Patents Examined by Mark W Bockelman
  • Patent number: 11679256
    Abstract: A method of replacing a neurostimulator device. The method including explanting a previously implanted neurostimulator device from a site; operably coupling a replacement neurostimulator device to a previously implanted stimulation lead; and implanting a replacement neurostimulator device within the site, the replacement neurostimulator device having a volume of about ten cc's or less, and the previously implanted neurostimulator device having a volume of greater than about ten cc's.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: June 20, 2023
    Assignee: Medtronic, Inc.
    Inventors: Robert T. Sandgren, Elizabeth K. Formosa, Kathryn E. Aman, Steven Deininger, Paul Eichstaedt, Randy S. Roles
  • Patent number: 11672464
    Abstract: Systems and methods are provided for analyzing electrocardiogram (ECG) data of a patient using a substantial amount of ECG data. The systems receive ECG data from a sensing device positioned on a patient such as one or more ECG leads. The system may include an application that communicates with an ECG platform running on a server(s) that processes and analyzes the ECG data, e.g., using neural networks for delineation of the cardiac signal and classification of various abnormalities, conditions and/or descriptors. The processed ECG data is communicated from the server(s) for display in a user-friendly and interactive manner with enhanced accuracy.
    Type: Grant
    Filed: October 18, 2021
    Date of Patent: June 13, 2023
    Inventors: Jia Li, Romain Pomier, Chiara Scabellone, Cyril Gaudefroy, Benjamin Barre, Julien Fontanarava, Christophe Gardella, Mathieu Sornay, Thomas Bordier
  • Patent number: 11672490
    Abstract: A sensor interface system for providing a connection between at least one sensor and a maternal-fetal monitor, wherein the interface system converts electrical muscle activity captured by the sensor(s) into uterine activity data signals for use by the maternal-fetal monitor. The sensor interface system of the invention preferably includes a conversion means for converting the signals from the sensor(s) into signals similar to those produced by a tocodynamometer.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: June 13, 2023
    Inventors: Neil Russell Euliano, II, Dorothee Marossero, Shalom Darmanjian, Daniel Patrick McKenna
  • Patent number: 11666483
    Abstract: A first optical subsystem includes a window with a refractive index nw and an exit lens having a refractive index nx. The exit lens is configured to couple to the window to define a first optical axis extending through the window and the exit lens. A second optical subsystem is configured to output a light beam. The light beam is directed to be incident at a convex surface of the exit lens along a second optical axis at an angle ? that is offset from the first optical axis. The window is configured to detachably couple to the cornea of the eye such that the first optical axis is generally aligned with a direction of view of the eye. The respective refractive indices nw and nx are configured to direct the light beam incident at the convex surface of the exit lens through the cornea of the eye toward the irido-corneal angle.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: June 6, 2023
    Assignee: ViaLase, Inc.
    Inventor: Ferenc Raksi
  • Patent number: 11660314
    Abstract: A device intended to be implanted in a human or animal body, in order to produce hydrogen in situ from molecules present in the body medium in which the device is implanted, this device having an anode and a cathode, which are each electrically connected to a pole of an electrical energy source, and having a semi-permeable material separating the electrodes from the body medium, in which device, when the connection to the electrical energy source is effective in situ, in the presence of body fluid, a closed electrical circuit is formed, with production of hydrogen at the cathode, the semi-permeable material having a cutoff threshold of between 50 and 500 Da.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: May 30, 2023
    Inventors: Philippe Cinquin, Abdelkader Zebda, Jean-Pierre Alcaraz, Donald Keith Martin
  • Patent number: 11654159
    Abstract: Stimulation using EA of LI-4, LI-11, GV-14 and GV-20 in humans, horses, and rodents results in mobilization of MSCs into systemic circulation. Methods are provided for increasing mesenchymal stem cells in the circulating blood of a mammal by contacting acupuncture points LI-4, LI-11, GV-14, and GV-20 of the mammal with a therapeutically effective amount of EA stimulation to mobilize MSCs into the circulating blood of the mammal. Methods for treating damaged tissue, specifically damaged tendons are also provided. Isolated mesenchymal stem cells made according to these methods, methods of isolated them, and stem cell banks that store them are also provided.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: May 23, 2023
    Inventors: Maria A. Grant, Tatiana E. Salazar, Huisheng Xie
  • Patent number: 11648399
    Abstract: An example of an apparatus for percutaneously delivering neurostimulation energy to a patient and sensing from the patient using a test device placed externally to the patient is provided. The apparatus may include a stimulation lead, a sensing reference electrode, a sensing wire, and a connection system. The stimulation lead may be configured to be percutaneously introduced into the patient to place the one or more electrodes in the patient. The sensing reference electrode may be configured to be placed in the patient. The sensing wire may be connected to the sensing reference electrode and configured to be percutaneously introduced into the patient to place the sensing reference electrode in the patient. The connection system may be configured to mate the lead connector and the wire connector and to provide electrical connections between the lead connector and the test device and between the wire connector and the test device.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: May 16, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Joseph M. Bocek, Michael X. Govea, Rosana Esteller
  • Patent number: 11638814
    Abstract: The present disclosure provides a neuromodulation method for treating neurodegenerative disease. The neuromodulation method comprises attaching a first active electrode to a patient's leg in the back of the knee area in an expected location of a peroneal nerve of the first leg and attaching a grounding electrode to the patient's body. Generating electrical pulses by a pulse generator connected to the first active electrode and the grounding electrode. Stimulating by the first active electrodes the peroneal nerve of the first leg and controlling via a control unit a flow of the generated pulses to the first electrode.
