Patents Examined by Melissa S Mercier
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Patent number: 11564884Abstract: A compound includes an amphiphilic polymer with a hydrophobic block including monomeric units chosen from alkyl (meth)acrylates, alkyl (meth)acrylamides, and combinations thereof; and a hydrophilic cationic block including monomeric units chosen from alkylamino (meth)acrylates, alkylamino (meth)acrylamides, and combinations thereof. The polymer is in the form of a micelle with a central core derived from the hydrophobic block and shell at least partially surrounding the core. The shell includes a plurality of filamentous arms derived from the hydrophilic block and emanating outward from the core. A biological agent is associated with the arms of the micelle.Type: GrantFiled: September 9, 2020Date of Patent: January 31, 2023Assignee: Regents of the University of MinnesotaInventors: Theresa Reineke, Zhe Tan, Yaming Jiang, Mitra S Ganewatta, Timothy P. Lodge
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Patent number: 11559503Abstract: The subject invention provides materials methods for reducing infections in subjects. The materials methods utilize chlorhexidine, which has been found to be surprisingly non-toxic. The lack of toxicity facilitates the use of chlorhexidine in contexts that were not previously thought to be possible.Type: GrantFiled: May 8, 2021Date of Patent: January 24, 2023Assignee: INNOVATION TECHNOLOGIES, INC.Inventors: Carolyn L. Twomey, Gareth Clarke, Samuel Zaidspiner
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Patent number: 11554115Abstract: The present invention provides a quinoline derivative for treating triple-negative breast cancer and use thereof in preparing a pharmaceutical composition for treating a tumor.Type: GrantFiled: March 13, 2019Date of Patent: January 17, 2023Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.Inventors: Xin Tian, Peng Lv, Ling Yang, Xiangjian Wang, Xiquan Zhang, Shanchun Wang, Xunqiang Wang, Hai Jiang
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Patent number: 11553714Abstract: An antimicrobial composition comprising at least two quaternary ammonium compounds selected from: (i) a quaternary ammonium compound having the formula: A4-nSi(R—NHaR1bZ)n and (ii) a quaternary ammonium compound having the formula: NHcR1dZ wherein in each of the at least two quaternary ammonium compounds A, R, R1, a, Z and n are independently selected, and: A is a member selected from the group consisting of alkoxy radicals, alkylether alkoxy radicals, and alkyl radicals; R is a divalent hydrocarbon radical; each R1 is independently a member selected from the group consisting of benzyl, alkyl radicals, alkyl ether hydrocarbon radicals, hydroxyl-containing alkyl radicals, and nitrogen-containing hydrocarbon radicals; Z is a member selected from the group consisting of chloride, bromide, iodide, tosylate, hydroxide, sulfate and phosphate; a is 0, 1 or 2, b is 1, 2 or 3, and the sum of a and b is 3; c is 0, 1, 2 or 3, d is 1, 2, 3 or 4, and the sum of c and d is 4; and n is 1, 2 or 3; and wherein the compositionType: GrantFiled: January 5, 2021Date of Patent: January 17, 2023Assignee: Q Surgical Technologies Ltd.Inventors: Andrew Kemp, Charles Melville Pillans
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Patent number: 11547664Abstract: The disclosure relates to methods and compositions to treat an eosinophilic disease or disorder. More particularly, the disclosure provides methods and compositions for treating eosinophilic esophagitis.Type: GrantFiled: June 6, 2020Date of Patent: January 10, 2023Assignee: The Regents of the University of CaliforniaInventors: Seema S. Aceves, Ranjan Dohil, Quan Nhu
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Patent number: 11540999Abstract: A deodorant stick comprising: at least about 25% of a liquid triglyceride; at least one antimicrobial; a primary structurant with a melting point of at least about 50° C.; and less than 8% of secondary structurants having a melting point of at least about 60° C.; said stick being free of an aluminum salt; and said stick having a hardness from about 80 mm*10 to about 140 mm*10, as measured by penetration with ASTM D-1321 needle.Type: GrantFiled: March 8, 2021Date of Patent: January 3, 2023Assignee: The Procter & Gamble CompanyInventors: David Arthur Sturgis, Lindsey Michelle Britt
