Abstract: A transcatheter valve prosthesis includes a stent having a compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve and a prosthetic valve component disposed within and secured to the stent. A compartment is coupled to the stent, and a filtered opening into the compartment is configured to permit blood flow there-through and to trap emboli in the blood flow within the compartment.

Abstract: A stent and method for treating an end of a pre-woven stent is provided. The method includes providing a pre-woven stent including a plurality of sharp ends. A pair of wire portions that extend in opposite helical directions around the stent are bent and woven into the stent to define a pair of overlapping crown portions. When the wires are woven into the stent a double weave portion of the stent is defined. The wires can be cut to define tail portions that are removed from the stent, leaving a single crown portion. The sharp ends can be alternatively treated by curving the ends to define rounded looped ends.

Abstract: A medical device configured for placement in a blood vessel, in which an elastic tube extends between first and second expandable anchoring stents. The elastic tube is constructed of a resilient material that deflects outward in response to increased blood pressure of a heart beat and that moves back inward as the blood pressure drops, thereby aiding the heart's pumping action.

Abstract: A percutaneous heart valve for deployment within a body cavity is described. The percutaneous heart valve includes an expandable frame having a plurality of cells adapted for allowing the frame to expand and collapse. A one-way valve is positioned within the expandable frame. The frame includes a proximal anchoring portion and a distal anchoring portion. The distal anchoring portion includes a plurality of distal anchors, each distal anchor having at least a portion positioned radially outwardly from the frame and extending in a direction that is substantially parallel with a longitudinal axis. The distal anchors preferably bend radially outwardly before bending to extend toward the proximal anchoring portion. Radial expansion of the frame causes the proximal and distal anchoring portions to move closer together for capturing body tissue therebetween, thereby anchoring the percutaneous heart valve to the body tissue.

Abstract: A stent that includes a stent body and one or more weld joints, wherein the weld joints include a radiopaque material, and a method of making a stent that includes using a radiopaque filler material in a welding process.

Abstract: An orthopedic prosthesis for use in a hip replacement surgery. The orthopedic prosthesis includes an elongated stem component that has a proximal body, a neck extending superiorly and medially from the proximal body and a tapered stem extending inferiorly from the proximal body. An anchor is positioned on the neck and is configured to be engaged by a surgical instrument. A system for use in assembling the orthopedic prosthesis and a method of assembly are also disclosed.

Abstract: A stent in the form of a generally tubular body has multiple annularly expandable serpentine elements. The serpentine elements have arcs at the first and second element ends which point in the axial direction of the stent. Annularly expandable serpentine elements which follow one another in the axial direction are connected to one another via connectors which are arranged at the ends of the adjacent elements. The connectors extend in the circumferential direction of the stent in the non-expanded state of the stent and have a curvature in the circumferential direction. In the expanded state of the stent, the curvature is so great in the circumferential direction that the connectors project radially outward beyond the circumference of the serpentine elements.

Abstract: A valve replacement implant may include an expandable anchor member having a proximal end and a distal end, the anchor member being actuatable between a delivery configuration and a deployed configuration. A plurality of locking mechanisms may be configured to secure the anchor member in the deployed configuration. Each locking mechanism may include an axially movable post including a leg portion extending inwardly therefrom, and a receiving portion fixed to the anchor member, the receiving portion being configured to slidably receive the post. A plurality of valve leaflets may be disposed within a central lumen of the anchor member, the plurality of valve leaflets being secured to the leg portions of the plurality of locking mechanisms. The plurality of locking mechanisms may be releasably attached to a delivery device.

Abstract: A device for treating acid reflux comprising a sleeve configured and dimensioned for insertion into the esophagus of the patient, the sleeve having a proximal portion, a distal portion and an intermediate portion between the distal and proximal portions. The sleeve includes a an inner member applying a radial force on the sleeve for securement within the esophagus, and a skirt connected to the sleeve to block acid backup from the stomach while not inhibiting passage of food into the stomach.

Abstract: A talar implant system comprises a body. The body includes a bone contact surface and an articulation surface located opposite the bone contact surface. The body defines at least one angled fastener hole extending therethrough from the articulation surface to the bone contact surface along a longitudinal axis. The articulation surface is configured to mimic articulation of the talar dome. A fastener is sized and configured to be received within the at least one fastener hole at a first angle with respect to the longitudinal axis of the fastener hole. A fastener cap is sized and configured to be received within a proximal end of the at least one fastener hole. The fastener cap couples the body to the fastener.

Abstract: A prosthetic joint (100) comprises a first component (110) having a first interface portion (111). The prosthetic joint (100) further comprises a second component (120) having a second interface portion (121) with a textured surface (122) to interface with the first interface portion (111) and form a skeletal joint. The textured surface (122) can include a plurality of concave features (123). Each or the concave features (123) can be configured to compress a lubricant (140) to facilitate hydrodynamic lubrication between the first and second interface portions (111, 121) to minimize wear between the first interface portion (111) and the second interface portion (121) of the prosthetic joint (100).