    Type: Grant
    Filed: April 20, 2022
    Date of Patent: May 2, 2023
    Assignee: TESLA MEDICAL S.R.O.
    Inventors: Lukas Doskocil, Jan Krhut, Lukas Peter, Michal Drahos, Zdenek Krcil
  • Patent number: 11633607
    Abstract: An implantable medical system may provide atrioventricular synchronous pacing using the ventricular septal wall. The system may include a ventricular electrode coupled to an intracardiac housing or a first medical lead implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the left ventricle of the patient's heart and a right atrial electrode coupled to a leadlet or second medical lead to deliver cardiac therapy to or sense electrical activity of the right atrium of the patient's heart. A right ventricular electrode may be coupled to the intracardiac housing or the first medical lead and implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the right ventricle of the patient's heart.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: April 25, 2023
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: 11633586
    Abstract: A catheter pump is disclosed. The catheter pump can include an impeller and a catheter body having a lumen therethrough. The catheter pump can also include a drive shaft disposed inside the catheter body. A motor assembly can include a chamber. The motor assembly can include a rotor disposed in the at least a portion of the chamber, the rotor mechanically coupled with a proximal portion of the drive shaft such that rotation of the rotor causes the drive shaft to rotate. The motor assembly can also comprise a stator assembly disposed about the rotor. The motor assembly can also include a heat exchanger disposed about the stator assembly, the heat exchanger may be configured to direct heat radially outward away from the stator assembly, the rotor, and the chamber.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: April 25, 2023
    Assignee: TC1 LLC
    Inventors: Adam R. Tanner, Michael R. Butler, Todd Jenkins
  • Patent number: 11633612
    Abstract: A hermetically sealed feedthrough assembly for an active implantable medical device having an oxide-resistant electrical attachment for connection to an EMI filter, an EMI filter circuit board, an AIMD circuit board, or AIMD electronics. The oxide-resistant electrical attachment, including an oxide-resistant sputter layer 165 is disposed on the device side surface of the hermetic seal ferrule over which an ECA stripe is provided. The ECA stripe may comprise one of a thermal-setting electrically conductive adhesive, an electrically conductive polymer, an electrically conductive epoxy, an electrically conductive silicone, an electrically conductive polyimides, or an electrically conductive polyimide, such as those manufactured by Ablestick Corporation. The oxide-free electrical attachment between the ECA stripe and the filter or AIMD circuits may comprise one of gold, platinum, palladium, silver, iridium, rhenium, rhodium, tantalum, tungsten, niobium, zirconium, vanadium, and combinations or alloys thereof.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: April 25, 2023
    Assignee: Greatbatch Ltd.
    Inventors: Christine A. Frysz, Robert A. Stevenson, Jason Woods
  • Patent number: 11628299
    Abstract: The present disclosure relates to subcutaneous direct current (DC) nerve conduction block. A subcutaneous electrode can be implanted under a subject's skin between the subject's skin and a neural structure within the subject's body. The subcutaneous electrode can be coupled to a current generator. A DC can be configured by the current generator and delivered through the subcutaneous electrode to block conduction in the neural structure. The subcutaneous electrode eliminates an effect of an impedance of the subject's skin on the DC. The DC can be returned to the current generator by a return electrode.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: April 18, 2023
    Inventors: Tina Vrabec, Niloy Bhadra, Narendra Bhadra, Kevin L. Kilgore
  • Patent number: 11623091
    Abstract: The present disclosure is directed to a portable system and method for modulating targeted neural and non-neural tissue of a nervous system to block nerve conduction for the treatment of pain. A high-efficiency portable electrical stimulation system is provided that allows a user to carry the system and move around freely while continuously receiving therapy. The electronic control system is configured to deliver high-frequency electrical stimulation at a therapeutic level, for an intended duration (e.g., up to 24 hours or more) at a manageable and/or comfortable weight for a person, to the target nerve.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: April 11, 2023
    Assignee: Avent, Inc.
