Patents Examined by Michael B Pallay
  • Instrument for skin treatment
    Patent number: 10821081
    Abstract: An apparatus configured to result in a penetration of one or more gasses into a dermis of biological skin, wherein the apparatus includes a fluid reservoir configured to contain an amount of a liquid in contact with a portion of a person's skin, and a nanobubble generator configured to inject nanobubbles into the liquid, wherein the nanobubbles contain the one or more gasses. The contact of the liquid containing the nanobubbles with the person's skin results in a cutaneous uptake of a gas contained in the nanobubbies into the person's skin, which may be beneficial in treating an ailment, such as diabetic peripheral neuropathy.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: November 3, 2020
    Assignee: Nanobubbling, LLC
    Inventors: Zvi Yaniv, Igor Alexander Goldman
  • Heat stable hyaluronic acid compositions for dermatological use
    Patent number: 10806821
    Abstract: The disclosure provides hyaluronic acid (HA) gel formulations and methods for treating the appearance of the skin. The formulations contain hyaluronic acid and at least one additional ingredient. Methods for treating lines, wrinkles, fibroblast depletions, and scars with the disclosed composition are provided as well.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: October 20, 2020
    Assignee: ALLERGAN INDUSTRIE, SAS
    Inventors: Cecile Gousse, Pierre F. Lebreton, Nicholas Prost
  • Time released weed treatment system device and method
    Patent number: 10765113
    Abstract: This invention provides for a time released weed treatment system for maintaining a weed free garden space. This system enables creation and easy maintenance of weed free garden areas to allow for stronger overall garden health as well as provide greater control and use of space in gardening. The time release-based weed treatment system uses an elongated planar strip impregnated with the time release weed control/treatment mechanism. A plurality of spaced-apart cross cuts is formed along longitudinal edges of the strip to allow bending of the strip into an arcuate or angular configuration. Anchoring pins are provided for securing the strip flat on the ground in the selected location.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: September 8, 2020
    Inventor: David Meyer, Sr.
  • Nail polish formulation
    Patent number: 10744349
    Abstract: A formulation for a nail polish composition which is curable with UV light is provided. The composition can be applied in a single coating and does not include solvents such as tolualene, dibutyl phthalate, or formaldehyde. The coating once cured provides multi-coating results using only a single coating and can be covered with an optional gloss or other decorative top coating.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: August 18, 2020
    Inventor: Christina Flint
  • Transcutaneous vaccine formulations and methods
    Patent number: 10722568
    Abstract: Provided are topical delivery systems and methods for treating and/or preventing a disease or disorder in a subject, or for eliciting an immune response in a subject including applying, to at least a portion of the subject's post-auricular region, a topical delivery system including a therapeutically effective amount of a topical pharmaceutical composition comprising at least one active agent and a pharmaceutically acceptable carrier and/or adjuvant. The topical pharmaceutical composition can include a topical immunogenic composition. The topical delivery system can further include a flexible substrate in communication with the topical immunogenic composition. The subject can be a pediatric subject.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: July 28, 2020
    Assignee: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
    Inventor: Lauren O. Bakaletz
  • Stable hydrogel compositions including additives
    Patent number: 10722444
    Abstract: The present specification generally relates to an injectable dermal filler composition that includes crosslinked hyaluronic acid-based polymer and an antioxidant.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: July 28, 2020
    Assignee: Allergan Industrie, SAS
    Inventors: Cécile Gousse, Sébastien Pierre, Pierre F. Lebreton
  • Sprinkle formulations of acamprosate
    Patent number: 10709668
    Abstract: The present invention provides an orally-administrable, pharmaceutical formulation comprising: a plurality of pellets, wherein: the pellets comprise a core, a sustained release coating, and an enteric coating; and the core comprises an active ingredient and a diluent.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: July 14, 2020
