Patents Examined by Mary C. Lee
  • Patent number: 5326865
    Abstract: Arylazo and poly(arylazo) dyes having at least one core radical selected from naphthyl or anthracyl and having at least one 2,3-dihydro-1,3-dialkyl perimidine substituent, a guest-host composition comprising a liquid crystal host solvent and the arylazo or poly(arylazo) dichroic dye, and a liquid crystal display comprising the guest-host composition, are disclosed.
    Type: Grant
    Filed: June 8, 1990
    Date of Patent: July 5, 1994
    Assignee: Hercules Incorporated
    Inventors: Robert P. Grasso, Michael K. O'Brien, Paul J. Shannon
  • Patent number: 5326866
    Abstract: A liquid azo dye represented by the formula: ##STR1## (wherein, A stands for a phenylene group which may have a substituent, n is o or 1, Cp is a pyrazolone derivative residue or a naphthol derivative residue, X is --NH-- or --COO-- and R is an alkyl group having 3 to 12 carbon atoms).
    Type: Grant
    Filed: May 12, 1993
    Date of Patent: July 5, 1994
    Assignee: Orient Chemical Industries, Ltd.
    Inventors: Takashi Ono, Tatsuya Yagyu, Tetsui Akase
  • Patent number: 5326876
    Abstract: A process for preparing an alkyl sulfonate derivative comprises causing a nitrogen-containing heterocyclic compound represented by the following formula (1): ##STR1## wherein X represents --O--, --S--, --NR.sup.1 --, --Se--, --Te-- or --CR.sup.2 R.sup.3 --, in which each of R.sup.1, R.sup.2 and R.sup.3 independently represents a hydrogen atom or a lower alkyl group, Y represents a hydrogen atom, a mercapto group, an arylthio group, an aralkyl group, a sulfo group, a halogen atom, an alkyl group, an alkylthio group, an alkylsulfonyloxy group or an arylsulfonyloxy group and each of R.sup.4, R.sup.5, R.sup.6, R.sup.7 and R.sup.8 represents a hydrogen atom, an alkyl group, an aryl group, an alkoxy group which may be substituted with a sulfo group, an aryloxy group, an alkylthio group, a haloalkyl group, a halogen atom, a cyano group, a carboxy group or a sulfo group, otherwise R.sup.4 and R.sup.5, R.sup.6 and R.sup.6, R.sup.6 and R.sup.7 and R.sup.7 and R.sup.
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: July 5, 1994
    Assignee: Fuji Photo Film Co., Ltd.
    Inventor: Ken Kawata
  • Patent number: 5326878
    Abstract: Method of resolution of chiral hydantoins of the general formula I ##STR1## in which: R.sub.1 designates a lower alkyl radical comprising 1 to 5 carbon atoms in linear or branched chain,R.sub.2 designates a phenyl radical, possibly mono-, di-, or tri-substituted by lower alkyl or alkoxy radicals or halogen atoms, whether identical of different, or a heteroaryl radical containing a ring of 5 to 7 members in which the sole hetero atom is nitrogen, oxygen or sulfur, or else an aralkyl radical the alkyl part of which comprises one or two carbon atoms and the aryl ring is a phenyl group possibly mono-, di- or tri-substituted by radicals which are lower alkyl or alkoxy radicals or halogen atoms, whether identical or different. The hydantoin (I) to be resolved is dissolved in an alcohol or an alkaline solution, and an enantiomer of .alpha.
    Type: Grant
    Filed: July 21, 1992
    Date of Patent: July 5, 1994
    Assignee: Jouveinal SA
    Inventors: Dominique Depernet, Roger Bouaziz, Gerard Coquerel, Marie N. Petit
  • Patent number: 5326881
    Abstract: An unsaturated imide compound represented by formula (1): ##STR1## wherein Q is an alicyclic structure-containing hydrocarbon group having 4-20 carbon atoms; each of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.i and R.sub.j represents a hydrogen atom, a halogen atom, a hydrocarbon group having 1-6 carbon atoms or a halogen-containing hydrocarbon group having 1-6 carbon atoms; each of a, b, c, d, e and f represents an integer of 0 to 4 satisfying a+b.ltoreq.4, c+d.ltoreq.4 and e+f.ltoreq.4 and D represents a divalent organic group having 2-24 carbon atoms and an ethylenically unsaturated double bond, a process for producing the unsaturated imide compound of formula (1) and intermediates for producing the unsaturated imide compound of formula (1). The unsaturated imide compound of formula (1) is well soluble in organic solvents and can give cured products excellent in heat resistance, low water absorption and flexibility.
    Type: Grant
    Filed: October 28, 1993
    Date of Patent: July 5, 1994
    Assignee: Sumitomo Chemical Company Ltd.
