Patents Examined by Michael B Pallay
  • Methods and compositions for use with gel dispensers
    Patent number: 10004227
    Abstract: A dispensable hydroalcoholic gel composition is provided. The dispensable hydroalcoholic gel includes a C1-4 alcohol, a polyacrylate thickener, one or more neutralizers, and an additive. The dispensable hydroalcoholic gel exhibits less misdirection during dispensing from a dispensing device than gel compositions that are otherwise identical, but for the presence of the additive.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: June 26, 2018
    Assignee: GOJO Industries, Inc.
    Inventors: David R. Macinga, Sarah L. Edmonds, Kristin E. Hartzell, Kelly A. Dobos, Carol A. Quezada
  • Aromatase inhibitor-releasing intravaginal device
    Patent number: 10004723
    Abstract: An intravaginal device that provides biologically active circulating concentrations of an aromatase inhibitor for at least about of 4 days. Liposome-based and a wax-based formulations were used to assess letrozole diffusion through bovine vaginal mucosa in a diffusion chamber study. The wax-based vehicle was selected for further development of a letrozole intravaginal device based on its steady release rate. The addition of a letrozole-containing gel coating improved initial absorption and hastened the increase on plasma concentrations of the active ingredient, while the letrozole-containing wax-based vehicle maintained prolonged delivery from the intravaginal device.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: June 26, 2018
    Assignee: University of Saskatchewan
    Inventors: Gregg Patrick Adams, Maria Jimena Yapura, Roger A. Pierson, Ildiko Badea
  • Fibrin wafer/disc as a biological carrier for sustained delivery of curcumin
    Patent number: 10004698
    Abstract: Provided herein is a drug delivery system for curcumin comprising fibrinogen, thrombin and curcumin.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: June 26, 2018
    Assignees: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Indian Council of Medical Research
    Inventors: Lissy Kalliyana Krishnan, Lakshmi Sreedharam Pillai
  • Methods for generating high aspect-ratio polymeric particles comprising an active ingredient
    Patent number: 10004223
    Abstract: The present invention relates to methods for generating polymeric particles which comprise one or more active ingredients. The invention also relates to the use of such polymeric particles as a seed treatment. The present technology provides an improved seed treatment suitable for applying plant propagation materials. The seed treatment of the present technology includes the use of high aspect-ratio particles as a seed treatment. The present technology has been found to have advantageous properties associated with the seed treatment including increased adherence of the formulation to the seed and reduced tendency to dust off.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: June 26, 2018
    Assignee: Syngenta Crop Protection LLC
    Inventors: Jeffrey Fowler, Sejong Kim
  • Oral pharmaceutical composition of isotretinoin
    Patent number: 9999606
    Abstract: An oral pharmaceutical composition of isotretinoin and a carrier substrate, having isotretinoin in the form of gel, dispersion, solution or emulsion, which is absorbed onto the carrier substrate to form solid particles, powder, or granules. The oral pharmaceutical composition has enhanced bioavailability. A process is used for preparing the oral composition.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: June 19, 2018
    Assignee: Sun Pharmaceutical Industries Limited.
    Inventors: Rajesh Rao, Anuj Kumar Fanda, Satish Kumar Jain, Romi Barat Singh
  • Product for and method of protecting and increasing friction of animal paws
    Patent number: 9993499
    Abstract: An adhesive and solid particulates adhered to the pads of an animal's paw, the adhesive being cured, thereby increasing the friction of the surface of the pads; and a method of increasing the friction of an animal's paw by applying to clean, dry pads of the animal's paw a layer of uncured adhesive, and while the adhesive layer is uncured, contacting the paw with particulates to adhere the particulates to the pad, then curing the adhesive.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 12, 2018
    Inventors: Stacey Bone, Jeffrey L. Harms
  • Method of protecting active ingredients from degradation during pelleting
    Patent number: 9986749
    Abstract: A system for the protection against degradation during pelleting of one or more physiologically or pharmacologically active substances, comprising compositions in the form of micro particles or granules, particularly for use in the zootechnical and/or veterinary field. The micro particles include a core which contains one or more substances having a pharmacological action, food supplements or diagnostic media, said one or more substances being characterized by the presence, within their chemical structure, of a basic functional group, specifically including an amine functional group. The core comprises also one or more carboxylic acids and/or their salts and eventually one or more excipients. Said core is coated by an outer layer of fats or waxes, and preferably by a mixture of glyceride of fatty acids.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: June 5, 2018
    Assignee: PURINA ANIMAL NUTRITION LLC
    Inventors: Sarah E. Boucher, Jill Davidson, Bill L. Miller
  • Method and topical composition for the treatment of Rosacea and skin erythema using selenium sulfide
    Patent number: 9987304
    Abstract: A method for the treatment of facial Rosacea and skin erythema using selenium sulfide as the sole active ingredient in a topically applied administration to a user's face in combination with an inactive moisturizing ingredient.
