Abstract: A method for providing pressure feedback is described herein. The method includes receiving, via a processor, pressure sensor data from a plurality of pressure sensors over a period of time. The method also includes receiving, via the processor, movement data from a plurality of sensors over the period of time. The method also further includes sending, via the processor, pressure sensor data and movement data to a data service. The method also includes receiving, via the processor, a feedback from data service.

Abstract: A minimally invasive medical instrument comprises an elongate flexible body including a proximal portion, a distal portion, an inner sheath defining a central lumen, and an outer sheath. The inner sheath comprises an inner surface and an outer surface. The instrument further comprises a plurality of conduits embedded within the inner sheath. The plurality of conduits extend through the inner sheath and terminate within the inner sheath. Each conduit includes a conduit lumen and a distal end, and the distal end is directly secured to the inner sheath. The instrument further includes at least one tendon extending through the conduit lumen of at least one conduit of the plurality of conduits from the proximal portion and beyond the distal end of the at least one conduit into the distal portion of the elongate flexible body. The at least one tendon is actuatable to steer the distal portion.

Abstract: Systems and methods for improving an interaction between a prosthetic and/or orthotic device (POD) and a user of the POD are described. In some cases, the POD monitors various parameters during gait and communicates the gait parameters to a remote monitoring device. The remote monitoring device can analyze the gait parameters in real-time to provide various indications of user-POD interactions including, but not limited to, symmetric weight bearing, rolling over the toe, sitting down, stair descent, and/or stair ascent. The remote monitoring device can further provide indications to improve the user-POD interactions.

Abstract: Devices and methods are provided for automatic vascular access. An automatic vessel cannulation device, mechanical or electronic, has a sensor configured to detect a physiologic parameter of a needle tip, and a blunting device advancing member released in response to the sensor. The sensor may measure pressure or any other physiological parameter. A processor is configured to analyze data sent by the sensor and is pre-set to identify parameters unique to arteries, veins, or other body cavities or organs. A method may include comparing a physiologic parameter with pre-determined parameters to deploy a blunting element if the physiologic parameter is within a range of the pre-determined parameters. An expandable sheath may be included. A device can be provided having a motor controlling the cannulation device orientation to scan tissue with the tip of the needle by moving the cannulation device through the ultrasound transducer.

Abstract: A non-invasive system for sampling gastrointestinal microbiota with their associated environment for discovery, characterization, medical research, diagnostics, and treatment using an ingestible, non-digestible sampling capsule. The capsule device, with ports open for acquiring a sample of gastrointestinal microbiota and content, is placed inside an immediate or delayed release capsule. When the outer capsule dissolves according to its specifications, enteric fluid and content enters the sampling capsule through the ports triggering a hydrophilic stop to release a pulling force to close the ports by enveloping the capsule outer casing over the inner casing, capturing the sample, and holding it sealed until it completes passage through the digestive track, and is recovered from feces for analysis.

Abstract: A physiological acoustic monitoring system receives physiological data from an acoustic sensor, down-samples the data to generate raw audio of breathing sounds and compresses the raw audio. The acoustic monitoring system has an acoustic sensor signal responsive to tracheal sounds in a person. An A/D converter is responsive to the sensor signal so as to generate breathing sound data. A decimation filter and mixer down-samples the breathing sound data to raw audio data. A coder/compressor generates compressed audio data from the raw audio data. A decoder/decompressor decodes and decompresses the compressed audio data into decompressed audio data. The decompressed audio data is utilized to generate respiration-related parameters in real-time. The compressed audio data is stored and retrieved so as to generate respiration-related parameters in non-real-time. The real-time and non-real-time parameters are compared to verify matching results across multiple monitors.

Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

Abstract: A needle holder for a tissue sampling device, such as a biopsy gun, may include a receptacle, a cradle within the receptacle, and a cover that interacts with a lock on a biopsy needle set when the cover is closed. The biopsy needle set may include a needle hub that carries a proximal end of a needle, a cannula hub that carries a proximal end of a cannula positioned over a portion of the needle, and a lock. The lock may have a locked arrangement that holds the needle hub and the cannula hub longitudinally in place relative to one another, as well as an unlocked arrangement in which the needle hub and the cannula hub may be moved toward and/or away from one another, enabling the needle to move through the cannula. Methods for obtaining samples from a body of a subject are also disclosed.

Abstract: A guidewire retention clip is provided to prevent the accidental, complete insertion of a guidewire into a patient during various procedures. As provided herein, the guidewire retention clip may include a body having a portion configured to hold a guidewire; a sensor associated with the body configured to detect movement of the guidewire to and from the body; and an audio and/or visual indicator arranged on the body, wherein the audio and/or visual indicator is triggered when the sensor detects movement of the guidewire. Methods of using the guidewire retention clip are also provided.