    Inventors: Yasuhiro Hirano, Yasuhiro Endo, Kazuo Takebe, Mitsuhiro Shibata, Shuichi Kanagawa, Yutaka Shiomi, Masatsugu Akiba, Shinichiro Kitayama
  • Patent number: 5324741
    Abstract: The compounds of formula (I): ##STR1## wherein R is (CH.sub.3).sub.2 CHCH.sub.2 -- or (CH.sub.3).sub.3 CCH.sub.2 --, or R is the group CH.sub.3 --O--(R.sup.1)CH-- where R.sup.1 is hydrogen or methyl, or R is a cycloalkyl group containing from 3 to 6 carbon atoms have nematicidal activity and the present invention discloses a method for killing or controlling nematode pests which comprises applying to the locus of the pests or to a plant susceptible to attack by the pest an effective amount of a compound of formula (I).
    Type: Grant
    Filed: November 8, 1990
    Date of Patent: June 28, 1994
    Assignee: Imperial Chemical Industries plc
    Inventor: Michael D. Turnbull
  • Patent number: 5324826
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is C.sub.1-18 alkyl, substituted C.sub.1-18 alkyl, phenyl, substituted phenyl, C.sub.3-6 alkenyl, substituted C.sub.3-6 alkenyl, C.sub.3-6 alkynyl or substituted C.sub.3-6 alkynyl,R.sub.2 is an electron withdrawing substituent; andK is the residue of a coupling component that is free of any water solubilizing groups.The compounds are disperse dyes which can be used to dye, print or pad fully synthetic or semi-synthetic hydrophobic high molecular weight organic material.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: June 28, 1994
    Assignee: Sandoz Ltd.
    Inventor: Peter Matzinger
  • Patent number: 5322948
    Abstract: The present invention pertains to a method of preparing substituted and unsubstituted N-hydroxy-2-aminobutane diacid derivatives. The invention also pertains to the use of N-hydroxy-2-aminoethane derivatives (including the N-hydroxy-2-aminobutane diacid derivatives) in the preparation of pyridine derivatives.
    Type: Grant
    Filed: January 2, 1992
    Date of Patent: June 21, 1994
    Assignee: Hoechst Celanese Corporation
    Inventors: Varadaraj Elango, Donald R. Larkin, John R. Fritch, Michael P. Bodman, Werner H. Mueller, Bernard F. Gupton, John C. Saukaitis
  • Patent number: 5321036
    Abstract: Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof where A is ##STR2## R.sub.3 is --(CH.sub.2).sub.n -- or in the case where R.sub.2 is ##STR3## R.sub.3 in addition to the above may be ##STR4## R.sub.4 is hydroxy, alkoxy, amino, alkylamino or dialkylamino; R.sub.5 is hydrogen, fluorine, chlorine, bromine, iodine, --CN, CF.sub.3, lower alkyl, lower alkoxy, cycloalkyl or aryl;R.sub.6 is lower alkyl, cycloalkyl or aryl;R.sub.7, R.sub.7 ', R.sub.8 and R.sub.8 ' are independently hydrogen or a lower alkyl or R.sub.7 and R.sub.8 may together be CH.sub.2 CH.sub.2 ;Z is hydrogen or ##STR5## m is an integer of 1 or 2; n is zero or an integer of 1 to 6; andp is an integer of 1 to 5. These compounds are beta 3 adrenergic receptor agonists and are useful, therefore for example, in the treatment of diabetes, obesity and gastrointestinal diseases.
    Type: Grant
    Filed: February 10, 1993
    Date of Patent: June 14, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventor: Philip M. Sher
  • Patent number: 5321016
    Abstract: The invention discloses certain substituted .alpha.-aminoacids having the formula ##STR1## where m and n are 1 or 2, and R, R.sub.1, R.sub.2, R.sub.3 and Y have various significances, which compounds are useful in treating epilepsy, disorders associated with excess GH or LH secretion, anxiety, schizophrenia, depression, CNS degenerative disorders, cerebral hypoxic conditions and stress-related psychiatric disorders.
    Type: Grant
    Filed: September 18, 1992
    Date of Patent: June 14, 1994
    Assignee: Sandoz Pharmaceuticals Corp.
    Inventors: Paul L. Herrling, Werner Muller
  • Patent number: 5321041
    Abstract: Diphenylpyrrolyfuran derivatives represented by the following formula (I): ##STR1## wherein R.sub.1 and R.sub.2 may be the same or different and independently represent a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, or a lower alkylsulfenyl group; m and n independently represent an integer of from 1 to 3; R.sub.3 represents a hydrogen atom or a lower alkyl group, R.sub.4 represents a hydrogen atom, a lower alkyl group, or a lower acyl group; and R.sub.5 represents a hydrogen atom, a lower alkyl group which may have one or more suitable substituents, a lower alkoxy- or an aryloxy-carbonyl group, an acyl group, or a sufonyl group, and pharmaceutically acceptable salts thereof are disclosed. The compounds disclosed are useful as anti-inflammatory agent, anti-allergic agents, anti-platelet agents and the like.
    Type: Grant
    Filed: October 25, 1993
    Date of Patent: June 14, 1994
    Assignee: Nihon Iyakuhin Kogyo Co., Ltd.
