Abstract: The present disclosure relates to the fields of nuclear medicine and molecular imaging, and specifically relates to a dual-targeting compound and a preparation method and application thereof. The dual-targeting compound has the following structure shown in Formula (I). The present disclosure also provides a dual-targeting compound capable of being labeled with a radionuclide, and the compound has the following structure shown in Formula (I-1) or Formula (1-2). The dual-targeting compound of the present disclosure has high affinity for an FAP target and an integrin ?v?3 target, can realize synergistic targeting of the FAP target and the integrin ?v?3 target in tumors, and has high uptake in tumors and long retention time in tumors.
Abstract: Methods and systems are disclosed for apparel assembly using three-dimensional printing directly onto fabric apparel materials. Disclosed is a method and system for direct three-dimensional printing and assembly of an article of apparel, including designing a three-dimensional pattern for printing, positioning at least a portion of the article on a tray in a three-dimensional printing system, the portion being positioned substantially flat on the tray, printing a three-dimensional material directly onto the article using the designed pattern, curing the printed material, and removing the article from the three-dimensional printing system.
Abstract: This disclosure provides systems, methods and apparatus, including computer programs encoded on computer storage media, for multi-link aggregation in wireless communications. In one aspect, an apparatus includes a multi-link operation device configured to generate and output for transmission a message indicating a mapping of each of a plurality of traffic identifiers (TIDs) to one or more parameters associated with each of a plurality of wireless links. In some aspects, another apparatus may obtain a message via at least one of a plurality of wireless links indicating a mapping of each of a plurality of TIDs to one or more parameters associated with each the plurality of wireless links, obtain a sequence of packets associated with at least one of the plurality of TIDs via one or more of the plurality of wireless links, and process the sequence of packets based on the mapping indicated via the message.
Type:
Grant
Filed:
July 1, 2022
Date of Patent:
May 28, 2024
Assignee:
QUALCOMM Incorporated
Inventors:
Abhishek Pramod Patil, George Cherian, Sai Yiu Duncan Ho, Alfred Asterjadhi, Lochan Verma
Abstract: A primary package for holding contact lenses is disclosed. It is primarily made from a nucleated polypropylene resin. It has been determined that the nucleated polypropylene resin should be formulated with a polypropylene base resin with greater than 99% polypropylene homopolymer and a primary and secondary stabilizer, which also contains a catalyst acid scavenger; at least one nucleator/clarifier; and at least one catalyst acid scavenger.
Abstract: The present invention relates to the fields of malaria and dengue virus. More specifically, the present invention provides compositions and methods useful for the treatment and prevention of malaria and dengue virus. In particular embodiments, a composition comprises mosquito nectar feed and Chromobacterium sp_Panamam (Csp_P).
Type:
Grant
Filed:
July 29, 2021
Date of Patent:
May 28, 2024
Assignee:
The Johns Hopkins University
Inventors:
George Dimopoulos, Sarah M. Short, Jose L. Ramirez
Abstract: Self-cleaning features for extraction cleaners and attachments for extraction cleaners, such as accessory tools, wands, and/or hoses, are provided. The self-cleaning features are configured redirect cleaning fluid from a fluid supply system of the extraction cleaner into a working air or fluid recovery path of the extraction cleaner, including, but not limited to into the working air or fluid recovery path of a tool, wand, and/or hose of the extraction cleaner.
Type:
Grant
Filed:
April 17, 2023
Date of Patent:
May 28, 2024
Assignee:
BISSELL Inc.
Inventors:
Victoria J. Royale, Aaron P. Griffith, David M. Miller, Michael Luyckx, Brian C. Wolfe, Justin Benacquisto
Abstract: A method of plugging a honeycomb body is disclosed herein, the method comprising: applying a mask layer to a honeycomb body comprising a plurality of channels; forming a plurality of holes in the mask layer such that the plurality of holes are aligned with the plurality of channels; positioning a nozzle defining an opening proximate the mask layer; moving at least one of the nozzle and the honeycomb body relative to one another; and passing a plugging cement through the opening defined by the nozzle against the mask layer such that the plugging cement passes through the plurality of holes in the mask layer and enters the plurality of channels of the honeycomb body.
Type:
Grant
Filed:
June 26, 2019
Date of Patent:
May 28, 2024
Assignee:
Corning Incorporated
Inventors:
Alejandro Aguilar, Richard Dominic Bomba, Kevin Eugene Elliott, Christopher Lane Kerr, Patrick David Tepesch
Abstract: A dross removal device including: a dross robot that is configured to collect a bath surface dross present on a bath surface of a coating bath; a dross sensor that is configured to measure an intensity of infrared light from the bath surface of the coating bath; a dross sensor control device that is configured to specify a position of the bath surface dross according to a temporal change amount in the intensity of the infrared light; and a dross robot control device that is configured to cause the dross robot to collect the bath surface dross at the position specified by the dross sensor control device.
Abstract: This invention relates to, in part, methods and compositions that are useful for the diagnosis, treatment, or prevention of a blinding eye disease, including in the discovery of drugs that are efficacious against these diseases. Diseases include, for example, age related macular degeneration and reticular pseudodrusen disease, and the methods described herein include, for example, the method named delayed near infrared analysis (DNIRA).