Abstract: An apparatus includes a housing, a catheter, and an actuator. The housing has a first port and a second port that is coupleable to an indwelling vascular access device. The catheter is at least partially disposed in the housing such that the first port of the housing receives a proximal end portion of the catheter. The actuator is partially disposed in the housing to selectively engage a portion of the catheter in the housing. The actuator is configured to be rotated an angular distance relative to the housing to move a distal end portion of the catheter a linear distance from a first position inside the housing, to a second position in which the catheter extends through the second port and distal to the indwelling vascular access device when the second port is coupled thereto. The linear distance is greater than the angular distance.

Abstract: A tuning pin for a steering actuator comprising a head portion proximate a proximal end of the tuning pin, the head portion comprising an anti-rotation element, a body portion distal the head portion, the body portion comprising a through hole, and a tip portion distal the body portion and proximate a distal end of the tuning pin, the tuning pin configured to couple with a pin block in the steering actuator. A system comprising a catheter, and a steering actuator comprising a tuning pin, the tuning pin comprising a head portion proximate a proximal end of the tuning pin, the head portion comprises an anti-rotation element, a body portion distal the head portion, where the body portion comprises a through hole, and a tip portion distal the body portion and proximate a distal end of the tuning pin, wherein the tuning pin is configured to couple with a pin block.

Abstract: Compositions, systems, devices, and methods for performing precise chemical treatment of tissues are disclosed. Systems, devices, and methods for administering a chemical agent to one or more a precise regions within a tissue mass are disclosed. Compositions, systems, devices, and methods for treating targeted regions within a tissue mass are disclosed. Systems, devices, and methods for identifying, localizing, monitoring neural traffic in the vicinity of, quantifying neural traffic in the vicinity of, and mapping neural traffic near targeted regions within a tissue mass are disclosed.

Abstract: A medical device includes a catheter, which includes a first lumen for injection of a first volume of a treatment solution, the first lumen opening out at the distal end of the catheter; and a junction element extending the first lumen at the end of the catheter including a diameter at the distal end thereof less than the diameter of the catheter.

Abstract: Distal access aspiration guide catheter system and methods for delivering implantable devices, catheters, or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens are described. A Distal access aspiration guide catheter having a proximal, medial, and distal possessing high flexibility, high resistance to kinking and a large lumen to wall thickness ratio.

Abstract: Needle assemblies and related methods in which a valve opener is used to push into a valve to open one or more slits on the valve to open the valve. The needle assemblies each includes a needle hub with a needle, a catheter tube with a catheter hub and the valve and valve opener positioned in the interior cavity of the catheter hub. The valve can have a valve skirt and a nose section of the valve opener can locate therein. One or more reliefs can be provided with the valve opener so that an elbow or diagonal section on a needle guard can project from a holding space within the valve opener through the relief.

Abstract: A unilateral driving mechanism for a portable infusion system is provided. The unilateral driving mechanism comprises an actuator (1), a swinging part (2), gears (4), blockers (5), a compression spring (6), a rod (7), a reservoir (8), a plunger (9) and a control circuit. One end of the rod (7) is connected with the gears (4), the other end of the rod (7) is connected with the plunger (9), and one lower limb of the swinging part (2) is connected with the spring (6). The unilateral driving mechanism for a portable infusion system has advantages of compact structure, small volume, low power consumption, low cost, high precision and convenience in use.

Abstract: A method for facilitating milk extraction from a female breast may involve applying a breast contacting portion of a breast pump system to a breast, activating the breast pump system to administer multiple breast pumping cycles, and applying vibrations to the breast during at least a portion of each of the breast pumping cycles, using a vibration device. A vibration generating device may be a component of a breast pump system, an added attachment on a breast pump system or a separate component that works in conjunction with a breast pump system.

Abstract: A breast pump is disclosed. According to an aspect of the present invention, there is provided a breast pump comprising a contact housing comprising a protruding part configured to correspond to a mother's nipple and extend toward the front and a breast milk outlet hole formed at the protruding part; a cap connector coupled to cover an end of the protruding part to form a first inner space between the end of the protruding part and itself and comprising a breast milk outlet tube linked with the breast milk outlet hole and the first inner space; a funnel connector on the cap connector to form a second inner space; a storage housing comprising a coupling hole to correspond to the second inner space of the funnel connector and detachably coupled with the contact housing; a lid coupled to cover the second inner space of the funnel connector through the coupling hole of the storage housing; and a flow separation membrane configured to separate the space between the funnel connector and the lid.

Abstract: A needle safety device has an outer tube within which a syringe barrel from which a cannula extends is slideably receivable. A collar in the outer tube is moveable relative thereto and rotatably attachable to the distal end of the barrel. A force member biases the outer tube in a distal direction. A cannula shield able to receive the cannula therein is in the outer tube. The cannula shield is fixedly attached to a cap removably attached to the outer tube. A track is formed in the inner surface of the outer tube. A pin extending radially outwardly from the collar slidingly engages the track. In a pre-injection position, the cannula is entirely within the outer tube. In a full-insertion position, the cannula extends beyond the outer tube. In a locked position, the cannula is irreversibly retained entirely within the outer tube.

