Patents Examined by Mark V Stevens
  • Film-forming compositions for the film-coating of solid forms
    Patent number: 11033504
    Abstract: The invention relates to a film-forming composition comprising a fluidised hydroxypropyl starch and sorbitol, and to a film-coating method using said composition. The invention further relates to film-coated solid forms comprising a fluidised hydroxypropyl starch and sorbitol in the coating.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: June 15, 2021
    Assignee: ROQUETTE FRERES
    Inventors: Xavier Parissaux, Gregory Le Bihan, Sebastien Croquet
  • Drug-containing patch
    Patent number: 11020356
    Abstract: The patch of the present invention comprises a backing layer and an adhesive layer laminated on the backing layer, wherein a water vapor transmission rate of the backing layer is 400 g/m2ยท24 hours or more, and the adhesive layer comprises a drug, dimethylsulfoxide and an adhesive. Such a patch does not fall off easily even after long wear.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: June 1, 2021
    Assignee: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Ryo Tanaka, Hideaki Ohashi, Naruhide Miyoshi, Takito Shima, Naoko Fujita, Yasunari Michinaka
  • Ganetespib-containing particle, pharmaceutical composition comprising the same, and their use in anticancer treatment
    Patent number: 11013720
    Abstract: Disclosed herein is a ganetespib-containing particle, which includes an active ingredient selected from ganetespib, a pharmaceutically acceptable salt of ganetespib, and a combination thereof, and an amphiphilic chitosan-based carrier carrying the active ingredient. Also disclosed herein are a pharmaceutical composition including the ganetespib-containing particle, and use of such pharmaceutical composition in treating cancer.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: May 25, 2021
    Assignee: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: Yan-Hwa Wu Lee, Dean-Mo Liu, Wei-Ting Huang, Ru-Tsun Mai, Yi-Hsin Chen
  • Combination therapy to achieve enhanced antimicrobial activity
    Patent number: 11007216
    Abstract: Techniques regarding enhancing antimicrobial activity of antirheumatic agents by combination therapy are provided. For example, one or more embodiments described herein can regard a chemical composition comprising a polycarbonate polymer functionalized with a guanidinium functional group. The chemical composition can also comprise an antirheumatic agent, and the polycarbonate polymer can enhance an antimicrobial activity of the antirheumatic agent.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: May 18, 2021
    Assignees: INTERNATIONAL BUSINESS MACHINES CORPORATION, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: James L. Hedrick, Yi Yan Yang, Xin Ding, Chuan Yang
  • Opioid receptor modulator dosage formulations
    Patent number: 11007179
    Abstract: Abuse deterrent solid dosage formulations containing 5-({[2-Amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-4,5-dihydro-1H-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid, and processes for the preparation and administration of these formulations.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: May 18, 2021
    Assignee: Allergan Holdings Unlimited Company
    Inventors: Tim Costello, Jens Jozef Ceulemans, Eugeen Maria Jozef Jans, Philip Erna H. Heyns
  • Highly stable biodegradable gene vector platforms for overcoming biological barriers
    Patent number: 11007279
    Abstract: A major challenge in non-viral gene delivery remains finding a safe and effective delivery system. Colloidally stable non-viral gene vector delivery systems capable of overcoming various biological barriers, are disclosed. The gene vectors are biodegradable, non-toxic and highly tailorable for use in specific applications. The vectors include a mixture of biodegradable copolymers, such as PBAE, and biodegradable polymers conjugated with hydrophilic, neutrally charged polymer, such as PEG. The gene vectors demonstrate broad vector distribution and high transgene delivery in vivo, providing an efficient non-viral gene delivery system for localized therapeutic gene transfer. Methods of using the vectors to overcome biological barriers including mucus gel and extracellular matrix are provided. Methods of formulating the vectors are also provided.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: May 18, 2021
