Patents Examined by Melissa A Mercier
  • Adhesive skin patch containing serotonin receptor antagonist drug
    Patent number: 9205060
    Abstract: Provided is a transdermal absorption-type patch containing a serotonin receptor antagonist, which has a short transdermal absorption delay time (lag time), and in which the maximum transdermal permeation rate of the drug can be reached within a short time and the drug can disappear from circulating blood rapidly. That is, provided is a patch containing a serotonin receptor antagonist, wherein the patch contains an adhesive layer comprising a non-functional acrylic adhesive, a water-soluble organic amine, a fatty acid ester, and a serotonin receptor antagonist such as granisetron as an active ingredient.
    Type: Grant
    Filed: July 4, 2012
    Date of Patent: December 8, 2015
    Assignee: Teikoku Seiyaku Co., Ltd.
    Inventors: Takashi Kamakura, Daiki Takano
  • Free-standing biodegradable patch
    Patent number: 9192698
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: November 24, 2015
    Assignee: BioInspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Polyester implantable medical device with controlled in vivo biodegradability
    Patent number: 9186440
    Abstract: This invention relates to blends of high, optionally medium, and low molecular weight polyesters where at least the low molecular weight polyester is substituted with an acidic moiety, the biodegradation of the blends being controllable by selection of the mean molecular weigh of each fraction, the quantity of each fraction in the blend and the amount and pKa of the acidic moiety(ies).
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: November 17, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Yunbing Wang
  • Compositions and devices incorporating water-insoluble therapeutic agents and methods of the use thereof
    Patent number: 9180226
    Abstract: Various aspects of the present invention provide compositions and implantable devices including a water-insoluble therapeutic agent solubilized in a matrix of a gallate-containing compound. Other aspects provide methods of manufacturing and using such compositions and devices.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: November 10, 2015
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: John Jackson, Lindsay Stuart Machan, Kevin Letchford
  • Method and composition for enhancing milk production and milk component concentrations
    Patent number: 9179694
    Abstract: A method of feeding a ruminant that entails providing a feed that comprises sugar alcohol and at least one additional feed component, where the feed is free of rumen-protected fatty acid or comprises less than 10 weight percent rumen-protected fatty acid, based on the total weight of the feed and further entails orally supplying the feed to the ruminant during a pre-partum period when the ruminant is pregnant, where the ruminant ingests the feed and sugar alcohol during the pre-partum period.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: November 10, 2015
    Assignee: PURINA ANIMAL NUTRITION LLC
    Inventors: Paul A. Porter, Cindie M. Luhman
  • Process for treating straightened keratin fibres
    Patent number: 9180086
    Abstract: The present invention relates to a process for treating straightened keratin fibers, in which a composition comprising at least one carboxylic acid in its acid or salified form, at a concentration of greater than or equal to 2%, and at least one non-cellulosic polymer and/or at least one fatty substance, the pH ranging from 3 to 8, is applied to the straightened keratin fibers.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: November 10, 2015
    Assignee: L'OREAL
    Inventors: Julien Cabourg, Gregory Plos, Laetitia Feuillette
  • Intravaginal delivery system
    Patent number: 9168303
    Abstract: The present invention in general relates to an intravaginal delivery system as well as uses thereof and methods for manufacturing and use of the same. In particular the present invention relates to an intravaginal delivery system for the controlled release of one or more organic acids, such as lactic acid; said intravaginal delivery system being characterized in that it comprises a combination of ethylene vinyl acetate (EVA) copolymers and carboxylic polymers, such as for example methacrylic acid-methacrylic ester copolymers.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: October 27, 2015
    Assignee: Universiteit Gent
    Inventors: Jean Paul Remon, Chris Vervaet, Hans Verstraelen, Marleen Temmerman
  • Use of N-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-3-amine and related compounds
    Patent number: 9161894
    Abstract: This invention provides methods for treating diseases or conditions wherein the inhibition of Kit protein kinase may be beneficial, using pharmaceutical or cosmetic compositions comprising N-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-3-amine (FPL-62064) and related compounds. This invention also relates to the treatment of skin disorders, such as hyperpigmentation and cutaneous mastocytosis, and to cosmetic uses such as skin lightening.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: October 20, 2015
    Assignee: NPHARMAKON, LLC
    Inventors: Dmitri Rebatchouk, Felix Sheinerman
  • Transdermal drug delivery device including an occlusive backing
    Patent number: 9155712
    Abstract: A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: October 13, 2015
    Assignee: NOVEN PHARMACEUTICALS, INC.