    Assignee: CONFLUENCE PHARMACEUTICALS, LLC
    Inventors: Steven L. Johns, Kenneth G. Payie, Badrinath R. Doniparthi, Shivaraj B. Munianjanappa
  • Topical sunscreen emulsions
    Patent number: 10709649
    Abstract: The invention relates to topical sunscreen emulsion comprising an oil phase and a water phase, wherein said emulsion comprises a phosphate ester emulsifier, phytantriol and an amount of at least 1 wt.-% based on the total weight of the topical sunscreen emulsion of at least one UV-filter substance. Furthermore, the invention relates to the use of phytantriol for improving the water resistance of such topical sunscreen emulsions.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: July 14, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: Cyrille Deshayes, Christine Mendrok-Edinger
  • Synergistic photoprotective compositions
    Patent number: 10709654
    Abstract: A photoprotective composition can be utilized for a variety of cosmetic compositions. A photoprotective composition comprises one or more photoactive agents, and a synergistic combination of polymers. The photoprotective composition can provide a substantially a complete film. The photoprotective composition may comprise an alkyl dimethicone, a polymer with ester linkages, and a phenyl silicone or stearate. The photoprotective composition can further comprise abietic acid and ester derivatives. The photoprotective composition can be a liquid such that it is easily and consistently dispensed from a bottle, pump or spray.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: July 14, 2020
    Assignee: EDGEWELL PERSONAL CARE BRANDS, LLC
    Inventors: Laura Spaulding, James SaNogueira, Geng Li
  • Flexible means for determining the extent of debridement required to remove non-viable tissue
    Patent number: 10695228
    Abstract: A flexible dressing for applying to a tissue site for determining the extent of debridement required to remove non-viable tissue is disclosed. Some embodiments of the dressing may be in the form of a multi-layer drape having an integrated tissue viability indicator system. Some embodiments may also include a system of shapes or a grid pattern printed or embossed on a surface of the drape for providing guidance during an ensuing debridement or amputation procedure.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: June 30, 2020
    Assignee: KCI Licensing, Inc.
    Inventors: Justin Alexander Long, Sandra Garcia-Osborne, Timothy Mark Robinson, Christopher Brian Locke, Daniel W. Dekruif
  • Thermo-kinetic mixing for pharmaceutical applications
    Patent number: 10668085
    Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: June 2, 2020
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLC
    Inventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams, III
  • Orodispersible dosage unit containing an estetrol component
    Patent number: 10660903
    Abstract: An orodispersible solid pharmaceutical dosage unit having a weight between 30 and 1,000 mg is disclosed. The dosage unit comprises (a) 0.1-25 wt. % of estetrol particles containing at least 80 wt. % of an estetrol component selected from estetrol, estetrol esters and combinations thereof; and (b) 75-99.9 wt. % of one or more pharmaceutically acceptable excipients. The solid dosage unit comprises at least 100 ?g of the estetrol component and can be obtained by a process that comprises compressing a dry blend of estetrol particles and one or more pharmaceutically acceptable excipients into a solid dosage unit. The solid dosage unit is easy to manufacture and suited for sublingual, buccal or sublabial administration.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: May 26, 2020
    Assignee: ESTETRA SPRL
    Inventors: Séverine Francine Isabelle Jaspart, Johannes Jan Platteeuw, Denny Johan Marijn Van Den Heuvel
  • Water-soluble hyaluronic acid gel and method for producing same
    Patent number: 10639266
    Abstract: To provide a water-soluble hyaluronic acid gel which does not contain a large amount of an organic solvent, wherein hyaluronic acid is not chemically modified. A water-soluble hyaluronic acid gel which contains hyaluronic acid, a polyhydric alcohol, an acid, and 0-10% by mass of a water-soluble organic solvent.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: May 5, 2020
    Assignee: RITAPHARMA, CO., LTD
    Inventor: Kunio Yoneto
  • Long-lasting disinfestation article and method of manufacture thereof
