management of medicament delivery to the user and better conformance to a performance target. The exemplary embodiments may use a cost function that has a medicament cost component (such as an insulin cost component) of zero for candidate dosages for a range of candidate dosages (e.g., below a reference dosage).
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: February 20, 2024
    Assignee: INSULET CORPORATION
    Inventors: Joon Bok Lee, Yibin Zheng, Jason O'Connor, Trang Ly
  • Patent number: 11890442
    Abstract: Systems and methods for detecting an implanted medical device, such as a vascular access port. The implanted medical device may include at least one passive RFID tag that has disposed thereon information about the implanted medical device. The at least one passive RFID tag is designed to be interrogated by a detector associated with an external device, such as an infusion set with an access needle. The interrogating signal induces a return signal from the at least one passive RFID tags. The strength of the return signal may be dependent on the distance and orientation of the tag relative to the detector. The system may be designed to interpret different signal strengths from different RFID tags to guide the needle to a correct insertion position, thereby accessing a port that cannot be readily detected visually or by palpation.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: February 6, 2024
    Assignee: Bard Peripheral Vascular, Inc.
    Inventor: Murtaza Y. Amin
  • Patent number: 11878136
    Abstract: A system, apparatus and method for a tightly sealed, low moisture vapor transmission, low relative humidity headspace atmosphere aseptic vaccine delivery with low particulate generation. The system can include a housing, desiccant and a biasing member designed to quickly and efficiently deliver medicament to a patient.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: January 23, 2024
    Assignee: CSP TECHNOLOGIES, INC.
    Inventors: Jean-Pierre Giraud, Franklin Lee Lucas, Jr., Bruce Rabinne
  • Patent number: 11872034
    Abstract: Machine learning in an artificial pancreas is described. An artificial pancreas system may include a wearable glucose monitoring device, an insulin delivery system, and a computing device. Broadly speaking, the wearable glucose monitoring device provides glucose measurements of a person continuously. The artificial pancreas algorithm, which may be implemented at the computing device, determines doses of insulin to deliver to the person based on a variety of aspects for the purpose of maintaining the person's glucose within a target range, as indicated by those glucose measurements. The insulin delivery system then delivers those determined doses to the person. As the artificial pancreas algorithm determines insulin doses for the person over time and effectiveness of the insulin doses to maintain the person's glucose level in the target range is observed, an underlying model of the artificial pancreas algorithm may be updated to better determine insulin doses.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: January 16, 2024
    Assignee: DEXCOM, INC.
    Inventors: Derek James Escobar, Naresh C. Bhavaraju, Gary A. Morris, Jorge Valdes
  • Patent number: 11857672
    Abstract: The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.
    Type: Grant
    Filed: January 26, 2022
    Date of Patent: January 2, 2024
    Assignee: NanoVault Medical, LLC
    Inventors: Willard W. Hennemann, Bryan L. Steelman, Thomas J. Webster, Janet E. Davis
  • Patent number: 11857764
    Abstract: Missed meal bolus reminders or alerts require a user to access the user's pump and/or remote control to clear the reminder/alert even when the user skipped a meal such that no meal bolus was needed. CGM data can be leveraged such that the missed meal bolus alert is only triggered when glucose levels rise in response to consuming the meal within the programmed time window. Therefore, the alert is only provided when a meal is actually consumed and no bolus has been delivered. This further allows the user to be alerted sooner, i.e., as soon as glucose levels rise a predetermined amount or passed a predetermined threshold indicating consumption of a meal as opposed to only at the end of the programmed window.
    Type: Grant
    Filed: September 8, 2021
    Date of Patent: January 2, 2024
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Paul Harris
  • Patent number: 11857670
    Abstract: The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.
    Type: Grant
    Filed: August 5, 2020
    Date of Patent: January 2, 2024
    Assignee: NanoVault Medical, LLC
    Inventors: Willard W. Hennemann, Bryan L. Steelman, Thomas J. Webster, Janet E. Davis
  • Patent number: 11857673
    Abstract: A material includes a metallic, nanoporous structure having a plurality of nanopores having a porosity that allows passage of insulin but not IgG. The metallic nanoporous structure includes titanium, 316L stainless steel and may have a textured nano-sericeous surface. A nanoporous bicontinuous structure can be integrated with nanopores.
    Type: Grant
    Filed: October 24, 2022
    Date of Patent: January 2, 2024
    Assignee: NanoVault Medical, LLC
    Inventors: Willard W. Hennemann, Bryan L. Steelman, Thomas J. Webster, Janet E. Davis
  • Patent number: 11850399
    Abstract: This invention relates to a feedback predictive controller, systems comprising and methods employing the same. Preferably the feedback predictive controller and/or systems comprising the feedback predictive controller are part of an automatic insulin delivery system. The methods described herein can be used to control blood glucose concentration in a patient with diabetes. Preferably, the insulin delivery system is an artificial pancreas.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: December 26, 2023
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Derrick K. Rollins, Yong Mei
  • Patent number: 11850397
    Abstract: A medical device is configured to monitor, using one or more sensors, an environmental condition of a physical environment proximate to a medical device, and to determine when a value representative of the environmental condition exceeds a threshold for safe operation of the medical device with regard to care of a patient. Responsive to the value exceeding the threshold, an operation mode of the medical device is automatically switched from a first mode currently programmed for the care of the patient to a second mode, the second mode using different parameters than the first mode to control the medical device.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: December 26, 2023
    Assignee: CareFusion 303, Inc.