    Inventors: David Kanios, Juan A. Mantelle, Viet Nguyen
  • Razor comprising a molded shaving aid composition comprising a pyrithione source
    Patent number: 9119796
    Abstract: Razors comprising a shaving aid comprising a soap base and a pyrithione source.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: September 1, 2015
    Assignee: The Gillette Company
    Inventors: Jason Edward Cook, Chunpeng Jiang, Brian Joseph Limberg, Edward Dewey Smith, III, Juan Wang, Xiaoyong Wang
  • Dosage form for insertion into the mouth
    Patent number: 9119776
    Abstract: Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: September 1, 2015
    Assignee: NAL Pharmaceuticals, Ltd.
    Inventors: Je Phil Ryoo, Chun Kwong Chu, Zheng Wang
  • Dosage form for insertion into the mouth
    Patent number: 9114073
    Abstract: Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: August 25, 2015
    Assignee: NAL Pharmaceuticals, Ltd.
    Inventors: Je Phil Ryoo, Chun Kwong Chu, Zheng Wang
  • Method for drying biomaterials
    Patent number: 9113646
    Abstract: The present invention provides a means to concentrate, dry and formulate biomaterials such as polysaccharides, gums and related biopolymers, and microorganisms such as cells, spores, and the like from dilute solutions using spent germ and other oil bearing residues. In addition, the spent germ can serve as a carrier for such biomaterials. The sorbed materials are useful in animal feeds.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: August 25, 2015
    Assignee: Grain Processing Corporation
    Inventor: Sarjit Johal
  • Dosage form for insertion into the mouth
    Patent number: 9114074
    Abstract: Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: August 25, 2015
    Assignee: NAL Pharmaceuticals, Ltd.
    Inventors: Je Phil Ryoo, Chun Kwong Chu, Zheng Wang
  • Dosage form for insertion into the mouth
    Patent number: 9114075
    Abstract: Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: August 25, 2015
    Assignee: NAL Pharmaceuticals, Ltd.
    Inventors: Je Phil Ryoo, Chun Kwong Chu, Zheng Wang
  • Methods and compositions for self-regulated release of active pharmaceutical ingredient
    Patent number: 9101636
    Abstract: An abuse deterrent pharmaceutical composition including a pharmaceutically active ingredient; an acid soluble ingredient; and a buffering ingredient; wherein the acid soluble ingredient and the buffering ingredient retard release of the active pharmaceutical ingredient when the composition is ingested in excess of an intended dosage.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: August 11, 2015
    Assignee: Acura Pharmaceuticals, Inc.
    Inventors: Albert W. Brzeczko, R. Gary Hollenbeck
  • Compositions with modulating agents
    Patent number: 9101662
    Abstract: The present invention relates to a waterless composition and foam as a vehicle in which an active pharmaceutical or cosmetic agent, when added is stable or stabilized by or its destabilization is impeded by the presence of a modulating agent. The pharmaceutical or cosmetic composition and foam, includes: a waterless solvent, a modulating agent and one or more active pharmaceutical or cosmetic agents. The present invention also relates to a method of treatment administering the waterless composition and foam.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: August 11, 2015
    Assignee: Foamix Pharmaceuticals Ltd.
    Inventors: Dov Tamarkin, Meir Eini, Doron Friedman, Tal Berman, David Schuz
  • Suspension compositions of physiologically active phenolic compounds and methods of making and using the same
    Patent number: 9084726
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: July 21, 2015
    Assignee: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • Hypoxia-responsive nanoparticle for therapy and imaging of hypoxia-involving diseases
    Patent number: 9084806
    Abstract: The present invention relates to an amphiphilic polymer whose property and structure can change under hypoxic conditions, and to nanoparticles formed by self-assembly of the amphiphilic polymer. The hypoxia-responsive nanoparticles according to the present invention release a drug selectively under hypoxic conditions. Thus, the nanoparticles can be used for the selective diagnosis and treatment for diseases that are accompanied by hypoxia. Particularly, the nanoparticles can release a drug only to a targeted tumor in cancer therapy, and thus have minimized side effects and maximized therapeutic effects.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: July 21, 2015
    Assignee: Research & Business Foundation Sungkyunkwan University
    Inventor: Jae Hyung Park
  • Intravaginal devices for controlled delivery of lubricants
    Patent number: 9078813
    Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: July 14, 2015
    Assignee: THE UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright