Patents Examined by Michael A Marcheschi
  • Patent number: 8030058
    Abstract: Advanced islet separation technology incorporates an automated method, automated control methodology, process control interface, and automated apparatus to separate (isolate) and process pancreatic islets in a tissue suspension in physiologic process solution, utilizing microprocessor control and/or microprocessor computer control and software programming (code) to interface and control the process temperature, fluid flow rate, pH, dissolved oxygen concentration, endotoxin concentration, dissolved nitric oxide concentration, nitric oxide synthase activity, proteolytic enzyme activity, and/or pressure of the islet containing physiologic process solution, the extent of islet separation, including real-time data acquisition and recording of process variables.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: October 4, 2011
    Inventors: Daniel J. Benedict, Lorna S. Mosse
  • Patent number: 8030087
    Abstract: The purpose of the present invention is to provide a method to more easily analyze the concentration of glue in an electrolyte solution, while suppressing the degradation of glue during the analysis. There is provided a method for analyzing the concentration of glue contained in an electrolyte solution containing the electrolyte components by using high performance liquid chromatography, where said method comprises a step wherein an electrolyte solution is added into the eluent pH of which has been adjusted equal to or less than 5 by adding acid to an aqueous solution of phosphate of alkaline metal or alkaline earth metal, a step wherein the eluent into which the electrolyte solution has been added is passed through a separation column the exclusion limit molecular weight of which is 4000-6000 for separating the glue and electrolyte components, and a step wherein the separated glue is detected by a detector.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: October 4, 2011
    Assignee: Pan Pacific Copper Co., Ltd.
    Inventors: Masayuki Takahira, Yozo Ishihara, Ikunobu Sumida
  • Patent number: 8017384
    Abstract: A modular membrane supported bioreactor for anaerobic conversion of gas into liquid products including membrane module(s) having a plurality of hollow fibers packed across a cross sectional area of the membrane module in a direction transverse to the axis of the membrane module; a membrane vessel for retaining the membrane module(s) at least partially submerged in a process liquid and isolated from ambient atmosphere; and a gas supply conduit operably connected to the hollow fibers for supplying a process gas to the hollow fiber lumens. The gas supply conduit enables the formation of a biofilm on the outer surface of the hollow fiber wall by interaction of microorganisms with the process gas and the production of a liquid product that mixes with the process liquid.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: September 13, 2011
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Shih-Perng Tsai, Rathin Datta, Rahul Basu, Seong-Hoon Yoon, Richard E. Tobey
  • Patent number: 8017078
    Abstract: A blood cell analyzer is provided with a first detection unit for electrically detecting blood cells in blood sample; a second detection unit for optically detecting blood cells in blood sample; a volume information obtainer for obtaining volume information of red blood cells based on the electrically detected blood cells; a scattered light intensity information obtainer for obtaining a scattered light intensity of red blood cells based on the optically detected blood cells; a first histogram preparer for preparing a first histogram of the volume information of each of red blood cells; a second histogram preparer for preparing a second histogram of the scattered light intensity information of each of red blood cells; a display unit; and a data processor for preparing a screen for displaying on the display unit, the screen including the first and second histograms.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: September 13, 2011
    Assignee: Sysmex Corporation
    Inventors: Jo Linssen, Hans Kalkman
  • Patent number: 8017381
    Abstract: Electroporation on a plurality of samples of membranous structures is performed in an electroporation well plate that includes a frame that can hold a plurality of well strips to form a two-dimensional array of wells, and a set of well strips, the set containing strips that differ in the number of wells while having the same outer dimensions and hence being interchangeable, thereby allowing the user to select strips appropriate for a given electroporation procedure, and allowing the manufacturer to replace defective strips without rejecting an entire well plate when a small number of wells is found to be defective.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: September 13, 2011
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Charles W. Ragsdale, John Morrill
  • Patent number: 8017080
    Abstract: A liquid state detecting apparatus including a detecting element having a heating resistor which generates heat when energized and being disposed in a liquid container for containing a liquid, the apparatus calculating a first difference between a first corresponding value corresponding to a first resistance of the heating resistor acquired after energization of the heating resistor is started and a second corresponding value corresponding to a second resistance of the heating resistor acquired after the heating resistor is energized for a predetermined detection time and obtaining a first concentration of a particular component included in the liquid, the first concentration being associated with the first difference, the apparatus including: an abnormality determination unit, a determination concentration acquiring unit, a concentration difference calculation unit, and a static state determination unit, all as defined herein.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: September 13, 2011
    Assignee: NGK Spark Plug Co., Ltd.
    Inventors: Takeo Sasanuma, Yoshikuni Sato
  • Patent number: 8017091
    Abstract: A device consisting of a low-RPM motor wherein the motor spins a flat disk, a peg is attached to the disk, a stationary spring armature wherein the peg can activate the stationary spring armature as the disk rotates, and a tube containing beads in a fluid positioned in a top plate wherein the spring armature can contact the tube. This device can further include a soft closed-cell foam top mounted on the top plate wherein the tube is inserted and maintained by the foam in such a way as to allow for slight motion of the tube induced by the contact by the spring armature.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: September 13, 2011
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Turan A. Kayagil, Julie A. Richardson
  • Patent number: 8012915
    Abstract: The present invention is a release oil of the general formulae: wherein (Z) is an amine. The solvent extracted portion of the release oil has a ratio of A:B less than 1:5. Less than 10% of the molecular weight distribution of the release oil is less than m/z 1000. The release oil preferably has a viscosity of between 200 and 500 centistokes.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: September 6, 2011
    Assignee: Eastman Kodak Company
    Inventors: Wayne T. Ferrar, Jerry A. Pickering, David F. Cahill, Peter S. Alexandrovich, Andrew J. Hoteling
  • Patent number: 8007744
    Abstract: The present invention relates to a sample container for analyses suitable for medical diagnostics comprising a platform plate having at least one reaction chamber. The reaction chamber has a bottom and a sidewall which form a three-dimensional chamber which is open in the upward direction. The ratio of the numerical value of the surface area of the bottom is relatively large relative to the height of the sidewall. The ratio may be greater than or equal to 30, 35, 40, 45, 50, 60, 70, 80, or 90. The reaction chamber further comprises a binding area on an internal surface of the reaction chamber which may be functionalized for binding at least one chemical entity for use in an assay.
    Type: Grant
    Filed: January 16, 2004
    Date of Patent: August 30, 2011
    Assignee: Greiner Bio-One GmbH
    Inventors: Günther Knebel, Jörg Stappert, Heinrich Jehle, Joachim Kessler
  • Patent number: 7985576
    Abstract: Systems and methods of treating flue gas and wastewater generated by treating the flue gas are disclosed and include introducing the flue gas, a flue gas treatment fluid that removes sulfur dioxide from the flue gas; and an organic acid conditioning agent into a wet-oxidation scrubber/absorber; introducing FGD scrubber wastewater generated by the wet-oxidation scrubber/absorber into an anoxic biological reactor to substantially denitrify the FGD scrubber wastewater; and introducing resulting substantially denitrified FGD scrubber wastewater into an anaerobic biological reactor to substantially reduce the amount of sulfate and/or selected heavy metals in the FGD scrubber wastewater.
    Type: Grant
    Filed: August 22, 2007
    Date of Patent: July 26, 2011
    Assignee: Infilco Degremont, Inc.
    Inventors: Robert F. Kelly, Michael Pudvay, Antonio Lau
  • Patent number: 7981686
    Abstract: A method of assessing body odor using as an index an indicator material comprising an alcohol compound having a mercapto group at the 3-position represented by the following formula (2) and/or a substance that is a derivative of an alcohol compound having a mercapto group at the 3-position, wherein an atom(s) or an atom group(s) is introduced to a mercapto group and/or a hydroxyl group of an alcohol compound having a mercapto group at the 3-position represented by the formula (2):
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: July 19, 2011
    Assignee: Kao Corporation
    Inventors: Masayuki Yabuki, Yoshihiro Hasegawa, Masamoto Matsukane
  • Patent number: 7981668
    Abstract: A method and system for culturing cells, having a substantially airtight enclosure configured to culture cells. The method and system also have a first conduit configured to provide a reduced pressure to the substantially airtight enclosure and a second conduit configured to provide a culture media to the substantially airtight enclosure.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: July 19, 2011
    Assignee: KCI Licensing Inc.
    Inventors: Robert P. Wilkes, Amy K. McNulty, Kristine Kieswetter, Teri D. Feeley, Marisa Schmidt
  • Patent number: 7981189
    Abstract: The invention has a captive tooless fastener for securing the engine intake air filter. The tooless fastener comprises shaft and associated bodies. The body has two arms oriented about 180 degrees apart. The shaft is threaded through a sealing washer and an aperture in a closed end cap of the air filter. The shaft is expanded so it cannot be removed from the end cap. The body's threaded inner diameter mates with a threaded portion of a central shaft in an air filter housing. The body's arms are rotated to screw the fastener and the shaft of the housing together. When tightened, the sealing washer closes the aperture. To remove the air filter, the fastener is unscrewed from the shaft of the housing and in the shaft floats in the aperture. A person in the field can remove the air filter by inserting fingers under the arms and pulling.
