Patents Examined by Melissa A Mercier
  • Transdermal pharmaceutical preparation containing active substance combinations, for treating Parkinson's disease
    Patent number: 8980308
    Abstract: The transdermal pharmaceutical preparations for the treatment of Parkinson's disease contain a combination of at least two active substances selected from the following groups of active substances: dopamine agonists and L-dopa, monoamine oxidase inhibitors, anticholinergics, NMDA-receptor antagonists, sympathomimetics; at least two of the said active substances being members of different active substance groups.
    Type: Grant
    Filed: August 14, 2004
    Date of Patent: March 17, 2015
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Michael Horstmann, Frank Theobald
  • Barrel-shaped vaginal ring
    Patent number: 8980304
    Abstract: The present invention relates to annular intravaginal devices comprising an aperture, methods of making, and uses thereof. The annular devices comprise an aperture extending into the device, the aperture having: (a) an interior diameter, and (b) an exterior entry diameter, wherein the exterior entry diameter of the aperture is less than the interior diameter of the aperture.
    Type: Grant
    Filed: August 18, 2011
    Date of Patent: March 17, 2015
    Assignee: Teva Women's Health, Inc.
    Inventor: Jiaxiang Tsao
  • Personal care compositions and methods of making same
    Patent number: 8980239
    Abstract: The present invention relates to a personal care composition and methods of using the same, the composition including an anionic surfactant, a cationic conditioning polymer, and a silicone emulsion wherein a total content of a cyclic polysiloxane having a general formula: is present in the silicone emulsion in an amount less than 2.5 wt % based on the total weight of all polysiloxanes, R is a substituted or unsubstituted C1 to C10 alkyl or aryl, wherein m is 4 or 5, wherein the composition forms coacervate particles upon dilution with water, and wherein a percentage of the coacervate particles with a floc size of greater than about 20 micron is from about 1% to about 60% upon dilution with water.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: March 17, 2015
    Assignee: The Procter & Gamble Company
    Inventors: James Anthony Staudigel, Eric Scott Johnson, Sean Michael Renock, Marjorie Mossman Peffly, Kelly Rose Kroger Lyons
  • Method for drying biomaterials
    Patent number: 8974778
    Abstract: The present invention provides a means to concentrate, dry and formulate biomaterials such as polysaccharides, gums and related biopolymers, and microorganisms such as cells, spores, and the like from dilute solutions using spent germ and other oil bearing residues. In addition, the spent germ can serve as a carrier for such biomaterials. The sorbed materials are useful in animal feeds.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: March 10, 2015
    Assignee: Grain Processing Corporation
    Inventor: Sarjit Johal
  • Highly wettable, water dispersible, granules including two pesticides
    Patent number: 8968757
    Abstract: The present disclosure relates to water dispersible granular pesticide compositions, and methods of making and using the compositions. The pesticide compositions include an inner layer including a first pesticide coated on to a substrate, and an outer layer comprising a second pesticide coated on the inner layer. The outer layer increases the water dispersibility of the granular composition, and protects the first pesticide against hydrolysis and photolysis.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: March 3, 2015
    Assignee: Ecolab USA Inc.
    Inventors: Victor F. Man, Yvonne M. Killeen, Susan M. Viall
  • Powdery cosmetic composition
    Patent number: 8956633
    Abstract: The present invention relates to a cosmetic composition comprising a pulverulent phase comprising at least one composite powder including titanium dioxide and magnesium oxide. The cosmetic composition according to the present invention is at least comparable in terms of cosmetic effects with conventional cosmetic compositions comprising a conventional composite powder including titanium dioxide and zinc oxide. Therefore, the cosmetic composition is free of any potential problems which may be caused by zinc oxide which is commonly used in conventional cosmetic compositions.
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: February 17, 2015
    Assignee: L'Oreal
    Inventor: Takehiko Kasai
  • Fulvestrant nanosphere/microsphere and preparative method and use thereof
    Patent number: 8956659
    Abstract: Fulvestrant nanosphere/microsphere and preparation method and use thereof are provided in the present invention. The carrier material of the fulvestrant nanosphere/microsphere is methoxy ended polyethylene glycol-polylactic acid block copolymer. The nanosphere/microsphere is prepared by solvent-nonsolvent method, in-liquid drying method and/or spray drying method, and has the features of high drug loading and high encapsulation efficiency, controllable release of medicine and no irritant to application site or blood vessel. The fulvestrant nanosphere/microsphere can be used to treat metastatic advanced breast cancer in post-menopausal woman.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: February 17, 2015
    Assignee: Xi'an Libang Pharmaceutical Technology Co., Ltd.
    Inventors: Renle Hu, Jiucheng Wang, Yaqi Jiao, Hua Liang, Duohao Ding
  • Use of selective estrogen receptor modulator for joint fusion and other repair or healing of connective tissue
    Patent number: 8933028
    Abstract: Methods for facilitating joint immobilization or fusion using selective estrogen receptor modulator (SERM) such as raloxifene are disclosed. The SERM may be administered systemically or locally. In conjunction with SERM, other therapeutic agents such as calcium, vitamin D, bone morphogenetic protein may be administered simultaneously. The method can similarly be applied to facilitate bone repair, bone healing, and connective tissue healing processes in a patient.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: January 13, 2015
    Inventor: John G. Stark
  • Rifaximin complexes
    Patent number: 8916193
    Abstract: There is provided a complex comprising rifaximin and a complexing agent, wherein the complexing agent is a polyvinyl pyrrolidone (PVP) or a cyclodextrin. There is also provided a process for preparing the complex, a pharmaceutical composition including the complex, and therapeutic uses of the complex.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: December 23, 2014
    Assignee: Cipla Limited
    Inventors: Maruti Ganpati Ghagare, Sunilkumar Parasnath Saroj, Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan
  • Bio-Remodable Bone Augmentation device and method
    Patent number: 8900617
    Abstract: A bio-remodable augmentation device including an implantable member configured for maintaining space in a bone defect. The implantable member is formed from a bio-remodable composite having structural properties so as to aid in the generation of new bone tissue and eventually be reabsorbed in the newly formed bone tissue. This structural and bio-remodable implant reduces, if not eliminates, the need to remove the implantable member from the patient once new bone tissue is formed. A kit including the implantable devices and bone growth material is disclosed. Methods of use are also disclosed.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: December 2, 2014
    Assignee: Warsaw Orthopedic, Inc.
