Patents Examined by Manuel A Mendez
  • Patent number: 10814076
    Abstract: A method of increasing eustachian tube patency in human patients is disclosed wherein a eustachian tube targeting nasal administration device is utilized to deliver a surfactant/propellant mixture to the nasopharyngeal stoma of the auditory tube. The targeting capability of the administration device obviates the need for a spreading agent that would otherwise be required to enable at least a portion of surfactant to reach the eustachian tube orifice. More specifically, the non-targeting, indiscriminate delivery provided by nasal administration devices of the past required surfactant to spread over non-targeted tissue it was inadvertently applied to in order to reach the eustachian tube stoma. In addition, a method for treatment of otitis media is disclosed utilizing, in some preferred embodiments, a therapeutically active agent.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: October 27, 2020
    Inventors: Alex Nyirucz, Richard Lee Strauss, Alan Joseph Mautone
  • Patent number: 10814075
    Abstract: The invention relates to a plug for placing on a connection element (1) of a medical syringe, which is connectable to the connection element (1), the plug (2) comprising a through-duct (3) and being formed free of further connectivity or connection elements.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: October 27, 2020
    Assignee: Gerresheimer Regensburg GmbH
    Inventor: Andreas Fraas
  • Patent number: 10814108
    Abstract: Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: October 27, 2020
    Assignee: Intersect ENT, Inc.
    Inventors: Richard E. Kaufman, John Joseph Stankus, James Su
  • Patent number: 10814107
    Abstract: Vascular access system embodiments can be configured to remove gas and a piercing member from a catheter assembly. In some embodiments, vascular access systems can remove gas and at least a portion of a piercing member concurrently or simultaneously. In some embodiments, vascular access systems can remove gas before removing at least a portion of a piercing member. In several embodiments, a vascular access system can include a first barrel configured to remove gas and a second barrel configured to retract a piercing member.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: October 27, 2020
    Assignee: ICU Medical, Inc.
    Inventors: Bhupinder Chhikara, Srinath Lingutla, Brandon Eads
  • Patent number: 10814122
    Abstract: A flow control device (40) for controlling the flow of a pressurized fluent substance is disclosed. The device (40) includes a housing (44, 48, 52) having an inlet portion (44) for receiving the fluent substance, an outlet portion (48) for discharging the fluent substance, and a platform (52). The device (40) further has a valve (56) located within the housing (44, 48, 52). The valve (56) is located between the platform (52) and the outlet portion (48). The valve (56) has a flexible, resilient valve head portion (160) that has confronting, openable portions (212, 216) movable from a closed configuration to an open configuration when the valve head portion (160) is subjected to a pressure differential acting across the valve head portion (160).
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: October 27, 2020
    Assignee: AptarGroup, Inc.
    Inventors: John Miller Hess, III, Andrew Smith, Robert LaBean, Gregory Olechowski, Mark Honard
  • Patent number: 10806908
    Abstract: A balloon catheter for treating elongate diseased vessels with a variable diameter, comprising a pre-stretched balloon and a catheter shaft, which forms a wire lumen embodied to guide a guide wire and forms a liquid lumen by which a liquid can be fed to the balloon. The balloon is fastened to a first catheter shaft element at a first, proximal fastening site and fastened to a second catheter shaft element at a second, distal fastening site, wherein the second fastening site is movable along a longitudinal axis of the catheter shaft in relation to the first fastening site. The balloon surrounds a section of the catheter shaft which extends between the first and second fastening sites. Here, the section of the catheter shaft surrounded by the balloon encloses different regions of the catheter shaft with a changing longitudinal extent of the balloon.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: October 20, 2020
    Assignee: INNORA GMBH
    Inventors: Uli Hanisch, Ulrich Speck
  • Patent number: 10799641
    Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing having an opening, a dose selector operable to set a dose by rotation relative to the housing, a release member controlling movement of a piston in a dispensing direction, and a display comprising a units number wheel and a tens number wheel which are coupled to each other such that a continuous rotation of the units number wheel is translated into an intermittent rotary motion of the tens number wheel. The release member rotates, during dose dispensing, an angle corresponding to the dose set by the dose selector, thereby allowing a piston to move in a dispensing direction.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: October 13, 2020
    Assignee: Sanofi
    Inventors: Joseph Butler, Anthony Paul Morris, William Geoffrey Arthur Marsh, Matthew Meredith Jones
  • Patent number: 10792174
    Abstract: A bariatric device and method of causing at least partial satiety in a recipient includes positioning a body in a recipient, the body having a wall defining a lumen, the wall configured to generally conform to the shape and size of the proximal cardiac portion of the stomach. Force is exerted with the wall on the proximal cardiac portion of the stomach in the absence of food thereby activating receptors located in the proximal cardiac portion of the stomach, thereby influencing a neurohormonal feedback mechanism of the recipient to cause at least partial satiety by augmenting fullness caused by food and simulating fullness in the absence of food.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: October 6, 2020
    Assignee: BFKW, LLC
    Inventors: Randal S. Baker, Paul R. Kemmeter, James A. Foote
  • Patent number: 10780248
    Abstract: A needle-injection catheter includes a catheter body having a distal end, a proximal end, a stiff proximal portion, a flexible distal portion, and a delivery lumen extending therethrough. In a first embodiment, a straight injection needle extends coaxially from a distal tip of the flexible portion of the catheter body, and a plurality of penetration limiting elements positioned circumferentially about a base of the straight injection needle and configured to fold radially inwardly against a shaft of the needle when constrained in a tubular lumen and to extend radially outwardly when unconstrained. In a second embodiment, a helical needle extends from the distal tip of the flexible portion of the catheter body. The helical needle has at least one helical delivery lumen connected to receive an injectable substance from the delivery lumen of the catheter body.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: September 22, 2020
    Assignee: BioCardia, Inc.
    Inventors: Wai Hsueh, Olin Jay Palmer, Scott Comiso, James B. Ross, Ken Vien, Julio Argentieri, Peter Altman
  • Patent number: 10780230
    Abstract: An autoinjector having a body (1) receiving a reservoir (S) containing fluid and a piston (P); a piston rod (5) movable by an injection spring (8) between a primed position and an injection position; and a visual, audible, and/or tactile indicator for indicating the autoinjector may be removed from the injection site. The autoinjector including a retarding system for delaying actuation of the indicator relative to the end of injection, and including a dashpot (16) containing a fluid, a piston (19) in the dashpot, the dashpot or the piston movable in the body during actuation of the retarding system with the other stationary relative to the body, resulting in the fluid moving out from the dashpot through a flow passage (161; 195) to brake movement.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: September 22, 2020
    Assignee: APTAR FRANCE SAS
    Inventors: David Fabien, Thomas Gomez, Anthony Saussaye, Olivier His
  • Patent number: 10780221
    Abstract: Aspects of the invention are related to a method and a system for administrating an infusion liquid pulse. The system includes a tubing system having an inlet connected to an external reservoir adapted to contain infusion fluids and an outlet connected to a catheter. The tubing system includes a check valve proximate to the inlet and an anti-siphon valve proximate to the outlet. The system further includes an automatic pulse flow generation device. The automatic pulse flow generation device includes an internal reservoir and a bidirectional pump configured to pump infusion fluid from the external reservoir to the internal reservoir and further pump an infusion fluid pulse from the internal reservoir to be injected by the catheter, the infusion liquid pulse has a volume of at least 2 ml and a velocity of at least 5 ml/min.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: September 22, 2020
    Assignee: Medical Flow Systems Ltd.