    Patent number: 10638749
    Abstract: A disinfestation article includes a base, external voids and internal voids formed in the base, pesticidal compound disposed in the external and internal voids. The pesticidal compound disposed in the external void being exposed to a surface of the base. The article may further comprise channels connecting one of the internal voids to one of the external voids. The pesticidal compound contains pesticidal particles selected from pyrethroid family or the like. Also claimed is a method of manufacturing which includes mixing pesticidal particles into a molten polymer material to form a mixture, injecting the mixture into a mold to form a molded part, and cooling the molded part to form said disinfestation article.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: May 5, 2020
    Inventor: Dong Lin Eugene Tan
  • Nanobubbler
    Patent number: 10624841
    Abstract: A nanobubbler includes a porous ceramic material, a first inlet configured to inject a gas into the porous ceramic material, wherein the porous ceramic material is configured to emit nanobubbles into the chamber from the surface in response to the injection of the gas, a chamber positioned adjacent to a surface of the porous ceramic material, a second inlet configured to inject a liquid into the chamber so that the nanobubbles are dislodged from the surface of the porous ceramic material into the liquid, and an outlet configured to output from the chamber the liquid infused with the nanobubbles. The nanobubbles infused into the liquid have an average diameter of less than 500 nanometers.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: April 21, 2020
    Assignee: Nanobubbling, LLC
    Inventors: Zvi Yaniv, Igor Alexander Goldman
  • Cell culture method using bone marrow-like structure, and porous polyimide film for healing bone injury site
    Patent number: 10590388
    Abstract: The present invention relates to a method for culturing bone marrow cells, in which bone marrow cells are applied to a porous polyimide film and cultured. Moreover, the present invention relates to a porous polyimide film for healing a bone injury site.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: March 17, 2020
    Assignees: UBE INDUSTRIES, LTD., KURUME UNIVERSITY
    Inventors: Keisuke Ohta, Shingo Hirashima, Masahiko Hagihara, Motohisa Shimizu
  • Bolus and method for producing same
    Patent number: 10589125
    Abstract: Provided is a bolus formed of a hydrogel, wherein the hydrogel includes water, a polymer, and a mineral, and wherein the bolus is applied to a patient who receives a radiation therapy.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: March 17, 2020
    Assignee: Ricoh Company, Ltd.
    Inventors: Tatsuya Niimi, Yoshihiro Norikane, Takashi Matsumura, Hiroshi Iwata, Hiroyuki Naito
  • C-Met modulator pharmaceutical compositions
    Patent number: 10548888
    Abstract: Pharmaceutical compositions and unit dosage forms comprising Compound (I) are disclosed.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: February 4, 2020
    Assignee: EXELIXIS
    Inventors: Jo Ann Wilson, Khalid Shah
  • Transdermal delivery system containing methylphenidate or its salts and methods thereof
    Patent number: 10537532
    Abstract: Disclosed herein is a transdermal delivery system comprising methylphenidate or its salt as an active ingredient. Also provided are methods of delivering a therapeutically effective amount of methylphenidate to a subject for the treatment of a disease condition. The disease condition includes a neurological condition such as Attention Deficit Disorder (ADD) and/or Attention Deficit/Hyperactivity Disorder (ADHD). Kits including the transdermal delivery system and methods of making and using the transdermal delivery system are also provided.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: January 21, 2020
    Assignee: TAHO PHARMACEUTICALS LTD.
    Inventors: Shen-Yung Kao, Taijung Wu, Catherine Lee
  • Cell culture method using bone marrow-like structure, and porous polyimide film for healing bone injury site
    Patent number: 10508264
    Abstract: The present invention relates to a method for culturing bone marrow cells, in which bone marrow cells are applied to a porous polyimide film and cultured. Moreover, the present invention relates to a porous polyimide film for healing a bone injury site.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: December 17, 2019
    Assignees: UBE INDUSTRIES, LTD., KURUME UNIVERSITY
    Inventors: Keisuke Ohta, Shingo Hirashima, Masahiko Hagihara, Motohisa Shimizu