    Type: Grant
    Filed: August 29, 2005
    Date of Patent: July 19, 2011
    Assignee: Greenlees Filter LLC
    Inventors: Ronald Troxell, Roy E. Greenlees, Kenneth S. Schultz
  • Patent number: 7976589
    Abstract: Nanoscopic core-shell material additives for high temperature jet aviation fuels are disclosed. The nanometer dimensions of these core-shell material additives materials provide extremely large surface areas to promote chemical reactivity while permitting suspension in liquid fuels and providing unlimited access to all components of an aircraft fuel system. Core-shell technology involves additive encapsulation in a protective, fuel-mimicking shell material.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: July 12, 2011
    Assignee: United States of America as represented by the Secretary of the Air Force
    Inventor: Christopher E. Bunker
  • Patent number: 7972839
    Abstract: The device and method invented provides a unique means to extract and multiply, by the millions, beneficial aerobic microbes found in compost and vermicompost to be applied to soil and plants in liquid form. Compared to many compost tea making devices being sold, the invented device is truly simple and can be dismantled and cleaned in under twenty minutes. Most of the parts are not glued and can be pulled apart. The device and method uses air pumps alone to actually circulate the water and can be used with or without a mesh extractor. This is achieved by the insertion of an air diffuser into the piping used, which infuses the water with oxygen while circulating the water, into either, an extractor containing compost or a body of water containing compost. Concurrently additional diffusers infuse the body of water with oxygen.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: July 5, 2011
    Inventor: Timothy James Wilson
  • Patent number: 7972841
    Abstract: The present invention relates to an exposure device for living cell cultures, the device having a medium chamber common to a plurality of cell culture chambers and medium directing means. The medium chamber, cell culture chambers and the medium directing means may be arranged so as to provide substantially contemporaneous medium exchange at the cell culture chambers.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: July 5, 2011
    Assignee: British American Tobacco (Investments) Limited
    Inventors: Elan David Massey, Justine Williamson, Jeremy Francis Neale Phillips
  • Patent number: 7968335
    Abstract: A cell culturing method employing biomechanical stimulation loading and a system for applying, in in vitro culture, stimulation similar to vertical weight load stimulation or sideward shear stress stimulation acting on tissues in an aboveground living body as repeated biomechanical stimulation to culture cells, culture tissues or a construct including the culture cells. The system includes a mechanical stimulation loading device and a culture receptacle that are placed in a carbon dioxide incubator, and a control computer. The device includes a weight loading piston, a piston raising and lowering stage supporting piston to allow vertical movement of a piston within a designated range, and a stage lifting and lowering mechanism for vertically moving the stage. A computer drives the mechanism in a specified cycle to effect the vertical movement of the stage. When the stage is lowered, a culture in the receptacle is weighted with the piston.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: June 28, 2011
    Inventor: Ken Nakata
  • Patent number: 7964391
    Abstract: A system for testing the toxicity of a test sample comprising: an aqueous suspension of dinoflagellates; a test chamber configured to contain the aqueous suspension of dinoflagellates and the test sample; an optical signal generator configured to emit an excitation signal for exciting the dinoflagellates to emit a fluorescence signal if the dinoflagellates are alive; a first optical transducer configured to produce a first data signal in response to detecting the fluorescence signal; a stimulator configured to introduce a gas into the aqueous suspension for stimulating the dinoflagellates to emit a bioluminescence signal if the dinoflagellates are alive; a second optical transducer configured to produce a second data signal in response to detecting the bioluminescence signal; and a processor configured to compare the first data signal and the second data signal to a control data to generate an output representing the toxicity of the test sample.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: June 21, 2011
    Assignee: United States of America as represented by the Secretary of the Navy
    Inventors: Bryan Bjorndal, David Lapota
  • Patent number: 7943557
    Abstract: A hub bearing, of carbon steel for machine use, which has a long life because of improved resistance to peeling starting from the surface and a grease enclosed in the hub bearing which contains a base oil and a thickener, and in the base oil, the number of naphthenic carbons found by an n-d-M ring analyzing method accounts for 32 to 37% of a whole number of carbon atoms in the base oil. The base oil is a mineral oil or a mixed oil of a mineral oil and a synthetic hydrocarbon oil. The thickener contains 1 to 40 mass % of a urea compound of formula (1): where R2 indicates an aromatic hydrocarbon group having 6 to 15 carbon atoms, and R1 and R3 indicate at least one hydrocarbon group selected from an alicyclic hydrocarbon group and an aromatic hydrocarbon group.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: May 17, 2011
    Assignee: NTN Corporation
    Inventor: Masaki Egami
  • Patent number: 7926681
    Abstract: An apparatus for storing and dispensing a test strip includes a container configured to store a radial array of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. The container has a plurality of radially extending slots formed by a plurality of dividing walls, and each slot is sized to receive a single test strip. A rotatably positionable cover is carried by the container for covering the plurality of radially extending slots. The cover includes an opening, which, when the cover rotates, aligns with one of the slots at a time to allow removal of a single test strip located within the respective slot. Accordingly, the unused test strips remain free of contaminants such as naturally occurring skin oils on a user's hand.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: April 19, 2011
    Assignee: Becton, Dickinson and Company
    Inventors: Robert E. West, John Lovell