Abstract: A method of analyzing vaginal fluid includes collecting vaginal fluid in a vaginal fluid collecting system and transporting the collected vaginal fluid to a location for analysis. The analysis can be stored in and retrieved from a secure cloud storage data base.

Abstract: The invention provides methods and kits for detecting, screening, quantifying or localizing the etiology for reduced or impaired cranial nerve function or conduction; localizing a central nervous system lesion; detecting, diagnosing or screening for increased intracranial pressure, pressure or disruption of central nervous system physiology as seen with concussion; or detecting, diagnosing, monitoring progression of or screening for a disease or condition featuring increased intracranial pressure or concussion by tracking eye movement of the subject. The invention also provides methods and kits useful for detecting, screening for or quantitating disconjugate gaze or strabismus, useful for diagnosing a disease characterized by disconjugate gaze or strabismus in a subject, useful for detecting, monitoring progression of or screening for a disease or condition characterized by disconjugate gaze or strabismus in a subject or useful for quantitating the extent of disconjugate gaze or strabismus.

Abstract: The invention relates to a system of analyzing and quantifying a user's posture and gait, characterized in that it includes a pair 10 of soles 11, 12 each provided with an electronic box 100, 101, 102, each box comprising: an inertial platform, a data processing module 120, 121, 122, a data storage module 130, 131, 132, a means of communication 140, 141, 142, a power source 150.

Abstract: The present invention relates to a biopsy assembly for obtaining a tissue sample, comprising an outer tubular cannula provided with an oblique distal tip, and a stylet adapted to be disposed axially within said cannula and having an oblique distal tip. The stylet is provided with a recess arranged along a side of the stylet which is adapted to receive the tissue sample. The assembly further comprises a housing for guiding and manipulating the proximal ends of the cannula and the stylet and is provided with a rotating member configured to rotate the stylet or cannula around a common axis, such that the cannula and the stylet are rotated relative to one another. The rotating member is configured to rotate the stylet and cannula relative to one another prior to tissue sampling, such that a most distal edge of the oblique distal tip of said cannula is arranged at the same side as the recess when the tissue sampling is performed.

Abstract: A berg balance testing apparatus includes: a floor frame that is a stage on which the examinee takes movements; a plurality of first sensors that is disposed in sections divided to have a predetermined area on the floor frame and senses positions of the feet of the examinee; a second sensor that is disposed at a predetermined distance from the first sensors and senses movements of the examinee; a controller that performs a berg balance test on movements of the examinee on the basis of information sensed and transmitted by the first sensors and the second sensor; and a display that receives berg balance test guide and test result information from the controller and outputs the information through images.

Abstract: In some embodiments, there is provide a method of analysing a bone fracture, comprising; stabilizing a bone having a fracture including a first support point located distal of the fracture and a second support point located proximal of the fracture; applying a force to an area of the bone having the fracture to cause a displacement of the fracture; imaging the bone during the application of force thereto; and comparing the image of the bone during the application of force to an image of the bone without the application of force to determine the state of the fracture.

Abstract: Systems, devices, and methods are described for neuromonitoring. A minimum stimulus signal required to elicit a threshold neuromuscular response is determined by delivery of stimulus signals to tissue and detection of neuromuscular responses in muscle tissue. The strength of the delivered stimulus signals is varied, for example by adjusting the current amplitude or pulse width of the signals, and muscle responses are measure, for example by detecting EMG signals. The delivered stimuli and corresponding responses are then used to determine a stimulation threshold. The stimulation threshold may be used to indicate at least one of nerve proximity and pedicle integrity.

Abstract: The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

Abstract: In-vivo fluid monitoring devices and methods are disclosed herein. An example device is configured for patients which monitors increases and decreases of fluid retention in patients with various clinical conditions such as heart and renal failure pre-operation and post operation thus allowing physicians to more accurately detect said fluid retention gains through a mechanism directly or indirectly connected to circulatory stocking which act as a conduit to detect said fluid changes through skin electrolysis and alterations respective to fluid changes directly corresponding with galvanic skin response measurement changes.

Abstract: A biopsy sampling device comprises a handle with a flexible cannula extending from the handle. The flexible cannula includes: an inner catheter, which defines an opening in a lateral wall surface thereof, and further defines a central lumen in fluid communication with the opening; an outer catheter positioned around and moveable relative to the inner catheter; and a cutting element positioned at a distal end of the outer catheter. The flexible cannula is configured such that a vacuum can be applied through the central lumen of the inner catheter to create a suction that draws a piece of tissue into the opening defined in the lateral wall surface of the inner catheter. The handle is configured to move the inner catheter relative to the outer catheter, such that the cutting element shears and severs the piece of tissue that has been drawn into the opening.

Abstract: Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.