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Justin Hanes, Jung Soo Suk, Panagiotis Mastorakos
  • Trace elements
    Patent number: 11000544
    Abstract: A trace element solution comprises at least the following metals: zinc; manganese; selenium; and copper; and which comprises a concentration of the metals of at least 90 mg/ml. The solution may comprise the following concentrations: at least 60 mg/ml zinc; at least 10 mg/ml manganese; at least 5 mg/ml selenium; and at least 15 mg/ml copper. The solution may comprise chromium, iodine and chromium.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: May 11, 2021
    Assignee: Warburton Technology Limited
    Inventor: William Alfred Smith
  • Method and composition for treating upper respiratory tract inflammatory and infectious diseases
    Patent number: 10993909
    Abstract: A composition and method for treating a mammal infected with a virus therein, and an inhalation delivery system for prevention and treatment of upper respiratory tract viruses, by administering a therapeutic dose of the composition to the mammal. The composition includes: microparticles and/or nanoparticles, wherein a pharmaceutically active agent, corticosteroid and/or hydroxychloroquine, niclosamide, and/or favipiravir, and a zinc salt are incorporated in the microparticles and/or nanoparticles. The pharmaceutically active agent is unfractionated heparin (UFH), Low Molecular Weight Heparin (LMWH), sulfated non-anticoagulant heparin (S-NACH), other glycosaminoglycans (GAGs), or combinations thereof.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: May 4, 2021
    Assignee: Virothera Pharmaceuticals LLC
    Inventor: Shaker A. Mousa
  • Osteoconductive and osteoinductive implant for augmentation, stabilization, or defect reconstruction
    Patent number: 10987448
    Abstract: Aspects of the present invention provide implants for augmentation, stabilization, or defect reconstruction of bone tissue, comprising a scaffold portion structured to provide shape to the implant, the scaffold portion comprising one or more of the following: one or more polylactic acid isomer; one or more polyglycolic acid isomer; and/or allogenic bone material, or similar compound.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: April 27, 2021
    Assignee: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Jessica A. Ching, Jonathan Michael Ford, Summer Joy Decker
  • Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
    Patent number: 10980739
    Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: April 20, 2021
    Assignee: Progenity, Inc.
    Inventors: Mitchell Lawrence Jones, Christopher Loren Wahl, Sharat Singh, Harry Stylli, Allison Luo
  • Sand remover for skin and hair
    Patent number: 10973756
    Abstract: Sand is an irritant to people and animals. The application of the sand remover powder mixture consisting of 40% montmorillonite and 60% Maranta arundinacea and rubbed/wiped removes sand from effected areas of skin and hair on humans and animals better together than in their individual natural state. In some embodiments sand remover powder can contain fragrance. Sand remover powder and rubbing/wiping can be used to remove residue from hair. Sand remover powder can be used as a body powder. Some sand remover powder embodiments can be ingested.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: April 13, 2021
    Inventors: Marla Christianne Deck, David Aaron Deck
  • Therapeutic detoxification compositions and methods of making and using same
    Patent number: 10960022
    Abstract: A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture; the second component comprises a bimodal synthetic carbon particle mixture and an anion exchange resin and the third component comprises a bimodal synthetic carbon particle mixture and a cation exchange resin.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: March 30, 2021
    Assignee: Immutrix Therapeutics, Inc.