Abstract: A modular humeral prosthesis suitable for implant in a humeral seating of a humerus comprises an articulation component, a distal joint element able to be inserted into said humeral seating along an insertion axis, and an adapter body provided with a support positionable in the humeral seating and that has a coupling seating to connect said articulation component and provided with a connection unit inserted into said support to connect said distal joint element to said adapter body in a releasable manner. The connection unit comprises a clamping element associated in a selectively releasable manner to the distal joint element and the support has a through coupling seating configured to receive and position said clamping element inside it, and also configured to allow the insertion and extraction of said distal joint element through said support without removing said support from the humeral seating.

Abstract: Prostheses that address stress shielding are disclosed. For instance, a knee prosthesis includes a monolithic femoral component having medial and lateral condylar elements for confronting and engaging a natural tibia or a bearing member of a tibial component, an intercondylar notch between the condylar elements for confronting and engaging a natural patella or a patellar component, and an anterior flange extending proximally from the medial and lateral condylar elements and the intercondylar notch. The femoral component defines a bone-facing surface and a bearing surface, the bearing surface including medial and lateral condylar articular surfaces defined by the medial and lateral condylar elements, respectively, and an intercondylar articular surface defined by the intercondylar notch. A slot extends through the femoral component from the bearing surface to the bone-facing surface, the slot starting at an edge of the femoral component and ending at a location within the anterior flange.

Abstract: A prosthetic heart valve includes a collapsible stent extending from an inflow end to an outflow end, and a cuff having an inflow end an outflow end. The stent includes first and second circumferential rows of cells defined by first and second pluralities of struts, respectively. The second circumferential row is positioned closer to the outflow end of the stent than the first circumferential row. At least one cell in the second circumferential row includes by a first strut opposed to a fourth strut and a second strut opposed to a third strut. A bridging feature in at least one cell in the second circumferential row includes first and second supplemental struts extending across an intermediate portion of the cell. The outflow end of the cuff is coupled to the stent along the bridging feature.

Abstract: In one embodiment, a prosthetic component includes a plurality of fixation pads coupled to a body portion. The fixation pads may be formed of a first material suitable for attachment to bone, and the body portion may be formed of a second material different from the first material and suitable to provide a bearing surface for a joint.

Abstract: A glass, glass-ceramic, or ceramic bead is described, with an internal porous scaffold microstructure that is surrounded by an amorphous shield. The shield serves to protect the internal porous microstructure of the shield while increasing the overall strength of the porous microstructure and improve the flowability of the beads either by themselves or in devices such as biologically degradable putty that would be used in bone or soft tissue augmentation or regeneration. The open porosity present inside the bead will allow for enhanced degradability in-vivo as compared to solid particles or spheres and also promote the growth of tissues including but not limited to all types of bone, soft tissue, blood vessels, and nerves.

Abstract: A process and system for performing orthopedic surgery to create a series of channels with a subject's bone to allow a reduced pressure system to be applied directly to the bone-implant interface to enhance bone healing is provided. The process for to promote healing of a bone of a subject includes creating a three-dimensional model of the bone; preoperatively planning a location of an implant relative to the model; creating a plan for the location of precision channels that reach the bone-implant interface based on the model and the implant; resurfacing the bone to fit the implant into or onto the bone based on the preoperative plan; and milling the precision channels into the bone in the location to promote healing of the bone and/or bone implant interface; and applying a pressure reduction system at the bone-implant interface to promote bone healing.

Abstract: An endoprosthesis for knee joint arthrodesis having a femur portion including a femur attachment structure; a tibia portion including a tibia attachment structure; a coupling section formed on the femur portion and a coupling section formed on the tibia portion. The coupling sections are pivotably connected to one another about a prosthesis pivot axis that extends in the installed position of the endoprosthesis horizontally from medial to lateral. A locking element is moveable between locking and release positions. In the locking position the locking element rigidly locks the coupling sections in a predefinable pivot position. In the release position the coupling sections are pivotable relative to one another about the prosthesis pivot axis. A retaining and return means and an unlocking mechanism are provided. The retaining means forces the locking element into the locking position. The unlocking mechanism moves the locking element into the release position.

Abstract: An orthopedic joint prosthesis may include a first component, a bearing component, and a third component. The first component has a base and a keel protruding from the base to extend into a first bone. The keel's longitudinal axis is offset from a geometric center of the base. The base has a first articular surface and the bearing component has a second articular surface shaped to articulate with the first articular surface. A feature unitary with the first component reversibly attaches to the bearing component. The bearing component has a third articular surface shaped to articulate with a fourth articular surface on the third component. A distraction feature of the bearing component is shaped to provide alignment and/or distraction between the first articular surface and the fourth articular surface during insertion of the bearing component into a joint space between the first and second bones.

Abstract: A glenosphere includes a body, a first surface, a second surface, a cavity defined within the body, and a plurality of channels. The body defines a central axis passing through the body. The first surface includes a first rim and a second rim. The first rim is positioned radially outward from the second rim relative to the central axis. The second surface extends from the first rim of the first surface. The second surface has a convex shape. The cavity has a perimeter defined by the second rim and is configured to receive an attachment structure attachable to a bone. The plurality of channels extend from the first surface through the body to the second surface. Each channel defines a first opening positioned on the first surface between the first rim and the second rim and defines a second opening positioned on the second surface. Each channel is configured to receive a bone fixation member configured to secure the glenosphere to the bone.