    Type: Grant
    Filed: January 3, 2017
    Date of Patent: June 5, 2018
    Inventor: Paul Sutich
  • Transdermal delivery system containing methylphenidate or its salts and methods thereof
    Patent number: 9980921
    Abstract: Disclosed herein is a transdermal delivery system comprising methylphenidate or its salt as an active ingredient. Also provided are methods of delivering a therapeutically effective amount of methylphenidate to a subject for the treatment of a disease condition. The disease condition includes a neurological condition such as Attention Deficit Disorder (ADD) and/or Attention Deficit/Hyperactivity Disorder (ADHD). Kits including the transdermal delivery system and methods of making and using the transdermal delivery system are also provided.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: May 29, 2018
    Assignee: TAHO PHARMACEUTICALS LTD.
    Inventors: Shen-Yung Kao, Taijung Wu, Catherine Lee
  • Non-gelatin enteric soft capsules
    Patent number: 9980916
    Abstract: Enteric soft capsules containing carrageenans as the film-forming polymer have been developed. The enteric soft capsules comprise iota carrageenan and kappa carrageenan, methacrylic acid copolymers, modifeid starch fillers, plasticizers, water, and other excipients. Such enteric soft capsules are stable at pH 1.2 for at least 2 hours and dissolve at pH 6.8 within about 30 minutes. Methods for manufacturing enteric soft capsules comprising carrageenans are also exemplified.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 29, 2018
    Assignee: Patheon Softgels, Inc.
    Inventors: Qi Fang, Josh Heflin, Madhu Hariharan
  • Dry powder formulation
    Patent number: 9980904
    Abstract: This invention provides a process for preparing an inhalable dry powder pharmaceutical formulation comprising the step of heating a sealed wrapper containing a desiccant and an inhaler or a capsule, the inhaler or capsule further containing a dry powder formulation comprising an inhalable active pharmaceutical ingredient and a carrier, wherein the wrapper forms a barrier to the ingress of moisture and wherein heating the sealed wrapper and its contents is performed at a temperature of 30-50° C.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: May 29, 2018
    Assignee: Teva Branded Pharmaceutical Products R&D, Inc.
    Inventors: Mukul Dalvi, Seah Kee Tee
  • Composition for preparing soft capsule shell
    Patent number: 9968560
    Abstract: Provided is a composition for preparing a soft capsule shell that includes a non-animal material, and more particularly a composition for preparing a soft capsule shell, which includes modified starch composed of modified waxy corn starch and modified waxy potato starch, thereby realizing a soft capsule shell having appropriate hardness and elastic strength and delaying a browning phenomenon. The composition includes modified starch composed of modified waxy corn starch and modified waxy potato starch at a weight ratio of 2:8 to 8:2, a modified starch hydrolysate, a gelling agent, a plasticizer and purified water.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: May 15, 2018
    Inventor: Mun Gu Kim
  • Burn wound composition and methods for treating burn wounds
    Patent number: 9968703
    Abstract: Burn wound compositions containing leaf lard, yellow beeswax, Oil of Spike, pine rosin, and aloe vera are described for treatment of first, second, and third degree burn wounds.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: May 15, 2018
    Inventor: Roland C. Schauer
  • Porous silicon drug-eluting particles
    Patent number: 9962396
    Abstract: The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent-permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention. The invention also provides methods of fabricating a drug-eluting particle for releasing therapeutic agents.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: May 8, 2018
    Assignee: pSivida US, Inc.