    Inventors: Wanzhan Liu, Chris Zobkiw, Gleb Klimovitch, Ryan Caldwell, Eric A. Schepis, Phillip A. Schorr, Jalpa Shah
  • Patent number: 11617884
    Abstract: Chronic pain management can be achieved by electrically anesthetizing a peripheral nerve with on-demand electrical nerve block (OD-ENB). OD-ENB can be provided by an implantable capsule. Externally, at least a portion of the capsule can be constructed of a conductive membrane and the rest of the capsule comprises a biocompatible material. A blocking electrode contact, a return electrode contact, and a powering/communication component can be within the capsule. The blocking electrode contact can deliver a direct current (DC) through a portion of the conductive membrane to block conduction in the neural tissue to provide the OD-ENB. The return electrode contact can receive a return current from the neural tissue through another portion of the conductive membrane. The powering/communication component can communicate with one or more external components located external to the patient's body to receive a power signal. Notably the capsule has no internal battery.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: April 4, 2023
    Inventors: Tina L. Vrabec, Kevin L. Kilgore, Jesse S. Wainright, Niloy Bhadra
  • Patent number: 11617879
    Abstract: An implantable medical device (IMD) has a housing enclosing an electronic circuit. The housing includes a first housing portion, a second housing portion and a joint coupling the first housing portion to the second housing portion. A polymer seal is positioned in the joint in various embodiments. Other embodiments of an IMD housing are disclosed.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: April 4, 2023
    Assignee: Medtronic, Inc.
    Inventors: Brad C. Tischendorf, John E. Kast, Thomas P. Miltich, Gordon O. Munns, Randy S. Roles, Craig L. Schmidt, Joseph J. Viavattine, Christian S. Nielsen, Prabhakar A. Tamirisa, Anthony M. Chasensky, Markus W. Réitérer, Chris J. Paidosh, Reginald D. Robinson, Bernard Q. Li, Erik R. Scott, Phillip C. Falkner, Xuan K. Wei, Eric H. Bonde
  • Patent number: 11612751
    Abstract: Methods and systems for programming stimulation parameters for an implantable medical device for neuromodulation, such as spinal cord stimulation (SCS) are disclosed. The stimulation parameters define user-configured waveforms having at least a first phase having a first polarity and a second phase having a second polarity, wherein the first and second phases are separated by an interphase interval (IPI). By delivering user-configured waveforms with different IPIs, stimulation geometry, and other waveform settings, therapeutic asynchronous activation of dorsal column fibers can be obtained.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: March 28, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Tianhe Zhang, Rosana Esteller
  • Patent number: 11596798
    Abstract: Systems and methods for treating congestive heart failure with high frequency stimulation are disclosed. A representative method for treating a patient includes applying an electrical signal having a frequency of from about 1 kHz to about 100 kHz to the patient via a treatment system that includes a signal delivery element in electrical communication with the patient's vagus nerve at a portion of the vagus nerve located at or proximate to the anterior interventricular junction of the patient's heart. The method can further include automatically detecting at least one physiological parameter of the patient, automatically determining at least one of an ejection fraction of the patient's heart and a correlate of the ejection fraction based on the detected parameter, and automatically adjusting the applied signal based on the determined ejection fraction.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: March 7, 2023
    Assignee: Nevro Corp
    Inventors: James R. Thacker, Kerry Bradley
  • Patent number: 11601067
    Abstract: This application describes a variety of approaches for generating high voltage sinusoidal signals whose output voltage can be adjusted rapidly, without introducing high-frequency artifacts on the output. When these approaches are used, stronger electric fields can be applied to the tumor for a higher percentage of time, which can increase the efficacy of TTFields therapy. In some embodiments, this is accomplished by preventing adjustments to a DC power source during times when the output of that DC power source is powering the output signal. In some embodiments, this is accomplished by synchronizing the operation of an AC voltage generator and an electronic switch that is connected to the output of the AC voltage generator.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: March 7, 2023
    Assignee: Novocure GmbH
    Inventor: Yoram Wasserman
  • Patent number: 11571568
    Abstract: Devices and methods can be used to treat dermatologic disorders, hyperhidrosis, and wrinkles using DC electroporation. In some cases, such electroporation is essentially non-thermal modulation that can be used to ablate keratinocyte neoplasms, such as seborrheic keratosis, and other non-keratinocyte derived neoplasms of the skin and adnexal structures and related structures in other anatomic sites. In some implementations, the devices and methods described herein can be used for therapy delivery for the treatment of early or pre-malignant skin cancers. In some implementations, the devices and methods described herein can be used for treatment of hyperhidrosis and cosmetic issues.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: February 7, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Spencer A. Bezalel, Clark C. Otley, Samuel J. Asirvatham, Christian Lee Baum
  • Patent number: 11565123
    Abstract: A catheter device for use in the photodynamic treatment of a body cavity or hollow organ of the body, such as the bladder, the device being used in the photodynamic treatment of abnormalities, disorders or diseases of the internal surfaces of said body cavity or hollow organ.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: January 31, 2023
    Assignee: PHOTOCURE ASA
    Inventors: Tore Gjørsvik, Aslak Godal, Roger William Rolfe Warren