    Inventors: Jay Jyotindra Dave, Igor Nesterenko
  • Patent number: 11844930
    Abstract: A user-mountable electronic device includes a housing, an accelerometer located within the housing, and at least one processor located within the housing. The accelerometer measures acceleration of the user-mountable electronic device and is configured to generate an output in response to detecting acceleration of the user-mountable electronic device that is greater than a minimum acceleration threshold. The at least one processor controls operation of the user-mountable electronic device. The at least one processor is configured to receive the output generated by the accelerometer and, in response thereto, to transition from a dormant or standby state of the user-mountable electronic device to an active state of the user-mountable electronic device.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: December 19, 2023
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Sarnath Chattaraj, Hsi Fusselman, Davy Tong
  • Patent number: 11839745
    Abstract: An insulin device configured to control insulin dispensing based on insulin sensitivity. The insulin device includes a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data; a sensor configured to generate a blood glucose level measurement. The sensor is calibrated as a function of the psychological stress level data and the BMI data and the processor is configured to monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and identify a time when the BMI data counteracts a detected change in the blood glucose level measurement. The insulin device also includes an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data.
    Type: Grant
    Filed: July 13, 2021
    Date of Patent: December 12, 2023
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Stephen D. Patek, Basak Ozaslan, Linda Gonder-Frederick
  • Patent number: 11833042
    Abstract: This document provides devices and methods for the treatment of heart conditions such as valvular stenosis. For example, this document provides devices and methods by which a guide catheter can align itself with a blood flow stream to thereby help direct a guidewire or other elongate device transmitted from the guide catheter through an orifice of a heart valve.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: December 5, 2023
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Gurpreet S. Sandhu, Daniel B. Spoon, Brandon J. Tefft
  • Patent number: 11832941
    Abstract: Disclosed is a method for fabricating a wearable hydrogel glucose sensor, belonging to the technical field of biomedical sensing, including using polyacrylamide hydrogel as a basic material, preparing a hydrogel film by adding with phenylboronic acid group capable of recognizing glucose molecules, and carrying out grating writing on the hydrogel film in a femtosecond laser direct writing mode to obtain the wearable hydrogel glucose sensor. The hydrogel film combines with glucose and expands linearly, which makes the grating period and effective refractive index change. The quantitative measurement of glucose is realized by detecting the spatial position of diffraction band and the change of diffraction power intensity.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: December 5, 2023
    Assignee: JOINT SHANTOU INTERNATIONAL EYE CENTER OF SHANTOU UNIVERSITY AND THE CHINESE UNIVERSITY OF HONG KONG
    Inventors: Mingzhi Zhang, Hang Qu, Xuehao Hu, Xin Wen, Qingping Liu
  • Patent number: 11826557
    Abstract: An intravenous delivery system may have a liquid source containing a liquid, tubing, and an anti-run-dry membrane positioned such that the liquid, flowing form the liquid source to the tubing, passes through the anti-run-dry membrane. The anti-run-dry membrane may have a plurality of pores through which the liquid flows, and may be formed of a hydrophilic material that resists passage of air through the pores. The intravenous delivery system may further have a bubble point raising component that raises the bubble point of the anti-run-dry membrane. The bubble point raising component may, in some embodiments, be a high surface energy coating or additive.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: November 28, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Shaun Staley, Weston O. Whitaker, Jon Larsen
  • Patent number: 11826548
    Abstract: A system includes one or more processors and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of receiving, via a user interface, confirmation input that indicates user acceptance of a blood glucose (BG) measurement generated by a BG meter device, in response to receiving the confirmation input, using the BG measurement for performing both glucose sensor calibration and bolus calculation, and causing delivery of a bolus based on outputting a delivery command in accordance with the bolus calculation.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: November 28, 2023
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Louis J. Lintereur, Alexander S. Campbell, Taly G. Engel, David Dunleavy, Benyamin Grosman, Anirban Roy
  • Patent number: 11819659
    Abstract: A pump for infusing fluid, the pump including a pumping mechanism, a fluid delivery device, a plurality of electric field sensors, and a measurement component. The plurality of electric field sensors is configured to estimate either an electric field that is associated with a patient, or an electric field that is associated with a fluid path of the pump, or both. The measurement component is configured to receive the electric field estimates from each of the electric field sensors and further configured to measure the difference between the electric field estimates.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: November 21, 2023
    Assignee: DEKA Products Limited Partnership
    Inventors: David Blumberg, Jr., Michael F. Bellino
  • Patent number: 11806137
    Abstract: Disclosed herein are techniques related to automatic real-time meal detection. In some embodiments, the techniques involve obtaining a plurality of glucose concentration values and a plurality of plasma insulin concentration estimations, each glucose concentration value corresponding with a respective plasma insulin concentration estimation; generating an output based on applying a meal detection model to the plurality of glucose concentration values and the plurality of plasma insulin concentration estimations; and determining, based on the output, that a glucose concentration value of the plurality of glucose concentration values corresponds to an ongoing glycemic response to a meal.
    Type: Grant
    Filed: May 9, 2023
    Date of Patent: November 7, 2023
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Anirban Roy, Benyamin Grosman, Neha J. Parikh