    Inventor: William F. McKay
  • Diethylstilbestrol dosage form and methods of treatment using thereof
    Patent number: 8900634
    Abstract: Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, particularly diethylstilbestrol and pharmaceutically acceptable salts thereof to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: December 2, 2014
    Assignee: NAL Pharmaceuticals, Ltd.
    Inventors: Je Phil Ryoo, Chun Kwong Chu, Zheng Wang, Diana Shu-Lian Chow, Roland A. Ako
  • Hard capsule and method for producing same
    Patent number: 8900628
    Abstract: This invention provides a hard capsule that has excellent stability even when filled with a solvent for dissolving poorly soluble drugs, and that also achieves reduction in disintegration time, thereby ensuring excellent solubility. Specifically, the hard capsule of the present invention has a film comprising: (A) a polymer or copolymer obtained by polymerizing or copolymerizing, in the presence of polyvinyl alcohol and/or a derivative thereof, at least one polymerizable vinyl monomer represented by Formula (1): H2C?C(R1)—COOR2??(1) wherein R1 represents hydrogen or methyl, and R2 represents hydrogen or alkyl having 1 to 4 carbon atoms; and (B) native gellan gum.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: December 2, 2014
    Assignee: Nisshin Kasei Co., Ltd.
    Inventors: Toshiaki Moriuchi, Akane Kojo, Yusuke Hayashi, Hiroyuki Yoshino
  • Food preservation compositions and methods
    Patent number: 8895044
    Abstract: A method of protecting food or delaying the onset of food spoilage said method comprising applying a protective bioactive composition to the food or the packing or packaging in which the food is stored.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: November 25, 2014
    Assignee: Sciessent, LLC
    Inventor: Joseph J. Crudden
  • Circulation of components during homogenization of emulsions
    Patent number: 8895629
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves circulation of emulsion components between a first container and a second container via a homogenizer and/or via a microfluidization device. Usefully, all of the emulsion components from the first container are emptied before being returned.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: November 25, 2014
    Assignee: Novartis AG
    Inventors: Harald Rueckl, Hanno Scheffczik, Barbara Santry
  • Personal care compositions with acidified pectins
    Patent number: 8895513
    Abstract: Personal care compositions are provided that include acidified pectins at a concentration of about 2 to about 5% by weight. The acidified pectin includes a low ester pectin with a degree of esterification of about 30 to about 50 and a pH of about 2 to about 4. Desirably, the personal care composition is characterized as a viscous, fluid gel. Also provided are methods for preparing personal care compositions and methods for the use of personal care formulations.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: November 25, 2014
    Assignee: CP Kelco ApS
    Inventors: Jens Eskil Trudsoe, Helle Bech Olsen
  • Cosmetic compositions comprising latex film formers
    Patent number: 8889108
    Abstract: Disclosed are cosmetic compositions comprising at least one latex-film former chosen from at least one acrylate copolymer and derivatives thereof, and at least one coalescent and/or plasticizer.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: November 18, 2014
    Assignee: L'Oreal
    Inventors: Chunhua Li, Hy Si Bui, Jean-Thierry Simonnet, Anne Wagner, Ruth Josie Donat
  • Intraocular encapsulation of oxygenic bacteria
    Patent number: 8883189
    Abstract: Exemplary embodiments comprise an implantable ophthalmic device comprising at least one shell encapsulating oxygenic bacteria and growth medium and designed to increase the oxygen partial pressure in an oxygen-deprived structure of, or space within, an eye. Exemplary embodiments may be used therapeutically to treat ischemic retinopathies in situ and thereby prevent damage, for example, retinal damage.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: November 11, 2014
    Assignee: The Regents of the University of Colorado, a Body Corporate
    Inventor: Jeffrey Olson
  • Medicated patch
    Patent number: 8871249
    Abstract: Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: October 28, 2014
    Assignee: Hisamitso Pharmaceutical Co., Inc.
    Inventors: Naoki Yamamoto, Kumi Morimoto, Akio Takeuchi, Kenji Ishigaki
  • Methods for producing vaccine adjuvants
    Patent number: 8871816
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) microfluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: October 28, 2014
    Assignee: Novartis AG
    Inventors: Harald Rueckl, Hanno Scheffczik, Barbara Santry
  • Methods and compositions for controlled delivery of phytochemical agents
    Patent number: 8858995
    Abstract: Compositions are provided that comprises a biocompatible polymeric matrix incorporating an effective amount of a phytochemical agent, a combination of phytochemical agents, or a phytochemical agent and one or more additional therapeutic agents. Methods of treating a cancer using the compositions are further provided.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: October 14, 2014
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Ramesh C. Gupta, Manicka V. Vadhanam, Farrukh Aqil