    Inventors: Carol A Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Fragrance materials
    Patent number: 10952951
    Abstract: The present application relates to perfume raw materials, perfumes, perfume delivery systems and consumer products comprising such perfume raw materials, perfumes and/or such perfume delivery systems, as well as processes for making and using such perfume raw materials, perfume delivery systems and consumer products. The perfumes disclosed herein expand the perfume communities' options.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: March 23, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Jonathan Robert Cetti, Zerlina Guzdar Dubois, Virginia Tzung-Hwei Hutchins, Michael Wayne Kinsey, Christine Marie Readnour, Christelle Marie Sandrine Bonnet, Lynette Anne Makins Holland, Fabienne Pastor, Jose Maria Velazquez Mendoza, Jonathan Richard Stonehouse, William Eoghan Staite
  • Amino acid compositions to promote endothelial health
    Patent number: 10945979
    Abstract: Amino acid compositions for promoting vascular endothelial health include arginine, citrulline, and taurine. Compositions may be combined with additional ingredients to form beverages, concentrates, and non-liquid food compositions. Methods of making concentrate compositions, beverage compositions, and non-liquid food compositions are provided. Methods of administering compositions to improve endothelial health, treat endothelial dysfunction, treat sexual dysfunction, treat altitude sickness, treat decompression sickness, treat jet lag, and treat fatigue include administering compositions including arginine, citrulline, and taurine.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: March 16, 2021
    Inventor: Carl Louis Schroeder
  • Composite insecticidal composition
    Patent number: 10945436
    Abstract: A composite insecticidal composition is disclosed that contains three active ingredients, which are transfluthrin, prallethrin, and cypermethrin. The composite insecticide composition may further contain at least one of a solvent and a propellant. The weight percentage of each of the active ingredients may be about 0.05% to 0.5%.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: March 16, 2021
    Assignee: S. C. Johnson & Son, Inc.
    Inventor: Bhaveshkumar Shah
  • Bicarbonate as a potentiator for antimicrobial agents
    Patent number: 10940163
    Abstract: Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: March 9, 2021
    Assignee: McMaster University
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Jonathan Stokes
  • Pharmaceutical composition for the treatment of autism
    Patent number: 10940140
    Abstract: The present invention relates to a pharmaceutical composition or a kit comprising, a first substance capable of raising intracellular cAMP levels, and a second substance capable of modulating intracellular calcium concentration. Likewise, the present invention relates to methods of treating patients suffering from autism spectrum disorder (ASD) phenotype 1 by administering an effective amount of a substance capable of raising intracellular cAMP levels and, optionally, an effective amount of a substance capable of modulating intracellular calcium concentration.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: March 9, 2021
    Assignee: Stalicla S.A.
    Inventor: Lynn Durham
  • Aqueous solutions of copper salts and hydrogen peroxide
    Patent number: 10940228
    Abstract: Aqueous compositions, methods of manufacturing such aqueous compositions, and methods of removing reducing and/or suppressing malodours using such aqueous compositions are described. These compositions utilize a combination of hydrogen peroxide, a source of copper II, nonionic surfactant and alcohol to provide a highly effective and stable malodour removing, reducing and/or suppressing composition. The compositions are particularly useful as aerosol compositions for effective malodour removal, reduction and/or suppression in particular malodours from open sites such as landfill and in closed domestic environments such as the home. Also described is a stabilized hydrogen peroxide solution, which is stable on the addition of copper (II) salts.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: March 9, 2021
    Assignee: 2PURE PRODUCTS LIMITED
    Inventor: Peter Carty
  • Antibacterial cryogel and porous hydrogel, their preparation method, and their use for disinfecting water
    Patent number: 10939677
    Abstract: The invention relates to an antibacterial cryogel, its preparation method, and its use for disinfecting water. The invention further relates to an antibacterial porous hydrogel.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: March 9, 2021
    Assignee: Nanyang Technological University
    Inventors: Xiao Hu, Siew Leng Loo, Anthony G. Fane, Teik Thye Lim, William B. Krantz
  • Particle containing at least a volatile substance and process for its preparation
    Patent number: 10933023
    Abstract: The invention is directed to a particle containing at least a volatile substance comprising a core comprising at least one matrix material and the at least one volatile substance and at least one coating layer, whereby a first coating layer is a non-confluent layer comprising at least a carrier material, whereby optionally the non-confluent layer contains at least one hydrophobic substance, and optionally the particle is surrounded by at least one confluent layer and/or further non-confluent layer(s) as well as to a process for producing the same.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: March 2, 2021
    Assignee: ERBER AKTIENGESELLSCHAFT
    Inventors: Pia Gottschalk, Eva-Maria Binder, Franz Waxenecker, Carina Schieder, Anne-Christine Hunger, Stephen Charles John Cole