Abstract: Needle assemblies and related methods having a needle hub with a needle, a catheter tube with a catheter hub and having the needle extending through the catheter tube in a ready to use position. A valve is positioned in an interior cavity of the catheter hub, the valve having sections that can deflect in a distal direction and sections that can deflect in a proximal direction to open a fluid flow path through the valve. The valve can be deflected by a multi-piece valve opener.

Abstract: An insulin infusion set (IIS) device with one or more features designed to achieve longevity in a patients continuous subcutaneous insulin infusion (CSII) site viability. One exemplary feature is an adsorbent material configured to adsorb phenolic excipients (e.g., m-cresol or other preservatives) from the insulin formulation. The adsorbent material may be positioned along a fluid pathway specifically designed to increase and/or extend exposure between the insulin formulation and the adsorbent material. Another exemplary feature is a medicament configured to reduce the patients inflammation or slow the progression of the patients inflammatory response. Yet another exemplary feature is a diffusive catheter configured to deliver the insulin formulation in a diffuse manner.

Abstract: A pull wire attachment system for a minimally invasive medical instrument comprises an anchoring element, a steerable tube, and a pull wire assembly. The anchoring element comprises a hollow tube having a first outer diameter. The pull wire assembly comprising a pull wire having a proximal end and a distal end and a securing element coupled to the distal end. A portion of the pull wire is disposed within a groove having an open cross-sectional shape extending along a length of the steerable tube. The securing element includes a second outer diameter sized smaller than the first outer diameter. The securing element is coupled to the anchoring element to prevent proximal translation of the distal end of the pull wire along a longitudinal axis of the medical instrument past the anchoring element. A proximal end of the securing element is disposed distal to a distal end of the steerable tube.

Abstract: The disclosure relates to a syringe support for supporting an axial position of a syringe relative to a housing of an autoinjector. The syringe support includes a supporting beam arranged on the syringe support and biased radially inwards. The supporting beam is adapted to axially bias the syringe in a distal direction within the housing. The disclosure further relates to an autoinjector.

Abstract: A liquid transfer device is described. The liquid transfer device comprising a vial adapter comprising a puncturing cannula for puncturing an injection vial stopper, an IV spike and a substitute IV port holder for receiving a substitute IV port, and a flow control member port. The IV spike, the substitute IV port holder and the puncturing cannula are in flow communication with the flow control member port. The liquid transfer device comprising a flow control member sealingly inserted in the flow control member port. Rotation of the flow control member between a plurality of positions controls flow communication of the liquid transfer device, the positions comprising a mixing position for enabling flow communication between the IV spike and the puncturing cannula; and an administering position for enabling flow communication between the IV spike and the substitute IV port holder.

Abstract: A catheter tip is disclosed comprising a tip electrode comprising a ledge feature, and a center cavity and a manifold assembly comprising a fluid lumen manifold and a stop tube. The stop tube can be coupled to the fluid lumen manifold and configured to abut the ledge feature such that a distal end of the fluid lumen manifold extends a pre-determined distance into the center cavity of the tip electrode. The fluid lumen manifold can comprise a plurality of sideholes which can be sized and configured to distribute an irrigant to the tip electrode. The catheter tip can comprise a flexible tip electrode.

Abstract: An insertion tool for inserting a catheter into a body of a patient is disclosed. The insertion tool unifies needle insertion, guidewire advancement, and catheter insertion in a single device. In one embodiment, the insertion tool comprises a housing in which at least a portion of the catheter is initially disposed, a hollow needle distally extending from the housing with at least a portion of the catheter pre-disposed over the needle, and a guidewire pre-disposed within the needle. A guidewire advancement assembly is also included for selectively advancing the guidewire distally past a distal end of the needle in preparation for distal advancement of the catheter. In one embodiment a catheter advancement assembly is also included for selectively advancing the catheter into the patient. Each advancement assembly can include a slide or other actuator that enables a user to selectively advance the desired component.

Abstract: An injection device is disclosed which comprises a housing (140, 240, 440, 740) for a plurality of cartridges (110,310,410,810) each containing a medicament to be administered to a patient. A plurality of needles (120, 220, 320, 420, 720, 820) may be provided in communication with the plurality of cartridges. A delivery mechanism is arranged to deliver medicament through the plurality of cartridges via the plurality of needles. An injection device may comprise a drive member (130) having a cam surface (136) configured to engage a surface of a carrier (150) and rotate the carrier about a pivot (152) and at least one plunger (134) arranged to engage a cylinder in the cartridge.

Abstract: A drug delivery device (100) includes a base (102) having a first region (104) with a drug delivery assembly (106) associated therewith. The drug delivery device also includes an antenna (112) disposed in the first region to radiate an electromagnetic field, the base defining a plane (114) and the antenna disposed in the plane of the base, and an electromagnetic field generator (116) selectively coupled to the antenna.

Abstract: An adapter for use with a syringe and a power injector includes an outer ring having a first end configured for passage of an end of a syringe having at least one flange. An inner ring is disposed coaxially within the outer ring. The inner ring has a first end including at least one flange slot. A magnet fixed relative to the inner ring such that when the syringe end is disposed in the outer ring and the at least one flange engages the at least one flange slot, rotation of the syringe causes rotation of the inner ring and magnet relative to the outer ring.