    Inventors: Paul Ashton, Hong Guo, Jianbing Chen, Leigh T. Canham
  • Rivastigmine transdermal compositions and methods of using the same
    Patent number: 9949935
    Abstract: Rivastigmine transdermal compositions are provided. Aspects of the transdermal compositions include an active agent layer which includes rivastigmine and a solubility modulator, e.g., crosslinked acrylic acid polymer. Also provided are methods of using the transdermal compositions and kits containing the transdermal compositions.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: April 24, 2018
    Assignee: Teikoku Pharma USA, Inc.
    Inventor: Kensuke Murata
  • Skin colored antiperspirant deodorant
    Patent number: 9925128
    Abstract: A deodorant stick having a color component as skin-tone pigmentation, for the discreet wearing of deodorant. The color component matches a color of user's human skin, acting as camouflage that changes its color as it is applied on the skin to match the skin. The deodorant stick includes a plastic casing, containing an interior plastic casing where the interior casing contains a skin-color pigmented deodorant, a fitted plastic cover, a plastic wheel mechanism, and a set of rubber-based grips. The fitted plastic cover may be transparent or of a color that matches the color component included in the deodorant stick. The rubber-based grips matches the color of the color component included in the deodorant stick.
    Type: Grant
    Filed: December 25, 2013
    Date of Patent: March 27, 2018
    Inventor: Donna Marie Kiel
  • Oral care composition containing pumice and calcium carbonate
    Patent number: 9913796
    Abstract: Disclosed are oral care compositions comprising an abrasive system, wherein the abrasive system comprises (a) a first particulate abrasive comprising at least 20 wt % pumice, based on the weight of the oral care composition, having an average particle size of from 20 to 300 microns; and (b) a second particulate abrasive comprising calcium carbonate having an average particle size of from 2 to 13 microns. There is also disclosed a method of cleaning teeth comprising applying the oral care composition to a tooth surface, the oral care composition being applied as a paste disposed in a prophy cup.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: March 13, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: Andre Morgan, Vyoma Patel, Marilou Joziak, Michael Prencipe
  • Taurine compositions suitable for inhalation
    Patent number: 9907754
    Abstract: The invention discloses spray-dried compositions for inhalation and methods for preparing such powder compositions. The compositions of the invention are produced by spray-drying taurine under conditions that (i) retain the physical and chemical stability of the composition during spray drying and upon storage, (ii) protect the powder composition from aggregation and (iii) provide particles suitable for aerosolization.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: March 6, 2018
    Assignee: VECTURA LIMITED
    Inventors: David Farrow, Katie Coggins
  • Wet-electrospun biodegradable scaffold and uses therefor
    Patent number: 9901659
    Abstract: A cell growth matrix is provided that comprises a biodegradable elastomeric polymer electrodeposited concurrently with a sprayed or electrosprayed liquid that is a physiological solution or which comprises a mammalian blood product such as serum, plasma or platelet rich plasma. The matrix is useful as a cell-growth matrix and for repair of a tissue in a mammal, for instance by implantation in a mammal at a site in need of repair, such as in an abdominal wall.
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: February 27, 2018
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Yi Hong, Nicholas J. Amoroso, Kazuro Lee Fujimoto, Ryotaro Hashizume, William R. Wagner
  • Low density lipoprotein nanocarriers for targeted delivery of omega-3 polyunsaturated fatty acids to cancer
    Patent number: 9889092
    Abstract: An LDL nanocarrier is an effective and appropriate transporter for DHA in biological systems. The LDL-DHA nanoparticle was shown to be preferentially cytotoxic to malignant liver cells. These LDL-DHA nanoparticles show great promise as an anti-cancer agent. In particular embodiments, the nanoparticles exhibit a diameter of 15 to 30 nm.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: February 13, 2018
    Assignee: The Board of Regents of the University of Texas System
    Inventor: Ian R. Corbin