    Inventors: Jun Adachi, Mitsugu Ishida, Toshietsu Taniguchi, Yuichi Kato, Toshiyuki Kawagoshi, Tomoaki Tamura, Tetsuo Kadozaki, Tetsuo Miyamoto
  • Patent number: 5319095
    Abstract: This invention provides a process for preparing kainic acid and provides intermediates in the synthesis thereof.
    Type: Grant
    Filed: December 4, 1992
    Date of Patent: June 7, 1994
    Assignee: Eli Lilly and Company
    Inventor: James A. Monn
  • Patent number: 5319097
    Abstract: The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxy-carbonyl)amino-1-methylindol-3-yl-methyl]-3-methox ybenzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-methoxy benzoyll-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. The compositions are useful in the treatment of diseases in which leukotrienes are implicated, for example asthma.
    Type: Grant
    Filed: December 11, 1991
    Date of Patent: June 7, 1994
    Assignee: Imperial Chemical Industries PLC
    Inventors: James J. Holohan, Ieuan J. Edwards
  • Patent number: 5319075
    Abstract: Mixtures of iron complexes of metallizable disazo compounds, at least one compound being of the formula ##STR1## and at least one compound being of the formula ##STR2## wherein the substituents have the meaning given in the specification, are useful for dyeing substrates dyeable with anionic dyes, e.g., leather.
    Type: Grant
    Filed: February 22, 1993
    Date of Patent: June 7, 1994
    Assignee: Sandoz Ltd.
    Inventors: Jordi Berenguer Barra, Herbert Holliger, Jose Rocas Sorolla
  • Patent number: 5317093
    Abstract: Bisazo compounds, useful as organic photoconductive materials, having formula (I) or (II) are disclosed: ##STR1## wherein R represents hydrogen, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a nitro group; ##STR2## wherein A and B independently represent hydrogen or chloride provided that either A or B represents chloride.
    Type: Grant
    Filed: September 19, 1991
    Date of Patent: May 31, 1994
    Assignee: Ricoh Company, Ltd.
    Inventor: Mitsuru Hashimoto
  • Patent number: 5315023
    Abstract: A process for the preparation of highly pure deacylated glycerophosphorylcholine, glycerophosphorylethanolamine and glicerophosphorylserine starting from mixtures of the corresponding acylated derivatives.The process according to the invention is characterized in that the deacylation reaction, by means of alcoholysis, and the fractionation are carried out in a single step in a reactor containing a basic ion-exchange resin.
    Type: Grant
    Filed: March 8, 1993
    Date of Patent: May 24, 1994
    Assignee: Chemi S.p.A.
    Inventors: Lorenzo De Ferra, Fausto Bonifacio, Guido Cifarelli, Pietro Massardo, Oreste Piccolo
  • Patent number: 5314997
    Abstract: An optically active azo compound is represented by the following general formula (I), ##STR1## where R is an alkyl group having from 1 to 20 carbon atoms, and R* is an optically active radical of an alkyl group or a halogen substituted alkyl group having from 1 to 10 carbon atoms. A liquid crystal composition contains this compound. A method for producing an optically active azo compound represented by the following general formula (I) has the step of reacting a phenol compound represented by the following general formula (II) with an optically active carboxylic acid represented by the following general formula (III) using a condensing agent at a room temperature.
    Type: Grant
    Filed: June 26, 1992
    Date of Patent: May 24, 1994
    Assignee: Ricoh Company, Ltd.
    Inventors: Masayuki Shoshi, Akihiko Kanemoto
  • Patent number: 5314863
    Abstract: Compounds of the formula (I) ##STR1## and their use as antidotes against the phytotoxicity of many herbicides used on crops, without diminishing the effect of the herbicide against weeds.
    Type: Grant
    Filed: June 25, 1992
    Date of Patent: May 24, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz J. Loher, Wilfried Schwab, Klaus Bauer, Hermann Bieringer
  • Patent number: 5315010
    Abstract: Polyaspartic acid having a weight average molecular weight of 1000 to 5000 is produced by hydrolysis of anhydropolyaspartic acid that has been produced by condensation polymerization of L-aspartic acid. Conversion in excess of 80 percent is achievable utilizing "temperature vs. time" profiles.
    Type: Grant
    Filed: June 21, 1993
    Date of Patent: May 24, 1994
    Assignee: Donlar Corporation
    Inventors: Larry P. Koskan, Kim C. Low, Abdul R. Y. Meah, Anne M. Atencio
  • Patent number: 5314998
    Abstract: Metal-azo dyes with excellent solubility in organic media are provided. The metal-containing dyes of the present invention have a nucleus of the formula: ##STR1## wherein the substituents have the meaning given in the description. Dye-donor sheets comprising the above-mentioned dyes are also disclosed.
    Type: Grant
    Filed: September 8, 1992
    Date of Patent: May 24, 1994
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Terrance P. Smith, David W. Macomber