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Patent number: 11534411Abstract: Provided is a composition for forming a coating film directly on the skin by an electrostatic spray, the composition being capable of forming a coating film having excellent skin compatibility, adhesion, and scratch resistance, having a good feel, and being easy to peel. A composition for forming a coating film, for forming a coating film composed of fibers directly on the skin by an electrostatic spray, the composition comprising the following Components (a), (b), (c), and (d): (a) a polymer having a coating film forming ability (b) one or more volatile substances selected from the group consisting of an alcohol and a ketone (c) a plasticizer (d) a feel modifier other than Component (c).Type: GrantFiled: February 7, 2019Date of Patent: December 27, 2022Assignee: KAO CORPORATIONInventor: Tatsuya Yoshino
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Patent number: 11534492Abstract: A fluorocarbon emulsion in water for use in fractionated radiotherapy and chemotherapy, wherein said fluorocarbon comprises between 4 and 8 carbon atoms.Type: GrantFiled: February 7, 2021Date of Patent: December 27, 2022Assignee: NuvOx Pharma LLCInventor: Evan C. Unger
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Patent number: 11534410Abstract: Compositions of nanolipid carrier molecules comprising PEG molecules and solid and liquid lipids wherein the PEG has a molecular weight of between about 1000 and 5000 are described. Methods of administering nanolipid carrier molecules are also described. Also described is a method for treating fungal ocular infections by topical ocular administration of nanolipid carrier molecules comprising PEG molecules and solid and liquid lipids wherein the PEG has a molecular weight of between about 1000 and 5000.Type: GrantFiled: August 5, 2019Date of Patent: December 27, 2022Assignee: UNIVERSITY OF MISSISSIPPIInventors: Soumyajit Majumdar, Akash Patil, Prit Lakhani
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Patent number: 11534589Abstract: A medical drug devices for transdermal drug delivery systems (TDDS) comprising a novel iontophoretic polymeric microneedle device and its use in administration of drugs.Type: GrantFiled: September 12, 2018Date of Patent: December 27, 2022Assignees: LTS Lohmann Therapie-Systeme AG, New Jersey Institute of TechnologyInventors: James Paul Ronnander, Laurent Simon
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Patent number: 11529418Abstract: The present invention describes new formulations of semiochemical compounds for mammals in wick diffusers particularly effective in controlling the diffusion of several semiochemicals having different volatilities over long periods of time and independently of the temperature and humidity conditions.Type: GrantFiled: December 21, 2018Date of Patent: December 20, 2022Assignee: CEVA SANTE ANIMALEInventors: Olivier Guerret, Samuel Dufour
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Patent number: 11510955Abstract: The present invention relates to a composition and health functional food for preventing and treating a respiratory inflammation disease using a mixed herbal mixture. Through various experiments, for example, determination of the cell number of BAL (bronchoalveolar lavage) (Experimental Example 1); Determination of CD11b+/Gr-1+ ratio in leukocyte within BAL fluid (Experimental Example 2); Determination of expressed RNA level of inflammatory cytokines in lung tissue (Experimental Example 3); Determination of expressed RNA level of inflammatory cytokines in BALF (Experimental Example 4); Lung histology (Experimental Example 5); Brief Clinical test (Experimental Example 7) etc, it has been verified that the inventive combined extract showed more potent inhibiting effect on respiratory inflammation disease than each herb extract.Type: GrantFiled: May 10, 2018Date of Patent: November 29, 2022Assignees: KT&G CORPORATION, KOREA GINSENG CORP.Inventors: Han-Jae Shin, Hyo Keun Kim, Moon-Yong Lee, Hyo-Min Gwak, Hye-Jeong Min, Young-Sin Kim, Chang Kyun Han, Jongsu Kyung, Gyo In, Jong Han Kim, Sung Won Kim, Kyoung Hwa Jang, Seung-Hyung Kim
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Patent number: 11504307Abstract: A biphasic topical product comprising a hydrophilic phase and a lipophilic phase floating on said hydrophilic phase. A method for preparing biphasic topical products.Type: GrantFiled: September 18, 2018Date of Patent: November 22, 2022Assignee: CMED AESTHETICS S.R.L.Inventor: Elena Bottai