    Inventor: Ofer Shay
  • Patent number: 10765816
    Abstract: A syringe safety device is disclosed herein that comprises a shaft configured to support a barrel of a syringe, a guard configured to be disposed inside the shaft before the syringe is used and to extend outwardly from the shaft after the syringe is used, and a lock disposed between the guard and the shaft having a lock head disposed at a first end thereof, the lock head being disposed in a first aperture in the shaft before the syringe is used and in a second aperture in the shaft after the syringe has been used. A method of using the device also is described.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: September 8, 2020
    Inventor: Gina DiGiacomo
  • Patent number: 10765439
    Abstract: Provided is a treatment method of being able to improve the obstruction of a biological lumen caused by stenosis of the biological lumen and the stagnation of a secretion. The treatment method includes a disposition step of disposing a dilation portion that can be dilated and deflated, and a collection portion, which is capable of removing a secretion S secreted from a biological lumen from a living body, in a stenosed site occurring in the biological lumen; a dilation step of widening the stenosed site after the disposition step by dilating the dilation portion in the stenosed site after the disposition step; and a removal step of removing the secretion from the living body by a removal portion.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: September 8, 2020
    Inventors: Kouhei Watanabe, Takayuki Mouri, Risa Hoshino, Akihiko Tarunaga
  • Patent number: 10765815
    Abstract: A pneumatically activated retractable-needle syringe comprising a syringe barrel, a plunger, a needle, a needle hub, a locking tip, a propellant gas release cell and a rupture mechanism is provided. The plunger has a retraction lumen defined therein for receiving the needle when the retractable-needle syringe is actuated.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: September 8, 2020
    Assignee: L.O.M. Laboratories Inc.
    Inventors: Scott E. Castanon, Ralph E. Woloschuk, Warren Marc Terry
  • Patent number: 10758681
    Abstract: A safety needle and hub module for selective connection with a medical device that includes a base and a head. The module includes a needle shield for selectively covering a distal end of a needle. A needle hub is movably received within a proximal opening of the needle shield, and extends through a passageway of the needle shield. An actuation button is movably received in opposing lateral apertures of the needle shield to engage the needle shield, the needle hub and the medical device. In a first position an upper leg of the actuation button is received in a recess of the needle hub, and a lower leg of the actuation button is received in an undercut between the base and head of the medical device. In a second position, after the actuation button is actuated, the module is removable from the medical device.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: September 1, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Charles Hwang, Ralph Sonderegger
  • Patent number: 10758675
    Abstract: The embodiments described herein may relate to methods and systems for adjusting insulin delivery. Some methods and systems may be configured to adjust insulin delivery to personalize automated insulin delivery for a person with diabetes. Such personalization may include receiving and/or determining one or more user specific dosage parameters.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: September 1, 2020
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Bryan Mazlish, Lane Desborough, Ross Naylor
  • Patent number: 10758713
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: September 1, 2020
    Assignee: Neurotronic, Inc.
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang
  • Patent number: 10751512
    Abstract: An intravenous (IV)catheter apparatus comprising: a tubular catheter (10) having a proximal end (50) and a distal end (16) mounted to a catheter hub (40); a needle (12) defining an axial direction (A) having a needle shaft (22) with a needle tip (14) at a distal end (16) and a needle hub mounted to the proximal end (50) of the needle shaft (22); a needle guard (30) arranged movably on the needle shaft (22), wherein said needle shaft (22) extends through said tubular catheter (10) such that said needle tip (14) of said needle (12) protrudes from said distal end (16) of said tubular catheter (10); and wherein said needle shaft (22) is provided with: an engagement means (26) adapted to engage with the said needle guard (30) in order to prevent said needle guard (30) from sliding off said needle tip (14); and one or more lateral openings (28) covered by said tubular catheter (10).
    Type: Grant
    Filed: October 13, 2014
    Date of Patent: August 25, 2020
    Inventor: Rishi Baid
  • Patent number: 10751280
    Abstract: The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: August 25, 2020
    Assignee: NanoVault Medical LLC
    Inventors: Willard W. Hennemann, Bryan L. Steelman, Thomas J. Webster
  • Patent number: 10744262
    Abstract: A biosensor is implemented in an earpiece and includes an activity monitoring circuit that detects an activity level of a user and an optical circuit that detects a plurality of spectral responses at a plurality of wavelengths from light reflected from skin of the user. The biosensor determines a heart rate and an oxygen saturation level using the plurality of spectral responses and determines whether the heart rate or the oxygen saturation level reaches a predetermined threshold for the activity level of the user. The biosensor generates an alert and transmits the alert wirelessly to a remote device.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: August 18, 2020
    Inventors: Robert Steven Newberry, Matthew Rodencal