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Patent number: 11504342Abstract: A pharmaceutical active-containing transmucosal delivery device comprises a polymer film comprising a polymer matrix, wherein the film has a pH in the range of about 4 to about 9, and a pharmaceutical active composition disposed on a surface of the polymer film. The composition comprises at least one pharmaceutical active ingredient in the form of particles, and wherein the particles have an average particle size of about 100 nm to about 5 microns, an anti-crystallization agent, and a pH adjusting agent, wherein the concentration of the pharmaceutical active ingredient is at least 20% w/w relative to the total weight of the pharmaceutical active composition. The delivery device exhibits a residence time in the mouth of a subject ranging from about 5 minutes to about 30 minutes and is substantially mucoadhesive to a mucosa surface when placed sublingually under the tongue or placed buccally at the inner lining of the cheek.Type: GrantFiled: February 22, 2019Date of Patent: November 22, 2022Assignee: AVIOR, INC.Inventors: Samarth Vasisht, Niraj Vasisht
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Patent number: 11504395Abstract: The invention is concerned with use of oral inorganic pyrophosphate for preventing and/or reducing tissue calcification, particularly soft tissue calcification, and/or diseases or disorders characterized by low plasma PPi levels, as, e.g.Type: GrantFiled: September 13, 2017Date of Patent: November 22, 2022Assignee: Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek ZiekenhuisInventors: András Váradi, Dóra Dedinszki, Flóra Mária Szeri, Piet Borst, Jan Koenraad Van De Wetering
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Patent number: 11497697Abstract: Disclosed is a method of treating a fine line or wrinkle in a person's skin, the method comprising topically applying to the fine line or wrinkle a composition comprising an effective amount of Commiphora mukul resin or an extract thereof that includes oleo gum resin, glycerin, water, and hyaluronic acid or a salt form thereof, wherein topical application of the composition to the fine line or wrinkle reduces the appearance of the fine line or wrinkle.Type: GrantFiled: September 24, 2020Date of Patent: November 15, 2022Assignee: ALLUSTRA TECHNOLOGIES LLCInventors: Tiffany Florence, Michelle Hines, David Gan, Wanli Zhao
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Patent number: 11497706Abstract: A deodorant stick comprising at least 25% by weight liquid triglyceride; a primary antimicrobial having a water solubility of at most about 90 g/L at 25° C.; a fragrance composition comprising at least about 50% natural oils, essential oils, or a combination thereof; and a primary structurant with a melting point of at least 50° C.; said deodorant stick being free of an aluminum salt; and said deodorant stick having a hardness from about 70 mm*10 to about 140 mm*10, as measured by penetration with ASTM D-1321 needle.Type: GrantFiled: December 17, 2020Date of Patent: November 15, 2022Assignee: The Procter & Gamble CompanyInventors: David Arthur Sturgis, Lindsey Michelle Britt
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Patent number: 11484506Abstract: The present disclosure is directed to a method of preparing a pharmaceutical composition comprising tolerizing immune-modulating particles of polymer-encapsulated gliadin.Type: GrantFiled: February 21, 2017Date of Patent: November 1, 2022Assignee: COUR PHARMACEUTICALS DEVELOPMENT COMPANY, INC.Inventors: Daniel R. Getts, Frank Fokta, Ryan Pearson
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Patent number: 11471399Abstract: A composition intended for the remodelling treatment of a scar, by means of topical application, in particular, as a massage adjuvant. The composition takes the form of a microemulsion, preferably with a gel texture, containing a lipophilic compound, a wound healing agent, a humectant and an emulsifying agent, as well as a small amount of water.Type: GrantFiled: May 23, 2018Date of Patent: October 18, 2022Inventors: Catherine Bidan, Sandy Rattier
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Patent number: 11464719Abstract: Cosmetic and dermatological compositions, including color changing compositions, are provided which typically include a plurality of synthetic particles having a size in the micrometer or nanometer range. Each synthetic particle typically includes one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45; the aggregates having a size larger than about 100 nm and the composition being biodegradable and biocompatible.Type: GrantFiled: September 25, 2018Date of Patent: October 11, 2022Assignee: Northeastern UniversityInventors: Leila Deravi, Camille A. Martin, Amrita Kumar